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The map label for this gene is gatC [H]

Identifier: 126697609

GI number: 126697609

Start: 67656

End: 69005

Strand: Direct

Name: gatC [H]

Synonym: CD0043

Alternate gene names: 126697609

Gene position: 67656-69005 (Clockwise)

Preceding gene: 126697608

Following gene: 126697610

Centisome position: 1.58

GC content: 32.52

Gene sequence:

>1350_bases
ATGGAGATATTAAATTTCATTGTTGGTCTAGGTGCACAAGTAATGATGCCAATAATAATATGTATTTTTGGTTTGATATT
AGGTACAAAACTAGGAAAATCTTTAAGAGCTGGTTTAACTGTGGGAGTTGGGTTTATAGGTCTTAACACTATTATAGCTT
TGCTAACAGATAATTTAGGTCCAGCTACACAACAAATGGTTAAGAATTTAGGGCTAAGTTTATCAATAATAGATGTAGGA
TGGCCAGCAGCATCAGCTATAGCTTTTGCATCAACAGTAGGGGCTTTAATTATTCCAATAGGTCTTGTGGTAAATATAGT
TATGCTAATTACTAATACTACTCAAACTGTTGATGTAGACATATGGGATTACTGGCATTTTGCTTTTACAGGAGCTTTAG
TGGCAGGGGCTACTCAAAGTGTAATGTGGGGAGTATTTGCAGCAGTAGCAAATATGGTAATTGTATTGGTAATGGCAGAT
TTAACTGCTCCAGGTATAGAGGAATATTTAGGTATGCCAGGTATATCTCTTCCTCATGGATTTACACAGGCATTTGTTCC
AATTGCTATAGTAGTAAATAAATTATTAGACCTAATACCAGGTATAAATAAGATTGAGATAAATGCTGATACATTGCAGA
AAAAATTTGGATTATTTGGAGAACCTTTAATAATGGGGTCTGTAATAGGTGTAATAATTGGTATTGCTGCGAAATATGAT
ATAAAAGGAATATTACAATTAGGTGTAACTATGGGAGCTGTATTAATATTAATTCCAAAGATGGCAGCATTATTAATGGA
AGGATTATTACCAGTATCAGAAGCTGCACAAGAATTTATTGAGAAGAGATTTAAAAACAGAGGCAAGATTTATATAGGCT
TAGATTCAGCAGTAGGAATAGGTCATCCTGTTACATTATCAGTTGCACTAGTGTTGGTTCCTTTGACTATACTTATAGCA
GCTATATTGCCAGGAAATAAAGTTTTACCATTTGCAGATTTAGCAGTAATTCCATTTGCACTTGTATTAATCGTACCAAT
TACAAAGGGAAATGTGTTTAGAACATTAATAATAGGAATAATTATAATTACTTCTGGATTATTAATCGCAACTAACTTAG
CTCCATTATTTACCCAAATGGCTTTAAATGCTAGTTTTAAAATGCCTGAAGGAGCAACTATGATTTCAAGTATTTGTGAT
GGTGCGAATCCATTAAGTTGGGTATTTGTAAAAGTTATGAACTATAAAGTTATTGGAGGAGTAGTTTTTGGAGTTATAGC
TTTAGGAATGGCTATTTACAATAGGAATAGAATAATAAATGAAAATAAAAAGCTATCTATAGAAGAATAA

Upstream 100 bases:

>100_bases
GTATTAGAAGAGTTAGAATTATAATTAAAAAAATTAAGGAACATGGTCTCTAAAATCATAAGTTTTAGAGACTTAAAATT
AAATAATGGAGGGTCTTTAT

Downstream 100 bases:

>100_bases
GGTTAAAACAATTTTATTAAGGAGTGTATAGGTTATGAAAAAATATAAATATGATTCTAAAAGATACTTACTCAATGTTA
CAATACCAGGATTTTTTATG

Product: PTS system transporter subunit IIC

Products: galactitol-1-phosphate [Cytoplasm]; pyruvate [C]

Alternate protein names: EIIC-Gat; PTS system galactitol-specific EIIC component [H]

Number of amino acids: Translated: 449; Mature: 449

Protein sequence:

>449_residues
MEILNFIVGLGAQVMMPIIICIFGLILGTKLGKSLRAGLTVGVGFIGLNTIIALLTDNLGPATQQMVKNLGLSLSIIDVG
WPAASAIAFASTVGALIIPIGLVVNIVMLITNTTQTVDVDIWDYWHFAFTGALVAGATQSVMWGVFAAVANMVIVLVMAD
LTAPGIEEYLGMPGISLPHGFTQAFVPIAIVVNKLLDLIPGINKIEINADTLQKKFGLFGEPLIMGSVIGVIIGIAAKYD
IKGILQLGVTMGAVLILIPKMAALLMEGLLPVSEAAQEFIEKRFKNRGKIYIGLDSAVGIGHPVTLSVALVLVPLTILIA
AILPGNKVLPFADLAVIPFALVLIVPITKGNVFRTLIIGIIIITSGLLIATNLAPLFTQMALNASFKMPEGATMISSICD
GANPLSWVFVKVMNYKVIGGVVFGVIALGMAIYNRNRIINENKKLSIEE

Sequences:

>Translated_449_residues
MEILNFIVGLGAQVMMPIIICIFGLILGTKLGKSLRAGLTVGVGFIGLNTIIALLTDNLGPATQQMVKNLGLSLSIIDVG
WPAASAIAFASTVGALIIPIGLVVNIVMLITNTTQTVDVDIWDYWHFAFTGALVAGATQSVMWGVFAAVANMVIVLVMAD
LTAPGIEEYLGMPGISLPHGFTQAFVPIAIVVNKLLDLIPGINKIEINADTLQKKFGLFGEPLIMGSVIGVIIGIAAKYD
IKGILQLGVTMGAVLILIPKMAALLMEGLLPVSEAAQEFIEKRFKNRGKIYIGLDSAVGIGHPVTLSVALVLVPLTILIA
AILPGNKVLPFADLAVIPFALVLIVPITKGNVFRTLIIGIIIITSGLLIATNLAPLFTQMALNASFKMPEGATMISSICD
GANPLSWVFVKVMNYKVIGGVVFGVIALGMAIYNRNRIINENKKLSIEE
>Mature_449_residues
MEILNFIVGLGAQVMMPIIICIFGLILGTKLGKSLRAGLTVGVGFIGLNTIIALLTDNLGPATQQMVKNLGLSLSIIDVG
WPAASAIAFASTVGALIIPIGLVVNIVMLITNTTQTVDVDIWDYWHFAFTGALVAGATQSVMWGVFAAVANMVIVLVMAD
LTAPGIEEYLGMPGISLPHGFTQAFVPIAIVVNKLLDLIPGINKIEINADTLQKKFGLFGEPLIMGSVIGVIIGIAAKYD
IKGILQLGVTMGAVLILIPKMAALLMEGLLPVSEAAQEFIEKRFKNRGKIYIGLDSAVGIGHPVTLSVALVLVPLTILIA
AILPGNKVLPFADLAVIPFALVLIVPITKGNVFRTLIIGIIIITSGLLIATNLAPLFTQMALNASFKMPEGATMISSICD
GANPLSWVFVKVMNYKVIGGVVFGVIALGMAIYNRNRIINENKKLSIEE

Specific function: The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane. This system i

COG id: COG3775

COG function: function code G; Phosphotransferase system, galactitol-specific IIC component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PTS EIIC type-2 domain [H]

Homologues:

Organism=Escherichia coli, GI1788408, Length=451, Percent_Identity=41.2416851441242, Blast_Score=356, Evalue=2e-99,
Organism=Escherichia coli, GI1790758, Length=439, Percent_Identity=40.0911161731207, Blast_Score=332, Evalue=4e-92,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013853
- InterPro:   IPR013014
- InterPro:   IPR004703 [H]

Pfam domain/function: PF03611 EIIC-GAT [H]

EC number: NA

Molecular weight: Translated: 47445; Mature: 47445

Theoretical pI: Translated: 8.19; Mature: 8.19

Prosite motif: PS51104 PTS_EIIC_TYPE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
4.0 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHHHHHHHHHHCCCCEECCCCCCCCCC
>Mature Secondary Structure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HHHHHHHHHHHHHCCCCEECCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: phosphoenolpyruvate; galactitol [Periplasm] [C]

Specific reaction: phosphoenolpyruvate + galactitol [Periplasm] = galactitol-1-phosphate [Cytoplasm] + pyruvate [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]