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The map label for this gene is glgC

Identifier: 126698459

GI number: 126698459

Start: 1060468

End: 1061628

Strand: Direct

Name: glgC

Synonym: CD0882

Alternate gene names: 126698459

Gene position: 1060468-1061628 (Clockwise)

Preceding gene: 126698458

Following gene: 126698460

Centisome position: 24.72

GC content: 31.01

Gene sequence:

>1161_bases
ATGAAAAAAGAGATGTTAGCTATGATTTTGGCAGGAGGGCAAGGTTCAAGATTAGGTGTTTTTACAAAAAGAATTGCCAA
ACCAGCTGTATCATTTGGAGGTAAGTATAGAATTATAGATTTTGTGTTAAGCAATTGTTCAAACTCTGGTATTGATACTG
TAGGTGTTTTAACTCAATATAGACCGTTGATATTAAATTCACATATAGGCATGGGAAGTCATTGGGATTTGGACAGAATA
AATGGTGGTGTCTATGTTTTACAACCATTTATGAATGAAAAAGAAGGAAATTGGTATAATGGTACAGCACATGCGATATA
TCAAAATATGGACTTTGTAGATACCTATAATCCAGAATATGTATTGATATTATCTGGTGACCATATATACAAGATGGATT
ATAGCAAAATGTTAAAATTTCATAAGGAAAAAGGCTCTAAAGCTACAATAGCAGTGATTGAAGTTCCTTGGGATGAAGCT
TCAAGATTTGGGATAATGAATACAAATGAAGATTCAAGTATCTATGAATTTGAAGAAAAACCAAGTGAACCTAAGAGCAA
TTTGGCATCTATGGGAGTATACATATTTGATTGGAAAATGTTGAGAAATTATTTTAAGGAAGCAGAAAAAAATCCAGAAA
TAAATTATGATGATTTTGGAAAAAATTTAATACCTAAAATGTTAGAAGATAATGTTGGAATGTATGCTTATCCATTTAAA
GGATACTGGAGAGATGTAGGAACTATACAAAGTCTATGGGATGCTAATATGGATATAATAAAATCTCCAGAAACACTTGA
TTTAGCAGACCCTAAGTGGAAGATATATACAAATACTATGGCAATGCCTCCACAATATATAGGTAAAAATGCAAATGTTC
ATAGATCAATGATAGCTGATGGTTGTAGAATTTTAGGTGAAGTAGGTAACTCTGTATTATCACATGGAGTTGTTGTTGGT
AAAGGAAGTAAAGTAATTGATTCAGTAATAATGCCAAATGTTGTAATAGGTGAAAATGTAACTATAGAAAAAGCTATGAT
AGGTGAGTGTGCAACTATAAATGATAATGTTCAGATAAAGAATGTAAATAATGAAATAAATGTAGTTTCTGAGTATGAAA
ATATCGAACCTAGATGCGTATTAATAGAAGGAGGTCTTTAA

Upstream 100 bases:

>100_bases
TTAAGCAACATTTATACACGACATTTATTGACTGATAAAGTTTATAAAAGTAAAAATGCAATTATAAATATTAATTACTA
GATGAGGGGAGTGTCATTAA

Downstream 100 bases:

>100_bases
GATGAGAAATGAATGTTTAGGGATAATAAATTTAAACAAAAAAGGAGACCCAGCAATAAACAAACTTAACTATGGAAGAC
CAATAGCATCTACACCAATA

Product: glucose-1-phosphate adenylyltransferase

Products: NA

Alternate protein names: ADP-glucose pyrophosphorylase; ADPGlc PPase; ADP-glucose synthase

Number of amino acids: Translated: 386; Mature: 386

Protein sequence:

>386_residues
MKKEMLAMILAGGQGSRLGVFTKRIAKPAVSFGGKYRIIDFVLSNCSNSGIDTVGVLTQYRPLILNSHIGMGSHWDLDRI
NGGVYVLQPFMNEKEGNWYNGTAHAIYQNMDFVDTYNPEYVLILSGDHIYKMDYSKMLKFHKEKGSKATIAVIEVPWDEA
SRFGIMNTNEDSSIYEFEEKPSEPKSNLASMGVYIFDWKMLRNYFKEAEKNPEINYDDFGKNLIPKMLEDNVGMYAYPFK
GYWRDVGTIQSLWDANMDIIKSPETLDLADPKWKIYTNTMAMPPQYIGKNANVHRSMIADGCRILGEVGNSVLSHGVVVG
KGSKVIDSVIMPNVVIGENVTIEKAMIGECATINDNVQIKNVNNEINVVSEYENIEPRCVLIEGGL

Sequences:

>Translated_386_residues
MKKEMLAMILAGGQGSRLGVFTKRIAKPAVSFGGKYRIIDFVLSNCSNSGIDTVGVLTQYRPLILNSHIGMGSHWDLDRI
NGGVYVLQPFMNEKEGNWYNGTAHAIYQNMDFVDTYNPEYVLILSGDHIYKMDYSKMLKFHKEKGSKATIAVIEVPWDEA
SRFGIMNTNEDSSIYEFEEKPSEPKSNLASMGVYIFDWKMLRNYFKEAEKNPEINYDDFGKNLIPKMLEDNVGMYAYPFK
GYWRDVGTIQSLWDANMDIIKSPETLDLADPKWKIYTNTMAMPPQYIGKNANVHRSMIADGCRILGEVGNSVLSHGVVVG
KGSKVIDSVIMPNVVIGENVTIEKAMIGECATINDNVQIKNVNNEINVVSEYENIEPRCVLIEGGL
>Mature_386_residues
MKKEMLAMILAGGQGSRLGVFTKRIAKPAVSFGGKYRIIDFVLSNCSNSGIDTVGVLTQYRPLILNSHIGMGSHWDLDRI
NGGVYVLQPFMNEKEGNWYNGTAHAIYQNMDFVDTYNPEYVLILSGDHIYKMDYSKMLKFHKEKGSKATIAVIEVPWDEA
SRFGIMNTNEDSSIYEFEEKPSEPKSNLASMGVYIFDWKMLRNYFKEAEKNPEINYDDFGKNLIPKMLEDNVGMYAYPFK
GYWRDVGTIQSLWDANMDIIKSPETLDLADPKWKIYTNTMAMPPQYIGKNANVHRSMIADGCRILGEVGNSVLSHGVVVG
KGSKVIDSVIMPNVVIGENVTIEKAMIGECATINDNVQIKNVNNEINVVSEYENIEPRCVLIEGGL

Specific function: Glycogen biosynthesis; first step. [C]

COG id: COG0448

COG function: function code G; ADP-glucose pyrophosphorylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family

Homologues:

Organism=Homo sapiens, GI11761621, Length=359, Percent_Identity=26.1838440111421, Blast_Score=87, Evalue=2e-17,
Organism=Homo sapiens, GI11761619, Length=351, Percent_Identity=25.0712250712251, Blast_Score=84, Evalue=2e-16,
Organism=Escherichia coli, GI1789837, Length=378, Percent_Identity=41.5343915343915, Blast_Score=280, Evalue=1e-76,
Organism=Escherichia coli, GI1788351, Length=256, Percent_Identity=28.515625, Blast_Score=68, Evalue=9e-13,
Organism=Caenorhabditis elegans, GI133931050, Length=366, Percent_Identity=28.6885245901639, Blast_Score=94, Evalue=8e-20,
Organism=Saccharomyces cerevisiae, GI6320148, Length=361, Percent_Identity=24.3767313019391, Blast_Score=87, Evalue=5e-18,
Organism=Drosophila melanogaster, GI21355443, Length=363, Percent_Identity=25.068870523416, Blast_Score=87, Evalue=2e-17,
Organism=Drosophila melanogaster, GI24644084, Length=363, Percent_Identity=25.068870523416, Blast_Score=87, Evalue=2e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): GLGC_CLOD6 (Q18A75)

Other databases:

- EMBL:   AM180355
- RefSeq:   YP_001087356.1
- ProteinModelPortal:   Q18A75
- SMR:   Q18A75
- STRING:   Q18A75
- GeneID:   4913417
- GenomeReviews:   AM180355_GR
- KEGG:   cdf:CD0882
- NMPDR:   fig|1496.1.peg.1762
- eggNOG:   COG0448
- HOGENOM:   HBG703946
- OMA:   GTVDAYW
- ProtClustDB:   CLSK2534635
- HAMAP:   MF_00624
- InterPro:   IPR005836
- InterPro:   IPR011831
- InterPro:   IPR023049
- InterPro:   IPR005835
- InterPro:   IPR011004
- TIGRFAMs:   TIGR02091

Pfam domain/function: PF00483 NTP_transferase; SSF51161 Trimer_LpxA_like

EC number: =2.7.7.27

Molecular weight: Translated: 43412; Mature: 43412

Theoretical pI: Translated: 5.30; Mature: 5.30

Prosite motif: PS00808 ADP_GLC_PYROPHOSPH_1; PS00809 ADP_GLC_PYROPHOSPH_2; PS00810 ADP_GLC_PYROPHOSPH_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
4.9 %Met     (Translated Protein)
6.0 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
4.9 %Met     (Mature Protein)
6.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKEMLAMILAGGQGSRLGVFTKRIAKPAVSFGGKYRIIDFVLSNCSNSGIDTVGVLTQY
CCHHEEEEEEECCCCCEEHHHHHHHHHHHHHCCCCEEEHHHHHHCCCCCCCCHHHHHHHC
RPLILNSHIGMGSHWDLDRINGGVYVLQPFMNEKEGNWYNGTAHAIYQNMDFVDTYNPEY
CCEEEECCCCCCCCCCHHHCCCCEEEEECCCCCCCCCEECCCHHEEEECCCEEECCCCCE
VLILSGDHIYKMDYSKMLKFHKEKGSKATIAVIEVPWDEASRFGIMNTNEDSSIYEFEEK
EEEECCCEEEECCHHHHHHHHHCCCCEEEEEEEEECCCCHHCCCCEECCCCCCEEECCCC
PSEPKSNLASMGVYIFDWKMLRNYFKEAEKNPEINYDDFGKNLIPKMLEDNVGMYAYPFK
CCCCHHHHHHCCEEEEEHHHHHHHHHHHHCCCCCCHHHCCHHHHHHHHHCCCCEEEECCC
GYWRDVGTIQSLWDANMDIIKSPETLDLADPKWKIYTNTMAMPPQYIGKNANVHRSMIAD
HHHHHHHHHHHHHCCCCCEECCCCCCCCCCCCEEEEECCCCCCHHHHCCCCCHHHHHHHH
GCRILGEVGNSVLSHGVVVGKGSKVIDSVIMPNVVIGENVTIEKAMIGECATINDNVQIK
HHHHHHHHHHHHHHCCEEEECCHHHHHHHHCCCEEECCCCEEEHHHCCCCEEECCCEEEE
NVNNEINVVSEYENIEPRCVLIEGGL
ECCCCEEEEECCCCCCCEEEEEECCC
>Mature Secondary Structure
MKKEMLAMILAGGQGSRLGVFTKRIAKPAVSFGGKYRIIDFVLSNCSNSGIDTVGVLTQY
CCHHEEEEEEECCCCCEEHHHHHHHHHHHHHCCCCEEEHHHHHHCCCCCCCCHHHHHHHC
RPLILNSHIGMGSHWDLDRINGGVYVLQPFMNEKEGNWYNGTAHAIYQNMDFVDTYNPEY
CCEEEECCCCCCCCCCHHHCCCCEEEEECCCCCCCCCEECCCHHEEEECCCEEECCCCCE
VLILSGDHIYKMDYSKMLKFHKEKGSKATIAVIEVPWDEASRFGIMNTNEDSSIYEFEEK
EEEECCCEEEECCHHHHHHHHHCCCCEEEEEEEEECCCCHHCCCCEECCCCCCEEECCCC
PSEPKSNLASMGVYIFDWKMLRNYFKEAEKNPEINYDDFGKNLIPKMLEDNVGMYAYPFK
CCCCHHHHHHCCEEEEEHHHHHHHHHHHHCCCCCCHHHCCHHHHHHHHHCCCCEEEECCC
GYWRDVGTIQSLWDANMDIIKSPETLDLADPKWKIYTNTMAMPPQYIGKNANVHRSMIAD
HHHHHHHHHHHHHCCCCCEECCCCCCCCCCCCEEEEECCCCCCHHHHCCCCCHHHHHHHH
GCRILGEVGNSVLSHGVVVGKGSKVIDSVIMPNVVIGENVTIEKAMIGECATINDNVQIK
HHHHHHHHHHHHHHCCEEEECCHHHHHHHHCCCEEECCCCEEEHHHCCCCEEECCCEEEE
NVNNEINVVSEYENIEPRCVLIEGGL
ECCCCEEEEECCCCCCCEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA