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The map label for this gene is prmA

Identifier: 126696877

GI number: 126696877

Start: 1304823

End: 1305734

Strand: Reverse

Name: prmA

Synonym: P9301_15391

Alternate gene names: 126696877

Gene position: 1305734-1304823 (Counterclockwise)

Preceding gene: 126696878

Following gene: 126696876

Centisome position: 79.53

GC content: 28.84

Gene sequence:

>912_bases
ATGGAAACTAAAGATTGGTATAAACTAACTTTTCTGATAGAAAGTGATTCTGAAGAAATTATTATTTGGAAATTAAATGA
GCTGGGAATATTTAGTTTTTCATTTGAATATTTAATTAAAAATGAAAATAAAAAAGAAGTTAATATATGGCTTCCAATTG
ATGATTGGGATGAGAGTTCTAGAAGTAGTTTTGAAAAAATAATTATCAAACTTTTAAACATTAATCCCCCTAAGAATAAA
TTTTTTGAATGGAGTATTATCAAACAGGAGGATTGGTTAACAAGTTGGAAGAAATATTGGGCTCCTGAATTAGTAGGAAA
TCATTTTTTAATATTGCCTTGTTGGATAAATCTAAATAAAAAATTTAAAGATAAACAAATCATAAAAATTGATCCCGGAG
CAGCTTTTGGTACAGGAAGTCACCCTTCAACTTATCTTTGCTTGGAAAAAATGGAGAATATTTTATTTTCTGATAAAAAG
GTATTAGATATTGGGAGCGGTAGCGGGATTTTGAGTGTCGCCGCAAGATTACTTGGTGCTAAAGAGGTTTGTGCCGTGGA
TAATGATTATTTAGCTATAAATTCAACAAAATCTAATTTCCAACTAAATTTCGGTAATTTAAACAAATTAAATACATATT
TGGGATCTTTTAATGAGGTAATTTTAAAAAATCAACTCGAACAATTTGATTTTGTTTTATGCAATATTCTTGCTGAAGTA
ATAAAAGGAATGATTCCAAATATCTATAAGTGCTTGAGAAACAATGGGGAAGTCATTTTCAGTGGAATTCTGAATTCACA
AAAGGATGAAATTATAAAAATATTAATTCAGCATGACTTGAAATTATTGGATGTATCAACTAGAAAAGATTGGGCATGCA
TTTCTGCGCAAAAAGCCAGCAATTCAACCTAA

Upstream 100 bases:

>100_bases
TGATGATCCAATACCTAATAAGTTACTTGATACCATTATTGAAGTGGATGGGATTACCAACGCTAATCCAGTTACTCTAT
GAAGTGGCTTTAACTAGTTA

Downstream 100 bases:

>100_bases
GTATAAGTTTTTCTTATAGATACTCTTTCATACATTTTATTGTGTCATTTTTTACTTCAAAATCTCACATATCGACCTAA
TCGATGTTAAAAATGTATTT

Product: ribosomal protein L11 methyltransferase

Products: NA

Alternate protein names: L11 Mtase

Number of amino acids: Translated: 303; Mature: 303

Protein sequence:

>303_residues
METKDWYKLTFLIESDSEEIIIWKLNELGIFSFSFEYLIKNENKKEVNIWLPIDDWDESSRSSFEKIIIKLLNINPPKNK
FFEWSIIKQEDWLTSWKKYWAPELVGNHFLILPCWINLNKKFKDKQIIKIDPGAAFGTGSHPSTYLCLEKMENILFSDKK
VLDIGSGSGILSVAARLLGAKEVCAVDNDYLAINSTKSNFQLNFGNLNKLNTYLGSFNEVILKNQLEQFDFVLCNILAEV
IKGMIPNIYKCLRNNGEVIFSGILNSQKDEIIKILIQHDLKLLDVSTRKDWACISAQKASNST

Sequences:

>Translated_303_residues
METKDWYKLTFLIESDSEEIIIWKLNELGIFSFSFEYLIKNENKKEVNIWLPIDDWDESSRSSFEKIIIKLLNINPPKNK
FFEWSIIKQEDWLTSWKKYWAPELVGNHFLILPCWINLNKKFKDKQIIKIDPGAAFGTGSHPSTYLCLEKMENILFSDKK
VLDIGSGSGILSVAARLLGAKEVCAVDNDYLAINSTKSNFQLNFGNLNKLNTYLGSFNEVILKNQLEQFDFVLCNILAEV
IKGMIPNIYKCLRNNGEVIFSGILNSQKDEIIKILIQHDLKLLDVSTRKDWACISAQKASNST
>Mature_303_residues
METKDWYKLTFLIESDSEEIIIWKLNELGIFSFSFEYLIKNENKKEVNIWLPIDDWDESSRSSFEKIIIKLLNINPPKNK
FFEWSIIKQEDWLTSWKKYWAPELVGNHFLILPCWINLNKKFKDKQIIKIDPGAAFGTGSHPSTYLCLEKMENILFSDKK
VLDIGSGSGILSVAARLLGAKEVCAVDNDYLAINSTKSNFQLNFGNLNKLNTYLGSFNEVILKNQLEQFDFVLCNILAEV
IKGMIPNIYKCLRNNGEVIFSGILNSQKDEIIKILIQHDLKLLDVSTRKDWACISAQKASNST

Specific function: Methylates ribosomal protein L11

COG id: COG2264

COG function: function code J; Ribosomal protein L11 methylase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the methyltransferase superfamily. PrmA family

Homologues:

Organism=Escherichia coli, GI2367208, Length=187, Percent_Identity=33.1550802139037, Blast_Score=88, Evalue=8e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): PRMA_PROM0 (A3PEI7)

Other databases:

- EMBL:   CP000576
- RefSeq:   YP_001091763.1
- ProteinModelPortal:   A3PEI7
- SMR:   A3PEI7
- STRING:   A3PEI7
- GeneID:   4912426
- GenomeReviews:   CP000576_GR
- KEGG:   pmg:P9301_15391
- eggNOG:   COG2264
- HOGENOM:   HBG584653
- OMA:   MSFGTGY
- ProtClustDB:   PRK00517
- BioCyc:   PMAR167546:P9301ORF_1568-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00735
- InterPro:   IPR010456
- InterPro:   IPR004498
- TIGRFAMs:   TIGR00406

Pfam domain/function: PF06325 PrmA

EC number: 2.1.1.- [C]

Molecular weight: Translated: 34862; Mature: 34862

Theoretical pI: Translated: 6.30; Mature: 6.30

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
METKDWYKLTFLIESDSEEIIIWKLNELGIFSFSFEYLIKNENKKEVNIWLPIDDWDESS
CCCCCEEEEEEEEECCCCEEEEEEECCCEEEEEEEEEEEECCCCCEEEEEEECCCCCCHH
RSSFEKIIIKLLNINPPKNKFFEWSIIKQEDWLTSWKKYWAPELVGNHFLILPCWINLNK
HHHHHHHHHHHHCCCCCCCCEEEEEEECCHHHHHHHHHHCCHHHHCCCEEEEEEEEECCC
KFKDKQIIKIDPGAAFGTGSHPSTYLCLEKMENILFSDKKVLDIGSGSGILSVAARLLGA
CCCCCEEEEECCCCCCCCCCCCCHHHHHHHHHHHHCCCCEEEEECCCCCHHHHHHHHHCC
KEVCAVDNDYLAINSTKSNFQLNFGNLNKLNTYLGSFNEVILKNQLEQFDFVLCNILAEV
HHHEEECCCEEEEECCCCCEEEECCCCHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHH
IKGMIPNIYKCLRNNGEVIFSGILNSQKDEIIKILIQHDLKLLDVSTRKDWACISAQKAS
HHHHHHHHHHHHHCCCCEEEEEHHCCCHHHHHHHHHHCCCEEEEECCCCCEEEEECCCCC
NST
CCC
>Mature Secondary Structure
METKDWYKLTFLIESDSEEIIIWKLNELGIFSFSFEYLIKNENKKEVNIWLPIDDWDESS
CCCCCEEEEEEEEECCCCEEEEEEECCCEEEEEEEEEEEECCCCCEEEEEEECCCCCCHH
RSSFEKIIIKLLNINPPKNKFFEWSIIKQEDWLTSWKKYWAPELVGNHFLILPCWINLNK
HHHHHHHHHHHHCCCCCCCCEEEEEEECCHHHHHHHHHHCCHHHHCCCEEEEEEEEECCC
KFKDKQIIKIDPGAAFGTGSHPSTYLCLEKMENILFSDKKVLDIGSGSGILSVAARLLGA
CCCCCEEEEECCCCCCCCCCCCCHHHHHHHHHHHHCCCCEEEEECCCCCHHHHHHHHHCC
KEVCAVDNDYLAINSTKSNFQLNFGNLNKLNTYLGSFNEVILKNQLEQFDFVLCNILAEV
HHHEEECCCEEEEECCCCCEEEECCCCHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHH
IKGMIPNIYKCLRNNGEVIFSGILNSQKDEIIKILIQHDLKLLDVSTRKDWACISAQKAS
HHHHHHHHHHHHHCCCCEEEEEHHCCCHHHHHHHHHHCCCEEEEECCCCCEEEEECCCCC
NST
CCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: Catalyzes the methylation of ribosomal protein L11 by S-adenosyl methionine [C]

General reaction: Transferases; Transferring one-carbon groups; Methyltransferases [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA