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The map label for this gene is dnaK [H]

Identifier: 126696960

GI number: 126696960

Start: 1355409

End: 1356977

Strand: Direct

Name: dnaK [H]

Synonym: P9301_16221

Alternate gene names: 126696960

Gene position: 1355409-1356977 (Clockwise)

Preceding gene: 126696956

Following gene: 126696962

Centisome position: 82.55

GC content: 29.13

Gene sequence:

>1569_bases
ATGGAAGAAAGTTTATCTGGAACACTTGCTATCGATTTAGGGAACACTAATACTGTTGTTGCTTTTCAAGATCAAAAAGA
TATAAATTCTGTTTTAGTTGAAATACCAAATATTACATCATCTCCAGGAGTTGTTCCTTCAGCAGTTTGGTTTGAGGAAC
CTTCAAAGATTACAAAAATTGGTATTAGTGCTCTAAAAATGAGGGATAACTCAAATTCTGATTTATTTTTTCATTCGAAC
TTTAAAAGATTAATTGGAAATTCTATTGAAAAAATTAACCAAAAAAATATTTTAAATCCTAATGAATGTGGCGAAAAATT
TTTTCAAATTTTATGGGCAAACATTCCGCAAAAGTATGAGATTAAAAGACTTGTTTTAACTGCTCCCATAGATACATATA
GGGGATACAGAGAATGGTTAGTTAACCTTTGCGAGGAAATATCTGTAGATGAAATAGCCCTTGTTGATGAGCCTACTGCG
GCAAGTTTAGGAATAAATGTACCATTTGGCTCAAAAATAATGACATTAGATATTGGAGGAAGTACAGTCGATATGAATAT
AGTCAAAATAGAGGGAGGAGAGGGAAAATCTGGTCCAATCGCTGAACTATTAAAATTTAAAGGTAATGATGTAAGCTCAA
TTTCAAAACAAAAAATAAGGTGTGCTGAAATAATTGGGAAAGCAGGTTCAAAAATTGGTGGGAAAGATATTGATCAATGG
ATCGTTGATTATTTTATTCCAGGTCATAACTATATTAATAATCTTTCTAAAGCAGAAAAAATAAAATGTAAACTCAGCTC
ATCTGTAATCAAATATGAAACTAAATATCCAATAAAATTATTTACTGAAAAAAATAACGAAAGTGAATTTTATCTTAGTA
AAGAAATATTTGAGAAAATACTCATTGAAAATAATTTTCTTAATCACCTTAACTCTTTACTAAAAGATTTATTAAATCAA
GCAAGAGGTAAATTTTGCACAGTTGAAGACTTAAATGCAATAGTTTTGGTTGGTGGAGGAACTCAAATACCATTGATTAA
AGAATGGATAACAAAAAAAATTCCAAAAATTCAAATAAAATCGCCACCCCCTATTGAATCAATAGCTTTGGGAGCTTTAG
CGATGACCCCGGGAGTAAAAATTAAAGATATTTTAAACAAAGGGTTATCTATAAGATTATTTAATAAAAGAGAGCAAAAA
CACTTTTGGCATCCTATTTTTTGCAAAGGTCAAACATGGCCAACAGAAAAACCCTTTAAACTGATCCTTCAAGCCAGTAA
AAACAATCAGAAAATATTCGAAATAGTAATTGGAGAGACACAAAAAGAAAGAGCATATGATGTTATTTTCGAAAATGGAT
TACCAAAGTTATCAGAGATTCAAAATGAAGAAGAAATTATAAAATGGGGCAAAAAACCACTCAAAATAGTATTAAAAAAT
AAATCTAATATTGGAGAAGATACTTTAAAACTTTTTTTTAAAATTACGAAAAATGCCGATTTATTGGTTAAGTGTTTTGA
TGTTAAAGATGAATTTTTTGGAGAATATAATTTAGGAAATATCTATTGA

Upstream 100 bases:

>100_bases
CATTAAAAAAATTTTTTACTATAAGATGTATTTTACAATTTATTCGACCATTTCAAAACATAAATTACAAAAAGAACTTA
ATTGATTTAAATAATTTCAT

Downstream 100 bases:

>100_bases
AAGATAGCTATTCAAGAAAAACTCCTTCCTCATTATCAACATTATTTAAACGTAAACTAATACTTTCTATTTTACTAGTT
GGTACTTTTTTGCCACAAAA

Product: HSP70 family molecular chaperone

Products: NA

Alternate protein names: HSP70; Heat shock 70 kDa protein; Heat shock protein 70 [H]

Number of amino acids: Translated: 522; Mature: 522

Protein sequence:

