| Definition | Clostridium difficile 630 chromosome, complete genome. |
|---|---|
| Accession | NC_009089 |
| Length | 4,290,252 |
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The map label for this gene is kdpA [H]
Identifier: 126699195
GI number: 126699195
Start: 1844994
End: 1846688
Strand: Direct
Name: kdpA [H]
Synonym: CD1591
Alternate gene names: 126699195
Gene position: 1844994-1846688 (Clockwise)
Preceding gene: 126699194
Following gene: 126699196
Centisome position: 43.0
GC content: 32.68
Gene sequence:
>1695_bases TTGGGGGGAACAATTTTTATGGTGCAGATAGTAATAGTGTTAGCGATTTTTATGATTTTAGTAATACCTATGGGCAAGTA TTTATATCATATAGCTACTAATCAAAAAACATTTGGAGATAGACTATTTGATAAAGTGGACAATTTTATATATAAGGTAT GTAGTATAGATAAGAAAAAAGAAATGAACTGGAAACAGTATGCATTAGCTTTATTATTTACAAATGCAGTTATGGTATTT ATAGGATATATCATACTTAGAACTCAAAGTATGCATATTTTTAATCCAAGTGGAATTAAAAGTATGGAACAAGGACTATC ATTTAATACAATAATAAGTTTTATGACAAATACAAATCTTCAACATTATTCAGGTGAATCAGGACTTTCATACTTTAGTC AGATGACAGTGATAATATATATGATGTTTACATCAGCTGCAACAGGATATGCGGCTGCTATGGCATTTGTAAGAGGTCTA GTCGGTAAAAAGAAAACATTGGGAAATTTTTATGTAGATTTAATTAGGATAACAACAAGAGTACTTTTACCAGGAGCTTT AATTATTGGGCTTATATTAGTTACACAAGGAGTACCACAAACTTTTGCTGGGACAGAAACAGTGACTACTATAGAAGGAA AGCTTCAAGATATAGCTAGAGGTCCTGTGGCAGCTCTTGAATCAATAAAACATTTAGGAACAAATGGTGGTGGATTCTTT GGTTCAAATTCATCACACCCATTTGAAAATCCAACAATAATATCAAATATAGTAGAAATATTATCTATGATGATATTACC AGGAGCTTGTGTTGTTGCATTTGGTCACATGATAAAGAATAAAAAACAAGGTTGGGTTGTGTTTGGCGCAATGTCAATCA TATTTTTAATAGGTCTAGTAGTGTGCTTTAAAGCAGAAAGTGCAGGAAATCCTATTTTATCACAATTAGGGCTTAATCAA AGTATGGGAAGTATGGAAGGTAAGGAAGTTAGATTTGGTATAGCACAATCATCATTATTCACAACAGTGACTACTTCCTT TACGACAGGTACAGTTAATAATATGCATGATACACTGACTCCTTTAGGAGGATTAGTACCACTTTTAAATATGATGCTAA ATGTAGTATTTGGTGGTAAAGGCGTAGGTCTGATGAATATGTTGATGTACGCTATAATAGCAGTATTCTTATGTGGATTA ATGGTAGGAAGAACACCAGAGTTTTTAACTAAGAAAATCGAAGGAAAAGAAATGAAGCTTATTGCTTTACTTATTATATT ACATCCACTTTTAATACTAATGTTCTCTGGTCTTTCAGTAGCAATACCAGCAGGGCTTGAAGGAATTTCAAATCCTGGAT TCCATGGATTATCACAGGTATTGTATGAGTTTGCATCTTCAGCAGCCAATAATGGTTCAGGATTTGAAGGTCTAGGAGAT AACACTATGTTTTGGAATATAACAACAGGTGTAGTTATGTTCTTTGGAAGATATGTGTCTATTATAGTACTACTAGCAAT ATCAAGTTTGTTAGCATCTAAAAAAGCTGTAAATGAAAGTATAGGAACACTTAGAACGGATAATTTTACATTTACAATAG TTTTAGTACTTGTTGTTTTAATTGTTGGTGCTTTAACATTTTTCCCAGCCTTAGCGCTTGGACCTATTTCGGAGCATCTA GTGTTGTGGCACTAA
Upstream 100 bases:
>100_bases TTTCTGGCAGTTGTAATTATAATGTTAATAATATATTTGGTATATGCGCTTATTAATCCTGAAAAATTTTAAACAGTATA AGGCTAATAAGTAAGTTGAA
Downstream 100 bases:
>100_bases AAAATTGGGAGGGAGTAAAGTTTTATGGAAACTAAAAAAACAAAGTTTATTACAAAAGATATTTTCAAAACTTCCATTAT AGAAGCTTTTAAAAAATTAA
Product: potassium-transporting ATPase subunit A
Products: NA
Alternate protein names: ATP phosphohydrolase [potassium-transporting] A chain; Potassium-binding and translocating subunit A; Potassium-translocating ATPase A chain [H]
Number of amino acids: Translated: 564; Mature: 563
Protein sequence:
>564_residues MGGTIFMVQIVIVLAIFMILVIPMGKYLYHIATNQKTFGDRLFDKVDNFIYKVCSIDKKKEMNWKQYALALLFTNAVMVF IGYIILRTQSMHIFNPSGIKSMEQGLSFNTIISFMTNTNLQHYSGESGLSYFSQMTVIIYMMFTSAATGYAAAMAFVRGL VGKKKTLGNFYVDLIRITTRVLLPGALIIGLILVTQGVPQTFAGTETVTTIEGKLQDIARGPVAALESIKHLGTNGGGFF GSNSSHPFENPTIISNIVEILSMMILPGACVVAFGHMIKNKKQGWVVFGAMSIIFLIGLVVCFKAESAGNPILSQLGLNQ SMGSMEGKEVRFGIAQSSLFTTVTTSFTTGTVNNMHDTLTPLGGLVPLLNMMLNVVFGGKGVGLMNMLMYAIIAVFLCGL MVGRTPEFLTKKIEGKEMKLIALLIILHPLLILMFSGLSVAIPAGLEGISNPGFHGLSQVLYEFASSAANNGSGFEGLGD NTMFWNITTGVVMFFGRYVSIIVLLAISSLLASKKAVNESIGTLRTDNFTFTIVLVLVVLIVGALTFFPALALGPISEHL VLWH
Sequences:
>Translated_564_residues MGGTIFMVQIVIVLAIFMILVIPMGKYLYHIATNQKTFGDRLFDKVDNFIYKVCSIDKKKEMNWKQYALALLFTNAVMVF IGYIILRTQSMHIFNPSGIKSMEQGLSFNTIISFMTNTNLQHYSGESGLSYFSQMTVIIYMMFTSAATGYAAAMAFVRGL VGKKKTLGNFYVDLIRITTRVLLPGALIIGLILVTQGVPQTFAGTETVTTIEGKLQDIARGPVAALESIKHLGTNGGGFF GSNSSHPFENPTIISNIVEILSMMILPGACVVAFGHMIKNKKQGWVVFGAMSIIFLIGLVVCFKAESAGNPILSQLGLNQ SMGSMEGKEVRFGIAQSSLFTTVTTSFTTGTVNNMHDTLTPLGGLVPLLNMMLNVVFGGKGVGLMNMLMYAIIAVFLCGL MVGRTPEFLTKKIEGKEMKLIALLIILHPLLILMFSGLSVAIPAGLEGISNPGFHGLSQVLYEFASSAANNGSGFEGLGD NTMFWNITTGVVMFFGRYVSIIVLLAISSLLASKKAVNESIGTLRTDNFTFTIVLVLVVLIVGALTFFPALALGPISEHL VLWH >Mature_563_residues GGTIFMVQIVIVLAIFMILVIPMGKYLYHIATNQKTFGDRLFDKVDNFIYKVCSIDKKKEMNWKQYALALLFTNAVMVFI GYIILRTQSMHIFNPSGIKSMEQGLSFNTIISFMTNTNLQHYSGESGLSYFSQMTVIIYMMFTSAATGYAAAMAFVRGLV GKKKTLGNFYVDLIRITTRVLLPGALIIGLILVTQGVPQTFAGTETVTTIEGKLQDIARGPVAALESIKHLGTNGGGFFG SNSSHPFENPTIISNIVEILSMMILPGACVVAFGHMIKNKKQGWVVFGAMSIIFLIGLVVCFKAESAGNPILSQLGLNQS MGSMEGKEVRFGIAQSSLFTTVTTSFTTGTVNNMHDTLTPLGGLVPLLNMMLNVVFGGKGVGLMNMLMYAIIAVFLCGLM VGRTPEFLTKKIEGKEMKLIALLIILHPLLILMFSGLSVAIPAGLEGISNPGFHGLSQVLYEFASSAANNGSGFEGLGDN TMFWNITTGVVMFFGRYVSIIVLLAISSLLASKKAVNESIGTLRTDNFTFTIVLVLVVLIVGALTFFPALALGPISEHLV LWH
Specific function: One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions [H]
COG id: COG2060
COG function: function code P; K+-transporting ATPase, A chain
Gene ontology:
Cell location: Cell membrane; Multi-pass membrane protein (Probable) [H]
Metaboloic importance: Non_Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Belongs to the kdpA family [H]
Homologues:
Organism=Escherichia coli, GI1786915, Length=553, Percent_Identity=45.750452079566, Blast_Score=455, Evalue=1e-129,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR004623 [H]
Pfam domain/function: PF03814 KdpA [H]
EC number: =3.6.3.12 [H]
Molecular weight: Translated: 61095; Mature: 60963
Theoretical pI: Translated: 9.46; Mature: 9.46
Prosite motif: NA
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.7 %Cys (Translated Protein) 5.3 %Met (Translated Protein) 6.0 %Cys+Met (Translated Protein) 0.7 %Cys (Mature Protein) 5.2 %Met (Mature Protein) 5.9 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MGGTIFMVQIVIVLAIFMILVIPMGKYLYHIATNQKTFGDRLFDKVDNFIYKVCSIDKKK CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCCHH EMNWKQYALALLFTNAVMVFIGYIILRTQSMHIFNPSGIKSMEQGLSFNTIISFMTNTNL CCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEECCCCHHHHHHCCCHHHHHHHHHCCCC QHYSGESGLSYFSQMTVIIYMMFTSAATGYAAAMAFVRGLVGKKKTLGNFYVDLIRITTR CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHH VLLPGALIIGLILVTQGVPQTFAGTETVTTIEGKLQDIARGPVAALESIKHLGTNGGGFF HHHHHHHHHHHHHHHCCCCCCCCCCCCEEEHHHHHHHHHCCHHHHHHHHHHCCCCCCCCC GSNSSHPFENPTIISNIVEILSMMILPGACVVAFGHMIKNKKQGWVVFGAMSIIFLIGLV CCCCCCCCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCEEEEHHHHHHHHHHHH VCFKAESAGNPILSQLGLNQSMGSMEGKEVRFGIAQSSLFTTVTTSFTTGTVNNMHDTLT HHHCCCCCCCHHHHHHCCCCCCCCCCCCCEEEEHHHHHHHHHHHHCCCCCCCCCHHHHHH PLGGLVPLLNMMLNVVFGGKGVGLMNMLMYAIIAVFLCGLMVGRTPEFLTKKIEGKEMKL HHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHCCCCHHHH IALLIILHPLLILMFSGLSVAIPAGLEGISNPGFHGLSQVLYEFASSAANNGSGFEGLGD HHHHHHHHHHHHHHHCCCCEECCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCC NTMFWNITTGVVMFFGRYVSIIVLLAISSLLASKKAVNESIGTLRTDNFTFTIVLVLVVL CCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEECCCHHHHHHHHHHHH IVGALTFFPALALGPISEHLVLWH HHHHHHHHHHHHHCCCCCCCEECC >Mature Secondary Structure GGTIFMVQIVIVLAIFMILVIPMGKYLYHIATNQKTFGDRLFDKVDNFIYKVCSIDKKK CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCCHH EMNWKQYALALLFTNAVMVFIGYIILRTQSMHIFNPSGIKSMEQGLSFNTIISFMTNTNL CCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEECCCCHHHHHHCCCHHHHHHHHHCCCC QHYSGESGLSYFSQMTVIIYMMFTSAATGYAAAMAFVRGLVGKKKTLGNFYVDLIRITTR CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHH VLLPGALIIGLILVTQGVPQTFAGTETVTTIEGKLQDIARGPVAALESIKHLGTNGGGFF HHHHHHHHHHHHHHHCCCCCCCCCCCCEEEHHHHHHHHHCCHHHHHHHHHHCCCCCCCCC GSNSSHPFENPTIISNIVEILSMMILPGACVVAFGHMIKNKKQGWVVFGAMSIIFLIGLV CCCCCCCCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCEEEEHHHHHHHHHHHH VCFKAESAGNPILSQLGLNQSMGSMEGKEVRFGIAQSSLFTTVTTSFTTGTVNNMHDTLT HHHCCCCCCCHHHHHHCCCCCCCCCCCCCEEEEHHHHHHHHHHHHCCCCCCCCCHHHHHH PLGGLVPLLNMMLNVVFGGKGVGLMNMLMYAIIAVFLCGLMVGRTPEFLTKKIEGKEMKL HHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHCCCCHHHH IALLIILHPLLILMFSGLSVAIPAGLEGISNPGFHGLSQVLYEFASSAANNGSGFEGLGD HHHHHHHHHHHHHHHCCCCEECCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCC NTMFWNITTGVVMFFGRYVSIIVLLAISSLLASKKAVNESIGTLRTDNFTFTIVLVLVVL CCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEECCCHHHHHHHHHHHH IVGALTFFPALALGPISEHLVLWH HHHHHHHHHHHHHCCCCCCCEECC
PDB accession: NA
Resolution: NA
Structure class: Alpha
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 6.0
TargetDB status: NA
Availability: NA
References: 9226259; 11466286 [H]