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The map label for this gene is coaD

Identifier: 126696313

GI number: 126696313

Start: 844388

End: 844861

Strand: Reverse

Name: coaD

Synonym: P9301_09751

Alternate gene names: 126696313

Gene position: 844861-844388 (Counterclockwise)

Preceding gene: 126696318

Following gene: 126696308

Centisome position: 51.46

GC content: 27.64

Gene sequence:

>474_bases
ATGAAAATTCTTTATCCAGGTACATTTGATCCTTTAACAAATGGGCATCTTGATTTAATAGAAAGGGCTGAAAAAATATT
TGGCAAACTAGTAGTTGCTGTTTTAGAAAATACCTCTAAAACACCAACATTTAATCTTGAAAGAAGAATAATACAAATAA
AAAATTCTCTTTCTCATTTACCTAATATTGAAGTTATTTCTTATTCTGGTCTAACTGTTGATTGTGCAAATGATCTAAAA
GCTAATCTTATTCTTAGAGGCTTAAGAGCAATGAGTGATTTTGAGTATGAACTACAGATTGCTCATACAAATAAATCACT
TAATAATGATATTGAAACTATATTTTTATCGACAAATACAAATTATAGTTTTCTTAGTAGTTCTTTAGTAAAAGAAGTTG
CAAAATTTGGTGGTGAAATTAATCACATGGTACCCCCCTCTGTTGAGAAGGATTTAAAAGATTATTTTAAATAA

Upstream 100 bases:

>100_bases
TTTCTTAATAAGATTTTTTTTGCTTCTAGATTTAATGTCATAATTGATTTAACTAATAATATTATTTTAACTAAATTTCT
TATTCGATCATAATAAATTC

Downstream 100 bases:

>100_bases
TATTTTTTTAACAGGATCTCAAGTAATAAAGATCACGTAATAAATTAAAAGCTTTTTCTTTATCAATTTTATTAGAATTT
TGGATAATGCTTATAATTAT

Product: phosphopantetheine adenylyltransferase

Products: NA

Alternate protein names: Dephospho-CoA pyrophosphorylase; Pantetheine-phosphate adenylyltransferase; PPAT

Number of amino acids: Translated: 157; Mature: 157

Protein sequence:

>157_residues
MKILYPGTFDPLTNGHLDLIERAEKIFGKLVVAVLENTSKTPTFNLERRIIQIKNSLSHLPNIEVISYSGLTVDCANDLK
ANLILRGLRAMSDFEYELQIAHTNKSLNNDIETIFLSTNTNYSFLSSSLVKEVAKFGGEINHMVPPSVEKDLKDYFK

Sequences:

>Translated_157_residues
MKILYPGTFDPLTNGHLDLIERAEKIFGKLVVAVLENTSKTPTFNLERRIIQIKNSLSHLPNIEVISYSGLTVDCANDLK
ANLILRGLRAMSDFEYELQIAHTNKSLNNDIETIFLSTNTNYSFLSSSLVKEVAKFGGEINHMVPPSVEKDLKDYFK
>Mature_157_residues
MKILYPGTFDPLTNGHLDLIERAEKIFGKLVVAVLENTSKTPTFNLERRIIQIKNSLSHLPNIEVISYSGLTVDCANDLK
ANLILRGLRAMSDFEYELQIAHTNKSLNNDIETIFLSTNTNYSFLSSSLVKEVAKFGGEINHMVPPSVEKDLKDYFK

Specific function: Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate

COG id: COG0669

COG function: function code H; Phosphopantetheine adenylyltransferase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial CoaD family

Homologues:

Organism=Escherichia coli, GI1790065, Length=151, Percent_Identity=43.7086092715232, Blast_Score=159, Evalue=8e-41,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): COAD_PROM0 (A3PCX3)

Other databases:

- EMBL:   CP000576
- RefSeq:   YP_001091199.1
- ProteinModelPortal:   A3PCX3
- SMR:   A3PCX3
- STRING:   A3PCX3
- GeneID:   4911667
- GenomeReviews:   CP000576_GR
- KEGG:   pmg:P9301_09751
- eggNOG:   COG0669
- HOGENOM:   HBG288308
- OMA:   VRQIAAM
- ProtClustDB:   PRK00168
- BioCyc:   PMAR167546:P9301ORF_0993-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00151
- InterPro:   IPR004821
- InterPro:   IPR004820
- InterPro:   IPR001980
- InterPro:   IPR014729
- Gene3D:   G3DSA:3.40.50.620
- PRINTS:   PR01020
- TIGRFAMs:   TIGR01510
- TIGRFAMs:   TIGR00125

Pfam domain/function: PF01467 CTP_transf_2

EC number: =2.7.7.3

Molecular weight: Translated: 17706; Mature: 17706

Theoretical pI: Translated: 6.52; Mature: 6.52

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKILYPGTFDPLTNGHLDLIERAEKIFGKLVVAVLENTSKTPTFNLERRIIQIKNSLSHL
CEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHC
PNIEVISYSGLTVDCANDLKANLILRGLRAMSDFEYELQIAHTNKSLNNDIETIFLSTNT
CCCEEEEECCEEEECCHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCCCEEEEEEECCC
NYSFLSSSLVKEVAKFGGEINHMVPPSVEKDLKDYFK
CHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHCC
>Mature Secondary Structure
MKILYPGTFDPLTNGHLDLIERAEKIFGKLVVAVLENTSKTPTFNLERRIIQIKNSLSHL
CEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHC
PNIEVISYSGLTVDCANDLKANLILRGLRAMSDFEYELQIAHTNKSLNNDIETIFLSTNT
CCCEEEEECCEEEECCHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCCCEEEEEEECCC
NYSFLSSSLVKEVAKFGGEINHMVPPSVEKDLKDYFK
CHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA