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The map label for this gene is ureC

Identifier: 126696231

GI number: 126696231

Start: 766868

End: 768577

Strand: Direct

Name: ureC

Synonym: P9301_08931

Alternate gene names: 126696231

Gene position: 766868-768577 (Clockwise)

Preceding gene: 126696230

Following gene: 126696233

Centisome position: 46.71

GC content: 37.25

Gene sequence:

>1710_bases
ATGTCCTATAAAATTGACAGAAATACTTATGCGCAAACTTTCGGACCCACTACCGGAGATAGAGTAAGGCTTGCTGACAC
TGAACTTTTTATAGAAGTAGAAAAGGATTTAACAACATACGGGGATGAAGTTAAATTCGGAGGAGGTAAAGTTATTCGAG
ATGGGATGGGACAGTCTCAAGTAAGAAGAGCTGATGGAGCTGTAGATACGGTAATAACTAATGCTTTGATAGTAGATTGG
TGGGGAATAATTAAGGCTGATGTAGGTATAAAAGATGGAATGATTTTTGAAATTGGTAAGGCTGGTAATCCTGATATCCA
GGACAATGTTGATATTGTTATTGGTGCATCTACAGAAGTAATAGCTGGAGAGGGGCATATTCTTACTGCAGGTTCAATAG
ATACCCATATTCACTTTATCTGTCCCCAACAAATTGAGACAGCACTAGCCTCAGGAATTACAACTATGTTGGGAGGAGGA
ACTGGGCCTGCAACTGGCACAAATGCCACTACTTGTACTCCAGGTTCTTTTCATATTTCAAGAATGCTCCAATCTGCAGA
AGCATTTCCCATGAATTTAGGTTTTTTTGGAAAAGGAAACTCAACAAATGAGACCAATCTTATTGATCAAGTTGAAGCTG
GTGCATGTGGATTGAAGCTTCATGAGGATTGGGGAACGACTCCATCTACAATAAATTCTTGTCTTAATGTTGCAGATAAG
TTTGACGTACAAGTTTGTATTCATACTGATACTTTGAATGAGGCAGGCTTTGTTGAAGATACTATTAACGCAATTGCAGG
AAGAACTATTCATACCTTTCATACAGAAGGAGCAGGTGGAGGTCATGCGCCAGACATTATTAAAATTTGTGGAGAAAAAA
ATGTTCTTCCAAGTAGTACTAATCCAACAAGACCCTATACCAGGAATACATTAGAAGAACATCTTGACATGTTAATGGTC
TGTCATCATTTAGATTCTAAAATCCCGGAAGACATTGCTTTTGCTGAATCAAGGATCAGAAGAGAGACTATCGCAGCTGA
GGATATCTTGCATGATATGGGTGCTTTCTCAATTATTGCTAGTGATTCTCAAGCCATGGGAAGAGTTGGTGAAGTAATTA
CAAGAACTTTTCAAACCGCTCATAAAATGAAAGTTCAAAGGGGGCCGCTATCGCAGGATTCTGATATAAACGATAATTAC
AGAGTAAAGAGATATATTTCAAAAGTCACAATTAATCCTGCAATAGCTCATGGTATTGATAAACATGTTGGGTCTATAGA
AAAGGGTAAAATTGCGGATTTGGCATTGTGGAAACCATCCTTTTTTGCGGTAAAGCCTGAATTAGTTGTTAAAGGAGGAT
CTATCGTTTGGTCCCAGATGGGTGATGCAAATGCTTCAATTCCTACTCCAGGTCCTGTACATGGTCGACCTATGTTTGCA
AGTTTCGGCCAATCTCTTATTAAGAGTTCTTTTACCTTTTTAAGTAAAAATTCAATTGATCAAAATATTCCAAATAAATT
AGGCTTACAAAAGAAATGTATTGCTGTAGAAAATACAAGAAATATCAATAAATCACACTTAAAACTTAATAGTAAACTTC
CAAATATTTCAGTTGATCCTCAAACTTATGAAGTTTTTTCTGATGGGGAACTTCTTACTTGTGAACCCCTTGATGAAGTT
CCAATGGCTCAAAGGTACTTTTTACTTTAG

Upstream 100 bases:

>100_bases
CCTGGAGACACAACTGATGTCAAATTAGTTCCATATAAAGGTTTAAGAATTGCATATGGTTTTAATTCATTGGTTAACGG
TTCTTTAGATACTTAAAATT

Downstream 100 bases:

>100_bases
AAGTTTTTAATTAATTCTTTTTTAGTTGTTTTTATATCTTGTGACCCAGCAATTGCCAAATCTTCTTGCAGTTTGTCCTC
ACAAGATAGAACTCTTGACC

Product: urease subunit alpha

Products: NA

Alternate protein names: Urea amidohydrolase subunit alpha

Number of amino acids: Translated: 569; Mature: 568

Protein sequence:

>569_residues
MSYKIDRNTYAQTFGPTTGDRVRLADTELFIEVEKDLTTYGDEVKFGGGKVIRDGMGQSQVRRADGAVDTVITNALIVDW
WGIIKADVGIKDGMIFEIGKAGNPDIQDNVDIVIGASTEVIAGEGHILTAGSIDTHIHFICPQQIETALASGITTMLGGG
TGPATGTNATTCTPGSFHISRMLQSAEAFPMNLGFFGKGNSTNETNLIDQVEAGACGLKLHEDWGTTPSTINSCLNVADK
FDVQVCIHTDTLNEAGFVEDTINAIAGRTIHTFHTEGAGGGHAPDIIKICGEKNVLPSSTNPTRPYTRNTLEEHLDMLMV
CHHLDSKIPEDIAFAESRIRRETIAAEDILHDMGAFSIIASDSQAMGRVGEVITRTFQTAHKMKVQRGPLSQDSDINDNY
RVKRYISKVTINPAIAHGIDKHVGSIEKGKIADLALWKPSFFAVKPELVVKGGSIVWSQMGDANASIPTPGPVHGRPMFA
SFGQSLIKSSFTFLSKNSIDQNIPNKLGLQKKCIAVENTRNINKSHLKLNSKLPNISVDPQTYEVFSDGELLTCEPLDEV
PMAQRYFLL

Sequences:

>Translated_569_residues
MSYKIDRNTYAQTFGPTTGDRVRLADTELFIEVEKDLTTYGDEVKFGGGKVIRDGMGQSQVRRADGAVDTVITNALIVDW
WGIIKADVGIKDGMIFEIGKAGNPDIQDNVDIVIGASTEVIAGEGHILTAGSIDTHIHFICPQQIETALASGITTMLGGG
TGPATGTNATTCTPGSFHISRMLQSAEAFPMNLGFFGKGNSTNETNLIDQVEAGACGLKLHEDWGTTPSTINSCLNVADK
FDVQVCIHTDTLNEAGFVEDTINAIAGRTIHTFHTEGAGGGHAPDIIKICGEKNVLPSSTNPTRPYTRNTLEEHLDMLMV
CHHLDSKIPEDIAFAESRIRRETIAAEDILHDMGAFSIIASDSQAMGRVGEVITRTFQTAHKMKVQRGPLSQDSDINDNY
RVKRYISKVTINPAIAHGIDKHVGSIEKGKIADLALWKPSFFAVKPELVVKGGSIVWSQMGDANASIPTPGPVHGRPMFA
SFGQSLIKSSFTFLSKNSIDQNIPNKLGLQKKCIAVENTRNINKSHLKLNSKLPNISVDPQTYEVFSDGELLTCEPLDEV
PMAQRYFLL
>Mature_568_residues
SYKIDRNTYAQTFGPTTGDRVRLADTELFIEVEKDLTTYGDEVKFGGGKVIRDGMGQSQVRRADGAVDTVITNALIVDWW
GIIKADVGIKDGMIFEIGKAGNPDIQDNVDIVIGASTEVIAGEGHILTAGSIDTHIHFICPQQIETALASGITTMLGGGT
GPATGTNATTCTPGSFHISRMLQSAEAFPMNLGFFGKGNSTNETNLIDQVEAGACGLKLHEDWGTTPSTINSCLNVADKF
DVQVCIHTDTLNEAGFVEDTINAIAGRTIHTFHTEGAGGGHAPDIIKICGEKNVLPSSTNPTRPYTRNTLEEHLDMLMVC
HHLDSKIPEDIAFAESRIRRETIAAEDILHDMGAFSIIASDSQAMGRVGEVITRTFQTAHKMKVQRGPLSQDSDINDNYR
VKRYISKVTINPAIAHGIDKHVGSIEKGKIADLALWKPSFFAVKPELVVKGGSIVWSQMGDANASIPTPGPVHGRPMFAS
FGQSLIKSSFTFLSKNSIDQNIPNKLGLQKKCIAVENTRNINKSHLKLNSKLPNISVDPQTYEVFSDGELLTCEPLDEVP
MAQRYFLL

Specific function: Unknown

COG id: COG0804

COG function: function code E; Urea amidohydrolase (urease) alpha subunit

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 urease domain

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): URE1_PROM0 (A3PCP1)

Other databases:

- EMBL:   CP000576
- RefSeq:   YP_001091117.1
- ProteinModelPortal:   A3PCP1
- SMR:   A3PCP1
- STRING:   A3PCP1
- GeneID:   4912377
- GenomeReviews:   CP000576_GR
- KEGG:   pmg:P9301_08931
- eggNOG:   COG0804
- HOGENOM:   HBG357507
- OMA:   TIHAFHT
- ProtClustDB:   PRK13207
- BioCyc:   PMAR167546:P9301ORF_0910-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_01953
- InterPro:   IPR006680
- InterPro:   IPR011059
- InterPro:   IPR011612
- InterPro:   IPR005848
- InterPro:   IPR017951
- InterPro:   IPR017950
- PRINTS:   PR01752
- TIGRFAMs:   TIGR01792

Pfam domain/function: PF01979 Amidohydro_1; PF00449 Urease_alpha; SSF51338 Metalo_hydrolase

EC number: =3.5.1.5

Molecular weight: Translated: 61668; Mature: 61536

Theoretical pI: Translated: 5.81; Mature: 5.81

Prosite motif: PS01120 UREASE_1; PS00145 UREASE_2; PS51368 UREASE_3

Important sites: ACT_SITE 322-322 BINDING 221-221

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSYKIDRNTYAQTFGPTTGDRVRLADTELFIEVEKDLTTYGDEVKFGGGKVIRDGMGQSQ
CCEECCCCCHHHHCCCCCCCEEEEECCEEEEEECCHHHCCCCEEEECCCEEEECCCCHHH
VRRADGAVDTVITNALIVDWWGIIKADVGIKDGMIFEIGKAGNPDIQDNVDIVIGASTEV
HHHHCCHHHHHHHHHHHEEHHHHEEECCCCCCCEEEEECCCCCCCCCCCCCEEEECCCEE
IAGEGHILTAGSIDTHIHFICPQQIETALASGITTMLGGGTGPATGTNATTCTPGSFHIS
EECCCCEEEECCCCCEEEEECHHHHHHHHHHCHHHHHCCCCCCCCCCCCCEECCCHHHHH
RMLQSAEAFPMNLGFFGKGNSTNETNLIDQVEAGACGLKLHEDWGTTPSTINSCLNVADK
HHHHHHCCCCCCEEEECCCCCCCCCHHHHHHCCCCCCEEEECCCCCCHHHHHHHHHHHCC
FDVQVCIHTDTLNEAGFVEDTINAIAGRTIHTFHTEGAGGGHAPDIIKICGEKNVLPSST
CCEEEEEEECCCCCCCCHHHHHHHHCCCEEEEEECCCCCCCCCCHHHHHCCCCCCCCCCC
NPTRPYTRNTLEEHLDMLMVCHHLDSKIPEDIAFAESRIRRETIAAEDILHDMGAFSIIA
CCCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEE
SDSQAMGRVGEVITRTFQTAHKMKVQRGPLSQDSDINDNYRVKRYISKVTINPAIAHGID
CCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHCCCHHHHHHHH
KHVGSIEKGKIADLALWKPSFFAVKPELVVKGGSIVWSQMGDANASIPTPGPVHGRPMFA
HHHCCCCCCCEEEEEEECCCEEEECCEEEEECCCEEEECCCCCCCCCCCCCCCCCCCHHH
SFGQSLIKSSFTFLSKNSIDQNIPNKLGLQKKCIAVENTRNINKSHLKLNSKLPNISVDP
HHHHHHHHHHHHHHHCCCCCCCCCHHHCCCCEEEEECCCCCCCHHHEEECCCCCCCCCCC
QTYEVFSDGELLTCEPLDEVPMAQRYFLL
CEEEEECCCCEEEECCCCCCCCCHHHCCC
>Mature Secondary Structure 
SYKIDRNTYAQTFGPTTGDRVRLADTELFIEVEKDLTTYGDEVKFGGGKVIRDGMGQSQ
CEECCCCCHHHHCCCCCCCEEEEECCEEEEEECCHHHCCCCEEEECCCEEEECCCCHHH
VRRADGAVDTVITNALIVDWWGIIKADVGIKDGMIFEIGKAGNPDIQDNVDIVIGASTEV
HHHHCCHHHHHHHHHHHEEHHHHEEECCCCCCCEEEEECCCCCCCCCCCCCEEEECCCEE
IAGEGHILTAGSIDTHIHFICPQQIETALASGITTMLGGGTGPATGTNATTCTPGSFHIS
EECCCCEEEECCCCCEEEEECHHHHHHHHHHCHHHHHCCCCCCCCCCCCCEECCCHHHHH
RMLQSAEAFPMNLGFFGKGNSTNETNLIDQVEAGACGLKLHEDWGTTPSTINSCLNVADK
HHHHHHCCCCCCEEEECCCCCCCCCHHHHHHCCCCCCEEEECCCCCCHHHHHHHHHHHCC
FDVQVCIHTDTLNEAGFVEDTINAIAGRTIHTFHTEGAGGGHAPDIIKICGEKNVLPSST
CCEEEEEEECCCCCCCCHHHHHHHHCCCEEEEEECCCCCCCCCCHHHHHCCCCCCCCCCC
NPTRPYTRNTLEEHLDMLMVCHHLDSKIPEDIAFAESRIRRETIAAEDILHDMGAFSIIA
CCCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEE
SDSQAMGRVGEVITRTFQTAHKMKVQRGPLSQDSDINDNYRVKRYISKVTINPAIAHGID
CCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHCCCHHHHHHHH
KHVGSIEKGKIADLALWKPSFFAVKPELVVKGGSIVWSQMGDANASIPTPGPVHGRPMFA
HHHCCCCCCCEEEEEEECCCEEEECCEEEEECCCEEEECCCCCCCCCCCCCCCCCCCHHH
SFGQSLIKSSFTFLSKNSIDQNIPNKLGLQKKCIAVENTRNINKSHLKLNSKLPNISVDP
HHHHHHHHHHHHHHHCCCCCCCCCHHHCCCCEEEEECCCCCCCHHHEEECCCCCCCCCCC
QTYEVFSDGELLTCEPLDEVPMAQRYFLL
CEEEEECCCCEEEECCCCCCCCCHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA