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The map label for this gene is dinB

Identifier: 126698476

GI number: 126698476

Start: 1082006

End: 1083103

Strand: Direct

Name: dinB

Synonym: CD0899

Alternate gene names: 126698476

Gene position: 1082006-1083103 (Clockwise)

Preceding gene: 126698475

Following gene: 126698477

Centisome position: 25.22

GC content: 29.33

Gene sequence:

>1098_bases
ATGAAACATTATAGAAAAATAATTCATATAGATATGGACGCTTTTTATGCATCTATAGAACAAAGAGATAATAAAAAATT
AAAAGGAAGACCTGTTATTGTCGGTGGAAATCCACAAAGCCGAGGTGTGGTTGCAACGTGTTCTTATGAAGCTAGAAAAT
TTGGTATCCATTCAGCTATGCCATCAGCTGTAGCTTACAATAGGTGTCCATATGCAGTTTTTGTAAGACCTAGATTTGAT
GTTTATAAGAGTGTGTCAGAGAAAATAAGAGATATATTTTATAGATACACGGATTTAGTTGAACCATTATCTTTAGATGA
AGCTTATTTAGATGTAACAAAAAATAAAAAAAATATTGATTCATCAATTGAGATAGCAAAGCAAATAAAAAAAGATATAT
TTAGAGAAGTTGGTCTTACTTCTTCAGCTGGTGTGTCATACAATAAGTTTCTTGCTAAGATTGCATCAGACTTAAGAAAG
CCAAATGGGTTAACTGTAATAACCGAAGAAAATGCCCAGGACTTTTTAGATAAATTACCTGTGAATAAATTTTTTGGTGT
TGGAAAAGTTACTTCAAATACTCTTAAAAATTTAGGTATAAAAACTGGATATGATTTAAGGTGTTTAAATTTATTTGAAC
TTGAAAATATATTCAAAAAAAGAGGTTATGAATTATATAAATTTGCTAGAGGAATAGACGATAGACCAGTGGAACCAAAT
AGGGTTAGAAAATCTGTTGGGGCTGAGACTACATTAAGTCATAATTTGGATATTGATGAAGAAGAAACACGCAACATTCT
TGATGAACTTTGTGAAGAAGTATGTCATAGATTAAAAAACTCTGAGAAGTTTGGAAAAACATTAACATTAAAAATTAAAT
ATGAGGACTTTACAAAGATAACTAGAAGCCTTAGTTTAGAACACTATATTGACGAATATAATGATATAAGAAGTGGTGTA
GATAATTTGTTGAGAAATGTTGAGGTTAATGGAAAACAAATTAGGCTATTGGGAGTTACAATATCAAACTTAAGTGATAA
AAAAGAAACTTATAAAGATATTACATTATTTGAATACATGGATAGTATCCAAATGTGA

Upstream 100 bases:

>100_bases
AGAAAATAATGAAAAAATACCAAAAAGAAACATAAGTTTGGTATAATTAAAAAGTAATATAAATAAAATTAATCTATTTA
TACTTTAAAAGGTGATAATA

Downstream 100 bases:

>100_bases
GTTTTGTTTAAATGAAATAACACTAGCTTTAATACTATATAATTGAGGCTAGTGTTATTTTATGAATATTTTTATATTTT
TTGTTTTTTGACATTATATA

Product: DNA polymerase IV

Products: NA

Alternate protein names: Pol IV

Number of amino acids: Translated: 365; Mature: 365

Protein sequence:

>365_residues
MKHYRKIIHIDMDAFYASIEQRDNKKLKGRPVIVGGNPQSRGVVATCSYEARKFGIHSAMPSAVAYNRCPYAVFVRPRFD
VYKSVSEKIRDIFYRYTDLVEPLSLDEAYLDVTKNKKNIDSSIEIAKQIKKDIFREVGLTSSAGVSYNKFLAKIASDLRK
PNGLTVITEENAQDFLDKLPVNKFFGVGKVTSNTLKNLGIKTGYDLRCLNLFELENIFKKRGYELYKFARGIDDRPVEPN
RVRKSVGAETTLSHNLDIDEEETRNILDELCEEVCHRLKNSEKFGKTLTLKIKYEDFTKITRSLSLEHYIDEYNDIRSGV
DNLLRNVEVNGKQIRLLGVTISNLSDKKETYKDITLFEYMDSIQM

Sequences:

>Translated_365_residues
MKHYRKIIHIDMDAFYASIEQRDNKKLKGRPVIVGGNPQSRGVVATCSYEARKFGIHSAMPSAVAYNRCPYAVFVRPRFD
VYKSVSEKIRDIFYRYTDLVEPLSLDEAYLDVTKNKKNIDSSIEIAKQIKKDIFREVGLTSSAGVSYNKFLAKIASDLRK
PNGLTVITEENAQDFLDKLPVNKFFGVGKVTSNTLKNLGIKTGYDLRCLNLFELENIFKKRGYELYKFARGIDDRPVEPN
RVRKSVGAETTLSHNLDIDEEETRNILDELCEEVCHRLKNSEKFGKTLTLKIKYEDFTKITRSLSLEHYIDEYNDIRSGV
DNLLRNVEVNGKQIRLLGVTISNLSDKKETYKDITLFEYMDSIQM
>Mature_365_residues
MKHYRKIIHIDMDAFYASIEQRDNKKLKGRPVIVGGNPQSRGVVATCSYEARKFGIHSAMPSAVAYNRCPYAVFVRPRFD
VYKSVSEKIRDIFYRYTDLVEPLSLDEAYLDVTKNKKNIDSSIEIAKQIKKDIFREVGLTSSAGVSYNKFLAKIASDLRK
PNGLTVITEENAQDFLDKLPVNKFFGVGKVTSNTLKNLGIKTGYDLRCLNLFELENIFKKRGYELYKFARGIDDRPVEPN
RVRKSVGAETTLSHNLDIDEEETRNILDELCEEVCHRLKNSEKFGKTLTLKIKYEDFTKITRSLSLEHYIDEYNDIRSGV
DNLLRNVEVNGKQIRLLGVTISNLSDKKETYKDITLFEYMDSIQM

Specific function: Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits

COG id: COG0389

COG function: function code L; Nucleotidyltransferase/DNA polymerase involved in DNA repair

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 umuC domain

Homologues:

Organism=Homo sapiens, GI84043967, Length=414, Percent_Identity=29.2270531400966, Blast_Score=158, Evalue=7e-39,
Organism=Homo sapiens, GI7706681, Length=415, Percent_Identity=29.1566265060241, Blast_Score=158, Evalue=9e-39,
Organism=Homo sapiens, GI154350220, Length=326, Percent_Identity=27.9141104294479, Blast_Score=117, Evalue=1e-26,
Organism=Homo sapiens, GI7705344, Length=109, Percent_Identity=45.8715596330275, Blast_Score=113, Evalue=3e-25,
Organism=Homo sapiens, GI5729982, Length=414, Percent_Identity=22.9468599033816, Blast_Score=102, Evalue=4e-22,
Organism=Escherichia coli, GI1786425, Length=349, Percent_Identity=41.2607449856734, Blast_Score=258, Evalue=6e-70,
Organism=Escherichia coli, GI1787432, Length=205, Percent_Identity=28.2926829268293, Blast_Score=81, Evalue=9e-17,
Organism=Caenorhabditis elegans, GI193205700, Length=429, Percent_Identity=32.4009324009324, Blast_Score=163, Evalue=1e-40,
Organism=Caenorhabditis elegans, GI193205702, Length=374, Percent_Identity=31.283422459893, Blast_Score=117, Evalue=9e-27,
Organism=Caenorhabditis elegans, GI17537959, Length=254, Percent_Identity=28.3464566929134, Blast_Score=96, Evalue=2e-20,
Organism=Caenorhabditis elegans, GI115534089, Length=122, Percent_Identity=38.5245901639344, Blast_Score=70, Evalue=2e-12,
Organism=Saccharomyces cerevisiae, GI6324921, Length=213, Percent_Identity=25.8215962441315, Blast_Score=66, Evalue=8e-12,
Organism=Drosophila melanogaster, GI19923006, Length=420, Percent_Identity=28.3333333333333, Blast_Score=145, Evalue=4e-35,
Organism=Drosophila melanogaster, GI21355641, Length=316, Percent_Identity=29.4303797468354, Blast_Score=115, Evalue=6e-26,
Organism=Drosophila melanogaster, GI24644984, Length=316, Percent_Identity=29.4303797468354, Blast_Score=115, Evalue=6e-26,
Organism=Drosophila melanogaster, GI24668444, Length=158, Percent_Identity=31.6455696202532, Blast_Score=72, Evalue=6e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): DPO4_CLOD6 (Q18A91)

Other databases:

- EMBL:   AM180355
- RefSeq:   YP_001087373.1
- ProteinModelPortal:   Q18A91
- SMR:   Q18A91
- STRING:   Q18A91
- GeneID:   4914151
- GenomeReviews:   AM180355_GR
- KEGG:   cdf:CD0899
- NMPDR:   fig|1496.1.peg.1745
- eggNOG:   COG0389
- HOGENOM:   HBG734504
- OMA:   VICAASY
- ProtClustDB:   CLSK631013
- GO:   GO:0005737
- HAMAP:   MF_01113
- InterPro:   IPR017962
- InterPro:   IPR017961
- InterPro:   IPR001126
- InterPro:   IPR017963
- InterPro:   IPR022880
- Gene3D:   G3DSA:3.30.1490.100
- PANTHER:   PTHR11076

Pfam domain/function: PF00817 IMS; SSF100879 DNA_pol_Y-fam_little_finger

EC number: =2.7.7.7

Molecular weight: Translated: 42010; Mature: 42010

Theoretical pI: Translated: 9.09; Mature: 9.09

Prosite motif: PS50173 UMUC

Important sites: ACT_SITE 107-107

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKHYRKIIHIDMDAFYASIEQRDNKKLKGRPVIVGGNPQSRGVVATCSYEARKFGIHSAM
CCCHHEEEEEEHHHHHHHHHHHCCCCCCCCEEEECCCCCCCCEEEEECCHHHHHCHHHCC
PSAVAYNRCPYAVFVRPRFDVYKSVSEKIRDIFYRYTDLVEPLSLDEAYLDVTKNKKNID
CHHHHHCCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHCCCCCCH
SSIEIAKQIKKDIFREVGLTSSAGVSYNKFLAKIASDLRKPNGLTVITEENAQDFLDKLP
HHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHCCCCCEEEEECCCHHHHHHHCC
VNKFFGVGKVTSNTLKNLGIKTGYDLRCLNLFELENIFKKRGYELYKFARGIDDRPVEPN
HHHHHCCCCHHHHHHHHCCCCCCCCEEEHHHHHHHHHHHHCCHHHHHHHCCCCCCCCCHH
RVRKSVGAETTLSHNLDIDEEETRNILDELCEEVCHRLKNSEKFGKTLTLKIKYEDFTKI
HHHHHCCCCCEECCCCCCCHHHHHHHHHHHHHHHHHHHHCCHHCCCEEEEEEEHHHHHHH
TRSLSLEHYIDEYNDIRSGVDNLLRNVEVNGKQIRLLGVTISNLSDKKETYKDITLFEYM
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEEEECCCCHHHHHHHHHHHHHHH
DSIQM
HHHCC
>Mature Secondary Structure
MKHYRKIIHIDMDAFYASIEQRDNKKLKGRPVIVGGNPQSRGVVATCSYEARKFGIHSAM
CCCHHEEEEEEHHHHHHHHHHHCCCCCCCCEEEECCCCCCCCEEEEECCHHHHHCHHHCC
PSAVAYNRCPYAVFVRPRFDVYKSVSEKIRDIFYRYTDLVEPLSLDEAYLDVTKNKKNID
CHHHHHCCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHCCCCCCH
SSIEIAKQIKKDIFREVGLTSSAGVSYNKFLAKIASDLRKPNGLTVITEENAQDFLDKLP
HHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHCCCCCEEEEECCCHHHHHHHCC
VNKFFGVGKVTSNTLKNLGIKTGYDLRCLNLFELENIFKKRGYELYKFARGIDDRPVEPN
HHHHHCCCCHHHHHHHHCCCCCCCCEEEHHHHHHHHHHHHCCHHHHHHHCCCCCCCCCHH
RVRKSVGAETTLSHNLDIDEEETRNILDELCEEVCHRLKNSEKFGKTLTLKIKYEDFTKI
HHHHHCCCCCEECCCCCCCHHHHHHHHHHHHHHHHHHHHCCHHCCCEEEEEEEHHHHHHH
TRSLSLEHYIDEYNDIRSGVDNLLRNVEVNGKQIRLLGVTISNLSDKKETYKDITLFEYM
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEEEECCCCHHHHHHHHHHHHHHH
DSIQM
HHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA