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The map label for this gene is trpD

Identifier: 126696244

GI number: 126696244

Start: 778474

End: 779508

Strand: Direct

Name: trpD

Synonym: P9301_09061

Alternate gene names: 126696244

Gene position: 778474-779508 (Clockwise)

Preceding gene: 126696243

Following gene: 126696245

Centisome position: 47.41

GC content: 34.78

Gene sequence:

>1035_bases
ATGTCTACTAATCTATCAAACGCTGAAATCCTAAATAATTTGTTGGAGGGAAGGGACCTTGATGAATTAACTTCTAGAGC
TTTAATGCAAAGATGGCTTAATGATGAAATTTCAGATGTTGAAACAGGAGCTTTTTTGAGTGCTTTAAGAGCTAAGAGCT
CTACAGGTGTCGAACTAAGTTCTATGGCGAAGGAACTTTTAAATGTTTGCGAATTGCCAGTAGCAAGGCCAAATTTGTAT
TTGGTAGATACTTGTGGAACCGGAGGAGATGGAGCTAATACATTTAATATTTCAACTGCAGTAGCATTTGTAGCCGCATC
TTGCGGGGTAAAAATTGCAAAACATGGAAATAAAAGTGCTAGTGGGAAAGTTGGCTCTGCTGATGTTTTGTTAAATCTTG
GTTTGAATTTAAATTGTTCTTTAGAAAAAGTAATCAATGCAGTAAGTGAGATTGGAATAACTTTTTTGTTCGCACCTGTT
TGGCATAAATCTTTAATAAAACTTGCTCCATTAAGAAAGACCCTTGGAATAAGGACAGTATTTAACCAACTAGGACCATT
AGTAAATCCCTTAAGGCCCAATGCGCAAGTTTTGGGTGTTGCTTCTGAGGATCTTTTACAACCTATGGGAAGCGCCCTTT
TAAATTTGGGTATGAATAGAGCAATAGTAGTTCACGGTTCTGGCGGCCTTGATGAAGCTTCGCTTCAAGGAAAAAATAAA
TTAGTGTTTATTGAAAATGGTGAATTACGTTTTTCAGAAATAAATATTTCAGATTTTAACCATGAAAATATTGCTAACGA
AAACCTTGTGGTTTCTGATCTTGACTCTAATGAGGAAATATTAAAGTCTGTTTTAAATGGATCCGGACAAAAATCTCATA
TGGATGTTGTTGCATTGAATGTTTCTTTAGTCCTGTGGGCAGCAGGAATTGAGGATAACTTAAATGAAGGGTTTAATAAA
GCTTTATTTTCGATTAATAAAGGAGATCCGTGGAAAAAGTTTTTACTTTTAAAAAATTATTTATCAGCAAATTAA

Upstream 100 bases:

>100_bases
AAAAAGCTTCAGGCCTTCTAATACAAATAAAGATTTAGTTGGCTCAGGTTTTGATACCTCAAATTGAAATTTATCTGCAT
AATTTTTCTTCCACAAATGT

Downstream 100 bases:

>100_bases
TTAATTTCACCTAGATGATTAATCCATATAAGAAAAACGCAAAATTAGTTTTAAGTAATGGAATTGTATTTCCTGGATTT
TATTTTGGTGCTTCTGGTAC

Product: anthranilate phosphoribosyltransferase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 344; Mature: 343

Protein sequence:

>344_residues
MSTNLSNAEILNNLLEGRDLDELTSRALMQRWLNDEISDVETGAFLSALRAKSSTGVELSSMAKELLNVCELPVARPNLY
LVDTCGTGGDGANTFNISTAVAFVAASCGVKIAKHGNKSASGKVGSADVLLNLGLNLNCSLEKVINAVSEIGITFLFAPV
WHKSLIKLAPLRKTLGIRTVFNQLGPLVNPLRPNAQVLGVASEDLLQPMGSALLNLGMNRAIVVHGSGGLDEASLQGKNK
LVFIENGELRFSEINISDFNHENIANENLVVSDLDSNEEILKSVLNGSGQKSHMDVVALNVSLVLWAAGIEDNLNEGFNK
ALFSINKGDPWKKFLLLKNYLSAN

Sequences:

>Translated_344_residues
MSTNLSNAEILNNLLEGRDLDELTSRALMQRWLNDEISDVETGAFLSALRAKSSTGVELSSMAKELLNVCELPVARPNLY
LVDTCGTGGDGANTFNISTAVAFVAASCGVKIAKHGNKSASGKVGSADVLLNLGLNLNCSLEKVINAVSEIGITFLFAPV
WHKSLIKLAPLRKTLGIRTVFNQLGPLVNPLRPNAQVLGVASEDLLQPMGSALLNLGMNRAIVVHGSGGLDEASLQGKNK
LVFIENGELRFSEINISDFNHENIANENLVVSDLDSNEEILKSVLNGSGQKSHMDVVALNVSLVLWAAGIEDNLNEGFNK
ALFSINKGDPWKKFLLLKNYLSAN
>Mature_343_residues
STNLSNAEILNNLLEGRDLDELTSRALMQRWLNDEISDVETGAFLSALRAKSSTGVELSSMAKELLNVCELPVARPNLYL
VDTCGTGGDGANTFNISTAVAFVAASCGVKIAKHGNKSASGKVGSADVLLNLGLNLNCSLEKVINAVSEIGITFLFAPVW
HKSLIKLAPLRKTLGIRTVFNQLGPLVNPLRPNAQVLGVASEDLLQPMGSALLNLGMNRAIVVHGSGGLDEASLQGKNKL
VFIENGELRFSEINISDFNHENIANENLVVSDLDSNEEILKSVLNGSGQKSHMDVVALNVSLVLWAAGIEDNLNEGFNKA
LFSINKGDPWKKFLLLKNYLSAN

Specific function: Tryptophan biosynthesis; first step. Tryptophan biosynthesis; second step. [C]

COG id: COG0547

COG function: function code E; Anthranilate phosphoribosyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the anthranilate phosphoribosyltransferase family

Homologues:

Organism=Escherichia coli, GI1787517, Length=303, Percent_Identity=38.2838283828383, Blast_Score=192, Evalue=2e-50,
Organism=Saccharomyces cerevisiae, GI6320561, Length=322, Percent_Identity=31.3664596273292, Blast_Score=113, Evalue=4e-26,

Paralogues:

None

Copy number: 945 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 900 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): TRPD_PROM0 (A3PCQ4)

Other databases:

- EMBL:   CP000576
- RefSeq:   YP_001091130.1
- ProteinModelPortal:   A3PCQ4
- SMR:   A3PCQ4
- STRING:   A3PCQ4
- GeneID:   4912334
- GenomeReviews:   CP000576_GR
- KEGG:   pmg:P9301_09061
- eggNOG:   COG0547
- HOGENOM:   HBG559996
- OMA:   HGNKSAS
- ProtClustDB:   PRK00188
- BioCyc:   PMAR167546:P9301ORF_0924-MONOMER
- HAMAP:   MF_00211
- InterPro:   IPR005940
- InterPro:   IPR000312
- InterPro:   IPR017459
- InterPro:   IPR020072
- Gene3D:   G3DSA:1.20.970.10
- Gene3D:   G3DSA:3.40.1030.10
- TIGRFAMs:   TIGR01245

Pfam domain/function: PF02885 Glycos_trans_3N; PF00591 Glycos_transf_3; SSF47648 Glyco_trans_3; SSF52418 Glyco_trans_3

EC number: =2.4.2.18

Molecular weight: Translated: 36881; Mature: 36749

Theoretical pI: Translated: 5.21; Mature: 5.21

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSTNLSNAEILNNLLEGRDLDELTSRALMQRWLNDEISDVETGAFLSALRAKSSTGVELS
CCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCCCHH
SMAKELLNVCELPVARPNLYLVDTCGTGGDGANTFNISTAVAFVAASCGVKIAKHGNKSA
HHHHHHHHHHCCCCCCCCEEEEECCCCCCCCCCEEEHHHHHHHHHHHCCEEEECCCCCCC
SGKVGSADVLLNLGLNLNCSLEKVINAVSEIGITFLFAPVWHKSLIKLAPLRKTLGIRTV
CCCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHEEEHHHHHHHHHHHHHHHHHHHHHHH
FNQLGPLVNPLRPNAQVLGVASEDLLQPMGSALLNLGMNRAIVVHGSGGLDEASLQGKNK
HHHHCHHCCCCCCCCEEEECCHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCHHCCCCCC
LVFIENGELRFSEINISDFNHENIANENLVVSDLDSNEEILKSVLNGSGQKSHMDVVALN
EEEEECCCEEEEEECCCCCCCCCCCCCCEEEEECCCCHHHHHHHHCCCCCCCCEEEEEEE
VSLVLWAAGIEDNLNEGFNKALFSINKGDPWKKFLLLKNYLSAN
EEEEEEECCCCCHHHHHHHHHHEECCCCCHHHHHHHHHHHHCCC
>Mature Secondary Structure 
STNLSNAEILNNLLEGRDLDELTSRALMQRWLNDEISDVETGAFLSALRAKSSTGVELS
CCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCCCHH
SMAKELLNVCELPVARPNLYLVDTCGTGGDGANTFNISTAVAFVAASCGVKIAKHGNKSA
HHHHHHHHHHCCCCCCCCEEEEECCCCCCCCCCEEEHHHHHHHHHHHCCEEEECCCCCCC
SGKVGSADVLLNLGLNLNCSLEKVINAVSEIGITFLFAPVWHKSLIKLAPLRKTLGIRTV
CCCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHEEEHHHHHHHHHHHHHHHHHHHHHHH
FNQLGPLVNPLRPNAQVLGVASEDLLQPMGSALLNLGMNRAIVVHGSGGLDEASLQGKNK
HHHHCHHCCCCCCCCEEEECCHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCHHCCCCCC
LVFIENGELRFSEINISDFNHENIANENLVVSDLDSNEEILKSVLNGSGQKSHMDVVALN
EEEEECCCEEEEEECCCCCCCCCCCCCCEEEEECCCCHHHHHHHHCCCCCCCCEEEEEEE
VSLVLWAAGIEDNLNEGFNKALFSINKGDPWKKFLLLKNYLSAN
EEEEEEECCCCCHHHHHHHHHHEECCCCCHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA