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The map label for this gene is fabD [H]

Identifier: 126698777

GI number: 126698777

Start: 1381338

End: 1382288

Strand: Direct

Name: fabD [H]

Synonym: CD1181

Alternate gene names: 126698777

Gene position: 1381338-1382288 (Clockwise)

Preceding gene: 126698776

Following gene: 126698778

Centisome position: 32.2

GC content: 31.97

Gene sequence:

>951_bases
ATGGGAAAAGTTGCATTAGTATTCCCTGGTCAAGGAGCTCAATATGTAGGTATGGCCAAGGATTTATATGAAAATAATGC
TGTTGCTAAAAGTGTAATAGATGAGGCTAGTGATGCCTTAAATATGGATTTAAAAAACCTTATGTTTAATGGAAATGAAG
AAGAACTTTCTAAAACTGAAAACACTCAACCTGCTATGGTTACACATAGTGTAGCTGTATTAAAAGCAGTACAAGCCCAA
GTAGATTTAAAATATAGTGCATGTTTAGGTTTATCTTTAGGAGAGTATAGTGCATTGGTTGCAGCAGATGCAATTGACTT
TAAAGATGCTGTATGCTTGGTCAAAAAAAGAGGTAAGTTTATGCAGGATACAGTTCCAACAGGTGTTGGAGCTATGGCAG
CAATTTTAGGTCTAGATAGAAGTATATTAGAAAATGTAGTTAAAGATATACAAGGAGGTATTGTGGAAGTAGCAAATTAT
AATTCTCCTGGTCAAATAGTTATATCTGGTGAAAATGAAAAGATAGAAGAAGCAATGGTGAAATGCAAAGAAGCAGGAGC
AAAAAGAGCTGTTAAATTAAATGTAAGTGGACCTTTTCACTCATCAATGCTAAGAGAAGCTGGAGTAAAATTAGGTAGTG
AGCTAGAAAAAGTCAACATAACTAAACCTAAAATTGATGTAGTAGCAAATGTAAATGCAGATTACTATAAAAGTGAAGGG
AAAGAACTGCTTATAAAACAAGTAAGTTCATCTGTTCTTTGGGAAGATTCTATAGAAAGACTTTTAAATGATGGATATGA
TACTTTTATAGAAATGGGACCTGGAAAAACTTTAAAAGCATTTATTAAGAAGATAGCTTCCAATAAAAAAGCAAATGTCA
ATATTTATAATATAGATGGTATAGATTCTCTTAATGAATTTGTACAAAATTATAGAAATGGAGAGATATAA

Upstream 100 bases:

>100_bases
GGTAAAAGAAATAACACCTTGTAAGGAAATTATAGAGGCTATGGTAAATCAAGCAAGAGAGATTATGCCAGCAATAGAAC
TGTAAATCAGGAGGAGCAAG

Downstream 100 bases:

>100_bases
TGATAAATCTTACAGGACAAGTAGCAGTTGTTACTGGTGGCTCTAGGGGTATAGGAAAAGAAATAGCAAAAAAACTAGCA
TCTTTTGGGGCTGATGTAGT

Product: malonyl CoA-acyl carrier protein transacylase

Products: NA

Alternate protein names: MCT [H]

Number of amino acids: Translated: 316; Mature: 315

Protein sequence:

>316_residues
MGKVALVFPGQGAQYVGMAKDLYENNAVAKSVIDEASDALNMDLKNLMFNGNEEELSKTENTQPAMVTHSVAVLKAVQAQ
VDLKYSACLGLSLGEYSALVAADAIDFKDAVCLVKKRGKFMQDTVPTGVGAMAAILGLDRSILENVVKDIQGGIVEVANY
NSPGQIVISGENEKIEEAMVKCKEAGAKRAVKLNVSGPFHSSMLREAGVKLGSELEKVNITKPKIDVVANVNADYYKSEG
KELLIKQVSSSVLWEDSIERLLNDGYDTFIEMGPGKTLKAFIKKIASNKKANVNIYNIDGIDSLNEFVQNYRNGEI

Sequences:

>Translated_316_residues
MGKVALVFPGQGAQYVGMAKDLYENNAVAKSVIDEASDALNMDLKNLMFNGNEEELSKTENTQPAMVTHSVAVLKAVQAQ
VDLKYSACLGLSLGEYSALVAADAIDFKDAVCLVKKRGKFMQDTVPTGVGAMAAILGLDRSILENVVKDIQGGIVEVANY
NSPGQIVISGENEKIEEAMVKCKEAGAKRAVKLNVSGPFHSSMLREAGVKLGSELEKVNITKPKIDVVANVNADYYKSEG
KELLIKQVSSSVLWEDSIERLLNDGYDTFIEMGPGKTLKAFIKKIASNKKANVNIYNIDGIDSLNEFVQNYRNGEI
>Mature_315_residues
GKVALVFPGQGAQYVGMAKDLYENNAVAKSVIDEASDALNMDLKNLMFNGNEEELSKTENTQPAMVTHSVAVLKAVQAQV
DLKYSACLGLSLGEYSALVAADAIDFKDAVCLVKKRGKFMQDTVPTGVGAMAAILGLDRSILENVVKDIQGGIVEVANYN
SPGQIVISGENEKIEEAMVKCKEAGAKRAVKLNVSGPFHSSMLREAGVKLGSELEKVNITKPKIDVVANVNADYYKSEGK
ELLIKQVSSSVLWEDSIERLLNDGYDTFIEMGPGKTLKAFIKKIASNKKANVNIYNIDGIDSLNEFVQNYRNGEI

