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The map label for this gene is moaB [H]

Identifier: 126699319

GI number: 126699319

Start: 1986855

End: 1987358

Strand: Direct

Name: moaB [H]

Synonym: CD1712

Alternate gene names: 126699319

Gene position: 1986855-1987358 (Clockwise)

Preceding gene: 126699318

Following gene: 126699320

Centisome position: 46.31

GC content: 29.37

Gene sequence:

>504_bases
ATGTTTAATGTTGCAATTATAACACTTAGTGATAAAGGATATGAAGGAAAAAGAGAAGATATAACAGGAAAAAAGTTAAC
TGAATTTGTTGAAAATACAGGAGCTTATAAAGTTACTGAATATGTACTTATAAAAGATGATAAGGAAATGCTAAAGGAAA
ATATTATAAGACTTTGTAATAGTAATAAAATAGATTTAATTCTTACAAATGGAGGTACTGGTTTTTCAAAAAGAGATATA
ACCCCAGAAGCAACTAAGGAAGTGTTGGAAAAAGAAATACCAGGTCTGAGCGAATATATGAGAATGAAATCCACAGAAAT
TACTAAAAAGGCCATACTAAGTAGGGGTGTAAGTGGAATAAGAAATAATTCTATAATAATAAATTTACCTGGAAGTCCTA
AAGGTGCAGTTGAAAATCTAAGTTTTATAATTGATGTTTTAGACCATGGCATAGAAGTTTTAAGAGGAGAAGCTACAGAA
TGTGCCACTAAAAAAAGTGAATAG

Upstream 100 bases:

>100_bases
TGTTATATTGCTGATAGAAAAGAGAATAAAAGAAAATAGGTTTTATTAAAAGAGATTTTTATTTATAGGACTTAATCAAT
GTATAGAGGGGTGAGAACGT

Downstream 100 bases:

>100_bases
TATATAATCTAGATAGATAAAAAATAGACAAAGAGGTAGATAAAGTATGATTGATAAGTATGGAAGAAAAATAGACTACC
TTCGTATTTCACTTACAGAT

Product: molybdenum cofactor biosynthesis protein

Products: NA

Alternate protein names: MPT adenylyltransferase [H]

Number of amino acids: Translated: 167; Mature: 167

Protein sequence:

>167_residues
MFNVAIITLSDKGYEGKREDITGKKLTEFVENTGAYKVTEYVLIKDDKEMLKENIIRLCNSNKIDLILTNGGTGFSKRDI
TPEATKEVLEKEIPGLSEYMRMKSTEITKKAILSRGVSGIRNNSIIINLPGSPKGAVENLSFIIDVLDHGIEVLRGEATE
CATKKSE

Sequences:

>Translated_167_residues
MFNVAIITLSDKGYEGKREDITGKKLTEFVENTGAYKVTEYVLIKDDKEMLKENIIRLCNSNKIDLILTNGGTGFSKRDI
TPEATKEVLEKEIPGLSEYMRMKSTEITKKAILSRGVSGIRNNSIIINLPGSPKGAVENLSFIIDVLDHGIEVLRGEATE
CATKKSE
>Mature_167_residues
MFNVAIITLSDKGYEGKREDITGKKLTEFVENTGAYKVTEYVLIKDDKEMLKENIIRLCNSNKIDLILTNGGTGFSKRDI
TPEATKEVLEKEIPGLSEYMRMKSTEITKKAILSRGVSGIRNNSIIINLPGSPKGAVENLSFIIDVLDHGIEVLRGEATE
CATKKSE

Specific function: Catalyzes the adenylation of molybdopterin as part of the biosynthesis of the molybdenum-cofactor [H]

COG id: COG0521

COG function: function code H; Molybdopterin biosynthesis enzymes

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the moaB/mog family [H]

Homologues:

Organism=Homo sapiens, GI10880983, Length=154, Percent_Identity=43.5064935064935, Blast_Score=133, Evalue=9e-32,
Organism=Homo sapiens, GI66932975, Length=154, Percent_Identity=43.5064935064935, Blast_Score=132, Evalue=1e-31,
Organism=Escherichia coli, GI1786190, Length=156, Percent_Identity=35.2564102564103, Blast_Score=99, Evalue=2e-22,
Organism=Escherichia coli, GI1787000, Length=141, Percent_Identity=29.7872340425532, Blast_Score=76, Evalue=9e-16,
Organism=Caenorhabditis elegans, GI17564954, Length=158, Percent_Identity=36.7088607594937, Blast_Score=106, Evalue=4e-24,
Organism=Drosophila melanogaster, GI17136978, Length=150, Percent_Identity=36, Blast_Score=110, Evalue=4e-25,
Organism=Drosophila melanogaster, GI24638841, Length=150, Percent_Identity=36, Blast_Score=110, Evalue=4e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020817
- InterPro:   IPR008284
- InterPro:   IPR001453 [H]

Pfam domain/function: PF00994 MoCF_biosynth [H]

EC number: NA

Molecular weight: Translated: 18498; Mature: 18498

Theoretical pI: Translated: 6.04; Mature: 6.04

Prosite motif: PS01078 MOCF_BIOSYNTHESIS_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFNVAIITLSDKGYEGKREDITGKKLTEFVENTGAYKVTEYVLIKDDKEMLKENIIRLCN
CCEEEEEEEECCCCCCCCCCCCHHHHHHHHHCCCCEEEEEEEEEECCHHHHHHHHHHHHC
SNKIDLILTNGGTGFSKRDITPEATKEVLEKEIPGLSEYMRMKSTEITKKAILSRGVSGI
CCCEEEEEECCCCCCCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCC
RNNSIIINLPGSPKGAVENLSFIIDVLDHGIEVLRGEATECATKKSE
CCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHCCCCC
>Mature Secondary Structure
MFNVAIITLSDKGYEGKREDITGKKLTEFVENTGAYKVTEYVLIKDDKEMLKENIIRLCN
CCEEEEEEEECCCCCCCCCCCCHHHHHHHHHCCCCEEEEEEEEEECCHHHHHHHHHHHHC
SNKIDLILTNGGTGFSKRDITPEATKEVLEKEIPGLSEYMRMKSTEITKKAILSRGVSGI
CCCEEEEEECCCCCCCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCC
RNNSIIINLPGSPKGAVENLSFIIDVLDHGIEVLRGEATECATKKSE
CCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9923682 [H]