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The map label for this gene is lrgB [H]

Identifier: 126699044

GI number: 126699044

Start: 1671041

End: 1671730

Strand: Direct

Name: lrgB [H]

Synonym: CD1440

Alternate gene names: 126699044

Gene position: 1671041-1671730 (Clockwise)

Preceding gene: 126699043

Following gene: 126699045

Centisome position: 38.95

GC content: 29.71

Gene sequence:

>690_bases
ATGTATAATGTATTACAGACACCAGTATTTGGTATAATAGTAACAATAGTTTTTTTCAATTTAGGAAGATACATTCAACG
AAAAACAAGTAATCCTATATGTAATCCTTTATTAATTGCAATCGTAGGAATAATATTGTTTTTAAGCATATCTAAAATCC
CTTATGAGAATTACAAGATAGGAGCTGATAGTCTAAATTTCTTTTTAGGTCCTGTCACAGTAGTACTTGCAGTTCCACTT
TATAAGCAATTTGAATTATTTAAAAAGCATATGTTTGAGATTATTGTAGGAATAGGTTGTGGTATAGTGATTTCTTTTGT
ATCTGTATTGATAATTGGCAAAATAGCTAATTCAGATGTAAGTATAATAAATTCACTAATTCCAAAATCTATAACAACAC
CAATGGGAATATCTTTAGCAAATTCTTTAAATGGTATAGAATCAATAACAGTTGTAGCCATAATTTTTACAGGTATTTTT
GGTGGTATGGTTGCTTCTACAGTATTCAAACTGGGGAATATAAATCATCCAGTTGCTAAAGGAATTGCTCTTGGAACATC
TGCACATGCTTTAGGAACTACAAAGGCTTTTGAACTGGGAGAAATAGAAGGAGCTATGAGTGGTGTTTCTATTGGAGTCT
CTGGTACAATTACAGTAATACTAATTCCAATTATAATGAATTTTATATAA

Upstream 100 bases:

>100_bases
GTGCTTTTATTAGTCATATGTTTAAGTACACTAATAGTAATGTATACTACTGGAATTATTGTGGAGAAAATGATAAAAAA
GAAGGAAGAAGGACAAAAAA

Downstream 100 bases:

>100_bases
AAAATAAAATTAAGATGAGTACCTTGAATACTTAAAACAAAATAAAATAAAAAAAATTTAAAATAAAAACTGAACGAAAA
AAATGCAAATAATGAAATAA

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 229; Mature: 229

Protein sequence:

>229_residues
MYNVLQTPVFGIIVTIVFFNLGRYIQRKTSNPICNPLLIAIVGIILFLSISKIPYENYKIGADSLNFFLGPVTVVLAVPL
YKQFELFKKHMFEIIVGIGCGIVISFVSVLIIGKIANSDVSIINSLIPKSITTPMGISLANSLNGIESITVVAIIFTGIF
GGMVASTVFKLGNINHPVAKGIALGTSAHALGTTKAFELGEIEGAMSGVSIGVSGTITVILIPIIMNFI

Sequences:

>Translated_229_residues
MYNVLQTPVFGIIVTIVFFNLGRYIQRKTSNPICNPLLIAIVGIILFLSISKIPYENYKIGADSLNFFLGPVTVVLAVPL
YKQFELFKKHMFEIIVGIGCGIVISFVSVLIIGKIANSDVSIINSLIPKSITTPMGISLANSLNGIESITVVAIIFTGIF
GGMVASTVFKLGNINHPVAKGIALGTSAHALGTTKAFELGEIEGAMSGVSIGVSGTITVILIPIIMNFI
>Mature_229_residues
MYNVLQTPVFGIIVTIVFFNLGRYIQRKTSNPICNPLLIAIVGIILFLSISKIPYENYKIGADSLNFFLGPVTVVLAVPL
YKQFELFKKHMFEIIVGIGCGIVISFVSVLIIGKIANSDVSIINSLIPKSITTPMGISLANSLNGIESITVVAIIFTGIF
GGMVASTVFKLGNINHPVAKGIALGTSAHALGTTKAFELGEIEGAMSGVSIGVSGTITVILIPIIMNFI

Specific function: Inhibits the expression or activity of extracellular murein hydrolases by interacting, possibly with LrgA, with the holin-like protein CidA. The LrgAB and CidA proteins may affect the proton motive force of the membrane. May be involved in programmed cell

COG id: COG1346

COG function: function code M; Putative effector of murein hydrolase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CidB/LrgB family. LrgB subfamily [H]

Homologues:

Organism=Escherichia coli, GI1788464, Length=220, Percent_Identity=34.0909090909091, Blast_Score=134, Evalue=4e-33,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR007300 [H]

Pfam domain/function: PF04172 LrgB [H]

EC number: NA

Molecular weight: Translated: 24332; Mature: 24332

Theoretical pI: Translated: 9.43; Mature: 9.43

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYNVLQTPVFGIIVTIVFFNLGRYIQRKTSNPICNPLLIAIVGIILFLSISKIPYENYKI
CCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCEE
GADSLNFFLGPVTVVLAVPLYKQFELFKKHMFEIIVGIGCGIVISFVSVLIIGKIANSDV
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHH
SIINSLIPKSITTPMGISLANSLNGIESITVVAIIFTGIFGGMVASTVFKLGNINHPVAK
HHHHHHHHHHCCCCCCHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHH
GIALGTSAHALGTTKAFELGEIEGAMSGVSIGVSGTITVILIPIIMNFI
HHHCCCCCHHHCCCCCHHHHHHHHHHCCCEECCCHHHHHHHHHHHHHHC
>Mature Secondary Structure
MYNVLQTPVFGIIVTIVFFNLGRYIQRKTSNPICNPLLIAIVGIILFLSISKIPYENYKI
CCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCEE
GADSLNFFLGPVTVVLAVPLYKQFELFKKHMFEIIVGIGCGIVISFVSVLIIGKIANSDV
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHH
SIINSLIPKSITTPMGISLANSLNGIESITVVAIIFTGIFGGMVASTVFKLGNINHPVAK
HHHHHHHHHHCCCCCCHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHH
GIALGTSAHALGTTKAFELGEIEGAMSGVSIGVSGTITVILIPIIMNFI
HHHCCCCCHHHCCCCCHHHHHHHHHHCCCEECCCHHHHHHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA