| Definition | Clostridium difficile 630 chromosome, complete genome. |
|---|---|
| Accession | NC_009089 |
| Length | 4,290,252 |
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The map label for this gene is cheA [H]
Identifier: 126698118
GI number: 126698118
Start: 643952
End: 646054
Strand: Direct
Name: cheA [H]
Synonym: CD0539
Alternate gene names: 126698118
Gene position: 643952-646054 (Clockwise)
Preceding gene: 126698117
Following gene: 126698119
Centisome position: 15.01
GC content: 28.67
Gene sequence:
>2103_bases ATGAGACAAATGTTAGATATGTTTATATTTGAGACAAGTTTATTACTCGAACAATTAGATGAAATTATGATTCAAATAGA AAAAGAGAAAGTATTTACTCATAACAACATTAATGAAACTTTTAGAATAATGCATACGATAAAAGGTTCAGCATCTATGA TGGGGTTAGACAATATATCTGCTTTAGCACATAGTGTAGAAGACTTGTTTTATGCTATACGTGAAGGTAAAATAGAAGTT TTAGACAATGACCTATTATTTGATTTAGTCTTTCAATCATTAGATTTTATAAGAAGAGATATAGATGAGTTACAATCAAG AGGTTGTATATCTTCTGATTACTCTAATTTTATTGAAGGAATTGAAGAGTATGTGAGTACTTTGGAATTATCAAGTTCTA TGAAATCAAAGGATAATGCAAATTTAGAAAGTAAAGACGAAAAAGAAGTAATCGATTCAAATTTTGAATACAAAGAAGAC TCTGATGTAGTAAAAATAATCTTTGAACAAGGTTGCATGATGGAAAATGTGAGAGCTTTCATGCTTGTATTTGAACTTAG AGATTACTGTGAATTTATAGATTTTTATCCAAAAGATGTAGAAACAAATGCAGAGTCTACAGAGTATATTAAAAGTTATG GGTTTTATATACAATTTGTAGCTAAAGAGGATAAGGCAATAGTTTATAAAACTATAGAAGATAATCTCTATGTAAAAGAA TACATAAATATTAGTAAAAAAGAAATAGAAATGAAAAGTACATCAAACAATGATGCAGTAGAAAATAAATTAAAAGATAA TAATAAAGTAAGTAAAAGTTATCAAAATAACTATACAGAAGATGAGATACAAGAAGATGTTTTAAATGAAAAAACTGATA TGGAAAAAGATAGTCTAAGTGAAGAAAATGAACATTTACCAATAAGTAAGCAGAGTATTATGAGTGTAAATTTAGAAAAA TTGGACTTACTTCAAAATATAGTTGGAGAAATTGTAATTATGGAATCAATGGTTGTAAATAGCGTAAATTCTACAGGTGT TGATATAGATAATTTCAATAAGGCAACAAGACAATTACACAAGCTTACAGATGAATTGCAAGATATAGTAATGTCTATGC GTATGATTCAAATTGCTGGTGTATTTCAAAAAATGCATAGAATTGTACGAGATATGAATAAAAAATTAGATAAAAATGTA GAGTTAATAACTATAGGAGCAGAGACAGAGGTAGATAAGAGTGTAATTGATAATTTAGCAGAACCTTTTATGCACCTTAT AAGAAATGCTATGGACCATGCAATAGAGCCTATTGAGGAGCGTATAGCGAAAGGTAAAGAAGAAGTGGGAAAGATAGTTT TATCTGCTGAAAATCTAGGCGGAGAAGCTGTGATAAGTATTTCAGATGATGGTAGAGGCATTATGAGAGATAAGATTTTG GCAAAAGCTAAGGAACAAGGTCTTCTTAAACATCAAAGTAATGAGTATACTGATGACGAGGTCAATTCTTTGATTATGAC TCCAGGCTTTTCTACAAAAGAATCTATAACTGAATTTTCTGGAAGAGGAGTAGGCATGGACATTGTTCGTAAAAGTATTG AAAAAGTTGGAGGTTCAATTGAAGTAAAAAGTAAACAGGATGAAGGGACAACCTTTACTATAAAAATACCATTAACTCTT TCTATAGTAGAGGGTATGAAGTTTAAAGTTGGAGATTCACTATTTACTTTACCAATATCATCTATAAGAAGAACATTTAA ACTTACAGACTTAAATCAAATAATTACAGAAGGAAATAAGACAGAGTTAATTACAATATATGGAGCCTGTATTCCCATTA TAAGGTTACATAAAATATATAATATTCAAACAAAAGTAACCAATCTGATGAATGGGAATATGATAATTATTGAAAATGAG CATAAAGCAGTATGCATTTTTGTTGATGAAATAATAGGTAATCAGCAAGTTGTTGTGAAACCATTTCCAGTTTATTTTAA CCGATTTAATATAAAAAATAAGGGTTTATCGGGATGTACAATACTTGGGGATGGAAGTATAAGTTTAATTATAGATGCAG ATAGCATTATAGAAATATATTAG
Upstream 100 bases:
>100_bases AGATAAGAGAATCATCAAGGATTTAAATTATGAGATGCATATATAATAGAAAATTATTTGTAGGTCGTAGGTGATAAATG TGAATTATATTGAACCGAGT
Downstream 100 bases:
>100_bases GGGATTTAAAGTATGGCTAAAGATGAAATTATTAAACAAGTGTTAACATTTTATGTCAATGATGTTATTTATGGAATAGA ATTAGAAAATGTGATTGAAA
Product: chemotaxis protein
Products: NA
Alternate protein names: NA
Number of amino acids: Translated: 700; Mature: 700
Protein sequence:
>700_residues MRQMLDMFIFETSLLLEQLDEIMIQIEKEKVFTHNNINETFRIMHTIKGSASMMGLDNISALAHSVEDLFYAIREGKIEV LDNDLLFDLVFQSLDFIRRDIDELQSRGCISSDYSNFIEGIEEYVSTLELSSSMKSKDNANLESKDEKEVIDSNFEYKED SDVVKIIFEQGCMMENVRAFMLVFELRDYCEFIDFYPKDVETNAESTEYIKSYGFYIQFVAKEDKAIVYKTIEDNLYVKE YINISKKEIEMKSTSNNDAVENKLKDNNKVSKSYQNNYTEDEIQEDVLNEKTDMEKDSLSEENEHLPISKQSIMSVNLEK LDLLQNIVGEIVIMESMVVNSVNSTGVDIDNFNKATRQLHKLTDELQDIVMSMRMIQIAGVFQKMHRIVRDMNKKLDKNV ELITIGAETEVDKSVIDNLAEPFMHLIRNAMDHAIEPIEERIAKGKEEVGKIVLSAENLGGEAVISISDDGRGIMRDKIL AKAKEQGLLKHQSNEYTDDEVNSLIMTPGFSTKESITEFSGRGVGMDIVRKSIEKVGGSIEVKSKQDEGTTFTIKIPLTL SIVEGMKFKVGDSLFTLPISSIRRTFKLTDLNQIITEGNKTELITIYGACIPIIRLHKIYNIQTKVTNLMNGNMIIIENE HKAVCIFVDEIIGNQQVVVKPFPVYFNRFNIKNKGLSGCTILGDGSISLIIDADSIIEIY
Sequences:
>Translated_700_residues MRQMLDMFIFETSLLLEQLDEIMIQIEKEKVFTHNNINETFRIMHTIKGSASMMGLDNISALAHSVEDLFYAIREGKIEV LDNDLLFDLVFQSLDFIRRDIDELQSRGCISSDYSNFIEGIEEYVSTLELSSSMKSKDNANLESKDEKEVIDSNFEYKED SDVVKIIFEQGCMMENVRAFMLVFELRDYCEFIDFYPKDVETNAESTEYIKSYGFYIQFVAKEDKAIVYKTIEDNLYVKE YINISKKEIEMKSTSNNDAVENKLKDNNKVSKSYQNNYTEDEIQEDVLNEKTDMEKDSLSEENEHLPISKQSIMSVNLEK LDLLQNIVGEIVIMESMVVNSVNSTGVDIDNFNKATRQLHKLTDELQDIVMSMRMIQIAGVFQKMHRIVRDMNKKLDKNV ELITIGAETEVDKSVIDNLAEPFMHLIRNAMDHAIEPIEERIAKGKEEVGKIVLSAENLGGEAVISISDDGRGIMRDKIL AKAKEQGLLKHQSNEYTDDEVNSLIMTPGFSTKESITEFSGRGVGMDIVRKSIEKVGGSIEVKSKQDEGTTFTIKIPLTL SIVEGMKFKVGDSLFTLPISSIRRTFKLTDLNQIITEGNKTELITIYGACIPIIRLHKIYNIQTKVTNLMNGNMIIIENE HKAVCIFVDEIIGNQQVVVKPFPVYFNRFNIKNKGLSGCTILGDGSISLIIDADSIIEIY >Mature_700_residues MRQMLDMFIFETSLLLEQLDEIMIQIEKEKVFTHNNINETFRIMHTIKGSASMMGLDNISALAHSVEDLFYAIREGKIEV LDNDLLFDLVFQSLDFIRRDIDELQSRGCISSDYSNFIEGIEEYVSTLELSSSMKSKDNANLESKDEKEVIDSNFEYKED SDVVKIIFEQGCMMENVRAFMLVFELRDYCEFIDFYPKDVETNAESTEYIKSYGFYIQFVAKEDKAIVYKTIEDNLYVKE YINISKKEIEMKSTSNNDAVENKLKDNNKVSKSYQNNYTEDEIQEDVLNEKTDMEKDSLSEENEHLPISKQSIMSVNLEK LDLLQNIVGEIVIMESMVVNSVNSTGVDIDNFNKATRQLHKLTDELQDIVMSMRMIQIAGVFQKMHRIVRDMNKKLDKNV ELITIGAETEVDKSVIDNLAEPFMHLIRNAMDHAIEPIEERIAKGKEEVGKIVLSAENLGGEAVISISDDGRGIMRDKIL AKAKEQGLLKHQSNEYTDDEVNSLIMTPGFSTKESITEFSGRGVGMDIVRKSIEKVGGSIEVKSKQDEGTTFTIKIPLTL SIVEGMKFKVGDSLFTLPISSIRRTFKLTDLNQIITEGNKTELITIYGACIPIIRLHKIYNIQTKVTNLMNGNMIIIENE HKAVCIFVDEIIGNQQVVVKPFPVYFNRFNIKNKGLSGCTILGDGSISLIIDADSIIEIY
Specific function: Involved in the transmission of sensory signals from the chemoreceptors to the flagellar motors. CheA is autophosphorylated; it can transfer its phosphate group to either CheB or CheY [H]
COG id: COG0643
COG function: function code NT; Chemotaxis protein histidine kinase and related kinases
Gene ontology:
Cell location: Membrane (Potential). Note=It is not known whether CheA is actually membrane bound although CheA has two regions at the C-terminal end with the potential to be transmembrane regions [H]
Metaboloic importance: Non_Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Contains 1 HPt domain [H]
Homologues:
Organism=Escherichia coli, GI1788197, Length=384, Percent_Identity=41.40625, Blast_Score=305, Evalue=5e-84,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR003594 - InterPro: IPR002545 - InterPro: IPR004358 - InterPro: IPR008207 - InterPro: IPR004105 - InterPro: IPR005467 - InterPro: IPR009082 - InterPro: IPR010808 [H]
Pfam domain/function: PF01584 CheW; PF02895 H-kinase_dim; PF02518 HATPase_c; PF01627 Hpt; PF07194 P2 [H]
EC number: =2.7.13.3 [H]
Molecular weight: Translated: 79717; Mature: 79717
Theoretical pI: Translated: 4.50; Mature: 4.50
Prosite motif: PS50851 CHEW ; PS50894 HPT ; PS50109 HIS_KIN
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.9 %Cys (Translated Protein) 4.1 %Met (Translated Protein) 5.0 %Cys+Met (Translated Protein) 0.9 %Cys (Mature Protein) 4.1 %Met (Mature Protein) 5.0 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MRQMLDMFIFETSLLLEQLDEIMIQIEKEKVFTHNNINETFRIMHTIKGSASMMGLDNIS CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCHHHHHHHHHHCCCCHHCCCHHHH ALAHSVEDLFYAIREGKIEVLDNDLLFDLVFQSLDFIRRDIDELQSRGCISSDYSNFIEG HHHHHHHHHHHHHHCCCEEEECCHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHH IEEYVSTLELSSSMKSKDNANLESKDEKEVIDSNFEYKEDSDVVKIIFEQGCMMENVRAF HHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHCCCCCCCCCCHHHHHHHHCCCHHHHHHHH MLVFELRDYCEFIDFYPKDVETNAESTEYIKSYGFYIQFVAKEDKAIVYKTIEDNLYVKE HHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHCCEEEEEEECCCCEEEEEEECCCEEEHH YINISKKEIEMKSTSNNDAVENKLKDNNKVSKSYQNNYTEDEIQEDVLNEKTDMEKDSLS HHCCCHHHEEECCCCCCHHHHHHHCCCCHHHHHHHCCCCHHHHHHHHHCCCCCCCHHHCC EENEHLPISKQSIMSVNLEKLDLLQNIVGEIVIMESMVVNSVNSTGVDIDNFNKATRQLH CCCCCCCCCHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHH KLTDELQDIVMSMRMIQIAGVFQKMHRIVRDMNKKLDKNVELITIGAETEVDKSVIDNLA HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCHHHHHHHHHHH EPFMHLIRNAMDHAIEPIEERIAKGKEEVGKIVLSAENLGGEAVISISDDGRGIMRDKIL HHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHEEEEECCCCCEEEEEECCCCCCHHHHHHH AKAKEQGLLKHQSNEYTDDEVNSLIMTPGFSTKESITEFSGRGVGMDIVRKSIEKVGGSI HHHHHCCHHHCCCCCCCCHHHCEEEECCCCCCHHHHHHHCCCCCCHHHHHHHHHHCCCEE EVKSKQDEGTTFTIKIPLTLSIVEGMKFKVGDSLFTLPISSIRRTFKLTDLNQIITEGNK EEECCCCCCCEEEEEEEEEEEECCCCEEECCCCEEEEEHHHHHHHHHHHHHHHHHHCCCC TELITIYGACIPIIRLHKIYNIQTKVTNLMNGNMIIIENEHKAVCIFVDEIIGNQQVVVK EEEEEEHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCEEEEEEHHHHCCCEEEEE PFPVYFNRFNIKNKGLSGCTILGDGSISLIIDADSIIEIY ECCEEEEEEECCCCCCCCEEEEECCCEEEEEECCCEEEEC >Mature Secondary Structure MRQMLDMFIFETSLLLEQLDEIMIQIEKEKVFTHNNINETFRIMHTIKGSASMMGLDNIS CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCHHHHHHHHHHCCCCHHCCCHHHH ALAHSVEDLFYAIREGKIEVLDNDLLFDLVFQSLDFIRRDIDELQSRGCISSDYSNFIEG HHHHHHHHHHHHHHCCCEEEECCHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHH IEEYVSTLELSSSMKSKDNANLESKDEKEVIDSNFEYKEDSDVVKIIFEQGCMMENVRAF HHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHCCCCCCCCCCHHHHHHHHCCCHHHHHHHH MLVFELRDYCEFIDFYPKDVETNAESTEYIKSYGFYIQFVAKEDKAIVYKTIEDNLYVKE HHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHCCEEEEEEECCCCEEEEEEECCCEEEHH YINISKKEIEMKSTSNNDAVENKLKDNNKVSKSYQNNYTEDEIQEDVLNEKTDMEKDSLS HHCCCHHHEEECCCCCCHHHHHHHCCCCHHHHHHHCCCCHHHHHHHHHCCCCCCCHHHCC EENEHLPISKQSIMSVNLEKLDLLQNIVGEIVIMESMVVNSVNSTGVDIDNFNKATRQLH CCCCCCCCCHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHH KLTDELQDIVMSMRMIQIAGVFQKMHRIVRDMNKKLDKNVELITIGAETEVDKSVIDNLA HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCHHHHHHHHHHH EPFMHLIRNAMDHAIEPIEERIAKGKEEVGKIVLSAENLGGEAVISISDDGRGIMRDKIL HHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHEEEEECCCCCEEEEEECCCCCCHHHHHHH AKAKEQGLLKHQSNEYTDDEVNSLIMTPGFSTKESITEFSGRGVGMDIVRKSIEKVGGSI HHHHHCCHHHCCCCCCCCHHHCEEEECCCCCCHHHHHHHCCCCCCHHHHHHHHHHCCCEE EVKSKQDEGTTFTIKIPLTLSIVEGMKFKVGDSLFTLPISSIRRTFKLTDLNQIITEGNK EEECCCCCCCEEEEEEEEEEEECCCCEEECCCCEEEEEHHHHHHHHHHHHHHHHHHCCCC TELITIYGACIPIIRLHKIYNIQTKVTNLMNGNMIIIENEHKAVCIFVDEIIGNQQVVVK EEEEEEHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCEEEEEEHHHHCCCEEEEE PFPVYFNRFNIKNKGLSGCTILGDGSISLIIDADSIIEIY ECCEEEEEEECCCCCCCCEEEEECCCEEEEEECCCEEEEC
PDB accession: NA
Resolution: NA
Structure class: Alpha Beta
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 6.0
TargetDB status: NA
Availability: NA
References: 1938941; 9384377 [H]