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The map label for this gene is thrC [H]

Identifier: 126697244

GI number: 126697244

Start: 1640608

End: 1641711

Strand: Direct

Name: thrC [H]

Synonym: P9301_19061

Alternate gene names: 126697244

Gene position: 1640608-1641711 (Clockwise)

Preceding gene: 126697243

Following gene: NA

Centisome position: 99.92

GC content: 33.24

Gene sequence:

>1104_bases
ATGGTGTTATTAGATAAAATCAAAAATAAACTGCGTTTTAATTATAGAAAAAAAAGATGGCCTGGCCTTATAGAAGCTTA
TAAACAATATCTCCCAGTAACGAAGAAAACTCCTATTATTTCCCTCAATGAAGGAAATACACCACTGATCTTAAGCGAAT
TAATTAGCAACTTAATTGGAAATGGAACAAAAGTTTTTTTAAAATATGATGGCCTTAATCCAACAGGATCTTTTAAAGAT
CGTGGTATGACTATGGCAATTAGCAAAGCAAAAGAAGAAGGGCGTGAAGCAGTTATTTGTGCAAGCACTGGAAATACCTC
TGCTGCTGCTGCTGCATATGCTTCGAGAGGAGGATTAAAACCTTATGTATTAATACCAGAAGGATTTGTTGCACAAGGAA
AACTTGCTCAAGCATTAATGTATGGCGCTGAGATAATATCTATTAATGGAAACTTTGATAAGGCCCTTGAAATTGTTAGA
GATTTATCCTCAGAACATCCAGTAGAACTTGTTAATTCGGTTAATCCATATCGAATACAAGGACAAAAGACAGCAGCTTT
TGAAATAGTTGATGACTTAGGTTATGCTCCTGATTGGCTTTGTATTCCAATGGGCAATGCAGGAAATATAACTGCTTATT
GGATGGGATTTAAAGAGTATTCAAAAATTAAAAAAAATTTGAAATTACCAATAATGATGGGTTTTCAATCCGAAGGCTCT
GCTCCATTAGTAAAAAATATAATAGTTAAAGATCCGGAAACAATTGCAACTGCAATCAGAATTGGGAATCCTGTAAATAG
AGAAAAAGCAAAAAAAGTAAGAAAGGAGAGTAAAGGAGATTTTCAGTCAGTTACAGATAAAGAAATAATCGATGCTTATA
AAATCCTTGCCAAAGAGGGGGTTTTTTGTGAACCTGCCAGTGCAGCATCAGTTGCTGGACTGATTAAAAATAAAAATAGA
ATTCAGAAAGAATCGACTATTGTTTGTGTTCTGACTGGAAATGGCTTGAAAGATCCTGATTGCGCTATTAAAAATAATGA
TGCTATTTTTAGGAAAAATATTGAACCTTCATTAAAAAATATAACTAAAATCTTAGGATATTAA

Upstream 100 bases:

>100_bases
CGCTTTGAGCAAAGTTATGAATAAAGTAGAATCGATTTCAGAACTATTAACCTTTTTTACCAATTCCCCTTTAGAAAAAA
TCAAAACAAATTAAACAACC

Downstream 100 bases:

>100_bases
AATCCAAAAAAAATATTGTCTGTGGAAATCAATTAAAAACAAACCTCATTTGTTGAAAAGTACATAACAAGAAATTCTAT
TTGTTGAATAAATTTAAAAT

Product: threonine synthase

Products: NA

Alternate protein names: TS [H]

Number of amino acids: Translated: 367; Mature: 367

Protein sequence:

>367_residues
MVLLDKIKNKLRFNYRKKRWPGLIEAYKQYLPVTKKTPIISLNEGNTPLILSELISNLIGNGTKVFLKYDGLNPTGSFKD
RGMTMAISKAKEEGREAVICASTGNTSAAAAAYASRGGLKPYVLIPEGFVAQGKLAQALMYGAEIISINGNFDKALEIVR
DLSSEHPVELVNSVNPYRIQGQKTAAFEIVDDLGYAPDWLCIPMGNAGNITAYWMGFKEYSKIKKNLKLPIMMGFQSEGS
APLVKNIIVKDPETIATAIRIGNPVNREKAKKVRKESKGDFQSVTDKEIIDAYKILAKEGVFCEPASAASVAGLIKNKNR
IQKESTIVCVLTGNGLKDPDCAIKNNDAIFRKNIEPSLKNITKILGY

Sequences:

>Translated_367_residues
MVLLDKIKNKLRFNYRKKRWPGLIEAYKQYLPVTKKTPIISLNEGNTPLILSELISNLIGNGTKVFLKYDGLNPTGSFKD
RGMTMAISKAKEEGREAVICASTGNTSAAAAAYASRGGLKPYVLIPEGFVAQGKLAQALMYGAEIISINGNFDKALEIVR
DLSSEHPVELVNSVNPYRIQGQKTAAFEIVDDLGYAPDWLCIPMGNAGNITAYWMGFKEYSKIKKNLKLPIMMGFQSEGS
APLVKNIIVKDPETIATAIRIGNPVNREKAKKVRKESKGDFQSVTDKEIIDAYKILAKEGVFCEPASAASVAGLIKNKNR
IQKESTIVCVLTGNGLKDPDCAIKNNDAIFRKNIEPSLKNITKILGY
>Mature_367_residues
MVLLDKIKNKLRFNYRKKRWPGLIEAYKQYLPVTKKTPIISLNEGNTPLILSELISNLIGNGTKVFLKYDGLNPTGSFKD
RGMTMAISKAKEEGREAVICASTGNTSAAAAAYASRGGLKPYVLIPEGFVAQGKLAQALMYGAEIISINGNFDKALEIVR
DLSSEHPVELVNSVNPYRIQGQKTAAFEIVDDLGYAPDWLCIPMGNAGNITAYWMGFKEYSKIKKNLKLPIMMGFQSEGS
APLVKNIIVKDPETIATAIRIGNPVNREKAKKVRKESKGDFQSVTDKEIIDAYKILAKEGVFCEPASAASVAGLIKNKNR
IQKESTIVCVLTGNGLKDPDCAIKNNDAIFRKNIEPSLKNITKILGY

Specific function: Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine [H]

COG id: COG0498

COG function: function code E; Threonine synthase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the threonine synthase family [H]

Homologues:

Organism=Escherichia coli, GI2367138, Length=287, Percent_Identity=27.1777003484321, Blast_Score=69, Evalue=6e-13,
Organism=Caenorhabditis elegans, GI17508781, Length=313, Percent_Identity=26.517571884984, Blast_Score=74, Evalue=9e-14,
Organism=Saccharomyces cerevisiae, GI6322631, Length=286, Percent_Identity=27.2727272727273, Blast_Score=74, Evalue=3e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001926
- InterPro:   IPR000634
- InterPro:   IPR004450 [H]

Pfam domain/function: PF00291 PALP [H]

EC number: =4.2.3.1 [H]

Molecular weight: Translated: 40267; Mature: 40267

Theoretical pI: Translated: 9.94; Mature: 9.94

Prosite motif: PS00165 DEHYDRATASE_SER_THR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVLLDKIKNKLRFNYRKKRWPGLIEAYKQYLPVTKKTPIISLNEGNTPLILSELISNLIG
CEEHHHHHHHHHCCHHHHCCCHHHHHHHHHCCCCCCCCEEEECCCCCCCHHHHHHHHHHC
NGTKVFLKYDGLNPTGSFKDRGMTMAISKAKEEGREAVICASTGNTSAAAAAYASRGGLK
CCEEEEEEECCCCCCCCCCCCCEEEEEHHHHHCCCEEEEEEECCCCHHHHHHHHHCCCCC
PYVLIPEGFVAQGKLAQALMYGAEIISINGNFDKALEIVRDLSSEHPVELVNSVNPYRIQ
CEEECCCCCCCCHHHHHHHHHCCEEEEECCCHHHHHHHHHHCCCCCCHHHHHCCCCEEEC
GQKTAAFEIVDDLGYAPDWLCIPMGNAGNITAYWMGFKEYSKIKKNLKLPIMMGFQSEGS
CCCCHHHHHHHHCCCCCCEEEEECCCCCCEEEEEECHHHHHHHHHCCCCEEEEECCCCCC
APLVKNIIVKDPETIATAIRIGNPVNREKAKKVRKESKGDFQSVTDKEIIDAYKILAKEG
CCHHHHHHCCCCHHHHHHHHCCCCCCHHHHHHHHHHCCCCHHHCCHHHHHHHHHHHHHCC
VFCEPASAASVAGLIKNKNRIQKESTIVCVLTGNGLKDPDCAIKNNDAIFRKNIEPSLKN
CCCCCCCHHHHHHHHHCHHHCCCCCEEEEEEECCCCCCCCCEECCCCCEEECCCCHHHHH
ITKILGY
HHHHHCC
>Mature Secondary Structure
MVLLDKIKNKLRFNYRKKRWPGLIEAYKQYLPVTKKTPIISLNEGNTPLILSELISNLIG
CEEHHHHHHHHHCCHHHHCCCHHHHHHHHHCCCCCCCCEEEECCCCCCCHHHHHHHHHHC
NGTKVFLKYDGLNPTGSFKDRGMTMAISKAKEEGREAVICASTGNTSAAAAAYASRGGLK
CCEEEEEEECCCCCCCCCCCCCEEEEEHHHHHCCCEEEEEEECCCCHHHHHHHHHCCCCC
PYVLIPEGFVAQGKLAQALMYGAEIISINGNFDKALEIVRDLSSEHPVELVNSVNPYRIQ
CEEECCCCCCCCHHHHHHHHHCCEEEEECCCHHHHHHHHHHCCCCCCHHHHHCCCCEEEC
GQKTAAFEIVDDLGYAPDWLCIPMGNAGNITAYWMGFKEYSKIKKNLKLPIMMGFQSEGS
CCCCHHHHHHHHCCCCCCEEEEECCCCCCEEEEEECHHHHHHHHHCCCCEEEEECCCCCC
APLVKNIIVKDPETIATAIRIGNPVNREKAKKVRKESKGDFQSVTDKEIIDAYKILAKEG
CCHHHHHHCCCCHHHHHHHHCCCCCCHHHHHHHHHHCCCCHHHCCHHHHHHHHHHHHHCC
VFCEPASAASVAGLIKNKNRIQKESTIVCVLTGNGLKDPDCAIKNNDAIFRKNIEPSLKN
CCCCCCCHHHHHHHHHCHHHCCCCCEEEEEEECCCCCCCCCEECCCCCEEECCCCHHHHH
ITKILGY
HHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8905231 [H]