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The map label for this gene is atpB

Identifier: 126696984

GI number: 126696984

Start: 1376551

End: 1377276

Strand: Reverse

Name: atpB

Synonym: P9301_16461

Alternate gene names: 126696984

Gene position: 1377276-1376551 (Counterclockwise)

Preceding gene: 126696985

Following gene: 126696983

Centisome position: 83.88

GC content: 34.3

Gene sequence:

>726_bases
ATGTTTTTTAATTCCTTGCTAACAAATTTTGCAGCATTAGAAGTTGGTCAACATCTTTATTGGCAAATTGGAAATATCAG
ACTACATGGGCAGGTATTTTTAACATCTTGGATTTTACTAGGAGCGTTATTAGTTTTTATTTCTTTAGGAACTAAAAAGA
TGGAAAATGATCCTAAAGGCCTTCAAAACTTGCTTGAGTTTCTTTGGGATTACATAAGAGATCTTGCTAGGACGCAAATA
GGTGAAAAAGTTTACAGAGATTGGATGCCATTTATAGGTACTTTATTTTTATTCGTCTTTGTTAGTAATTGGGGAGGAGC
TTTAATTCCTTGGAGATTGATTAAATTACCTAGTGGAGAATTAGGAGCACCTACTGCTGATATTAATACAACTATAGCCT
TGGCTTTATTGGTTTCACTTTCTTATTTCTATGCAGGTTTAAGTAATAAGGGTTGGAGATACTTCGAATACTATGTTCAC
CCAACTCCGATTATGCTTCCTTTTAAAATTCTAGAGGATTTTACTAAACCTTTATCACTCTCTTTCAGGCTATTTGGAAA
TATTTTGGCTGATGAACTTGTTGTTGGTGTTTTAGTCTTTTTAGTTCCGCTAATTCTTCCAATACCTGTTATGTTCCTAG
GATTATTTACTAGTGCAATTCAGGCATTGATTTTCGCAACTTTAGCGGCCTACTACATCGGAGAAGCTGTTGAAGAACAT
CATTAG

Upstream 100 bases:

>100_bases
TCTTTGGATATTTTTCCTGCAATGATAGGTTTTTTCATTTACAAGCCTTCACTCATTCTTTATTTTTCACGTTCTTAAGT
AAATTTTTTATTCAAAACAA

Downstream 100 bases:

>100_bases
CTGTTTCCAGATACATTCAGACGCTTTTACAAAGGGTCTGTAATCTGGCAAAATATCTAATCGCGTAGGTCTGAAAATAT
CAGACCCATTCTTAAAACAA

Product: F0F1 ATP synthase subunit A

Products: ADP; phosphate; H+

Alternate protein names: ATP synthase F0 sector subunit a; F-ATPase subunit 6

Number of amino acids: Translated: 241; Mature: 241

Protein sequence:

>241_residues
MFFNSLLTNFAALEVGQHLYWQIGNIRLHGQVFLTSWILLGALLVFISLGTKKMENDPKGLQNLLEFLWDYIRDLARTQI
GEKVYRDWMPFIGTLFLFVFVSNWGGALIPWRLIKLPSGELGAPTADINTTIALALLVSLSYFYAGLSNKGWRYFEYYVH
PTPIMLPFKILEDFTKPLSLSFRLFGNILADELVVGVLVFLVPLILPIPVMFLGLFTSAIQALIFATLAAYYIGEAVEEH
H

Sequences:

>Translated_241_residues
MFFNSLLTNFAALEVGQHLYWQIGNIRLHGQVFLTSWILLGALLVFISLGTKKMENDPKGLQNLLEFLWDYIRDLARTQI
GEKVYRDWMPFIGTLFLFVFVSNWGGALIPWRLIKLPSGELGAPTADINTTIALALLVSLSYFYAGLSNKGWRYFEYYVH
PTPIMLPFKILEDFTKPLSLSFRLFGNILADELVVGVLVFLVPLILPIPVMFLGLFTSAIQALIFATLAAYYIGEAVEEH
H
>Mature_241_residues
MFFNSLLTNFAALEVGQHLYWQIGNIRLHGQVFLTSWILLGALLVFISLGTKKMENDPKGLQNLLEFLWDYIRDLARTQI
GEKVYRDWMPFIGTLFLFVFVSNWGGALIPWRLIKLPSGELGAPTADINTTIALALLVSLSYFYAGLSNKGWRYFEYYVH
PTPIMLPFKILEDFTKPLSLSFRLFGNILADELVVGVLVFLVPLILPIPVMFLGLFTSAIQALIFATLAAYYIGEAVEEH
H

Specific function: Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane

COG id: COG0356

COG function: function code C; F0F1-type ATP synthase, subunit a

Gene ontology:

Cell location: Cellular thylakoid membrane; Multi-pass membrane protein

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ATPase A chain family

Homologues:

Organism=Saccharomyces cerevisiae, GI6226527, Length=197, Percent_Identity=28.4263959390863, Blast_Score=68, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ATP6_PROM0 (A3PEU4)

Other databases:

- EMBL:   CP000576
- RefSeq:   YP_001091870.1
- ProteinModelPortal:   A3PEU4
- STRING:   A3PEU4
- GeneID:   4911143
- GenomeReviews:   CP000576_GR
- KEGG:   pmg:P9301_16461
- eggNOG:   COG0356
- HOGENOM:   HBG734175
- OMA:   LHGQVFL
- ProtClustDB:   PRK05815
- BioCyc:   PMAR167546:P9301ORF_1678-MONOMER
- HAMAP:   MF_01393
- InterPro:   IPR000568
- InterPro:   IPR023011
- Gene3D:   G3DSA:1.20.120.220
- PANTHER:   PTHR11410
- PRINTS:   PR00123
- TIGRFAMs:   TIGR01131

Pfam domain/function: PF00119 ATP-synt_A; SSF81336 ATPase_F0_A

EC number: 3.6.3.14

Molecular weight: Translated: 27341; Mature: 27341

Theoretical pI: Translated: 6.35; Mature: 6.35

Prosite motif: PS00449 ATPASE_A

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x1f20bb00)-; HASH(0x1ef4aef4)-; HASH(0x1f32a694)-; HASH(0x1f3113b0)-; HASH(0x1e863fdc)-;

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFFNSLLTNFAALEVGQHLYWQIGNIRLHGQVFLTSWILLGALLVFISLGTKKMENDPKG
CCHHHHHHHHHHHHHHHHHHHEECCEEEEHHHHHHHHHHHHHHHHHHHHCCHHCCCCHHH
LQNLLEFLWDYIRDLARTQIGEKVYRDWMPFIGTLFLFVFVSNWGGALIPWRLIKLPSGE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHEEECCCCC
LGAPTADINTTIALALLVSLSYFYAGLSNKGWRYFEYYVHPTPIMLPFKILEDFTKPLSL
CCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEECCCCHHHHHHHHHHHHHHHHH
SFRLFGNILADELVVGVLVFLVPLILPIPVMFLGLFTSAIQALIFATLAAYYIGEAVEEH
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
H
H
>Mature Secondary Structure
MFFNSLLTNFAALEVGQHLYWQIGNIRLHGQVFLTSWILLGALLVFISLGTKKMENDPKG
CCHHHHHHHHHHHHHHHHHHHEECCEEEEHHHHHHHHHHHHHHHHHHHHCCHHCCCCHHH
LQNLLEFLWDYIRDLARTQIGEKVYRDWMPFIGTLFLFVFVSNWGGALIPWRLIKLPSGE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHEEECCCCC
LGAPTADINTTIALALLVSLSYFYAGLSNKGWRYFEYYVHPTPIMLPFKILEDFTKPLSL
CCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEECCCCHHHHHHHHHHHHHHHHH
SFRLFGNILADELVVGVLVFLVPLILPIPVMFLGLFTSAIQALIFATLAAYYIGEAVEEH
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
H
H

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: Borate; diphosphate; HCO3- [C]

Metal ions: Co2+; Fe2+; Mn2+; Zn2+ [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; H2O; H+

Specific reaction: ATP + H2O + H+(in) = ADP + phosphate + H+(out)

General reaction: Phosphorous acid anhydride hydrolysis [C]

Inhibitor: Ca2+; CN-; Efrapeptin; Ethidiumbromide; Guanidines analogs; Oligomycin; Quercetin; Trialkyl tin derivatives; Venturicidin [C]

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA