Click here to switch to the map view.

The map label for this gene is licC [H]

Identifier: 126697782

GI number: 126697782

Start: 274956

End: 275681

Strand: Direct

Name: licC [H]

Synonym: CD0211

Alternate gene names: 126697782

Gene position: 274956-275681 (Clockwise)

Preceding gene: 126697781

Following gene: 126697783

Centisome position: 6.41

GC content: 24.93

Gene sequence:

>726_bases
ATGAAAGCAATAATTTTAGCAGCTGGGCTGGGGACACGATTAAAACCATTAACTTCAGAGTGCCCAAAACCATTAGTTAA
AGTTAATGGGAAGCCAATGATAGAAACCCAAATAGAATGTCTATTAGAAAAGGGGATAAAAGATATAAAAGTTGCAGTAG
GTTATTTAAAAGAAAAATTTTATTATTTAGCGGAAAAATATAATGTGGAATTAATATATAACAATAAATATGATATATAC
AATAATATTTATACTATGTATTTATTAAGAGAACATTTACCTGATAGCTATGTTATAGAGGGAGATGTATATATATGTAA
TAACTTTATAGATCCAGATATAAAGGAATCCACTTATTTTACTCTTTATAAAGAAAATTTTAACAATGAGTTTATATTTA
AATTTGATGAAAATAATAAGGTTTATGATATGTATGTTGGTGATAATAAGGGATATATATTATGTGGTGTATCCTATTGG
TCATTAACAGATGGAAATATTATAGCAAAAAAATTAGAGGAAACAATAGAAAATGGAGACTTTGAAAGTCTATTTTGGGA
TGATGTTGTAATGAAAAATAAAGATGCTTTAAATATGTACATTCAGAAAATAGATTTTAAAGATTGTTTTGAAATAGATA
ATGAAAAAGATTTGAGATTTTCGGAAAAATGTATAGTGCAAAATAATAAATTTACAATGAAGAAAATTTTACAATACTCT
AAGTAG

Upstream 100 bases:

>100_bases
TAATAAAAAATTTCTATCGGAATATTTGGAGATTTTATAAGTGATACTAACTTAAAACCTCTAAAACATTACAATATTCA
ATTGGAAGGTAGGATTAAAT

Downstream 100 bases:

>100_bases
GTTAGGAAGGGATTTGTATGGGAATTTTAGATGAAATAATGAACCAAGAGCATTTTGATATAAAAACATCACTAGATTAT
ATTAATGAGTATGAGAAGCT

Product: CTP:phosphocholine cytidylyltransferase

Products: dTDPglucose; Diphosphate [C]

Alternate protein names: NA

Number of amino acids: Translated: 241; Mature: 241

Protein sequence:

>241_residues
MKAIILAAGLGTRLKPLTSECPKPLVKVNGKPMIETQIECLLEKGIKDIKVAVGYLKEKFYYLAEKYNVELIYNNKYDIY
NNIYTMYLLREHLPDSYVIEGDVYICNNFIDPDIKESTYFTLYKENFNNEFIFKFDENNKVYDMYVGDNKGYILCGVSYW
SLTDGNIIAKKLEETIENGDFESLFWDDVVMKNKDALNMYIQKIDFKDCFEIDNEKDLRFSEKCIVQNNKFTMKKILQYS
K

Sequences:

>Translated_241_residues
MKAIILAAGLGTRLKPLTSECPKPLVKVNGKPMIETQIECLLEKGIKDIKVAVGYLKEKFYYLAEKYNVELIYNNKYDIY
NNIYTMYLLREHLPDSYVIEGDVYICNNFIDPDIKESTYFTLYKENFNNEFIFKFDENNKVYDMYVGDNKGYILCGVSYW
SLTDGNIIAKKLEETIENGDFESLFWDDVVMKNKDALNMYIQKIDFKDCFEIDNEKDLRFSEKCIVQNNKFTMKKILQYS
K
>Mature_241_residues
MKAIILAAGLGTRLKPLTSECPKPLVKVNGKPMIETQIECLLEKGIKDIKVAVGYLKEKFYYLAEKYNVELIYNNKYDIY
NNIYTMYLLREHLPDSYVIEGDVYICNNFIDPDIKESTYFTLYKENFNNEFIFKFDENNKVYDMYVGDNKGYILCGVSYW
SLTDGNIIAKKLEETIENGDFESLFWDDVVMKNKDALNMYIQKIDFKDCFEIDNEKDLRFSEKCIVQNNKFTMKKILQYS
K

Specific function: Catalyzes The Formation Of Dtdp-Glucose, From Dttp And Glucose 1-Phosphate, As Well As Its Pyrophosphorolysis. [C]

COG id: COG4750

COG function: function code M; CTP:phosphocholine cytidylyltransferase involved in choline phosphorylation for cell surface LPS epitopes

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Caenorhabditis elegans, GI133931050, Length=114, Percent_Identity=37.719298245614, Blast_Score=72, Evalue=2e-13,
Organism=Saccharomyces cerevisiae, GI6320148, Length=79, Percent_Identity=44.3037974683544, Blast_Score=67, Evalue=3e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017189
- InterPro:   IPR005835 [H]

Pfam domain/function: PF00483 NTP_transferase [H]

EC number: 2.7.7.24 [C]

Molecular weight: Translated: 28409; Mature: 28409

Theoretical pI: Translated: 4.84; Mature: 4.84

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.5 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
5.4 %Cys+Met (Translated Protein)
2.5 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
5.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKAIILAAGLGTRLKPLTSECPKPLVKVNGKPMIETQIECLLEKGIKDIKVAVGYLKEKF
CCEEEEEECCCCCCCCHHHHCCCCCEEECCCCCHHHHHHHHHHHCHHHHHHHHHHHHHHH
YYLAEKYNVELIYNNKYDIYNNIYTMYLLREHLPDSYVIEGDVYICNNFIDPDIKESTYF
HHHHHHEEEEEEECCCCCHHHHHHHEEHHHHHCCCCEEEECCEEEECCCCCCCCCCCEEE
TLYKENFNNEFIFKFDENNKVYDMYVGDNKGYILCGVSYWSLTDGNIIAKKLEETIENGD
EEEEECCCCEEEEEECCCCEEEEEEECCCCCEEEEEEEEEEECCCCHHHHHHHHHHHCCC
FESLFWDDVVMKNKDALNMYIQKIDFKDCFEIDNEKDLRFSEKCIVQNNKFTMKKILQYS
CCCEEHHHHHHCCCHHHHHHHHHCCCHHHHCCCCCCCCEECCEEEEECCCHHHHHHHHCC
K
C
>Mature Secondary Structure
MKAIILAAGLGTRLKPLTSECPKPLVKVNGKPMIETQIECLLEKGIKDIKVAVGYLKEKF
CCEEEEEECCCCCCCCHHHHCCCCCEEECCCCCHHHHHHHHHHHCHHHHHHHHHHHHHHH
YYLAEKYNVELIYNNKYDIYNNIYTMYLLREHLPDSYVIEGDVYICNNFIDPDIKESTYF
HHHHHHEEEEEEECCCCCHHHHHHHEEHHHHHCCCCEEEECCEEEECCCCCCCCCCCEEE
TLYKENFNNEFIFKFDENNKVYDMYVGDNKGYILCGVSYWSLTDGNIIAKKLEETIENGD
EEEEECCCCEEEEEECCCCEEEEEEECCCCCEEEEEEEEEEECCCCHHHHHHHHHHHCCC
FESLFWDDVVMKNKDALNMYIQKIDFKDCFEIDNEKDLRFSEKCIVQNNKFTMKKILQYS
CCCEEHHHHHHCCCHHHHHHHHHCCCHHHHCCCCCCCCEECCEEEEECCCHHHHHHHHCC
K
C

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: dTTP; D-Glucose 1-phosphate; H+ [C]

Specific reaction: dTTP + D-Glucose 1-phosphate + H+ --> dTDPglucose + Diphosphate [C]

General reaction: Nucleotidyl group transfer [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2479481; 7542800 [H]