>522_residues
MEESLSGTLAIDLGNTNTVVAFQDQKDINSVLVEIPNITSSPGVVPSAVWFEEPSKITKIGISALKMRDNSNSDLFFHSN
FKRLIGNSIEKINQKNILNPNECGEKFFQILWANIPQKYEIKRLVLTAPIDTYRGYREWLVNLCEEISVDEIALVDEPTA
ASLGINVPFGSKIMTLDIGGSTVDMNIVKIEGGEGKSGPIAELLKFKGNDVSSISKQKIRCAEIIGKAGSKIGGKDIDQW
IVDYFIPGHNYINNLSKAEKIKCKLSSSVIKYETKYPIKLFTEKNNESEFYLSKEIFEKILIENNFLNHLNSLLKDLLNQ
ARGKFCTVEDLNAIVLVGGGTQIPLIKEWITKKIPKIQIKSPPPIESIALGALAMTPGVKIKDILNKGLSIRLFNKREQK
HFWHPIFCKGQTWPTEKPFKLILQASKNNQKIFEIVIGETQKERAYDVIFENGLPKLSEIQNEEEIIKWGKKPLKIVLKN
KSNIGEDTLKLFFKITKNADLLVKCFDVKDEFFGEYNLGNIY

Sequences:

>Translated_522_residues
MEESLSGTLAIDLGNTNTVVAFQDQKDINSVLVEIPNITSSPGVVPSAVWFEEPSKITKIGISALKMRDNSNSDLFFHSN
FKRLIGNSIEKINQKNILNPNECGEKFFQILWANIPQKYEIKRLVLTAPIDTYRGYREWLVNLCEEISVDEIALVDEPTA
ASLGINVPFGSKIMTLDIGGSTVDMNIVKIEGGEGKSGPIAELLKFKGNDVSSISKQKIRCAEIIGKAGSKIGGKDIDQW
IVDYFIPGHNYINNLSKAEKIKCKLSSSVIKYETKYPIKLFTEKNNESEFYLSKEIFEKILIENNFLNHLNSLLKDLLNQ
ARGKFCTVEDLNAIVLVGGGTQIPLIKEWITKKIPKIQIKSPPPIESIALGALAMTPGVKIKDILNKGLSIRLFNKREQK
HFWHPIFCKGQTWPTEKPFKLILQASKNNQKIFEIVIGETQKERAYDVIFENGLPKLSEIQNEEEIIKWGKKPLKIVLKN
KSNIGEDTLKLFFKITKNADLLVKCFDVKDEFFGEYNLGNIY
>Mature_522_residues
MEESLSGTLAIDLGNTNTVVAFQDQKDINSVLVEIPNITSSPGVVPSAVWFEEPSKITKIGISALKMRDNSNSDLFFHSN
FKRLIGNSIEKINQKNILNPNECGEKFFQILWANIPQKYEIKRLVLTAPIDTYRGYREWLVNLCEEISVDEIALVDEPTA
ASLGINVPFGSKIMTLDIGGSTVDMNIVKIEGGEGKSGPIAELLKFKGNDVSSISKQKIRCAEIIGKAGSKIGGKDIDQW
IVDYFIPGHNYINNLSKAEKIKCKLSSSVIKYETKYPIKLFTEKNNESEFYLSKEIFEKILIENNFLNHLNSLLKDLLNQ
ARGKFCTVEDLNAIVLVGGGTQIPLIKEWITKKIPKIQIKSPPPIESIALGALAMTPGVKIKDILNKGLSIRLFNKREQK
HFWHPIFCKGQTWPTEKPFKLILQASKNNQKIFEIVIGETQKERAYDVIFENGLPKLSEIQNEEEIIKWGKKPLKIVLKN
KSNIGEDTLKLFFKITKNADLLVKCFDVKDEFFGEYNLGNIY

Specific function: Acts as a chaperone [H]

COG id: COG0443

COG function: function code O; Molecular chaperone

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the heat shock protein 70 family [H]

Homologues:

Organism=Caenorhabditis elegans, GI17568549, Length=277, Percent_Identity=24.9097472924188, Blast_Score=67, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI17534771, Length=428, Percent_Identity=23.5981308411215, Blast_Score=66, Evalue=5e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012725
- InterPro:   IPR018181
- InterPro:   IPR001023
- InterPro:   IPR013126 [H]

Pfam domain/function: PF00012 HSP70 [H]

EC number: NA

Molecular weight: Translated: 58846; Mature: 58846

Theoretical pI: Translated: 8.74; Mature: 8.74

Prosite motif: PS01036 HSP70_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEESLSGTLAIDLGNTNTVVAFQDQKDINSVLVEIPNITSSPGVVPSAVWFEEPSKITKI
CCCCCCCEEEEEECCCEEEEEECCCCCHHHHHEECCCCCCCCCCCCCHHHHCCCCHHHHH
GISALKMRDNSNSDLFFHSNFKRLIGNSIEKINQKNILNPNECGEKFFQILWANIPQKYE
CHHHEEECCCCCCCEEEECCHHHHHCHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCCEE
IKRLVLTAPIDTYRGYREWLVNLCEEISVDEIALVDEPTAASLGINVPFGSKIMTLDIGG
EEEEEEECCHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCCEEEEECCCCCEEEEEEECC
STVDMNIVKIEGGEGKSGPIAELLKFKGNDVSSISKQKIRCAEIIGKAGSKIGGKDIDQW
CEEEEEEEEEECCCCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCHHHH
IVDYFIPGHNYINNLSKAEKIKCKLSSSVIKYETKYPIKLFTEKNNESEFYLSKEIFEKI
HHHHCCCCCHHHHHHHHHHHHHHEECCCEEEEECCCCEEEEEECCCCCCEEECHHHHHHH
LIENNFLNHLNSLLKDLLNQARGKFCTVEDLNAIVLVGGGTQIPLIKEWITKKIPKIQIK
HHCCHHHHHHHHHHHHHHHHHCCCEEEEECCCEEEEECCCCCCCHHHHHHHCCCCEEEEC
SPPPIESIALGALAMTPGVKIKDILNKGLSIRLFNKREQKHFWHPIFCKGQTWPTEKPFK
CCCCHHHHHHHHHHCCCCCCHHHHHCCCCEEEEECCCCCCCCCCCEEECCCCCCCCCCEE
LILQASKNNQKIFEIVIGETQKERAYDVIFENGLPKLSEIQNEEEIIKWGKKPLKIVLKN
EEEEECCCCCEEEEEEECCCCCHHHHHHHCCCCCCHHHHHCCHHHHHHCCCCCEEEEEEC
KSNIGEDTLKLFFKITKNADLLVKCFDVKDEFFGEYNLGNIY
CCCCCHHHHHHHHHCCCCCCEEEEEECCCHHHCCCCCCCCCC
>Mature Secondary Structure
MEESLSGTLAIDLGNTNTVVAFQDQKDINSVLVEIPNITSSPGVVPSAVWFEEPSKITKI
CCCCCCCEEEEEECCCEEEEEECCCCCHHHHHEECCCCCCCCCCCCCHHHHCCCCHHHHH
GISALKMRDNSNSDLFFHSNFKRLIGNSIEKINQKNILNPNECGEKFFQILWANIPQKYE
CHHHEEECCCCCCCEEEECCHHHHHCHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCCEE
IKRLVLTAPIDTYRGYREWLVNLCEEISVDEIALVDEPTAASLGINVPFGSKIMTLDIGG
EEEEEEECCHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCCEEEEECCCCCEEEEEEECC
STVDMNIVKIEGGEGKSGPIAELLKFKGNDVSSISKQKIRCAEIIGKAGSKIGGKDIDQW
CEEEEEEEEEECCCCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCHHHH
IVDYFIPGHNYINNLSKAEKIKCKLSSSVIKYETKYPIKLFTEKNNESEFYLSKEIFEKI
HHHHCCCCCHHHHHHHHHHHHHHEECCCEEEEECCCCEEEEEECCCCCCEEECHHHHHHH
LIENNFLNHLNSLLKDLLNQARGKFCTVEDLNAIVLVGGGTQIPLIKEWITKKIPKIQIK
HHCCHHHHHHHHHHHHHHHHHCCCEEEEECCCEEEEECCCCCCCHHHHHHHCCCCEEEEC
SPPPIESIALGALAMTPGVKIKDILNKGLSIRLFNKREQKHFWHPIFCKGQTWPTEKPFK
CCCCHHHHHHHHHHCCCCCCHHHHHCCCCEEEEECCCCCCCCCCCEEECCCCCCCCCCEE
LILQASKNNQKIFEIVIGETQKERAYDVIFENGLPKLSEIQNEEEIIKWGKKPLKIVLKN
EEEEECCCCCEEEEEEECCCCCHHHHHHHCCCCCCHHHHHCCHHHHHHCCCCCEEEEEEC
KSNIGEDTLKLFFKITKNADLLVKCFDVKDEFFGEYNLGNIY
CCCCCHHHHHHHHHCCCCCCEEEEEECCCHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA