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The map label for this gene is 126699097

Identifier: 126699097

GI number: 126699097

Start: 1729787

End: 1730395

Strand: Direct

Name: 126699097

Synonym: CD1493

Alternate gene names: NA

Gene position: 1729787-1730395 (Clockwise)

Preceding gene: 126699096

Following gene: 126699098

Centisome position: 40.32

GC content: 26.6

Gene sequence:

>609_bases
TTGGAAAAGGATTTTTTTAGAAAAAATGGAATTGATTTAGCCAAATCAATATTAGGTAAATATCTAATAAGGAAATATGA
AAATAAAGTAATTGTTACCAAAATCATAGAGACAGAAGCATACATGGGTGTAAATGATAAAGGAGCACATGTATATGGCA
ATAAGAAGACAGATAGAACTAAGCCATTATATTTAGATGGTGGACATATATATGTTTATTTAATTTATGGTATGTATAAT
TGCTTAAATTTATCTGCAAATATAGAAAATGTGCCAGAGTGTGTATTAATAAGAGGGGTAGAGCCGATAACTTCTTTAGA
TGAGATATCTATGAATAGATACAACAAAGCTTACACTGAGTTGAGTAAATATCAAGTAAAAAATATTACTAACGGACCAG
GAAAACTTTGCAAAGCTTTAAAAATAGATAGAAGTCTAAATAGTAAGAGTATAATGGGTGAAGAATTATATATAAGTGAT
TTTTATTATGATGATAAAGGAAAAAAAGTATTTAGTAAGGATGAGTTAGATATAAAAACTAGTAAACGTATAAATATAGA
TTATGCAGAAGAAGCAAAAGATTTTTTATGGCGTTTTTATATAGAATAA

Upstream 100 bases:

>100_bases
TAAATTTATTGTTTATATATATCACATTAATAAGAGTTAATTTTATTTATTACTTTAGTTGTATTTGATGCGTTTTAAAT
AAATTTTATGAGGTGAAATT

Downstream 100 bases:

>100_bases
GTTTTTATATAGGTAAGATATGTATCTATAGGAAGGTATTTTATAGGTATGTATCTTATTTTTTTATAGAATTTTTAGTT
TGATAAAAATAACTTTATAG

Product: 3-methyladenine DNA glycosylase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 202; Mature: 202

Protein sequence:

>202_residues
MEKDFFRKNGIDLAKSILGKYLIRKYENKVIVTKIIETEAYMGVNDKGAHVYGNKKTDRTKPLYLDGGHIYVYLIYGMYN
CLNLSANIENVPECVLIRGVEPITSLDEISMNRYNKAYTELSKYQVKNITNGPGKLCKALKIDRSLNSKSIMGEELYISD
FYYDDKGKKVFSKDELDIKTSKRINIDYAEEAKDFLWRFYIE

Sequences:

>Translated_202_residues
MEKDFFRKNGIDLAKSILGKYLIRKYENKVIVTKIIETEAYMGVNDKGAHVYGNKKTDRTKPLYLDGGHIYVYLIYGMYN
CLNLSANIENVPECVLIRGVEPITSLDEISMNRYNKAYTELSKYQVKNITNGPGKLCKALKIDRSLNSKSIMGEELYISD
FYYDDKGKKVFSKDELDIKTSKRINIDYAEEAKDFLWRFYIE
>Mature_202_residues
MEKDFFRKNGIDLAKSILGKYLIRKYENKVIVTKIIETEAYMGVNDKGAHVYGNKKTDRTKPLYLDGGHIYVYLIYGMYN
CLNLSANIENVPECVLIRGVEPITSLDEISMNRYNKAYTELSKYQVKNITNGPGKLCKALKIDRSLNSKSIMGEELYISD
FYYDDKGKKVFSKDELDIKTSKRINIDYAEEAKDFLWRFYIE

Specific function: Unknown

COG id: COG2094

COG function: function code L; 3-methyladenine DNA glycosylase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the DNA glycosylase MPG family

Homologues:

Organism=Homo sapiens, GI62632769, Length=154, Percent_Identity=34.4155844155844, Blast_Score=116, Evalue=1e-26,
Organism=Homo sapiens, GI62632765, Length=154, Percent_Identity=34.4155844155844, Blast_Score=116, Evalue=1e-26,
Organism=Homo sapiens, GI62632771, Length=154, Percent_Identity=34.4155844155844, Blast_Score=116, Evalue=2e-26,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): 3MGH_CLOD6 (Q18C13)

Other databases:

- EMBL:   AM180355
- RefSeq:   YP_001087994.1
- ProteinModelPortal:   Q18C13
- SMR:   Q18C13
- STRING:   Q18C13
- GeneID:   4916360
- GenomeReviews:   AM180355_GR
- KEGG:   cdf:CD1493
- NMPDR:   fig|1496.1.peg.3614
- eggNOG:   COG2094
- HOGENOM:   HBG664239
- OMA:   ACHARAG
- ProtClustDB:   CLSK2534905
- HAMAP:   MF_00527
- InterPro:   IPR011034
- InterPro:   IPR003180
- Gene3D:   G3DSA:3.10.300.10
- PANTHER:   PTHR10429
- TIGRFAMs:   TIGR00567

Pfam domain/function: PF02245 Pur_DNA_glyco; SSF50486 FMT_C_like

EC number: 3.2.2.-

Molecular weight: Translated: 23472; Mature: 23472

Theoretical pI: Translated: 8.87; Mature: 8.87

Prosite motif: PS00962 RIBOSOMAL_S2_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEKDFFRKNGIDLAKSILGKYLIRKYENKVIVTKIIETEAYMGVNDKGAHVYGNKKTDRT
CCCCHHHHCCHHHHHHHHHHHHHHHHCCCEEEEEEEEHHHHCCCCCCCCEEECCCCCCCC
KPLYLDGGHIYVYLIYGMYNCLNLSANIENVPECVLIRGVEPITSLDEISMNRYNKAYTE
CCEEEECCEEEEEEEHHHHHHHCCCCCCCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHH
LSKYQVKNITNGPGKLCKALKIDRSLNSKSIMGEELYISDFYYDDKGKKVFSKDELDIKT
HHHHHHCCCCCCHHHHHHHHHHCCCCCCCCCCCCEEEEEEEEECCCCCEECCCCCCCEEC
SKRINIDYAEEAKDFLWRFYIE
CCEECCCHHHHHHHHHHHEECC
>Mature Secondary Structure
MEKDFFRKNGIDLAKSILGKYLIRKYENKVIVTKIIETEAYMGVNDKGAHVYGNKKTDRT
CCCCHHHHCCHHHHHHHHHHHHHHHHCCCEEEEEEEEHHHHCCCCCCCCEEECCCCCCCC
KPLYLDGGHIYVYLIYGMYNCLNLSANIENVPECVLIRGVEPITSLDEISMNRYNKAYTE
CCEEEECCEEEEEEEHHHHHHHCCCCCCCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHH
LSKYQVKNITNGPGKLCKALKIDRSLNSKSIMGEELYISDFYYDDKGKKVFSKDELDIKT
HHHHHHCCCCCCHHHHHHHHHHCCCCCCCCCCCCEEEEEEEEECCCCCEECCCCCCCEEC
SKRINIDYAEEAKDFLWRFYIE
CCEECCCHHHHHHHHHHHEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA