| Definition | Prochlorococcus marinus str. MIT 9301, complete genome. |
|---|---|
| Accession | NC_009091 |
| Length | 1,641,879 |
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The map label for this gene is hisD [H]
Identifier: 126697017
GI number: 126697017
Start: 1410728
End: 1412014
Strand: Direct
Name: hisD [H]
Synonym: P9301_16791
Alternate gene names: 126697017
Gene position: 1410728-1412014 (Clockwise)
Preceding gene: 126697003
Following gene: 126697020
Centisome position: 85.92
GC content: 33.33
Gene sequence:
>1287_bases ATGAAGATAATAAATAATAAAACAGAAGCTATTGAAGAATTGAAGAGGATTTCTACCCGAACTAATTCAGAAAATAATAA TAAGATAAATAAAATTGTTGAAGAAATTCTTCAAGAGGTAAAAATTTCTGGAGATAACGCAGTTGAAAAATATACCAAAA AATTTGATGGTTTCGATCCTAACCCTATGCAAGTGAATGCGGATCAAATAAAGAATGCATGGGATGAAATTGATAACAAT TTGAAACGCTCACTTGAGGAGGCTCACAAAAGAATTCAAAAATTCCATGAAAAAGAAATTCCTCAATCTTTCACGATAAA AGGTGAATATGGTGATATTGTCCAAAGAAGATGGAAACCAGTTAAAAATGCAGGTATTTATATTCCTGGAGGAAGAGCTG CTTATCCAAGTACTGTATTAATGAATGCAATTCCTGCAAAAGTAGCAGGAGTAGCTGAAATTATAATGGTATCTCCTGGA AATAAAGAAGGGGAAATAAACAAAACTGTTTTAGCTGCAGCTCACTTATCAGGTATCAATAAAGTATTTAGAATTGGAGG AGCTCAAGCGATTGGTGCATTAGCATTTGGCACAAATCAAATCAACAAAGTTGATGTTATATCAGGTCCAGGGAATATAT ATGTTACAACTGCAAAAAAACTAATTTATGGCTCAACAGGAATTGATTCATTAGCTGGTCCAAGTGAAATATTAATCATT GCAGATGAAACAGCTCAAAGCACTCATATAGCATCTGATCTACTAGCGCAAGCAGAACATGATCCTTTGGCTTCATCAAT ACTACTAACTACATCAAAGAACCAGGCAAAAGAAGTTTTAGAAGAACTTTATAAAAAAATTGAGGACCATCCAAGAAAAG AAATTTGCATGCAATCAATCAACAATTGGGGTTCAATTGTGATTTGCGAGAATTCTGAACAATGTGTTGAACTAAGCAAT AACTTTGCCCCTGAACACCTAGAAATTCTTACTGTAGATCCAAAAAAAATTCTTGCAGGTATAGAGAATGCAGGAGCAAT TTTTTTAGGAAAATGGACTCCAGAAGCTGTTGGAGATTATCTTGCTGGACCAAATCATACTTTACCCACATCAGGTAATT CTAGATTTAGCGGTTCTTTAGGGGTTGAAACTTTTATGAAAAATTCTTCAATAATAGAATTTAATGAAGAAAGTTTAAAA GTTAATAGCCTTGATATTATTAATCTAGCTAAAAGTGAGGGCTTGCATAGTCACGCTAACTCAGTACAAATAAGATTTGA AGATTAG
Upstream 100 bases:
>100_bases TTTATATCATAACAAATAAATCGACAACTAATCAATCATATATAATTTAGAAAATTATTAAATTGGGTTTTGAGCCTTTC AATTTGAAAAAATTAAGCAT
Downstream 100 bases:
>100_bases CTAGCTCTTGATGGTGAGTAAACCACTGGAGTATTGTTTTCAATTTTACCAACTAATACTTTATCTGTAAGATCAACGAA TAATCCATTTTCTAATACTC
Product: histidinol dehydrogenase
Products: NA
Alternate protein names: HDH [H]
Number of amino acids: Translated: 428; Mature: 428
Protein sequence:
>428_residues MKIINNKTEAIEELKRISTRTNSENNNKINKIVEEILQEVKISGDNAVEKYTKKFDGFDPNPMQVNADQIKNAWDEIDNN LKRSLEEAHKRIQKFHEKEIPQSFTIKGEYGDIVQRRWKPVKNAGIYIPGGRAAYPSTVLMNAIPAKVAGVAEIIMVSPG NKEGEINKTVLAAAHLSGINKVFRIGGAQAIGALAFGTNQINKVDVISGPGNIYVTTAKKLIYGSTGIDSLAGPSEILII ADETAQSTHIASDLLAQAEHDPLASSILLTTSKNQAKEVLEELYKKIEDHPRKEICMQSINNWGSIVICENSEQCVELSN NFAPEHLEILTVDPKKILAGIENAGAIFLGKWTPEAVGDYLAGPNHTLPTSGNSRFSGSLGVETFMKNSSIIEFNEESLK VNSLDIINLAKSEGLHSHANSVQIRFED
Sequences:
>Translated_428_residues MKIINNKTEAIEELKRISTRTNSENNNKINKIVEEILQEVKISGDNAVEKYTKKFDGFDPNPMQVNADQIKNAWDEIDNN LKRSLEEAHKRIQKFHEKEIPQSFTIKGEYGDIVQRRWKPVKNAGIYIPGGRAAYPSTVLMNAIPAKVAGVAEIIMVSPG NKEGEINKTVLAAAHLSGINKVFRIGGAQAIGALAFGTNQINKVDVISGPGNIYVTTAKKLIYGSTGIDSLAGPSEILII ADETAQSTHIASDLLAQAEHDPLASSILLTTSKNQAKEVLEELYKKIEDHPRKEICMQSINNWGSIVICENSEQCVELSN NFAPEHLEILTVDPKKILAGIENAGAIFLGKWTPEAVGDYLAGPNHTLPTSGNSRFSGSLGVETFMKNSSIIEFNEESLK VNSLDIINLAKSEGLHSHANSVQIRFED >Mature_428_residues MKIINNKTEAIEELKRISTRTNSENNNKINKIVEEILQEVKISGDNAVEKYTKKFDGFDPNPMQVNADQIKNAWDEIDNN LKRSLEEAHKRIQKFHEKEIPQSFTIKGEYGDIVQRRWKPVKNAGIYIPGGRAAYPSTVLMNAIPAKVAGVAEIIMVSPG NKEGEINKTVLAAAHLSGINKVFRIGGAQAIGALAFGTNQINKVDVISGPGNIYVTTAKKLIYGSTGIDSLAGPSEILII ADETAQSTHIASDLLAQAEHDPLASSILLTTSKNQAKEVLEELYKKIEDHPRKEICMQSINNWGSIVICENSEQCVELSN NFAPEHLEILTVDPKKILAGIENAGAIFLGKWTPEAVGDYLAGPNHTLPTSGNSRFSGSLGVETFMKNSSIIEFNEESLK VNSLDIINLAKSEGLHSHANSVQIRFED
Specific function: Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine [H]
COG id: COG0141
COG function: function code E; Histidinol dehydrogenase
Gene ontology:
Cell location: Cytoplasm [C]
Metaboloic importance: Non_Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Belongs to the histidinol dehydrogenase family [H]
Homologues:
Organism=Escherichia coli, GI1788331, Length=426, Percent_Identity=38.7323943661972, Blast_Score=309, Evalue=2e-85, Organism=Saccharomyces cerevisiae, GI6319819, Length=417, Percent_Identity=35.9712230215827, Blast_Score=265, Evalue=9e-72,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR016161 - InterPro: IPR022695 - InterPro: IPR001692 - InterPro: IPR012131 [H]
Pfam domain/function: PF00815 Histidinol_dh [H]
EC number: =1.1.1.23 [H]
Molecular weight: Translated: 46881; Mature: 46881
Theoretical pI: Translated: 5.85; Mature: 5.85
Prosite motif: PS00611 HISOL_DEHYDROGENASE
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.7 %Cys (Translated Protein) 1.4 %Met (Translated Protein) 2.1 %Cys+Met (Translated Protein) 0.7 %Cys (Mature Protein) 1.4 %Met (Mature Protein) 2.1 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MKIINNKTEAIEELKRISTRTNSENNNKINKIVEEILQEVKISGDNAVEKYTKKFDGFDP CCCCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCC NPMQVNADQIKNAWDEIDNNLKRSLEEAHKRIQKFHEKEIPQSFTIKGEYGDIVQRRWKP CCCEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCHHHHHHHHCCC VKNAGIYIPGGRAAYPSTVLMNAIPAKVAGVAEIIMVSPGNKEGEINKTVLAAAHLSGIN CCCCCEECCCCCCCCCHHHHHHHHHHHHHCCEEEEEECCCCCCCCCHHHHHHHHHHHHHH KVFRIGGAQAIGALAFGTNQINKVDVISGPGNIYVTTAKKLIYGSTGIDSLAGPSEILII HHHHCCCHHHHHHHEECCCCCCEEEEEECCCCEEEEEEEEEEECCCCCCCCCCCCEEEEE ADETAQSTHIASDLLAQAEHDPLASSILLTTSKNQAKEVLEELYKKIEDHPRKEICMQSI ECCCCCHHHHHHHHHHHCCCCCCCCEEEEECCCHHHHHHHHHHHHHHHCCCHHHHHHHHH NNWGSIVICENSEQCVELSNNFAPEHLEILTVDPKKILAGIENAGAIFLGKWTPEAVGDY CCCCCEEEECCCHHHHHHHCCCCCCCEEEEEECHHHHHHCCCCCCEEEEECCCHHHHHHH LAGPNHTLPTSGNSRFSGSLGVETFMKNSSIIEFNEESLKVNSLDIINLAKSEGLHSHAN HCCCCCCCCCCCCCCCCCCCCHHHHHCCCCEEEECCCCEEECCEEEEEEHHHCCCCCCCC SVQIRFED EEEEEECC >Mature Secondary Structure MKIINNKTEAIEELKRISTRTNSENNNKINKIVEEILQEVKISGDNAVEKYTKKFDGFDP CCCCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCC NPMQVNADQIKNAWDEIDNNLKRSLEEAHKRIQKFHEKEIPQSFTIKGEYGDIVQRRWKP CCCEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCHHHHHHHHCCC VKNAGIYIPGGRAAYPSTVLMNAIPAKVAGVAEIIMVSPGNKEGEINKTVLAAAHLSGIN CCCCCEECCCCCCCCCHHHHHHHHHHHHHCCEEEEEECCCCCCCCCHHHHHHHHHHHHHH KVFRIGGAQAIGALAFGTNQINKVDVISGPGNIYVTTAKKLIYGSTGIDSLAGPSEILII HHHHCCCHHHHHHHEECCCCCCEEEEEECCCCEEEEEEEEEEECCCCCCCCCCCCEEEEE ADETAQSTHIASDLLAQAEHDPLASSILLTTSKNQAKEVLEELYKKIEDHPRKEICMQSI ECCCCCHHHHHHHHHHHCCCCCCCCEEEEECCCHHHHHHHHHHHHHHHCCCHHHHHHHHH NNWGSIVICENSEQCVELSNNFAPEHLEILTVDPKKILAGIENAGAIFLGKWTPEAVGDY CCCCCEEEECCCHHHHHHHCCCCCCCEEEEEECHHHHHHCCCCCCEEEEECCCHHHHHHH LAGPNHTLPTSGNSRFSGSLGVETFMKNSSIIEFNEESLKVNSLDIINLAKSEGLHSHAN HCCCCCCCCCCCCCCCCCCCCHHHHHCCCCEEEECCCCEEECCEEEEEEHHHCCCCCCCC SVQIRFED EEEEEECC
PDB accession: NA
Resolution: NA
Structure class: Alpha Beta
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 9.0
TargetDB status: NA
Availability: NA
References: NA