| Definition | Clostridium difficile 630 chromosome, complete genome. |
|---|---|
| Accession | NC_009089 |
| Length | 4,290,252 |
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The map label for this gene is yvkC [H]
Identifier: 126698160
GI number: 126698160
Start: 695634
End: 698207
Strand: Direct
Name: yvkC [H]
Synonym: CD0582
Alternate gene names: 126698160
Gene position: 695634-698207 (Clockwise)
Preceding gene: 126698159
Following gene: 126698163
Centisome position: 16.21
GC content: 40.17
Gene sequence:
>2574_bases ATGATTATGATTTATTATGTCTTGCCACTGGAACATAAACAAGCAACCATTGAAATTGTTGGTGGAAAAGGGATGTCTTT ATCAAAACTATTGACAGCAGGCATCCCTGTGCCAGACGGTTTTCATGTTACGACTGCTTCATACCAGATTTTTGTTGAGA CGAACCATATTCAGTCTCGAATTAATAAACTGCTAGATGGTATTGATTCCAATAATACCAGCCAACTTGAAGATGTATCT AAGAAAATAGGGGAGCTTTTCCATAATGGAGAAATGCCACAGGAAGTGTCGGACGCAATTAAAATGGCTTATGCTGGATT AGGGAACATATCGGTGGCTGTCCGTTCGTCTGCGACTGCTGAAGATTTACCTGACGCTTCTTTTGCAGGTCAGCAGGAAA CTTATCTTAACATACAAGGTGAAGATAAAGTTATTGACTCTGTAAAGAGATGCTGGGCTTCCTTATGGACAGCTCGTGCT ATTGCTTATCGTGTGAAGAATAATATAAAGCACGAGATTGTCGCACTTGCTGTTGTAGTACAAAAGCTTGCATTTTCCGA TTCATCTGGTATTATGTTTACGTTAAACCCAATCAATGGTAGACGTAGCGAAATGATTATTAACGCTGCATGGGGGCTTG GTGAAGCGGTGGTTTCTAGCTTAGTTACACCCGATACAATCGTAGTGGATAAGGACTCCGAACGAATTATATCGTATGAA GTGGCAAATAAAGAGATTATGACGGTTCGTACTTCAGAAGGAACAGAAGAAACCATGGTTCCTGAAAGGTTGAGAAAAAA ATATGCTCTTACTCGTAATCAGGTAATGCAACTGATACAGCTTGGAAAGAAAATTGAGAAGTATTATCAAATGCCTATGG ATGTAGAGTGGGCACTGGAAAAAGATAAATTGTACATTGTTCAGGCTCGTCCAATTACTGTTCTGCCACCAGAATGGGTA TTGCCAGAACAGGATGTTGTATACACAAAGGGAAGTTTGGCAGAACATTTGCCAAATCCTGTTACACCTTTGTTCGCCAC ACTTGGTCTTGAAATCGTAAACCGTGCATCAGAGCTTTTATGGATAGATATGTTTGGTAAAAGTGCGAAAAAATTATTAC CAAAAAACGGGGCATATACGGTTATTAATGGATATGTTTATCTTTCTGCTAAATCAAAGCCACTTTTGATTGCTATCAAA TCCCTTTCCCCACGCTCTTTACGTAGGACACTTATGAACAGCGTTGCACGCTGGGAAACGGCACGAAAAGGATATGAGGA TGCTATTAAACAATGGGAAGAAAAGCCCCTGCATACTATGAACGCCCATCAAATTATGGAGGGTATTCAGACAATATTTT ATGCCGCATGTATTTATTTCACAAGGATTCAGCTTACATTGCCTGCTGCTTCTATCAGTGAAACATTATTTACAAAATTA TTTCAAGGAGCAGTTCGACGTGCTGGTATAACGGATACTTCCGTTTTCCTGCTTGGGTTTGATACGATTGTTCTGCAATC GGAAAAGGAGTTGTGGGGTATTTCAGAATGGGTAAAGCAAAATAACAGCATCAACCTTTATCTGCAAAACAGTCCTGCAA TAAAGATAGCAGAAGATTTCATGTCTTCAGTTGTGCCTGTTGGAGTTTCACAGGAAGTATGGATAGAATGGAAAAATCGA ATCAATAAGTACTTTAAAGAGTTTGGTCGTACCGCTTATGAGTTTGATTTTGCGCATTCCACACCGCAGGAAACACTTAC