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The map label for this gene is des [H]

Identifier: 126696910

GI number: 126696910

Start: 1326076

End: 1327182

Strand: Direct

Name: des [H]

Synonym: P9301_15721

Alternate gene names: 126696910

Gene position: 1326076-1327182 (Clockwise)

Preceding gene: 126696909

Following gene: 126696912

Centisome position: 80.77

GC content: 28.64

Gene sequence:

>1107_bases
ATGCTTAAAGTCAATAGAGGTGATTTTTTAATAAAGCCATTTTTAAAAAGAAATAATATTAGAGCTTCTTATCAAATTAT
TTCTACCATCTTCCCAATAATTTCTATTTGGTTAATCGTACACCAAATAATAAATCATCCTTTTTCATTATTGATTAAAG
GATTTCTATTGGTACCTTTTGTAGTTCTTCTAACACTATTCTCATCTAGAACATTCTCATTAATGCATGATTGCGGTCAT
AATTCTCTTTTTACAAAACGTAAATTAAACCGCTTCTTTGGATTTTTACTTGGCTTGGTTAATGGTATCCCTCAGAAGTC
GTGGTCAATTGATCATGCATTTCATCATAGAAATAATGGAAATTGGGAAATTTATAAGGGTCCGATAGATGTTTTAAGTC
TTGAAGATTATGAATCCCTTTCAAAAAGAGAGCAAATAATTTATAAAGTAAGTCGAAATTGGGTGATGCTTTTCCCTGGC
GGTTTTTTTTACTTAGTTTTAAAACCTAGATTAGGACTTGTTTTTATTATTTTTAATTTTAGTAAAGATATATTGGAAGA
GACTTATATCAAAATAAAAAACAGAGAAATTTCTCAACTTCTAGCAATTAATTCGAGAGTAAAACCACCTTTTTCTGATT
ATGGAGATAACTTCAGTGAGCTTTGTGAATTAATAATCAATAATATAGTAGTAATAATAGGATGGATCTTTATGAGTAAA
TGGTTGGGGTTAGTTTTTTTCTTATCATTTTATTCCATTGTATTAACCTTATCAGCAGCAATTTTAATATGTGTTTTTTT
CGTACAACATAATTATGAGAATGCATATGCTAAAAATACAAAAAACTGGGATCTCATCGATGGAGCGATTTTAGGTAGTA
GCAATTTAGATATCCCTAATTGGCTAAATTGGTTTTTAGCAGACATATCCTTCCACAGCATTCATCATCTGTCTGAAAGA
ATACCTAATTACAACTTAAGATCTTGTCATAAAGCAAACATTCATCTGCTCCAACAATCAAAGTTCTTAAAATTAAGCGA
TTTTTCAAACTGCTTCAAATATATTATTTGGGATAATAAAAATGAAAAATTAATTCCAATAAGTTAA

Upstream 100 bases:

>100_bases
CTAAAGAATTTATTCTTTAGTATGATTGTAAAATATTTTATTATTTATTAAATTATCAATACTTTTTAAAAATTGTTAGT
ATCAAAAAAATAAGAGAAAT

Downstream 100 bases:

>100_bases
TACCTAATTTAACCTTCTTCTCAATTTTCTTTTTATAGGAATACTGCTGTATGCATTAGTACCAATAGATGGAGGCAAGT
CATTCTTTAAAGGATGAATA

Product: Fatty acid desaturase, type 2

Products: NA

Alternate protein names: Delta(5) acyl-lipid desaturase; Delta(5) desaturase [H]

Number of amino acids: Translated: 368; Mature: 368

Protein sequence:

>368_residues
MLKVNRGDFLIKPFLKRNNIRASYQIISTIFPIISIWLIVHQIINHPFSLLIKGFLLVPFVVLLTLFSSRTFSLMHDCGH
NSLFTKRKLNRFFGFLLGLVNGIPQKSWSIDHAFHHRNNGNWEIYKGPIDVLSLEDYESLSKREQIIYKVSRNWVMLFPG
GFFYLVLKPRLGLVFIIFNFSKDILEETYIKIKNREISQLLAINSRVKPPFSDYGDNFSELCELIINNIVVIIGWIFMSK
WLGLVFFLSFYSIVLTLSAAILICVFFVQHNYENAYAKNTKNWDLIDGAILGSSNLDIPNWLNWFLADISFHSIHHLSER
IPNYNLRSCHKANIHLLQQSKFLKLSDFSNCFKYIIWDNKNEKLIPIS

Sequences:

>Translated_368_residues
MLKVNRGDFLIKPFLKRNNIRASYQIISTIFPIISIWLIVHQIINHPFSLLIKGFLLVPFVVLLTLFSSRTFSLMHDCGH
NSLFTKRKLNRFFGFLLGLVNGIPQKSWSIDHAFHHRNNGNWEIYKGPIDVLSLEDYESLSKREQIIYKVSRNWVMLFPG
GFFYLVLKPRLGLVFIIFNFSKDILEETYIKIKNREISQLLAINSRVKPPFSDYGDNFSELCELIINNIVVIIGWIFMSK
WLGLVFFLSFYSIVLTLSAAILICVFFVQHNYENAYAKNTKNWDLIDGAILGSSNLDIPNWLNWFLADISFHSIHHLSER
IPNYNLRSCHKANIHLLQQSKFLKLSDFSNCFKYIIWDNKNEKLIPIS
>Mature_368_residues
MLKVNRGDFLIKPFLKRNNIRASYQIISTIFPIISIWLIVHQIINHPFSLLIKGFLLVPFVVLLTLFSSRTFSLMHDCGH
NSLFTKRKLNRFFGFLLGLVNGIPQKSWSIDHAFHHRNNGNWEIYKGPIDVLSLEDYESLSKREQIIYKVSRNWVMLFPG
GFFYLVLKPRLGLVFIIFNFSKDILEETYIKIKNREISQLLAINSRVKPPFSDYGDNFSELCELIINNIVVIIGWIFMSK
WLGLVFFLSFYSIVLTLSAAILICVFFVQHNYENAYAKNTKNWDLIDGAILGSSNLDIPNWLNWFLADISFHSIHHLSER
IPNYNLRSCHKANIHLLQQSKFLKLSDFSNCFKYIIWDNKNEKLIPIS

Specific function: Catalyzes the introduction of a cis-double bond at the delta(5) position of existing saturated fatty acids attached to membrane phospholipids. It is not strictly specific for palmitic acid (C16) but can also accept C14 as well as C18 species to yield unsa

COG id: COG3239

COG function: function code I; Fatty acid desaturase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the fatty acid desaturase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005804 [H]

Pfam domain/function: PF00487 FA_desaturase [H]

EC number: 1.14.99.-

Molecular weight: Translated: 43019; Mature: 43019

Theoretical pI: Translated: 9.81; Mature: 9.81

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLKVNRGDFLIKPFLKRNNIRASYQIISTIFPIISIWLIVHQIINHPFSLLIKGFLLVPF
CCCCCCCCEEEEHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHH
VVLLTLFSSRTFSLMHDCGHNSLFTKRKLNRFFGFLLGLVNGIPQKSWSIDHAFHHRNNG
HHHHHHHCCCHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHCCCCC
NWEIYKGPIDVLSLEDYESLSKREQIIYKVSRNWVMLFPGGFFYLVLKPRLGLVFIIFNF
CEEEEECCCCEEECHHHHHHHHHHHHHHHCCCCEEEEECCCEEEEEEECCCCEEEEEECC
SKDILEETYIKIKNREISQLLAINSRVKPPFSDYGDNFSELCELIINNIVVIIGWIFMSK
CHHHHHHHHHHHCCHHHHHHHHHCCCCCCCHHHCCCCHHHHHHHHHHHHHHHHHHHHHHH
WLGLVFFLSFYSIVLTLSAAILICVFFVQHNYENAYAKNTKNWDLIDGAILGSSNLDIPN
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHCCCCCCCCCCCEEECCCCCCCHH
WLNWFLADISFHSIHHLSERIPNYNLRSCHKANIHLLQQSKFLKLSDFSNCFKYIIWDNK
HHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEECCCCCEEHHHHHHHHEEEEECCC
NEKLIPIS
CCEEECCC
>Mature Secondary Structure
MLKVNRGDFLIKPFLKRNNIRASYQIISTIFPIISIWLIVHQIINHPFSLLIKGFLLVPF
CCCCCCCCEEEEHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHH
VVLLTLFSSRTFSLMHDCGHNSLFTKRKLNRFFGFLLGLVNGIPQKSWSIDHAFHHRNNG
HHHHHHHCCCHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHCCCCC
NWEIYKGPIDVLSLEDYESLSKREQIIYKVSRNWVMLFPGGFFYLVLKPRLGLVFIIFNF
CEEEEECCCCEEECHHHHHHHHHHHHHHHCCCCEEEEECCCEEEEEEECCCCEEEEEECC
SKDILEETYIKIKNREISQLLAINSRVKPPFSDYGDNFSELCELIINNIVVIIGWIFMSK
CHHHHHHHHHHHCCHHHHHHHHHCCCCCCCHHHCCCCHHHHHHHHHHHHHHHHHHHHHHH
WLGLVFFLSFYSIVLTLSAAILICVFFVQHNYENAYAKNTKNWDLIDGAILGSSNLDIPN
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHCCCCCCCCCCCEEECCCCCCCHH
WLNWFLADISFHSIHHLSERIPNYNLRSCHKANIHLLQQSKFLKLSDFSNCFKYIIWDNK
HHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEECCCCCEEHHHHHHHHEEEEECCC
NEKLIPIS
CCEEECCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9555904; 9384377 [H]