Click here to switch to the map view.

The map label for this gene is infC [H]

Identifier: 126698264

GI number: 126698264

Start: 831229

End: 831738

Strand: Direct

Name: infC [H]

Synonym: CD0685

Alternate gene names: 126698264

Gene position: 831229-831738 (Clockwise)

Preceding gene: 126698262

Following gene: 126698265

Centisome position: 19.37

GC content: 31.37

Gene sequence:

>510_bases
ATTAGCAAAGAATTAGCAATCAATGAACAAATAAAAGATAAGGAAATAAGAGTCCTTTCACCAACAGGTGAACAACTTGG
AGTAATGCCTACTAAAGAAGCTCAAGCAATGGCTAATAGCAAAAACTTAGATTTGGTTCAAATCTCGCCGAATGCAAATC
CACCAGTATGTAAGATAATGGATTATGGAAAGTTTAGATATGAGCAAGCGAGAAAAGAGAAAGAAGCTAAGAAAAAACAA
AAAACTATAGTTGTAAAAGAAGTAAGACTTAGACCAGGTATTGAACAAAATGATTTAAATACGAAAGCTAATAATGCTAT
AAAGTTCCTTAAAAAAGGGGATAAAGTCAAAGTTGAACTTAGATTTAGAGGAAGAGAATTAGGACATAAAGACATAGGTA
AAGAAGTTATGCTTAAGTTTTTAGATATAATAAAAGAGTTTGGAGAACCAACAAAAGCCCCTGCATTTGAGGGTAATAAT
ATGGTTGTAATTATAGATCCAAAAAAATAG

Upstream 100 bases:

>100_bases
GCTTAATTTTAATTTAAGTTTGTTTAAATTTGGTAACTTATATTGCGGATGATTACGTCATCCGCTTTTTATTTTATAAA
AATTTTGGAGGTGTCCTACA

Downstream 100 bases:

>100_bases
ATGATTAACTGAGAGGAGGAATTTGTCATGCCTAAAATGAAAACTCATAGAGGTGCAGCAAAGAGATTAAAGAAAACAGG
AACTGGAAAGTTAAAGAGAG

Product: translation initiation factor IF-3

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 169; Mature: 168

Protein sequence:

>169_residues
MSKELAINEQIKDKEIRVLSPTGEQLGVMPTKEAQAMANSKNLDLVQISPNANPPVCKIMDYGKFRYEQARKEKEAKKKQ
KTIVVKEVRLRPGIEQNDLNTKANNAIKFLKKGDKVKVELRFRGRELGHKDIGKEVMLKFLDIIKEFGEPTKAPAFEGNN
MVVIIDPKK

Sequences:

>Translated_169_residues
MSKELAINEQIKDKEIRVLSPTGEQLGVMPTKEAQAMANSKNLDLVQISPNANPPVCKIMDYGKFRYEQARKEKEAKKKQ
KTIVVKEVRLRPGIEQNDLNTKANNAIKFLKKGDKVKVELRFRGRELGHKDIGKEVMLKFLDIIKEFGEPTKAPAFEGNN
MVVIIDPKK
>Mature_168_residues
SKELAINEQIKDKEIRVLSPTGEQLGVMPTKEAQAMANSKNLDLVQISPNANPPVCKIMDYGKFRYEQARKEKEAKKKQK
TIVVKEVRLRPGIEQNDLNTKANNAIKFLKKGDKVKVELRFRGRELGHKDIGKEVMLKFLDIIKEFGEPTKAPAFEGNNM
VVIIDPKK

Specific function: IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins [H]

COG id: COG0290

COG function: function code J; Translation initiation factor 3 (IF-3)

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the IF-3 family [H]

Homologues:

Organism=Escherichia coli, GI1788012, Length=164, Percent_Identity=47.5609756097561, Blast_Score=144, Evalue=3e-36,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR019813
- InterPro:   IPR001288
- InterPro:   IPR019815
- InterPro:   IPR019814 [H]

Pfam domain/function: PF00707 IF3_C; PF05198 IF3_N [H]

EC number: NA

Molecular weight: Translated: 19203; Mature: 19072

Theoretical pI: Translated: 10.40; Mature: 10.40

Prosite motif: PS00938 IF3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSKELAINEQIKDKEIRVLSPTGEQLGVMPTKEAQAMANSKNLDLVQISPNANPPVCKIM
CCCCCCCCCCCCCCEEEEECCCCCCCCCCCCHHHHHHCCCCCCEEEEECCCCCCCEEEEE
DYGKFRYEQARKEKEAKKKQKTIVVKEVRLRPGIEQNDLNTKANNAIKFLKKGDKVKVEL
CCCHHHHHHHHHHHHHHHHHHHEEEEEHHCCCCCCCCCCCCCHHHHHHHHHCCCEEEEEE
RFRGRELGHKDIGKEVMLKFLDIIKEFGEPTKAPAFEGNNMVVIIDPKK
EECCCCCCHHHCCHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEEECCC
>Mature Secondary Structure 
SKELAINEQIKDKEIRVLSPTGEQLGVMPTKEAQAMANSKNLDLVQISPNANPPVCKIM
CCCCCCCCCCCCCEEEEECCCCCCCCCCCCHHHHHHCCCCCCEEEEECCCCCCCEEEEE
DYGKFRYEQARKEKEAKKKQKTIVVKEVRLRPGIEQNDLNTKANNAIKFLKKGDKVKVEL
CCCHHHHHHHHHHHHHHHHHHHEEEEEHHCCCCCCCCCCCCCHHHHHHHHHCCCEEEEEE
RFRGRELGHKDIGKEVMLKFLDIIKEFGEPTKAPAFEGNNMVVIIDPKK
EECCCCCCHHHCCHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11997336 [H]