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The map label for this gene is lytT [H]

Identifier: 126698676

GI number: 126698676

Start: 1282293

End: 1283006

Strand: Direct

Name: lytT [H]

Synonym: CD1089

Alternate gene names: 126698676

Gene position: 1282293-1283006 (Clockwise)

Preceding gene: 126698675

Following gene: 126698687

Centisome position: 29.89

GC content: 23.95

Gene sequence:

>714_bases
ATGATTAAGATAGCAGTTTGTGAAGATGAAAAAGAAACACAACTTTTAATAGAAGATTACCTTGAGAATATATTAAAAGA
TATAAGTATAGAATATGAGATACAAAAGTATATATCTGGAGAAGAGTTACTGGAAAGTAATTTAAAAGATATAGATATAT
TACTTCTTGATATAAAAATGGAAAAACTAAATGGAATGGATACTGCAAGAAAGATTAGAGAAGTAGACAATGAAATGGAA
ATAATATTTGTAACTTCATTAATAGATTATGTGCAAGAAGGTTATGAGGTAAGAGCTTATAGGTATTTACTAAAGCCAAT
AGAGTTGGAAGAACTAAAAAAACATGTGCTAACTTGTATCAAAGATATTGAAATAAATAAGGAAAGTCATATTACAATAA
AAAATAAGTCTAATACATATAAGATTTATTTAAATGAAATAAAATATATAGAAGTTCAAAAAAAAGATATGCTAATACAC
ACAATAAACAAGAATTTTGATATAAAATATAGTTTAGGCAAAATAGAAAAAGAATTAAATCCATATAAATTTATAAGATG
CCATAAAAGTTTTATAGTAAATTTAAGATATGTTGAAAATATAAAGCCTAATACTGCAATACTGGAAAGTGGAGAAGAGG
TACCTATTAGTAGATATAGATATAAAGAAGTTAAGGAGAAATTCTTAAAATTTCTTGGTGATACAATATGCTAA

Upstream 100 bases:

>100_bases
TGAAAATGTTATCCTAAAGTATCAGATATACAAAATTATCTTTAAATATATTATAAATATTTTAATTGTATTAACTAGAA
ATTATGTAAGGAGGCATTTT

Downstream 100 bases:

>100_bases
ACTTTATGACTGAGCTATTAGTAGTTTTATCTATATTTATACAGTTTTCTATAATGAACGGAATTTTAATTTATAAAAAG
GATAGTAAAAAAAATGAAAA

Product: two-component response regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 237; Mature: 237

Protein sequence:

>237_residues
MIKIAVCEDEKETQLLIEDYLENILKDISIEYEIQKYISGEELLESNLKDIDILLLDIKMEKLNGMDTARKIREVDNEME
IIFVTSLIDYVQEGYEVRAYRYLLKPIELEELKKHVLTCIKDIEINKESHITIKNKSNTYKIYLNEIKYIEVQKKDMLIH
TINKNFDIKYSLGKIEKELNPYKFIRCHKSFIVNLRYVENIKPNTAILESGEEVPISRYRYKEVKEKFLKFLGDTIC

Sequences:

>Translated_237_residues
MIKIAVCEDEKETQLLIEDYLENILKDISIEYEIQKYISGEELLESNLKDIDILLLDIKMEKLNGMDTARKIREVDNEME
IIFVTSLIDYVQEGYEVRAYRYLLKPIELEELKKHVLTCIKDIEINKESHITIKNKSNTYKIYLNEIKYIEVQKKDMLIH
TINKNFDIKYSLGKIEKELNPYKFIRCHKSFIVNLRYVENIKPNTAILESGEEVPISRYRYKEVKEKFLKFLGDTIC
>Mature_237_residues
MIKIAVCEDEKETQLLIEDYLENILKDISIEYEIQKYISGEELLESNLKDIDILLLDIKMEKLNGMDTARKIREVDNEME
IIFVTSLIDYVQEGYEVRAYRYLLKPIELEELKKHVLTCIKDIEINKESHITIKNKSNTYKIYLNEIKYIEVQKKDMLIH
TINKNFDIKYSLGKIEKELNPYKFIRCHKSFIVNLRYVENIKPNTAILESGEEVPISRYRYKEVKEKFLKFLGDTIC

Specific function: Member of the two-component regulatory system lytS/lytT that probably regulates genes involved in cell wall metabolism [H]

COG id: COG3279

COG function: function code KT; Response regulator of the LytR/AlgR family

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1788724, Length=194, Percent_Identity=25.7731958762887, Blast_Score=80, Evalue=8e-17,
Organism=Escherichia coli, GI87082052, Length=243, Percent_Identity=24.2798353909465, Blast_Score=65, Evalue=6e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR007492
- InterPro:   IPR001789 [H]

Pfam domain/function: PF04397 LytTR; PF00072 Response_reg [H]

EC number: NA

Molecular weight: Translated: 28232; Mature: 28232

Theoretical pI: Translated: 5.32; Mature: 5.32

Prosite motif: PS50110 RESPONSE_REGULATORY ; PS50930 HTH_LYTTR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIKIAVCEDEKETQLLIEDYLENILKDISIEYEIQKYISGEELLESNLKDIDILLLDIKM
CEEEEEECCCCHHHHHHHHHHHHHHHHCCCHHHHHHHCCHHHHHHCCCCCEEEEEEEEEH
EKLNGMDTARKIREVDNEMEIIFVTSLIDYVQEGYEVRAYRYLLKPIELEELKKHVLTCI
HHHCCCHHHHHHHHCCCCEEEEEHHHHHHHHHCCHHHHHHHHHHCCCCHHHHHHHHHHHH
KDIEINKESHITIKNKSNTYKIYLNEIKYIEVQKKDMLIHTINKNFDIKYSLGKIEKELN
HHCCCCCCCEEEEECCCCEEEEEEECEEEEEEECCCEEEEEECCCCEEEEEHHHHHHHCC
PYKFIRCHKSFIVNLRYVENIKPNTAILESGEEVPISRYRYKEVKEKFLKFLGDTIC
HHHHHHHHHHHHEEEHHHCCCCCCHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MIKIAVCEDEKETQLLIEDYLENILKDISIEYEIQKYISGEELLESNLKDIDILLLDIKM
CEEEEEECCCCHHHHHHHHHHHHHHHHCCCHHHHHHHCCHHHHHHCCCCCEEEEEEEEEH
EKLNGMDTARKIREVDNEMEIIFVTSLIDYVQEGYEVRAYRYLLKPIELEELKKHVLTCI
HHHCCCHHHHHHHHCCCCEEEEEHHHHHHHHHCCHHHHHHHHHHCCCCHHHHHHHHHHHH
KDIEINKESHITIKNKSNTYKIYLNEIKYIEVQKKDMLIHTINKNFDIKYSLGKIEKELN
HHCCCCCCCEEEEECCCCEEEEEEECEEEEEEECCCEEEEEECCCCEEEEEHHHHHHHCC
PYKFIRCHKSFIVNLRYVENIKPNTAILESGEEVPISRYRYKEVKEKFLKFLGDTIC
HHHHHHHHHHHHEEEHHHCCCCCCHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8969504; 9384377 [H]