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The map label for this gene is cobL [H]

Identifier: 126696791

GI number: 126696791

Start: 1224449

End: 1225723

Strand: Direct

Name: cobL [H]

Synonym: P9301_14531

Alternate gene names: 126696791

Gene position: 1224449-1225723 (Clockwise)

Preceding gene: 126696783

Following gene: 126696794

Centisome position: 74.58

GC content: 28.55

Gene sequence:

>1275_bases
ATGACTGAAGTTAATAGAAAAATTTATGTAATTGGTATTAATTCTTATAAATTTGAGGATCTATCTTTCAAATTACAAAA
TTTATTTTTAGAAACAGAAAATATTGCAGTTCCAAATTCATATTTTGAAGAAATTAAATCATGGAGCGAAAATGGTTTAT
TAAATAAGAAATCATTTTTTTCAAGCAAAAGCAATAACGAACTTGTTAACTGGCTTAGGTCTCAAAAAAATGATGTAATT
TTAATTTCGAGGGGAGATCCTCTTTGGTTTGGAATTGGAAGAATACTATTAGAAAATTTTTCAAAAGATGAATTAAGTTT
TTACCCTTCAAATACTTGTATTCAATTGGCATTTAGTAAGTTAAAGATTCCATGGCAAGATACTGTTAATGTAAGTATTC
ACGGCAGAGATTCGACTAAATTAATTGAGGCTCTTAAAGTAAGACCTTCAAGTCTGGCTATCATTACAGAAGCAAATAAC
AAAAGCTTAGAATTAATCAAAAAAAACCTATCACAATTAAATCTGATTGATTATTATGATTTTTGGCTTTGTGAAGAGAT
AGGCTTCGATAATGAAAATATAAGAAAATTAAATCTTAAAGAGTCATTGCCTTCTGACATATCAAGTTTGAATATTGTTG
TTCTTACAAAAACAAAAAAAAATTACTCAAATAGTAATCTTCCCCTTTTTGGAATCAGTGACCACATATTTAAGACTTTT
GATGATAGACCAAACTTATTAACTAAAAGGGAGATTCGTGTTCAAATCTTAGCTGATCTAGAGCTCCCAAAAAATGGCGT
AATATGGGATATAGGAGCAGGTTGTGGGTCAATTGGGTTAGAGGCATTAAAATTAAGGCCCAACTTAGATTTGTTTTGTA
TCGATAAAAGGTTTGGCTCAAAAGCATTAATACTTGAAAACTCAAAAAGGCTTGGCGTTAAACCAAAATTTATTTTTGAG
GAAGACATAAATAATATCTTTAAAAAGAGAATTTTAAGTTCTTTTGAAAAACCTAATAGATTAATAATTGGAGGATGCGA
TAAAAAAACTAAACTCCAGATTATTAGTAAACTAGCTCAAGGGATGGATAATGGAGACATTGTCGTTATCCCAATAATTG
ATATTCAAACTATTAAAGAATTGAAAGAGGAATTAGAGGACAAAAATTTCAAAACAAATTTAAATTTAATTCAGACCTAT
AAAAGCTTAAGTATTGCAGAGGGAATGAGACTAGAACCAAATAATCCTGTTTTTCTATTAAAAGGGAAAAAATAA

Upstream 100 bases:

>100_bases
TTTCTCCTTTCAGACAATTAATTTACTATTATAGCTCGAATAATAATAGGATAATTTAATAAAACATTCAAACAATTAAG
TTCCATTTCATTAAATATTG

Downstream 100 bases:

>100_bases
ATTTTAATAATTGTTATTTGTCAGGTTTAGCAACATGGGGCAACCCCCAACCTAATTTATTTCTTAAAACTTGGAAAAAT
TCGTAATCTTCAAGTCTAAT

Product: putative precorrin-6y methylase

Products: NA

Alternate protein names: Precorrin-6 methyltransferase; Precorrin-6Y methylase [H]

Number of amino acids: Translated: 424; Mature: 423

Protein sequence:

>424_residues
MTEVNRKIYVIGINSYKFEDLSFKLQNLFLETENIAVPNSYFEEIKSWSENGLLNKKSFFSSKSNNELVNWLRSQKNDVI
LISRGDPLWFGIGRILLENFSKDELSFYPSNTCIQLAFSKLKIPWQDTVNVSIHGRDSTKLIEALKVRPSSLAIITEANN
KSLELIKKNLSQLNLIDYYDFWLCEEIGFDNENIRKLNLKESLPSDISSLNIVVLTKTKKNYSNSNLPLFGISDHIFKTF
DDRPNLLTKREIRVQILADLELPKNGVIWDIGAGCGSIGLEALKLRPNLDLFCIDKRFGSKALILENSKRLGVKPKFIFE
EDINNIFKKRILSSFEKPNRLIIGGCDKKTKLQIISKLAQGMDNGDIVVIPIIDIQTIKELKEELEDKNFKTNLNLIQTY
KSLSIAEGMRLEPNNPVFLLKGKK

Sequences:

>Translated_424_residues
MTEVNRKIYVIGINSYKFEDLSFKLQNLFLETENIAVPNSYFEEIKSWSENGLLNKKSFFSSKSNNELVNWLRSQKNDVI
LISRGDPLWFGIGRILLENFSKDELSFYPSNTCIQLAFSKLKIPWQDTVNVSIHGRDSTKLIEALKVRPSSLAIITEANN
KSLELIKKNLSQLNLIDYYDFWLCEEIGFDNENIRKLNLKESLPSDISSLNIVVLTKTKKNYSNSNLPLFGISDHIFKTF
DDRPNLLTKREIRVQILADLELPKNGVIWDIGAGCGSIGLEALKLRPNLDLFCIDKRFGSKALILENSKRLGVKPKFIFE
EDINNIFKKRILSSFEKPNRLIIGGCDKKTKLQIISKLAQGMDNGDIVVIPIIDIQTIKELKEELEDKNFKTNLNLIQTY
KSLSIAEGMRLEPNNPVFLLKGKK
>Mature_423_residues
TEVNRKIYVIGINSYKFEDLSFKLQNLFLETENIAVPNSYFEEIKSWSENGLLNKKSFFSSKSNNELVNWLRSQKNDVIL
ISRGDPLWFGIGRILLENFSKDELSFYPSNTCIQLAFSKLKIPWQDTVNVSIHGRDSTKLIEALKVRPSSLAIITEANNK
SLELIKKNLSQLNLIDYYDFWLCEEIGFDNENIRKLNLKESLPSDISSLNIVVLTKTKKNYSNSNLPLFGISDHIFKTFD
DRPNLLTKREIRVQILADLELPKNGVIWDIGAGCGSIGLEALKLRPNLDLFCIDKRFGSKALILENSKRLGVKPKFIFEE
DINNIFKKRILSSFEKPNRLIIGGCDKKTKLQIISKLAQGMDNGDIVVIPIIDIQTIKELKEELEDKNFKTNLNLIQTYK
SLSIAEGMRLEPNNPVFLLKGKK

Specific function: Catalyzes the methylation of both C-5 and C-15 in precorrin-6Y to form precorrin-8X [H]

COG id: COG2241

COG function: function code H; Precorrin-6B methylase 1

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the precorrin methyltransferase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000878
- InterPro:   IPR014777
- InterPro:   IPR012818
- InterPro:   IPR014008
- InterPro:   IPR006365 [H]

Pfam domain/function: PF00590 TP_methylase [H]

EC number: =2.1.1.132 [H]

Molecular weight: Translated: 48530; Mature: 48399

Theoretical pI: Translated: 9.35; Mature: 9.35

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
0.7 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
0.5 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTEVNRKIYVIGINSYKFEDLSFKLQNLFLETENIAVPNSYFEEIKSWSENGLLNKKSFF
CCCCCCEEEEEEECCEEECHHHEEEEHEEEEECCEECCHHHHHHHHHHHHCCCCCCHHHC
SSKSNNELVNWLRSQKNDVILISRGDPLWFGIGRILLENFSKDELSFYPSNTCIQLAFSK
CCCCCHHHHHHHHCCCCCEEEEECCCCEEEHHHHHHHHCCCCCCEEECCCCCEEEEEHHH
LKIPWQDTVNVSIHGRDSTKLIEALKVRPSSLAIITEANNKSLELIKKNLSQLNLIDYYD
HCCCCCCEEEEEEECCCHHHHHHHHHCCCCEEEEEEECCCCHHHHHHHHHHHCEEEHHHH
FWLCEEIGFDNENIRKLNLKESLPSDISSLNIVVLTKTKKNYSNSNLPLFGISDHIFKTF
HHHHHHHCCCCCCEEEEECHHCCCCCCCCEEEEEEEECCCCCCCCCCEEEECCHHHHHHC
DDRPNLLTKREIRVQILADLELPKNGVIWDIGAGCGSIGLEALKLRPNLDLFCIDKRFGS
CCCCCCEECCEEEEEEEEECCCCCCCEEEEECCCCCCCCCEEEEECCCCCEEEEECCCCC
KALILENSKRLGVKPKFIFEEDINNIFKKRILSSFEKPNRLIIGGCDKKTKLQIISKLAQ
EEEEEECCCCCCCCCEEEEHHHHHHHHHHHHHHHHCCCCEEEEECCCCHHHHHHHHHHHC
GMDNGDIVVIPIIDIQTIKELKEELEDKNFKTNLNLIQTYKSLSIAEGMRLEPNNPVFLL
CCCCCCEEEEEECCHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCCEECCCCCEEEE
KGKK
ECCC
>Mature Secondary Structure 
TEVNRKIYVIGINSYKFEDLSFKLQNLFLETENIAVPNSYFEEIKSWSENGLLNKKSFF
CCCCCEEEEEEECCEEECHHHEEEEHEEEEECCEECCHHHHHHHHHHHHCCCCCCHHHC
SSKSNNELVNWLRSQKNDVILISRGDPLWFGIGRILLENFSKDELSFYPSNTCIQLAFSK
CCCCCHHHHHHHHCCCCCEEEEECCCCEEEHHHHHHHHCCCCCCEEECCCCCEEEEEHHH
LKIPWQDTVNVSIHGRDSTKLIEALKVRPSSLAIITEANNKSLELIKKNLSQLNLIDYYD
HCCCCCCEEEEEEECCCHHHHHHHHHCCCCEEEEEEECCCCHHHHHHHHHHHCEEEHHHH
FWLCEEIGFDNENIRKLNLKESLPSDISSLNIVVLTKTKKNYSNSNLPLFGISDHIFKTF
HHHHHHHCCCCCCEEEEECHHCCCCCCCCEEEEEEEECCCCCCCCCCEEEECCHHHHHHC
DDRPNLLTKREIRVQILADLELPKNGVIWDIGAGCGSIGLEALKLRPNLDLFCIDKRFGS
CCCCCCEECCEEEEEEEEECCCCCCCEEEEECCCCCCCCCEEEEECCCCCEEEEECCCCC
KALILENSKRLGVKPKFIFEEDINNIFKKRILSSFEKPNRLIIGGCDKKTKLQIISKLAQ
EEEEEECCCCCCCCCEEEEHHHHHHHHHHHHHHHHCCCCEEEEECCCCHHHHHHHHHHHC
GMDNGDIVVIPIIDIQTIKELKEELEDKNFKTNLNLIQTYKSLSIAEGMRLEPNNPVFLL
CCCCCCEEEEEECCHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCCEECCCCCEEEE
KGKK
ECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 2211521; 1732195 [H]