ACCAACTTTTGAATCCGTAAAAACATTTGTGGAAGGAAAAGGGGAAAGTCCTTTTTTACGCCAGACCACGTTTGAAAAGC GTAGAAAACATGCAGAAGAAGAGATTTTACAACACATAGGTGGATTGCGTAAAAAACTATTTTTTAAGTTGCTCCATTGG GCACAGGAAACCTCTCCTATGCGTGAAAATGCTATTTATTTGATGGGAATGGGACATCCTCTGATTCGTTGTATGTTTCA GGAAATCTCAGAACGATTCATACGAGGAGGAGCTATTTCACATTTAGATGATATTTATTGGCTCACAAAATCGGAATTGG AGGTACTTATAGAGCAGTTGGATAAAAACAAGTCTCTATCTGATATGAACGGGATAATACCTGTTCGAAAAGCTGAACTT AAAAAATACATGGGTTATATGTCACCATCCAAGTTGCCAGAGAAAAACAAAAAAACTATATCACAAGCACAACAGAAGCA GAAAGATGGGAAAATTGTGTTGACGGGCATTGGTACCAGTACTGGTGTTGTGACGGCTCCAGCTTGTGTACTGAATAGTC CAGCAGATTTTGAAAGCTTTCAACCTGGAAGTGTTTTGGTTGCAGTTACCACAACTCCAGCATGGACACCATTATTTTCA TCTGCAAGTGCGATTGTAACGGACATTGGTGGTCCTCTTAGCCATTCAAGCATTGTCGCACGTGAATATGGCATCCCAGC CGTTATGGCTACACACATTGCCACACGAACTATTAAGAGCGGACAAATGATAACGGTGGACGGGTTGGCAGGTACGGTGA CGTTTGATGAGTAA
Upstream 100 bases:
>100_bases TATCAATCAGCTACACGTCACGACCATTGGATAGTTCGGAAAAAATGTTGGATGAAACAATGAATATATTTCTGAACGGA ATTATGAATGATGGAGGTGA
Downstream 100 bases:
>100_bases AAAGCCTATTTTCGCTTTGAAGCTTTCGACCTTTGTGATTGCGTTAGCGGAAGTAGTAATACTTAAAGTTTTCAGATTTC ATAATACTACTAATACCCAC
Product: PEP-utilizing kinase
Products: AMP; phosphoenolpyruvate; phosphate
Alternate protein names: NA
Number of amino acids: Translated: 857; Mature: 857
Protein sequence:
>857_residues MIMIYYVLPLEHKQATIEIVGGKGMSLSKLLTAGIPVPDGFHVTTASYQIFVETNHIQSRINKLLDGIDSNNTSQLEDVS KKIGELFHNGEMPQEVSDAIKMAYAGLGNISVAVRSSATAEDLPDASFAGQQETYLNIQGEDKVIDSVKRCWASLWTARA IAYRVKNNIKHEIVALAVVVQKLAFSDSSGIMFTLNPINGRRSEMIINAAWGLGEAVVSSLVTPDTIVVDKDSERIISYE VANKEIMTVRTSEGTEETMVPERLRKKYALTRNQVMQLIQLGKKIEKYYQMPMDVEWALEKDKLYIVQARPITVLPPEWV LPEQDVVYTKGSLAEHLPNPVTPLFATLGLEIVNRASELLWIDMFGKSAKKLLPKNGAYTVINGYVYLSAKSKPLLIAIK SLSPRSLRRTLMNSVARWETARKGYEDAIKQWEEKPLHTMNAHQIMEGIQTIFYAACIYFTRIQLTLPAASISETLFTKL FQGAVRRAGITDTSVFLLGFDTIVLQSEKELWGISEWVKQNNSINLYLQNSPAIKIAEDFMSSVVPVGVSQEVWIEWKNR INKYFKEFGRTAYEFDFAHSTPQETLTPTFESVKTFVEGKGESPFLRQTTFEKRRKHAEEEILQHIGGLRKKLFFKLLHW AQETSPMRENAIYLMGMGHPLIRCMFQEISERFIRGGAISHLDDIYWLTKSELEVLIEQLDKNKSLSDMNGIIPVRKAEL KKYMGYMSPSKLPEKNKKTISQAQQKQKDGKIVLTGIGTSTGVVTAPACVLNSPADFESFQPGSVLVAVTTTPAWTPLFS SASAIVTDIGGPLSHSSIVAREYGIPAVMATHIATRTIKSGQMITVDGLAGTVTFDE
Sequences:
>Translated_857_residues MIMIYYVLPLEHKQATIEIVGGKGMSLSKLLTAGIPVPDGFHVTTASYQIFVETNHIQSRINKLLDGIDSNNTSQLEDVS KKIGELFHNGEMPQEVSDAIKMAYAGLGNISVAVRSSATAEDLPDASFAGQQETYLNIQGEDKVIDSVKRCWASLWTARA IAYRVKNNIKHEIVALAVVVQKLAFSDSSGIMFTLNPINGRRSEMIINAAWGLGEAVVSSLVTPDTIVVDKDSERIISYE VANKEIMTVRTSEGTEETMVPERLRKKYALTRNQVMQLIQLGKKIEKYYQMPMDVEWALEKDKLYIVQARPITVLPPEWV LPEQDVVYTKGSLAEHLPNPVTPLFATLGLEIVNRASELLWIDMFGKSAKKLLPKNGAYTVINGYVYLSAKSKPLLIAIK SLSPRSLRRTLMNSVARWETARKGYEDAIKQWEEKPLHTMNAHQIMEGIQTIFYAACIYFTRIQLTLPAASISETLFTKL FQGAVRRAGITDTSVFLLGFDTIVLQSEKELWGISEWVKQNNSINLYLQNSPAIKIAEDFMSSVVPVGVSQEVWIEWKNR INKYFKEFGRTAYEFDFAHSTPQETLTPTFESVKTFVEGKGESPFLRQTTFEKRRKHAEEEILQHIGGLRKKLFFKLLHW AQETSPMRENAIYLMGMGHPLIRCMFQEISERFIRGGAISHLDDIYWLTKSELEVLIEQLDKNKSLSDMNGIIPVRKAEL KKYMGYMSPSKLPEKNKKTISQAQQKQKDGKIVLTGIGTSTGVVTAPACVLNSPADFESFQPGSVLVAVTTTPAWTPLFS SASAIVTDIGGPLSHSSIVAREYGIPAVMATHIATRTIKSGQMITVDGLAGTVTFDE >Mature_857_residues MIMIYYVLPLEHKQATIEIVGGKGMSLSKLLTAGIPVPDGFHVTTASYQIFVETNHIQSRINKLLDGIDSNNTSQLEDVS KKIGELFHNGEMPQEVSDAIKMAYAGLGNISVAVRSSATAEDLPDASFAGQQETYLNIQGEDKVIDSVKRCWASLWTARA IAYRVKNNIKHEIVALAVVVQKLAFSDSSGIMFTLNPINGRRSEMIINAAWGLGEAVVSSLVTPDTIVVDKDSERIISYE VANKEIMTVRTSEGTEETMVPERLRKKYALTRNQVMQLIQLGKKIEKYYQMPMDVEWALEKDKLYIVQARPITVLPPEWV LPEQDVVYTKGSLAEHLPNPVTPLFATLGLEIVNRASELLWIDMFGKSAKKLLPKNGAYTVINGYVYLSAKSKPLLIAIK SLSPRSLRRTLMNSVARWETARKGYEDAIKQWEEKPLHTMNAHQIMEGIQTIFYAACIYFTRIQLTLPAASISETLFTKL FQGAVRRAGITDTSVFLLGFDTIVLQSEKELWGISEWVKQNNSINLYLQNSPAIKIAEDFMSSVVPVGVSQEVWIEWKNR INKYFKEFGRTAYEFDFAHSTPQETLTPTFESVKTFVEGKGESPFLRQTTFEKRRKHAEEEILQHIGGLRKKLFFKLLHW AQETSPMRENAIYLMGMGHPLIRCMFQEISERFIRGGAISHLDDIYWLTKSELEVLIEQLDKNKSLSDMNGIIPVRKAEL KKYMGYMSPSKLPEKNKKTISQAQQKQKDGKIVLTGIGTSTGVVTAPACVLNSPADFESFQPGSVLVAVTTTPAWTPLFS SASAIVTDIGGPLSHSSIVAREYGIPAVMATHIATRTIKSGQMITVDGLAGTVTFDE
Specific function: ESSENTIAL STEP IN GLUCONEOGENESIS WHEN PYRUVATE AND LACTATE ARE USED AS A CARBON SOURCE. [C]
COG id: COG0574
COG function: function code G; Phosphoenolpyruvate synthase/pyruvate phosphate dikinase
Gene ontology:
Cell location: Cytoplasm [C]
Metaboloic importance: Non_Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Belongs to the PEP-utilizing enzyme family [H]
Homologues:
Organism=Escherichia coli, GI1787994, Length=339, Percent_Identity=39.5280235988201, Blast_Score=214, Evalue=1e-56, Organism=Caenorhabditis elegans, GI17564524, Length=354, Percent_Identity=31.638418079096, Blast_Score=142, Evalue=7e-34,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR013815 - InterPro: IPR013816 - InterPro: IPR008279 - InterPro: IPR002192 [H]
Pfam domain/function: PF00391 PEP-utilizers; PF01326 PPDK_N [H]
EC number: 2.7.9.2
Molecular weight: Translated: 95802; Mature: 95802
Theoretical pI: Translated: 8.25; Mature: 8.25
Prosite motif: NA
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.5 %Cys (Translated Protein) 3.0 %Met (Translated Protein) 3.5 %Cys+Met (Translated Protein) 0.5 %Cys (Mature Protein) 3.0 %Met (Mature Protein) 3.5 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MIMIYYVLPLEHKQATIEIVGGKGMSLSKLLTAGIPVPDGFHVTTASYQIFVETNHIQSR CEEEEEEEEECCCCEEEEEECCCCCCHHHHHHCCCCCCCCCEEEEEEEEEEEECHHHHHH INKLLDGIDSNNTSQLEDVSKKIGELFHNGEMPQEVSDAIKMAYAGLGNISVAVRSSATA HHHHHCCCCCCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCEEEEEECCCCH EDLPDASFAGQQETYLNIQGEDKVIDSVKRCWASLWTARAIAYRVKNNIKHEIVALAVVV HCCCCCCCCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHH QKLAFSDSSGIMFTLNPINGRRSEMIINAAWGLGEAVVSSLVTPDTIVVDKDSERIISYE HHHHCCCCCCEEEEEECCCCCCCEEEEEECCCHHHHHHHHHCCCCEEEEECCCCCEEEEE VANKEIMTVRTSEGTEETMVPERLRKKYALTRNQVMQLIQLGKKIEKYYQMPMDVEWALE ECCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEC KDKLYIVQARPITVLPPEWVLPEQDVVYTKGSLAEHLPNPVTPLFATLGLEIVNRASELL CCCEEEEEECCEEECCCCCCCCCCCEEEECCCHHHHCCCCCHHHHHHHHHHHHHHHHHEE WIDMFGKSAKKLLPKNGAYTVINGYVYLSAKSKPLLIAIKSLSPRSLRRTLMNSVARWET EEEHHCCHHHHHCCCCCCEEEEEEEEEEEECCCCEEEEEECCCHHHHHHHHHHHHHHHHH ARKGYEDAIKQWEEKPLHTMNAHQIMEGIQTIFYAACIYFTRIQLTLPAASISETLFTKL HHCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHEEEEECHHHHHHHHHHHH FQGAVRRAGITDTSVFLLGFDTIVLQSEKELWGISEWVKQNNSINLYLQNSPAIKIAEDF HHHHHHHCCCCCCEEEEEEEEEEEEECCHHHCCHHHHHHCCCCEEEEECCCCCEEHHHHH MSSVVPVGVSQEVWIEWKNRINKYFKEFGRTAYEFDFAHSTPQETLTPTFESVKTFVEGK HHHHCCCCCCHHHHHHHHHHHHHHHHHHCCEEEEEECCCCCCHHHCCCCHHHHHHHHCCC GESPFLRQTTFEKRRKHAEEEILQHIGGLRKKLFFKLLHWAQETSPMRENAIYLMGMGHP CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHCCEEEEECCCH LIRCMFQEISERFIRGGAISHLDDIYWLTKSELEVLIEQLDKNKSLSDMNGIIPVRKAEL HHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHCCCCCCHHHHH KKYMGYMSPSKLPEKNKKTISQAQQKQKDGKIVLTGIGTSTGVVTAPACVLNSPADFESF HHHHCCCCCCCCCCCHHHHHHHHHHHCCCCCEEEEECCCCCCCEECCHHHCCCCCCCCCC QPGSVLVAVTTTPAWTPLFSSASAIVTDIGGPLSHSSIVAREYGIPAVMATHIATRTIKS CCCCEEEEEECCCCCCHHHCCCHHHHHHCCCCCCCCHHHHHHCCCCHHHHHHHHHHHCCC GQMITVDGLAGTVTFDE CCEEEEECCEEEEEECC >Mature Secondary Structure MIMIYYVLPLEHKQATIEIVGGKGMSLSKLLTAGIPVPDGFHVTTASYQIFVETNHIQSR CEEEEEEEEECCCCEEEEEECCCCCCHHHHHHCCCCCCCCCEEEEEEEEEEEECHHHHHH INKLLDGIDSNNTSQLEDVSKKIGELFHNGEMPQEVSDAIKMAYAGLGNISVAVRSSATA HHHHHCCCCCCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCEEEEEECCCCH EDLPDASFAGQQETYLNIQGEDKVIDSVKRCWASLWTARAIAYRVKNNIKHEIVALAVVV HCCCCCCCCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHH QKLAFSDSSGIMFTLNPINGRRSEMIINAAWGLGEAVVSSLVTPDTIVVDKDSERIISYE HHHHCCCCCCEEEEEECCCCCCCEEEEEECCCHHHHHHHHHCCCCEEEEECCCCCEEEEE VANKEIMTVRTSEGTEETMVPERLRKKYALTRNQVMQLIQLGKKIEKYYQMPMDVEWALE ECCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEC KDKLYIVQARPITVLPPEWVLPEQDVVYTKGSLAEHLPNPVTPLFATLGLEIVNRASELL CCCEEEEEECCEEECCCCCCCCCCCEEEECCCHHHHCCCCCHHHHHHHHHHHHHHHHHEE WIDMFGKSAKKLLPKNGAYTVINGYVYLSAKSKPLLIAIKSLSPRSLRRTLMNSVARWET EEEHHCCHHHHHCCCCCCEEEEEEEEEEEECCCCEEEEEECCCHHHHHHHHHHHHHHHHH ARKGYEDAIKQWEEKPLHTMNAHQIMEGIQTIFYAACIYFTRIQLTLPAASISETLFTKL HHCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHEEEEECHHHHHHHHHHHH FQGAVRRAGITDTSVFLLGFDTIVLQSEKELWGISEWVKQNNSINLYLQNSPAIKIAEDF HHHHHHHCCCCCCEEEEEEEEEEEEECCHHHCCHHHHHHCCCCEEEEECCCCCEEHHHHH MSSVVPVGVSQEVWIEWKNRINKYFKEFGRTAYEFDFAHSTPQETLTPTFESVKTFVEGK HHHHCCCCCCHHHHHHHHHHHHHHHHHHCCEEEEEECCCCCCHHHCCCCHHHHHHHHCCC GESPFLRQTTFEKRRKHAEEEILQHIGGLRKKLFFKLLHWAQETSPMRENAIYLMGMGHP CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHCCEEEEECCCH LIRCMFQEISERFIRGGAISHLDDIYWLTKSELEVLIEQLDKNKSLSDMNGIIPVRKAEL HHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHCCCCCCHHHHH KKYMGYMSPSKLPEKNKKTISQAQQKQKDGKIVLTGIGTSTGVVTAPACVLNSPADFESF HHHHCCCCCCCCCCCHHHHHHHHHHHCCCCCEEEEECCCCCCCEECCHHHCCCCCCCCCC QPGSVLVAVTTTPAWTPLFSSASAIVTDIGGPLSHSSIVAREYGIPAVMATHIATRTIKS CCCCEEEEEECCCCCCHHHCCCHHHHHHCCCCCCCCHHHHHHCCCCHHHHHHHHHHHCCC GQMITVDGLAGTVTFDE CCEEEEECCEEEEEECC
PDB accession: NA
Resolution: NA
Structure class: Alpha Beta
Cofactors: NA
Metal ions: Mg2+; Mn2+ [C]
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): 10.5 {phosphate}} 0.083 {pyruvate}} 0.028 {ATP}} [C]
Substrates: ATP; pyruvate; H2O
Specific reaction: ATP + pyruvate + H2O = AMP + phosphoenolpyruvate + phosphate
General reaction: Phospho group transfer [C]
Inhibitor: 2-Oxoglutarate; 3-Phosphoglyceraldehyde; 5'-Adenylyl methylen ediphosphonate; ADP; ADP glucose; AMP; ATP; Ca2+; F-; Iodoacetate; Malate; Mg2+; Mn2+; Oxalacetate; PCMB; Phosphoenolpyruvate; Sulfhydryl reagents [C]
Structure determination priority: 9.0
TargetDB status: NA
Availability: NA
References: 9384377 [H]