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The map label for this gene is trxB [H]

Identifier: 126696678

GI number: 126696678

Start: 1120275

End: 1121651

Strand: Direct

Name: trxB [H]

Synonym: P9301_13401

Alternate gene names: 126696678

Gene position: 1120275-1121651 (Clockwise)

Preceding gene: 126696677

Following gene: 126696683

Centisome position: 68.23

GC content: 36.75

Gene sequence:

>1377_bases
ATGGAAAATAAAGAGAAGATTCCAAACGTAGAAAATGTTGTAATTATTGGTTCAGGTCCCGCAGGATACACAGCTGCAAT
TTATGCTGCAAGAGCAAATCTTCAACCATTGCTCGTTACAGGATTTAATTCTGGTGGAATTCCTGGTGGCCAATTGATGA
CTACAACATTTGTTGAAAATTATCCAGGTTTCCCAGATGGTGTACTTGGTCCTGAATTAATGGATCTAATGAAAGCTCAA
GCCGAAAGATGGGGCACTAATTTATATGAAAGTGATGTTGTCTCAATAAATACTGATTCACATCCCTTTGAATTAAAAAC
TTTAGAAGGAACTATAAAATCTAACTCAATTATTATTGCAACTGGAGCAAGTGCAAATAGATTAGGCGTGATAAATGAAG
ATAAATTCTGGAGTAAAGGAATAAGTGCTTGTGCAATATGTGATGGAGCGACCCCACAATTTAGAGGTGAAGAATTAGCT
GTTATTGGAGGGGGCGACTCTGCATGTGAAGAAGCAGCATATCTCACAAAGTATGGAAGCAAAGTGCATTTGATTGTTAG
ATCAGAAAAATTAAGGGCTAGCGCGGCAATGGTAGATAGAGTAAAAGCTAATCCAAAGATAGCAATTCATTGGAACACAA
AAGTTGAAAAAGCGGATGGCTCTGAATGGCTTGAGAAAATAGAAACTATTCACTCTCAAGAAGGTAAAGGGGAAATCAAT
ATAAAAGGTCTTTTTTACGCGATAGGGCACACACCAAATACTAAGTTCTTAGGCAGCAAAATTGACTTAGATAATAAAGG
ATATATTGCTTGCAAATCAGGAAGACCAGAAACATCTATTGAAGGCATCTTCGCAGCAGGTGACGTTGTCGACTCTGAGT
GGAGACAAGGAGTTACCGCTGCTGGAACTGGGTGCATGGCAGCATTAGCTACCGAAAGGTGGCTAGCCGAGAAAAACTTA
GCAAAAACAATAGTCAGAGAAACACCCGAACCAGAAAAAAAACTTAATTCATCAGATTTTAATGAAGAAGAAGTTAATGA
AGATACTTTCGATTCAAATTCTGAATGGCAAAAAGGCAGTTATGCATTAAGGAAACTTTATCACGAGAGTAAAAAACCTA
TCTTAGTAATTTTTAGTTCTCCAAGTTGCGGCCCATGTCATGTTTTGAAACCTCAGTTAAAAAGGGTAATTAAAGAACTT
GATGGTGCAGTTCTTGGCGTTGAAATAGATATTGATAAAGATCAAGATATTGCAAAACAAGCTGGTATTAACGGCACACC
AACAGTTCAACTTTTTAAAGAAAAATTATTAAAAAAACAGTGGCAAGGTGTTAAACAAAGAAGTGAGTTTAAAGAAGCGA
TAAAAAATATTATCTAA

Upstream 100 bases:

>100_bases
AGACCCAAAAATCAACGATTAAATATCAAATCGATCGAGTGGAAACCGCCCTACATTATTTGGGTTTGTTTATTATTATT
AGAGTGAAATTAGCAAATAA

Downstream 100 bases:

>100_bases
AGTAACTTTTTATTTATTATTTCTCTTAGGGTTATTTTTATTAGTAGTTGGTTTAGCATTTCCTGCATTTCTTTCTCTAT
AAGTTATCCTCCCTCTAGAG

Product: putative thioredoxin reductase

Products: NA

Alternate protein names: TRXR [H]

Number of amino acids: Translated: 458; Mature: 458

Protein sequence:

>458_residues
MENKEKIPNVENVVIIGSGPAGYTAAIYAARANLQPLLVTGFNSGGIPGGQLMTTTFVENYPGFPDGVLGPELMDLMKAQ
AERWGTNLYESDVVSINTDSHPFELKTLEGTIKSNSIIIATGASANRLGVINEDKFWSKGISACAICDGATPQFRGEELA
VIGGGDSACEEAAYLTKYGSKVHLIVRSEKLRASAAMVDRVKANPKIAIHWNTKVEKADGSEWLEKIETIHSQEGKGEIN
IKGLFYAIGHTPNTKFLGSKIDLDNKGYIACKSGRPETSIEGIFAAGDVVDSEWRQGVTAAGTGCMAALATERWLAEKNL
AKTIVRETPEPEKKLNSSDFNEEEVNEDTFDSNSEWQKGSYALRKLYHESKKPILVIFSSPSCGPCHVLKPQLKRVIKEL
DGAVLGVEIDIDKDQDIAKQAGINGTPTVQLFKEKLLKKQWQGVKQRSEFKEAIKNII

Sequences:

>Translated_458_residues
MENKEKIPNVENVVIIGSGPAGYTAAIYAARANLQPLLVTGFNSGGIPGGQLMTTTFVENYPGFPDGVLGPELMDLMKAQ
AERWGTNLYESDVVSINTDSHPFELKTLEGTIKSNSIIIATGASANRLGVINEDKFWSKGISACAICDGATPQFRGEELA
VIGGGDSACEEAAYLTKYGSKVHLIVRSEKLRASAAMVDRVKANPKIAIHWNTKVEKADGSEWLEKIETIHSQEGKGEIN
IKGLFYAIGHTPNTKFLGSKIDLDNKGYIACKSGRPETSIEGIFAAGDVVDSEWRQGVTAAGTGCMAALATERWLAEKNL
AKTIVRETPEPEKKLNSSDFNEEEVNEDTFDSNSEWQKGSYALRKLYHESKKPILVIFSSPSCGPCHVLKPQLKRVIKEL
DGAVLGVEIDIDKDQDIAKQAGINGTPTVQLFKEKLLKKQWQGVKQRSEFKEAIKNII
>Mature_458_residues
MENKEKIPNVENVVIIGSGPAGYTAAIYAARANLQPLLVTGFNSGGIPGGQLMTTTFVENYPGFPDGVLGPELMDLMKAQ
AERWGTNLYESDVVSINTDSHPFELKTLEGTIKSNSIIIATGASANRLGVINEDKFWSKGISACAICDGATPQFRGEELA
VIGGGDSACEEAAYLTKYGSKVHLIVRSEKLRASAAMVDRVKANPKIAIHWNTKVEKADGSEWLEKIETIHSQEGKGEIN
IKGLFYAIGHTPNTKFLGSKIDLDNKGYIACKSGRPETSIEGIFAAGDVVDSEWRQGVTAAGTGCMAALATERWLAEKNL
AKTIVRETPEPEKKLNSSDFNEEEVNEDTFDSNSEWQKGSYALRKLYHESKKPILVIFSSPSCGPCHVLKPQLKRVIKEL
DGAVLGVEIDIDKDQDIAKQAGINGTPTVQLFKEKLLKKQWQGVKQRSEFKEAIKNII

Specific function: Unknown

COG id: COG0492

COG function: function code O; Thioredoxin reductase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family [H]

Homologues:

Organism=Escherichia coli, GI1787114, Length=313, Percent_Identity=44.0894568690096, Blast_Score=256, Evalue=2e-69,
Organism=Escherichia coli, GI87081763, Length=317, Percent_Identity=31.5457413249211, Blast_Score=124, Evalue=1e-29,
Organism=Saccharomyces cerevisiae, GI6320560, Length=310, Percent_Identity=51.2903225806452, Blast_Score=308, Evalue=1e-84,
Organism=Saccharomyces cerevisiae, GI6321898, Length=313, Percent_Identity=48.2428115015974, Blast_Score=296, Evalue=3e-81,

Paralogues:

None

Copy number: 808 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 2,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013027
- InterPro:   IPR008255
- InterPro:   IPR001327
- InterPro:   IPR000103
- InterPro:   IPR005982 [H]

Pfam domain/function: PF00070 Pyr_redox; PF07992 Pyr_redox_2 [H]

EC number: =1.8.1.9 [H]

Molecular weight: Translated: 49933; Mature: 49933

Theoretical pI: Translated: 5.99; Mature: 5.99

Prosite motif: PS00573 PYRIDINE_REDOX_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MENKEKIPNVENVVIIGSGPAGYTAAIYAARANLQPLLVTGFNSGGIPGGQLMTTTFVEN
CCCCHHCCCCCEEEEEECCCCCCEEEEEEHHCCCCEEEEEECCCCCCCCCCEEEEEHHHC
YPGFPDGVLGPELMDLMKAQAERWGTNLYESDVVSINTDSHPFELKTLEGTIKSNSIIIA
CCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCEEEECCCCCCEEEEEEECEECCCCEEEE
TGASANRLGVINEDKFWSKGISACAICDGATPQFRGEELAVIGGGDSACEEAAYLTKYGS
ECCCCCEEEECCCCHHHHHCCCEEEEECCCCCCCCCCEEEEEECCCHHHHHHHHHHHCCC
KVHLIVRSEKLRASAAMVDRVKANPKIAIHWNTKVEKADGSEWLEKIETIHSQEGKGEIN
EEEEEEECCHHHHHHHHHHHHCCCCEEEEEECCEEECCCCHHHHHHHHHHHCCCCCCEEE
IKGLFYAIGHTPNTKFLGSKIDLDNKGYIACKSGRPETSIEGIFAAGDVVDSEWRQGVTA
EEEEEEEECCCCCCCCCCCEECCCCCCEEEECCCCCCCCCCEEEEECCCCHHHHHCCCCC
AGTGCMAALATERWLAEKNLAKTIVRETPEPEKKLNSSDFNEEEVNEDTFDSNSEWQKGS
CCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHCCCCCCCHHHCCCCCCCCCCCCCHHH
YALRKLYHESKKPILVIFSSPSCGPCHVLKPQLKRVIKELDGAVLGVEIDIDKDQDIAKQ
HHHHHHHHHCCCCEEEEECCCCCCCCCCCCHHHHHHHHHHCCEEEEEEEECCCCHHHHHH
AGINGTPTVQLFKEKLLKKQWQGVKQRSEFKEAIKNII
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MENKEKIPNVENVVIIGSGPAGYTAAIYAARANLQPLLVTGFNSGGIPGGQLMTTTFVEN
CCCCHHCCCCCEEEEEECCCCCCEEEEEEHHCCCCEEEEEECCCCCCCCCCEEEEEHHHC
YPGFPDGVLGPELMDLMKAQAERWGTNLYESDVVSINTDSHPFELKTLEGTIKSNSIIIA
CCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCEEEECCCCCCEEEEEEECEECCCCEEEE
TGASANRLGVINEDKFWSKGISACAICDGATPQFRGEELAVIGGGDSACEEAAYLTKYGS
ECCCCCEEEECCCCHHHHHCCCEEEEECCCCCCCCCCEEEEEECCCHHHHHHHHHHHCCC
KVHLIVRSEKLRASAAMVDRVKANPKIAIHWNTKVEKADGSEWLEKIETIHSQEGKGEIN
EEEEEEECCHHHHHHHHHHHHCCCCEEEEEECCEEECCCCHHHHHHHHHHHCCCCCCEEE
IKGLFYAIGHTPNTKFLGSKIDLDNKGYIACKSGRPETSIEGIFAAGDVVDSEWRQGVTA
EEEEEEEECCCCCCCCCCCEECCCCCCEEEECCCCCCCCCCEEEEECCCCHHHHHCCCCC
AGTGCMAALATERWLAEKNLAKTIVRETPEPEKKLNSSDFNEEEVNEDTFDSNSEWQKGS
CCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHCCCCCCCHHHCCCCCCCCCCCCCHHH
YALRKLYHESKKPILVIFSSPSCGPCHVLKPQLKRVIKELDGAVLGVEIDIDKDQDIAKQ
HHHHHHHHHCCCCEEEEECCCCCCCCCCCCHHHHHHHHHHCCEEEEEEEECCCCHHHHHH
AGINGTPTVQLFKEKLLKKQWQGVKQRSEFKEAIKNII
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10684935 [H]