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The map label for this gene is 126698005

Identifier: 126698005

GI number: 126698005

Start: 515285

End: 516637

Strand: Direct

Name: 126698005

Synonym: CD0434

Alternate gene names: NA

Gene position: 515285-516637 (Clockwise)

Preceding gene: 126698004

Following gene: 126698006

Centisome position: 12.01

GC content: 37.18

Gene sequence:

>1353_bases
GTGAAACAAGAGATGAAAGAACAATTACTAACTAAAAGACCGATAGATTTACTATTTCAGCTATCTATTCCAGCGGTTAT
AGGAATGATAGTTATCGGTCTATATCCCTTGATGGACGGAATATTTGCCGGGAAAATTATAGGACAAACGGCTATGACAG
CTTGTGGTGTTGCAATGCCATTAACATTTTTTAACAGTGGAGTGTCTACACTTCTTGGTGTTGGTTCGGCATCCGTTCTT
TCCAGAGCAATAGGAAAAGGAGATCAGAAAACTGTCGATAAAATTATGGGGAACTTAATCTATTGGGTAATTTTCTTCTC
TGTAATTATCACAGTTGGAGGAATAATCCTTGCACCACACTTTTTATCTATGGTGGGTGCAACAGGTGAAATCAAAGCCT
ATGGCATTAGATACCTTAGAGTAATTTTCATTGGCTCCCTATTTGTGAACTTTACACAGTCAGCCAACATGGTTATGCGT
GGTGAAGGGCTGATGAAAAAAGCTATGACGATTATGGGGCTTGGAGCTTTGCTGAATATTATTCTTGATCCAATCCTAAT
GACTGTTATGGGAAAATATGCTATTGAAGGTGCTGCTCTTGCAACTATTATAGCACAGTTTGTTCAAGCTGTTGTAACGA
TGCACTATTTCTTGAAGAAGAGTAAGGTTGTTAAAATCCATAGGATAAAGTCGGATGCTGAAATAAAAAAAGAAATGTTC
GGTGTGGGTTCTTCCGCTATGATGATGCAACTCCTATTCATGATTCAGCAGACAATGCTATATAAAATGGCATTTAAATA
TGGCGGAGATCCGAATGGGATTTTGATGGCAGCCTCACTTCGTGTATATGCCTTTTCATTTATTCCTCTTTGGGGAATGA
GCCAAGGCTTACAACCTGTTGTCGGAACAAACTTTGGAGCAAAGCAATATGATAGAGTAAGGCAGGCTATGAAAGTATTT
TCTATTGGAGGGCTTATCCTTGCAGCAATTTTTTGGATTCCATCCTTGTTGCTATCAAGTCAGATACTTTCATTGTTTGG
AGTAGAAGCAGATATTATTGCACATGGAGTTGGTAATTTCAGGCTGTTCTATTCTGTATTTGTTTTGTATGGAGTAATGG
TTATGAGTATTACATTTTTCCAATCAATCGGAAATGGAAAAAAAGCCGGAATCATTGTAATGCTGAGACAATTGTTTTTG
TTTGTTCCTGCCATGATTTTATTACCAATGATGTTTGGTGTAAAAGCCGTTTGGTTTACTCAACCGCTTGTAGATTTCAT
TATGATTGTTGTTGGAATATTTATGATGATTAGTGAGTTGAATAAAATGGGGAAAGAAAAGGTAAAAGTTTAA

Upstream 100 bases:

>100_bases
TGATGAACTGATGAAATCATCTTCAATATATAAAAAGTTTATAGAACAAAGAGAAAAAGCTATTCAGTGGAAATTAAATG
ATTAAGGGAGGAGCTATAGA

Downstream 100 bases:

>100_bases
AACTCTGCTTTGTCGTGCAATGAAATTGTTTTGGAAAGGGAGTGTTATGAAGATATTTTTGCTATAAGAGATGGAGGAAG
AAGAATGAATGCAACTATAT

Product: drug/sodium antiporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 450; Mature: 450

Protein sequence:

>450_residues
MKQEMKEQLLTKRPIDLLFQLSIPAVIGMIVIGLYPLMDGIFAGKIIGQTAMTACGVAMPLTFFNSGVSTLLGVGSASVL
SRAIGKGDQKTVDKIMGNLIYWVIFFSVIITVGGIILAPHFLSMVGATGEIKAYGIRYLRVIFIGSLFVNFTQSANMVMR
GEGLMKKAMTIMGLGALLNIILDPILMTVMGKYAIEGAALATIIAQFVQAVVTMHYFLKKSKVVKIHRIKSDAEIKKEMF
GVGSSAMMMQLLFMIQQTMLYKMAFKYGGDPNGILMAASLRVYAFSFIPLWGMSQGLQPVVGTNFGAKQYDRVRQAMKVF
SIGGLILAAIFWIPSLLLSSQILSLFGVEADIIAHGVGNFRLFYSVFVLYGVMVMSITFFQSIGNGKKAGIIVMLRQLFL
FVPAMILLPMMFGVKAVWFTQPLVDFIMIVVGIFMMISELNKMGKEKVKV

Sequences:

>Translated_450_residues
MKQEMKEQLLTKRPIDLLFQLSIPAVIGMIVIGLYPLMDGIFAGKIIGQTAMTACGVAMPLTFFNSGVSTLLGVGSASVL
SRAIGKGDQKTVDKIMGNLIYWVIFFSVIITVGGIILAPHFLSMVGATGEIKAYGIRYLRVIFIGSLFVNFTQSANMVMR
GEGLMKKAMTIMGLGALLNIILDPILMTVMGKYAIEGAALATIIAQFVQAVVTMHYFLKKSKVVKIHRIKSDAEIKKEMF
GVGSSAMMMQLLFMIQQTMLYKMAFKYGGDPNGILMAASLRVYAFSFIPLWGMSQGLQPVVGTNFGAKQYDRVRQAMKVF
SIGGLILAAIFWIPSLLLSSQILSLFGVEADIIAHGVGNFRLFYSVFVLYGVMVMSITFFQSIGNGKKAGIIVMLRQLFL
FVPAMILLPMMFGVKAVWFTQPLVDFIMIVVGIFMMISELNKMGKEKVKV
>Mature_450_residues
MKQEMKEQLLTKRPIDLLFQLSIPAVIGMIVIGLYPLMDGIFAGKIIGQTAMTACGVAMPLTFFNSGVSTLLGVGSASVL
SRAIGKGDQKTVDKIMGNLIYWVIFFSVIITVGGIILAPHFLSMVGATGEIKAYGIRYLRVIFIGSLFVNFTQSANMVMR
GEGLMKKAMTIMGLGALLNIILDPILMTVMGKYAIEGAALATIIAQFVQAVVTMHYFLKKSKVVKIHRIKSDAEIKKEMF
GVGSSAMMMQLLFMIQQTMLYKMAFKYGGDPNGILMAASLRVYAFSFIPLWGMSQGLQPVVGTNFGAKQYDRVRQAMKVF
SIGGLILAAIFWIPSLLLSSQILSLFGVEADIIAHGVGNFRLFYSVFVLYGVMVMSITFFQSIGNGKKAGIIVMLRQLFL
FVPAMILLPMMFGVKAVWFTQPLVDFIMIVVGIFMMISELNKMGKEKVKV

Specific function: Unknown

COG id: COG0534

COG function: function code V; Na+-driven multidrug efflux pump

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002528
- InterPro:   IPR015522 [H]

Pfam domain/function: PF01554 MatE [H]

EC number: NA

Molecular weight: Translated: 49416; Mature: 49416

Theoretical pI: Translated: 10.48; Mature: 10.48

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
8.0 %Met     (Translated Protein)
8.2 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
8.0 %Met     (Mature Protein)
8.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure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HHHHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]