Specific function: Fatty acid biosynthesis. [C]

COG id: COG0331

COG function: function code I; (acyl-carrier-protein) S-malonyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the fabD family [H]

Homologues:

Organism=Homo sapiens, GI51243059, Length=322, Percent_Identity=32.2981366459627, Blast_Score=144, Evalue=1e-34,
Organism=Escherichia coli, GI1787334, Length=296, Percent_Identity=44.2567567567568, Blast_Score=213, Evalue=9e-57,
Organism=Caenorhabditis elegans, GI71984332, Length=298, Percent_Identity=31.2080536912752, Blast_Score=122, Evalue=3e-28,
Organism=Caenorhabditis elegans, GI17550940, Length=292, Percent_Identity=27.7397260273973, Blast_Score=105, Evalue=3e-23,
Organism=Drosophila melanogaster, GI24665753, Length=311, Percent_Identity=32.7974276527331, Blast_Score=142, Evalue=2e-34,

Paralogues:

None

Copy number: 500 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001227
- InterPro:   IPR014043
- InterPro:   IPR016035
- InterPro:   IPR004410
- InterPro:   IPR016036 [H]

Pfam domain/function: PF00698 Acyl_transf_1 [H]

EC number: =2.3.1.39 [H]

Molecular weight: Translated: 34206; Mature: 34074

Theoretical pI: Translated: 5.00; Mature: 5.00

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGKVALVFPGQGAQYVGMAKDLYENNAVAKSVIDEASDALNMDLKNLMFNGNEEELSKTE
CCCEEEEECCCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHCCCHHHHHCCCCHHHHHHCC
NTQPAMVTHSVAVLKAVQAQVDLKYSACLGLSLGEYSALVAADAIDFKDAVCLVKKRGKF
CCCCHHHHHHHHHHHHHHHHHCCCHHHHHCCCHHHHHHHHHHHCCCHHHHHHHHHHCCCH
MQDTVPTGVGAMAAILGLDRSILENVVKDIQGGIVEVANYNSPGQIVISGENEKIEEAMV
HHHHCCCCHHHHHHHHHCCHHHHHHHHHHHCCCEEEEECCCCCCEEEEECCCHHHHHHHH
KCKEAGAKRAVKLNVSGPFHSSMLREAGVKLGSELEKVNITKPKIDVVANVNADYYKSEG
HHHHCCCCEEEEEECCCCHHHHHHHHHHHHHCCHHHHCCCCCCCEEEEEECCCHHHHCCC
KELLIKQVSSSVLWEDSIERLLNDGYDTFIEMGPGKTLKAFIKKIASNKKANVNIYNIDG
HHHHHHHHHHHHHHHHHHHHHHHCCCHHEEECCCCHHHHHHHHHHHCCCCCCEEEEECCC
IDSLNEFVQNYRNGEI
HHHHHHHHHHHCCCCC
>Mature Secondary Structure 
GKVALVFPGQGAQYVGMAKDLYENNAVAKSVIDEASDALNMDLKNLMFNGNEEELSKTE
CCEEEEECCCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHCCCHHHHHCCCCHHHHHHCC
NTQPAMVTHSVAVLKAVQAQVDLKYSACLGLSLGEYSALVAADAIDFKDAVCLVKKRGKF
CCCCHHHHHHHHHHHHHHHHHCCCHHHHHCCCHHHHHHHHHHHCCCHHHHHHHHHHCCCH
MQDTVPTGVGAMAAILGLDRSILENVVKDIQGGIVEVANYNSPGQIVISGENEKIEEAMV
HHHHCCCCHHHHHHHHHCCHHHHHHHHHHHCCCEEEEECCCCCCEEEEECCCHHHHHHHH
KCKEAGAKRAVKLNVSGPFHSSMLREAGVKLGSELEKVNITKPKIDVVANVNADYYKSEG
HHHHCCCCEEEEEECCCCHHHHHHHHHHHHHCCHHHHCCCCCCCEEEEEECCCHHHHCCC
KELLIKQVSSSVLWEDSIERLLNDGYDTFIEMGPGKTLKAFIKKIASNKKANVNIYNIDG
HHHHHHHHHHHHHHHHHHHHHHHCCCHHEEECCCCHHHHHHHHHHHCCCCCCEEEEECCC
IDSLNEFVQNYRNGEI
HHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8759840; 9534248; 9384377 [H]