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The map label for this gene is hpdB

Identifier: 126697725

GI number: 126697725

Start: 202040

End: 204748

Strand: Direct

Name: hpdB

Synonym: CD0153

Alternate gene names: 126697725

Gene position: 202040-204748 (Clockwise)

Preceding gene: 126697724

Following gene: 126697726

Centisome position: 4.71

GC content: 32.41

Gene sequence:

>2709_bases
ATGAGTCAAAGTAAAGAAGACAAAATAAGAAGTATTTTGGAAGCAAAAAATATTAAATCAAATTTTCAAAATAAAGAAAA
TTTAAGTGAATTTAATGAAAAAAAAGCAAGTAAAAGAGCAGAAGACTTATTAGATGTATATTATAATACATTATCTACTG
CTGATATGGAATTTCCATATTGGTATAATAGAGAATATAGAAAATCAGATGGTGATATACCAGTAGTTAGAAGAGCTAAA
GCTCTTAAAGCTGCTTTTTCACATATGACACCAAATATAATACCTGGTGAGAAAATAGTAATGCAAAAGACACGCCATTA
TAGAGGTTCTTTTCCAATGCCATGGGTAAGTGAAAGCTTCTTTGTTGCTCAAGGAGAACAAATGAGAGAAGAGGCAAAGA
AATTAGCCAGTAACACAGCTGATGAACTTACAAAATTTGGGTCTGGTGGAGGAAATGTTACTGAAAGTTTTGGAAATGTC
GTTTCAATAGCTGGTAAATTCGGAATGAGAAAAGAAGAAGTACCTGTACTTGTAAAAATGGCAAAGGAATGGGTTGGAAA
GTCTGTTGAAGATTTAGGTTTTCACTATGAAAAAATGATGCCAGATTATGATTTAAAAGAAAACCTAATGAGTACACTTA
TATGCATGTTTGATTCAGGGTATACACTTCCTCAAGGTAGAGAAGTTATAAATTATTTTTATCCTTTAAATTATGGATTA
GATGGAATTATAGAAATGGCAAAAGAATGTAAAAAGGCAGTTGCAGGAAATGCATCTGGAGATGGGCTTATTGGTATGGA
CCGTCTATATTTTTATGAGGCTGTTATTCAAGTTATTGAAGGATTACAAACTTGGATTTTAAATTATGCAAAACATGCAA
AATACTTAGAAAGTATAGAGACAGATTTAGAAGCTAAAAAAGAATACTCAGATTTAGTGGAGATATTAGAACATATTGCA
CATAAACAACCTCGTACATTTAGGGAAGCTCTTCAGTTGACTTATACAATTCATATAGCATCAGTAAATGAGGATGCTAT
ATCTGGTATGTCTATAGGACGTTTTGGTCAAATTTTATATCCTTGGTATGAACAAGATATAGAAAAAGGACTAATTACAA
AAGAAGAGGTTATCGAATTATTAGAGCTTTATAGAATAAAAATCACTTGTATTGACTGTTTTGCTTCAGCGGGCGTAAAT
GGAGGAGTACTATCAGGCAATACATTTAATACTTTATCTATAGGTGGATTAAAAGAAGATGGTTCTACAGGAGCTAATGA
ACTAGAAGAGTTATTATTAGAAGCAAGTATGAGATGTAGAACTCCTCAACCTAGTTTAACTATGCTATATGATGAAAAGC
TTCCAGAAGATTTCTTAATGAAAGCTGCTGAATGTACAAAGCTTGGTTCTGGTTATCCAGCATGGGTAAACAACTCAAAT
GGAACAACATTTATGATGAAACAATTTGCTGATGAAGGTATGACTGTTGAAGAAGCAAGAGCATTTGCATTAGGTGGATG
TTTGGAAACGTCTCCAGGGTGTTGGAAACAGTTAACTTTAAACGGAAAAACGTACTCTATTGCAGGTGGAGCAGGTCAAT
CTGCTGGCTCTGGAGTTCACTTTATAGCTAATCCAAAAATTTTAGAACTTGTTCTTATGAATGGTAAAGACTATCGTATG
AATATACAAGTATTTGAGCCTCATAATAAGCCATTAGATACTTATGAAGAAGTCATAGAAGTATTTAAAGATTATTATAA
ACAAGCAATAAATGTTTTAGAAAGAGCAAATAACATTGAGTTAGATATATGGAGAAAATTTGATACTTCTATAATAAATT
CACTACTAAAGCCAGACTGTTTAGACAAAGGTCAACATATAGGAAATATGGGATATCGTTATAATGCAACATTAAACGTA
GAAACTTGTGGTACTGTTACTATGGTCAATTCATTTGCAGCTCTTAAGAAACTTGTATATGATGACAAAGCATTTACAAT
AGAGGAAATGAAGGATGCCATATTAAATAATTTTGGATTTAAAGATGCATTAGAAGTAGGAAATTATTCTATGGCAGACC
AAGTAAAAGTAGATAAGACTGGTAAATATGATGCTATTTATAAGGCCTGTCTTGATGCACCTAAATATGGAAATAATGAT
TTGTATGCAGATAATATTCTTAAAAACTATGAGGTATGGTTATCAAAAGTATGTGAAGAAGCACAATCTTTATATGCTAA
GAAGATGTACCCTTGCCAAATATCTGTTTCTACACATGGGCCACAGGGAGCTGCTACCTTGGCTACTCCAGATGGTAGAC
TAAGTGGAACAACATATTCAGATGGTTCAGTCTCTGCATATGCAGGAACAGATAAAAATGGAGTATATGCATTATTTGAA
TCTGCAACTATTTGGGACCAAGCAGTAGTTCAAAATTCTCAGATGAATTTAAAACTTCATCCAACTACTATAAAAGGACA
ACAAGGAACTAAAAAATTATTAGATTTAACAAGAAGTTATTTAAGAAAAGGTGGGTTCCATATTCAATATAATGTTGTAG
ATTCAGAAACATTAAAAGATGCACAAAAAAATCCTGACAATTATCGTCAATTAATGGTACGTGTTGCTGGGTTTACTCAA
TATTGGTGTGAATTAGGTAAACCAATACAAGATGAAGTAATTGCTAGAACAGAGTATGAAGGGGTGTAA

Upstream 100 bases:

>100_bases
TTTCTATAGAAAGATTATTTTAAAAAGTGGGTAATATACCCTTTTTTTTCATTCTTAAAAAGTTTTATACTAATTATAGA
AAGATTAAGGAGGGGAAGAA

Downstream 100 bases:

>100_bases
AATATGAGAAAGCATAGTGATTGTATGAATTTTTGTGCAGTGGATGCAACCAAAGGAATTTGTAGATTATCAAAACAAAT
GATTAATTTAGATGATGCAG

Product: 4-hydroxyphenylacetate decarboxylase, catalytic subunit

Products: NA

Alternate protein names: 4-hydroxyphenylacetate decarboxylase glycyl radical subunit; p-hydroxyphenylacetate decarboxylase large subunit

Number of amino acids: Translated: 902; Mature: 901

Protein sequence:

>902_residues
MSQSKEDKIRSILEAKNIKSNFQNKENLSEFNEKKASKRAEDLLDVYYNTLSTADMEFPYWYNREYRKSDGDIPVVRRAK
ALKAAFSHMTPNIIPGEKIVMQKTRHYRGSFPMPWVSESFFVAQGEQMREEAKKLASNTADELTKFGSGGGNVTESFGNV
VSIAGKFGMRKEEVPVLVKMAKEWVGKSVEDLGFHYEKMMPDYDLKENLMSTLICMFDSGYTLPQGREVINYFYPLNYGL
DGIIEMAKECKKAVAGNASGDGLIGMDRLYFYEAVIQVIEGLQTWILNYAKHAKYLESIETDLEAKKEYSDLVEILEHIA
HKQPRTFREALQLTYTIHIASVNEDAISGMSIGRFGQILYPWYEQDIEKGLITKEEVIELLELYRIKITCIDCFASAGVN
GGVLSGNTFNTLSIGGLKEDGSTGANELEELLLEASMRCRTPQPSLTMLYDEKLPEDFLMKAAECTKLGSGYPAWVNNSN
GTTFMMKQFADEGMTVEEARAFALGGCLETSPGCWKQLTLNGKTYSIAGGAGQSAGSGVHFIANPKILELVLMNGKDYRM
NIQVFEPHNKPLDTYEEVIEVFKDYYKQAINVLERANNIELDIWRKFDTSIINSLLKPDCLDKGQHIGNMGYRYNATLNV
ETCGTVTMVNSFAALKKLVYDDKAFTIEEMKDAILNNFGFKDALEVGNYSMADQVKVDKTGKYDAIYKACLDAPKYGNND
LYADNILKNYEVWLSKVCEEAQSLYAKKMYPCQISVSTHGPQGAATLATPDGRLSGTTYSDGSVSAYAGTDKNGVYALFE
SATIWDQAVVQNSQMNLKLHPTTIKGQQGTKKLLDLTRSYLRKGGFHIQYNVVDSETLKDAQKNPDNYRQLMVRVAGFTQ
YWCELGKPIQDEVIARTEYEGV

Sequences:

>Translated_902_residues
MSQSKEDKIRSILEAKNIKSNFQNKENLSEFNEKKASKRAEDLLDVYYNTLSTADMEFPYWYNREYRKSDGDIPVVRRAK
ALKAAFSHMTPNIIPGEKIVMQKTRHYRGSFPMPWVSESFFVAQGEQMREEAKKLASNTADELTKFGSGGGNVTESFGNV
VSIAGKFGMRKEEVPVLVKMAKEWVGKSVEDLGFHYEKMMPDYDLKENLMSTLICMFDSGYTLPQGREVINYFYPLNYGL
DGIIEMAKECKKAVAGNASGDGLIGMDRLYFYEAVIQVIEGLQTWILNYAKHAKYLESIETDLEAKKEYSDLVEILEHIA
HKQPRTFREALQLTYTIHIASVNEDAISGMSIGRFGQILYPWYEQDIEKGLITKEEVIELLELYRIKITCIDCFASAGVN
GGVLSGNTFNTLSIGGLKEDGSTGANELEELLLEASMRCRTPQPSLTMLYDEKLPEDFLMKAAECTKLGSGYPAWVNNSN
GTTFMMKQFADEGMTVEEARAFALGGCLETSPGCWKQLTLNGKTYSIAGGAGQSAGSGVHFIANPKILELVLMNGKDYRM
NIQVFEPHNKPLDTYEEVIEVFKDYYKQAINVLERANNIELDIWRKFDTSIINSLLKPDCLDKGQHIGNMGYRYNATLNV
ETCGTVTMVNSFAALKKLVYDDKAFTIEEMKDAILNNFGFKDALEVGNYSMADQVKVDKTGKYDAIYKACLDAPKYGNND
LYADNILKNYEVWLSKVCEEAQSLYAKKMYPCQISVSTHGPQGAATLATPDGRLSGTTYSDGSVSAYAGTDKNGVYALFE
SATIWDQAVVQNSQMNLKLHPTTIKGQQGTKKLLDLTRSYLRKGGFHIQYNVVDSETLKDAQKNPDNYRQLMVRVAGFTQ
YWCELGKPIQDEVIARTEYEGV
>Mature_901_residues
SQSKEDKIRSILEAKNIKSNFQNKENLSEFNEKKASKRAEDLLDVYYNTLSTADMEFPYWYNREYRKSDGDIPVVRRAKA
LKAAFSHMTPNIIPGEKIVMQKTRHYRGSFPMPWVSESFFVAQGEQMREEAKKLASNTADELTKFGSGGGNVTESFGNVV
SIAGKFGMRKEEVPVLVKMAKEWVGKSVEDLGFHYEKMMPDYDLKENLMSTLICMFDSGYTLPQGREVINYFYPLNYGLD
GIIEMAKECKKAVAGNASGDGLIGMDRLYFYEAVIQVIEGLQTWILNYAKHAKYLESIETDLEAKKEYSDLVEILEHIAH
KQPRTFREALQLTYTIHIASVNEDAISGMSIGRFGQILYPWYEQDIEKGLITKEEVIELLELYRIKITCIDCFASAGVNG
GVLSGNTFNTLSIGGLKEDGSTGANELEELLLEASMRCRTPQPSLTMLYDEKLPEDFLMKAAECTKLGSGYPAWVNNSNG
TTFMMKQFADEGMTVEEARAFALGGCLETSPGCWKQLTLNGKTYSIAGGAGQSAGSGVHFIANPKILELVLMNGKDYRMN
IQVFEPHNKPLDTYEEVIEVFKDYYKQAINVLERANNIELDIWRKFDTSIINSLLKPDCLDKGQHIGNMGYRYNATLNVE
TCGTVTMVNSFAALKKLVYDDKAFTIEEMKDAILNNFGFKDALEVGNYSMADQVKVDKTGKYDAIYKACLDAPKYGNNDL
YADNILKNYEVWLSKVCEEAQSLYAKKMYPCQISVSTHGPQGAATLATPDGRLSGTTYSDGSVSAYAGTDKNGVYALFES
ATIWDQAVVQNSQMNLKLHPTTIKGQQGTKKLLDLTRSYLRKGGFHIQYNVVDSETLKDAQKNPDNYRQLMVRVAGFTQY
WCELGKPIQDEVIARTEYEGV

Specific function: Decarboxylates phenylacetates with a hydroxyl group in the p-position. Active toward 4-hydroxyphenylacetate, 3,4- dihydroxyphenylacetate and p-hydroxymandelate, forming 4- methylphenol, 4-methylcatechol and p-hydroxybenzylalcohol respectively

COG id: COG1882

COG function: function code C; Pyruvate-formate lyase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 pyruvate formate lyase domain

Homologues:

Organism=Escherichia coli, GI1790388, Length=849, Percent_Identity=27.0906949352179, Blast_Score=284, Evalue=2e-77,
Organism=Escherichia coli, GI1787044, Length=757, Percent_Identity=27.7410832232497, Blast_Score=252, Evalue=6e-68,
Organism=Escherichia coli, GI1787131, Length=195, Percent_Identity=27.6923076923077, Blast_Score=71, Evalue=4e-13,
Organism=Escherichia coli, GI48994926, Length=194, Percent_Identity=27.8350515463918, Blast_Score=69, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): HPDL_CLOD6 (Q18CP5)

Other databases:

- EMBL:   AM180355
- RefSeq:   YP_001086622.1
- STRING:   Q18CP5
- GeneID:   4914359
- GenomeReviews:   AM180355_GR
- KEGG:   cdf:CD0153
- NMPDR:   fig|1496.1.peg.1513
- eggNOG:   COG1882
- HOGENOM:   HBG422145
- ProtClustDB:   CLSK2322819
- GO:   GO:0005737
- InterPro:   IPR001150
- InterPro:   IPR004184

Pfam domain/function: PF01228 Gly_radical; PF02901 PFL

EC number: =4.1.1.83

Molecular weight: Translated: 101295; Mature: 101164

Theoretical pI: Translated: 5.20; Mature: 5.20

Prosite motif: PS00850 GLY_RADICAL_1; PS51149 GLY_RADICAL_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSQSKEDKIRSILEAKNIKSNFQNKENLSEFNEKKASKRAEDLLDVYYNTLSTADMEFPY
CCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
WYNREYRKSDGDIPVVRRAKALKAAFSHMTPNIIPGEKIVMQKTRHYRGSFPMPWVSESF
CCCCCHHCCCCCCHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCC
FVAQGEQMREEAKKLASNTADELTKFGSGGGNVTESFGNVVSIAGKFGMRKEEVPVLVKM
EECCCHHHHHHHHHHHCCCHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCCCCCHHHHHH
AKEWVGKSVEDLGFHYEKMMPDYDLKENLMSTLICMFDSGYTLPQGREVINYFYPLNYGL
HHHHHCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHCCCCCH
DGIIEMAKECKKAVAGNASGDGLIGMDRLYFYEAVIQVIEGLQTWILNYAKHAKYLESIE
HHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TDLEAKKEYSDLVEILEHIAHKQPRTFREALQLTYTIHIASVNEDAISGMSIGRFGQILY
HHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHEEEEEEEEECCHHHHCCCCHHHHHHHHH
PWYEQDIEKGLITKEEVIELLELYRIKITCIDCFASAGVNGGVLSGNTFNTLSIGGLKED
HHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEECCCCCCEEEECCCCCC
GSTGANELEELLLEASMRCRTPQPSLTMLYDEKLPEDFLMKAAECTKLGSGYPAWVNNSN
CCCCHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCHHHHHHHHHHHHCCCCCCCEEECCC
GTTFMMKQFADEGMTVEEARAFALGGCLETSPGCWKQLTLNGKTYSIAGGAGQSAGSGVH
CCEEHHHHHHCCCCCHHHHHHHHHCCCCCCCCCCCEEEEECCCEEEEECCCCCCCCCCEE
FIANPKILELVLMNGKDYRMNIQVFEPHNKPLDTYEEVIEVFKDYYKQAINVLERANNIE
EEECCCEEEEEEECCCCEEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCE
LDIWRKFDTSIINSLLKPDCLDKGQHIGNMGYRYNATLNVETCGTVTMVNSFAALKKLVY
EEEEHHHHHHHHHHHHCCCHHHCCCCCCCCCEEEEEEEEECCCCHHHHHHHHHHHHHHHH
DDKAFTIEEMKDAILNNFGFKDALEVGNYSMADQVKVDKTGKYDAIYKACLDAPKYGNND
CCCCCCHHHHHHHHHHCCCCHHHHHHCCCCCCCCEEECCCCCHHHHHHHHHCCCCCCCCC
LYADNILKNYEVWLSKVCEEAQSLYAKKMYPCQISVSTHGPQGAATLATPDGRLSGTTYS
CCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCEEEECCCCCCCCCCCC
DGSVSAYAGTDKNGVYALFESATIWDQAVVQNSQMNLKLHPTTIKGQQGTKKLLDLTRSY
CCCEEEECCCCCCCEEEEECCCHHHHHHHHCCCCCEEEECCCEECCCCHHHHHHHHHHHH
LRKGGFHIQYNVVDSETLKDAQKNPDNYRQLMVRVAGFTQYWCELGKPIQDEVIARTEYE
HHCCCCEEEEEECCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCC
GV
CC
>Mature Secondary Structure 
SQSKEDKIRSILEAKNIKSNFQNKENLSEFNEKKASKRAEDLLDVYYNTLSTADMEFPY
CCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
WYNREYRKSDGDIPVVRRAKALKAAFSHMTPNIIPGEKIVMQKTRHYRGSFPMPWVSESF
CCCCCHHCCCCCCHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCC
FVAQGEQMREEAKKLASNTADELTKFGSGGGNVTESFGNVVSIAGKFGMRKEEVPVLVKM
EECCCHHHHHHHHHHHCCCHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCCCCCHHHHHH
AKEWVGKSVEDLGFHYEKMMPDYDLKENLMSTLICMFDSGYTLPQGREVINYFYPLNYGL
HHHHHCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHCCCCCH
DGIIEMAKECKKAVAGNASGDGLIGMDRLYFYEAVIQVIEGLQTWILNYAKHAKYLESIE
HHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TDLEAKKEYSDLVEILEHIAHKQPRTFREALQLTYTIHIASVNEDAISGMSIGRFGQILY
HHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHEEEEEEEEECCHHHHCCCCHHHHHHHHH
PWYEQDIEKGLITKEEVIELLELYRIKITCIDCFASAGVNGGVLSGNTFNTLSIGGLKED
HHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEECCCCCCEEEECCCCCC
GSTGANELEELLLEASMRCRTPQPSLTMLYDEKLPEDFLMKAAECTKLGSGYPAWVNNSN
CCCCHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCHHHHHHHHHHHHCCCCCCCEEECCC
GTTFMMKQFADEGMTVEEARAFALGGCLETSPGCWKQLTLNGKTYSIAGGAGQSAGSGVH
CCEEHHHHHHCCCCCHHHHHHHHHCCCCCCCCCCCEEEEECCCEEEEECCCCCCCCCCEE
FIANPKILELVLMNGKDYRMNIQVFEPHNKPLDTYEEVIEVFKDYYKQAINVLERANNIE
EEECCCEEEEEEECCCCEEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCE
LDIWRKFDTSIINSLLKPDCLDKGQHIGNMGYRYNATLNVETCGTVTMVNSFAALKKLVY
EEEEHHHHHHHHHHHHCCCHHHCCCCCCCCCEEEEEEEEECCCCHHHHHHHHHHHHHHHH
DDKAFTIEEMKDAILNNFGFKDALEVGNYSMADQVKVDKTGKYDAIYKACLDAPKYGNND
CCCCCCHHHHHHHHHHCCCCHHHHHHCCCCCCCCEEECCCCCHHHHHHHHHCCCCCCCCC
LYADNILKNYEVWLSKVCEEAQSLYAKKMYPCQISVSTHGPQGAATLATPDGRLSGTTYS
CCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCEEEECCCCCCCCCCCC
DGSVSAYAGTDKNGVYALFESATIWDQAVVQNSQMNLKLHPTTIKGQQGTKKLLDLTRSY
CCCEEEECCCCCCCEEEEECCCHHHHHHHHCCCCCEEEECCCEECCCCHHHHHHHHHHHH
LRKGGFHIQYNVVDSETLKDAQKNPDNYRQLMVRVAGFTQYWCELGKPIQDEVIARTEYE
HHCCCCEEEEEECCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCC
GV
CC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA