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The map label for this gene is glmS [H]

Identifier: 126697137

GI number: 126697137

Start: 1520256

End: 1522151

Strand: Reverse

Name: glmS [H]

Synonym: P9301_17991

Alternate gene names: 126697137

Gene position: 1522151-1520256 (Counterclockwise)

Preceding gene: 126697138

Following gene: 126697135

Centisome position: 92.71

GC content: 32.23

Gene sequence:

>1896_bases
ATGTGTGGAATAGTTGCTGTAACTGGATACAAAAAAGCTTTGCCATTATTAATAAATGGTTTAGAAAAACTTGAATACAG
AGGTTATGATTCTGCAGGTATTGCAATAATAAATTCCGAAACAAATTTTATTTCTTGTAATAAAGCAAAAGGAAAACTCA
AGAATTTAATAAGTAATCTTAATGACCATAATATTCCTGGAACTGTTGGAATAGGTCATACCAGATGGGCAACTCATGGC
AAGCCAGAGGTTAAAAATGCACATCCTCATACAGATAGTTCAGGAAATATAGCAGTTGTTCAAAATGGTATTATTGAAAA
TTTCCAAGATTTAAAAAATAAATTAGAGGAAGAGGGTATTATTTTTAATTCTGATACAGATACCGAGGTGATTCCTCATC
TAATTCAAAGAGAGTTAAATACATTAAATAAACTTAATCTTGAGAATAATGGTTCAACATTATTAGTAGCTGTAAGAAAT
GTCATATCTGATTTAGAAGGATCTTATGCTTTAGCAGTTTTATGGTCTGGTGCTCCAACCTCTTTGGTAGTTGCAAGAAG
ACAAGCGCCTTTGATTATAGGTTTGGGTGAAGGAGAATTTATTTGTGCTAGTGATACGCCTGCCATTGCGAATTTTACGA
ATATTATTTTGCCTATGGAGGATGAAGAAATAGCTTTGTTGACTCCGCTTGGAATTGAAATATATGACTCAAGCAACGAG
AGACAATATCGAAATCCAATTTCTTTAAAGGTCTCAGAGCAAATAATGGATAAGATGAATTTCAAACACTATATGTTAAA
AGAGATATATGATCAGCCACAGACTGCAAAAAATTGGTTGGAAAATTATTTAATTAAGAACTTAGATAATGGTCAATATC
AAATCAAATATCCATTTGATACAGAGTTTTTTGAATCAATAGAAAGAATTGAAATTATTGCCTGTGGTACAAGTAAACAT
GCTGCAATGGTTGGAAGTTTTTTATTAGAACAATTCTCAGGTATCCCTACAAATGTTTTTTATGCAAGCGAATTTCGATA
TTCTCCCCCTCCACTATTGCCAAATACATTAACTATTGGAGTCACTCAATCTGGAGAAACTGCTGATACAATTGCGGCTA
TCGATATGGAAATTAAAAGACGTTCTTCAATTGAAGATAAAAAATTCAAACCCAATCTTATTGCAATAACAAATAGGAAA
GAGAGTTCCATCGGAAGGCAGGTTTCTAATATTATTGATATCTGTGCAGGAATAGAAGTTGGAGTTGCAGCAACAAAAAC
TTTTTTTGCTCAGTTACTTTCGTTTTATGGATTAGCTATAAAATTTGCTCAAATAAAAGGTAATCAAAGTCCTGACGAAA
TAGGTAAATTAATAAACGAACTTATAAAACTTCCGCCATTACTGGAAGATCTCTTACACAAACATAATAAATCGTCAGAA
AAGCTAGCGCATGACTTTTTTAATATAAAAGATGTTATTTTTTTAGGAAGAGGAATAAATTATCCAATTGCTCTTGAAGG
TGCTTTAAAACTTAAAGAAATTAGTTATATTCATGCAGCTGGATATCCTGCTGGGGAAATGAAACATGGTCCAATAGCTT
TATTAGATAAAAAAGTACCTGTAATTTCTATTGCCTCTCCTGGTGAAGTTTTTGATAAAGTTATCAGTAATGCTCAAGAA
GCAAAAGCTAGAGATTCATATTTGATTGGGATTGCTCCTGAATGTAATGGAACTGAAATCTTTGATTATTTAATGAAAGT
TCCTTCTTCTAATGAATTGATTTCACCTCTACTTAATATATTGCCTTTACAATTATTGAGTTACCATATTGCAGCTCACA
GGGGACTTGACGTGGATCAACCAAGAAATTTAGCTAAAAGTGTAACTGTGGAATAA

Upstream 100 bases:

>100_bases
TGGGTTTAGCATATTAACTCTTTTTATAGTGCAGTTTTAAGAGAGTCCATTTTTTAGTAAATACGCATTTTATTTCAATA
TAATTGAAAAAAAAATTCGT

Downstream 100 bases:

>100_bases
TTAGCTTCTTGCAAATTTTGATATTTTTAATTTAAAGCTCTAAAAGTCCATTTGGAGGATTGATGATTACAAATTGATTT
TTTATATCTACTAATGGCAC

Product: glucosamine--fructose-6-phosphate aminotransferase

Products: NA

Alternate protein names: D-fructose-6-phosphate amidotransferase; GFAT; Glucosamine-6-phosphate synthase; Hexosephosphate aminotransferase; L-glutamine-D-fructose-6-phosphate amidotransferase [H]

Number of amino acids: Translated: 631; Mature: 631

Protein sequence:

>631_residues
MCGIVAVTGYKKALPLLINGLEKLEYRGYDSAGIAIINSETNFISCNKAKGKLKNLISNLNDHNIPGTVGIGHTRWATHG
KPEVKNAHPHTDSSGNIAVVQNGIIENFQDLKNKLEEEGIIFNSDTDTEVIPHLIQRELNTLNKLNLENNGSTLLVAVRN
VISDLEGSYALAVLWSGAPTSLVVARRQAPLIIGLGEGEFICASDTPAIANFTNIILPMEDEEIALLTPLGIEIYDSSNE
RQYRNPISLKVSEQIMDKMNFKHYMLKEIYDQPQTAKNWLENYLIKNLDNGQYQIKYPFDTEFFESIERIEIIACGTSKH
AAMVGSFLLEQFSGIPTNVFYASEFRYSPPPLLPNTLTIGVTQSGETADTIAAIDMEIKRRSSIEDKKFKPNLIAITNRK
ESSIGRQVSNIIDICAGIEVGVAATKTFFAQLLSFYGLAIKFAQIKGNQSPDEIGKLINELIKLPPLLEDLLHKHNKSSE
KLAHDFFNIKDVIFLGRGINYPIALEGALKLKEISYIHAAGYPAGEMKHGPIALLDKKVPVISIASPGEVFDKVISNAQE
AKARDSYLIGIAPECNGTEIFDYLMKVPSSNELISPLLNILPLQLLSYHIAAHRGLDVDQPRNLAKSVTVE

Sequences:

>Translated_631_residues
MCGIVAVTGYKKALPLLINGLEKLEYRGYDSAGIAIINSETNFISCNKAKGKLKNLISNLNDHNIPGTVGIGHTRWATHG
KPEVKNAHPHTDSSGNIAVVQNGIIENFQDLKNKLEEEGIIFNSDTDTEVIPHLIQRELNTLNKLNLENNGSTLLVAVRN
VISDLEGSYALAVLWSGAPTSLVVARRQAPLIIGLGEGEFICASDTPAIANFTNIILPMEDEEIALLTPLGIEIYDSSNE
RQYRNPISLKVSEQIMDKMNFKHYMLKEIYDQPQTAKNWLENYLIKNLDNGQYQIKYPFDTEFFESIERIEIIACGTSKH
AAMVGSFLLEQFSGIPTNVFYASEFRYSPPPLLPNTLTIGVTQSGETADTIAAIDMEIKRRSSIEDKKFKPNLIAITNRK
ESSIGRQVSNIIDICAGIEVGVAATKTFFAQLLSFYGLAIKFAQIKGNQSPDEIGKLINELIKLPPLLEDLLHKHNKSSE
KLAHDFFNIKDVIFLGRGINYPIALEGALKLKEISYIHAAGYPAGEMKHGPIALLDKKVPVISIASPGEVFDKVISNAQE
AKARDSYLIGIAPECNGTEIFDYLMKVPSSNELISPLLNILPLQLLSYHIAAHRGLDVDQPRNLAKSVTVE
>Mature_631_residues
MCGIVAVTGYKKALPLLINGLEKLEYRGYDSAGIAIINSETNFISCNKAKGKLKNLISNLNDHNIPGTVGIGHTRWATHG
KPEVKNAHPHTDSSGNIAVVQNGIIENFQDLKNKLEEEGIIFNSDTDTEVIPHLIQRELNTLNKLNLENNGSTLLVAVRN
VISDLEGSYALAVLWSGAPTSLVVARRQAPLIIGLGEGEFICASDTPAIANFTNIILPMEDEEIALLTPLGIEIYDSSNE
RQYRNPISLKVSEQIMDKMNFKHYMLKEIYDQPQTAKNWLENYLIKNLDNGQYQIKYPFDTEFFESIERIEIIACGTSKH
AAMVGSFLLEQFSGIPTNVFYASEFRYSPPPLLPNTLTIGVTQSGETADTIAAIDMEIKRRSSIEDKKFKPNLIAITNRK
ESSIGRQVSNIIDICAGIEVGVAATKTFFAQLLSFYGLAIKFAQIKGNQSPDEIGKLINELIKLPPLLEDLLHKHNKSSE
KLAHDFFNIKDVIFLGRGINYPIALEGALKLKEISYIHAAGYPAGEMKHGPIALLDKKVPVISIASPGEVFDKVISNAQE
AKARDSYLIGIAPECNGTEIFDYLMKVPSSNELISPLLNILPLQLLSYHIAAHRGLDVDQPRNLAKSVTVE

Specific function: Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source [H]

COG id: COG0449

COG function: function code M; Glucosamine 6-phosphate synthetase, contains amidotransferase and phosphosugar isomerase domains

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 SIS domains [H]

Homologues:

Organism=Homo sapiens, GI4826742, Length=709, Percent_Identity=33.8504936530324, Blast_Score=347, Evalue=3e-95,
Organism=Homo sapiens, GI205277386, Length=703, Percent_Identity=33.5704125177809, Blast_Score=340, Evalue=3e-93,
Organism=Escherichia coli, GI1790167, Length=635, Percent_Identity=41.8897637795276, Blast_Score=456, Evalue=1e-129,
Organism=Escherichia coli, GI1788651, Length=220, Percent_Identity=28.1818181818182, Blast_Score=81, Evalue=2e-16,
Organism=Escherichia coli, GI87082251, Length=320, Percent_Identity=23.125, Blast_Score=75, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI17539970, Length=448, Percent_Identity=34.375, Blast_Score=235, Evalue=5e-62,
Organism=Caenorhabditis elegans, GI17532897, Length=448, Percent_Identity=35.0446428571429, Blast_Score=233, Evalue=2e-61,
Organism=Caenorhabditis elegans, GI17532899, Length=449, Percent_Identity=34.9665924276169, Blast_Score=233, Evalue=2e-61,
Organism=Caenorhabditis elegans, GI17554892, Length=250, Percent_Identity=27.6, Blast_Score=66, Evalue=7e-11,
Organism=Saccharomyces cerevisiae, GI6322745, Length=446, Percent_Identity=33.1838565022422, Blast_Score=226, Evalue=1e-59,
Organism=Saccharomyces cerevisiae, GI6323731, Length=458, Percent_Identity=27.7292576419214, Blast_Score=150, Evalue=7e-37,
Organism=Saccharomyces cerevisiae, GI6323730, Length=211, Percent_Identity=39.8104265402844, Blast_Score=125, Evalue=2e-29,
Organism=Saccharomyces cerevisiae, GI6323958, Length=182, Percent_Identity=28.5714285714286, Blast_Score=74, Evalue=6e-14,
Organism=Drosophila melanogaster, GI21357745, Length=714, Percent_Identity=34.3137254901961, Blast_Score=363, Evalue=1e-100,
Organism=Drosophila melanogaster, GI24659598, Length=204, Percent_Identity=28.921568627451, Blast_Score=74, Evalue=3e-13,
Organism=Drosophila melanogaster, GI24659604, Length=184, Percent_Identity=29.3478260869565, Blast_Score=73, Evalue=5e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000583
- InterPro:   IPR017932
- InterPro:   IPR005855
- InterPro:   IPR001347 [H]

Pfam domain/function: PF00310 GATase_2; PF01380 SIS [H]

EC number: =2.6.1.16 [H]

Molecular weight: Translated: 69665; Mature: 69665

Theoretical pI: Translated: 5.90; Mature: 5.90

Prosite motif: PS00443 GATASE_TYPE_II

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MCGIVAVTGYKKALPLLINGLEKLEYRGYDSAGIAIINSETNFISCNKAKGKLKNLISNL
CCCEEEECCHHHHHHHHHHHHHHHHCCCCCCCCEEEEECCCCEEEECCHHHHHHHHHHCC
NDHNIPGTVGIGHTRWATHGKPEVKNAHPHTDSSGNIAVVQNGIIENFQDLKNKLEEEGI
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEECCHHHHHHHHHHHHHHCCE
IFNSDTDTEVIPHLIQRELNTLNKLNLENNGSTLLVAVRNVISDLEGSYALAVLWSGAPT
EECCCCCHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEHHHHHHHCCCCEEEEEEECCCCC
SLVVARRQAPLIIGLGEGEFICASDTPAIANFTNIILPMEDEEIALLTPLGIEIYDSSNE
EEEEEECCCCEEEECCCCCEEEECCCCCHHCCEEEEEECCCCCEEEEECCCEEEEECCCC
RQYRNPISLKVSEQIMDKMNFKHYMLKEIYDQPQTAKNWLENYLIKNLDNGQYQIKYPFD
CCCCCCCCEEEHHHHHHHHCHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCEEEEECCCC
TEFFESIERIEIIACGTSKHAAMVGSFLLEQFSGIPTNVFYASEFRYSPPPLLPNTLTIG
HHHHHHHHHEEEEEECCCHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCCCCCCEEEE
VTQSGETADTIAAIDMEIKRRSSIEDKKFKPNLIAITNRKESSIGRQVSNIIDICAGIEV
EECCCCCHHHEEEHHHHHHHHCCCCCCCCCCCEEEEECCCHHHHHHHHHHHHHHHCCCCC
GVAATKTFFAQLLSFYGLAIKFAQIKGNQSPDEIGKLINELIKLPPLLEDLLHKHNKSSE
CHHHHHHHHHHHHHHHHHHEEEEEECCCCCHHHHHHHHHHHHHCCHHHHHHHHHCCCCHH
KLAHDFFNIKDVIFLGRGINYPIALEGALKLKEISYIHAAGYPAGEMKHGPIALLDKKVP
HHHHHHHCHHEEEEECCCCCCCEEECCCEEEHHEEEEEECCCCCCCCCCCCEEEEECCCC
VISIASPGEVFDKVISNAQEAKARDSYLIGIAPECNGTEIFDYLMKVPSSNELISPLLNI
EEEECCCHHHHHHHHCCHHHHHCCCCEEEEECCCCCCHHHHHHHHHCCCCCHHHHHHHHH
LPLQLLSYHIAAHRGLDVDQPRNLAKSVTVE
HHHHHHHHHHHHHCCCCCCCCHHHHHHCCCC
>Mature Secondary Structure
MCGIVAVTGYKKALPLLINGLEKLEYRGYDSAGIAIINSETNFISCNKAKGKLKNLISNL
CCCEEEECCHHHHHHHHHHHHHHHHCCCCCCCCEEEEECCCCEEEECCHHHHHHHHHHCC
NDHNIPGTVGIGHTRWATHGKPEVKNAHPHTDSSGNIAVVQNGIIENFQDLKNKLEEEGI
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEECCHHHHHHHHHHHHHHCCE
IFNSDTDTEVIPHLIQRELNTLNKLNLENNGSTLLVAVRNVISDLEGSYALAVLWSGAPT
EECCCCCHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEHHHHHHHCCCCEEEEEEECCCCC
SLVVARRQAPLIIGLGEGEFICASDTPAIANFTNIILPMEDEEIALLTPLGIEIYDSSNE
EEEEEECCCCEEEECCCCCEEEECCCCCHHCCEEEEEECCCCCEEEEECCCEEEEECCCC
RQYRNPISLKVSEQIMDKMNFKHYMLKEIYDQPQTAKNWLENYLIKNLDNGQYQIKYPFD
CCCCCCCCEEEHHHHHHHHCHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCEEEEECCCC
TEFFESIERIEIIACGTSKHAAMVGSFLLEQFSGIPTNVFYASEFRYSPPPLLPNTLTIG
HHHHHHHHHEEEEEECCCHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCCCCCCEEEE
VTQSGETADTIAAIDMEIKRRSSIEDKKFKPNLIAITNRKESSIGRQVSNIIDICAGIEV
EECCCCCHHHEEEHHHHHHHHCCCCCCCCCCCEEEEECCCHHHHHHHHHHHHHHHCCCCC
GVAATKTFFAQLLSFYGLAIKFAQIKGNQSPDEIGKLINELIKLPPLLEDLLHKHNKSSE
CHHHHHHHHHHHHHHHHHHEEEEEECCCCCHHHHHHHHHHHHHCCHHHHHHHHHCCCCHH
KLAHDFFNIKDVIFLGRGINYPIALEGALKLKEISYIHAAGYPAGEMKHGPIALLDKKVP
HHHHHHHCHHEEEEECCCCCCCEEECCCEEEHHEEEEEECCCCCCCCCCCCEEEEECCCC
VISIASPGEVFDKVISNAQEAKARDSYLIGIAPECNGTEIFDYLMKVPSSNELISPLLNI
EEEECCCHHHHHHHHCCHHHHHCCCCEEEEECCCCCCHHHHHHHHHCCCCCHHHHHHHHH
LPLQLLSYHIAAHRGLDVDQPRNLAKSVTVE
HHHHHHHHHHHHHCCCCCCCCHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12240834 [H]