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The map label for this gene is purQ [H]

Identifier: 126696179

GI number: 126696179

Start: 729485

End: 730150

Strand: Direct

Name: purQ [H]

Synonym: P9301_08411

Alternate gene names: 126696179

Gene position: 729485-730150 (Clockwise)

Preceding gene: 126696178

Following gene: 126696196

Centisome position: 44.43

GC content: 35.74

Gene sequence:

>666_bases
ATGGATAATTTTACTGTAGGAGTTGTTGTCTTCCCTGGTTCTAATTGTGATCGTGACGTTTCATGGGCATTGGAAGGTTG
TTTAGACATAAGAACAAAATACTTGTGGCATGAGTCATCAGATTTAAGCGATGTAGATGCAATAGTTTTACCCGGAGGAT
TTAGCTATGGTGATTATTTAAGATGTGGAGCAATAGCGAGATTCTCTCCATTAATAAATGCTTTGGATGACTTTGTGAAA
AGTGGAAGAAGAGTTTTAGGAATTTGTAATGGGTTCCAAATTTTGACAGAATCAGGCTTTTTGCCTGGTGCCCTTACTGC
AAATAAAAATCTTAATTTCATCTGTGATGATGTTGAACTTGATATTGTTTCTTCAAAAGGAGGTTGGTTCAATGATGGAG
GTGAAAAACAAACTATTAAGTTACCCATAGCGCATGGGGAAGGAAGATTTCATTGTGATTCTGATACTTTAAAAAAACTT
GTAGATAATGAATTGATCGCCTTGAGATATAAAAATAATCCTAATGGCTCCTCATTCGATATCGCAGGCATAACTAATGA
AAAGGGTAATGTTCTTGGTTTAATGCCTCATCCAGAACGAGCATGTGACGAGACAATTGGTGGGACTGATGGTCTCTTTA
CATTAAAATCATTAATATTGAAATAA

Upstream 100 bases:

>100_bases
GGTGAAAACGAAGTAAGAGAAAAAATTGATTTATTGTGTGATAGGTTATTCGCAAATACTGTTATTGAAGATTACGAGTA
TTCACTAGAAAAATTATAAG

Downstream 100 bases:

>100_bases
AAAAGACCCCCAATTTTGGGGGTCTTTTTTATTTAATATGGGAAGAAATTAGACAGTAGCTTTTACTTTTGGATCTAAAT
CACCTTTAGCGTAAAGATCC

Product: phosphoribosylformylglycinamidine synthase I

Products: NA

Alternate protein names: Phosphoribosylformylglycinamidine synthase I; FGAM synthase I [H]

Number of amino acids: Translated: 221; Mature: 221

Protein sequence:

>221_residues
MDNFTVGVVVFPGSNCDRDVSWALEGCLDIRTKYLWHESSDLSDVDAIVLPGGFSYGDYLRCGAIARFSPLINALDDFVK
SGRRVLGICNGFQILTESGFLPGALTANKNLNFICDDVELDIVSSKGGWFNDGGEKQTIKLPIAHGEGRFHCDSDTLKKL
VDNELIALRYKNNPNGSSFDIAGITNEKGNVLGLMPHPERACDETIGGTDGLFTLKSLILK

Sequences:

>Translated_221_residues
MDNFTVGVVVFPGSNCDRDVSWALEGCLDIRTKYLWHESSDLSDVDAIVLPGGFSYGDYLRCGAIARFSPLINALDDFVK
SGRRVLGICNGFQILTESGFLPGALTANKNLNFICDDVELDIVSSKGGWFNDGGEKQTIKLPIAHGEGRFHCDSDTLKKL
VDNELIALRYKNNPNGSSFDIAGITNEKGNVLGLMPHPERACDETIGGTDGLFTLKSLILK
>Mature_221_residues
MDNFTVGVVVFPGSNCDRDVSWALEGCLDIRTKYLWHESSDLSDVDAIVLPGGFSYGDYLRCGAIARFSPLINALDDFVK
SGRRVLGICNGFQILTESGFLPGALTANKNLNFICDDVELDIVSSKGGWFNDGGEKQTIKLPIAHGEGRFHCDSDTLKKL
VDNELIALRYKNNPNGSSFDIAGITNEKGNVLGLMPHPERACDETIGGTDGLFTLKSLILK

Specific function: Unknown

COG id: COG0047

COG function: function code F; Phosphoribosylformylglycinamidine (FGAM) synthase, glutamine amidotransferase domain

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 glutamine amidotransferase type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI48994899, Length=196, Percent_Identity=32.1428571428571, Blast_Score=76, Evalue=1e-15,
Organism=Saccharomyces cerevisiae, GI6321498, Length=237, Percent_Identity=27.8481012658228, Blast_Score=74, Evalue=1e-14,
Organism=Drosophila melanogaster, GI24582111, Length=234, Percent_Identity=31.1965811965812, Blast_Score=78, Evalue=6e-15,
Organism=Drosophila melanogaster, GI24582109, Length=234, Percent_Identity=31.1965811965812, Blast_Score=78, Evalue=6e-15,
Organism=Drosophila melanogaster, GI17137292, Length=234, Percent_Identity=31.1965811965812, Blast_Score=78, Evalue=6e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017926
- InterPro:   IPR011698
- InterPro:   IPR010075 [H]

Pfam domain/function: PF07685 GATase_3 [H]

EC number: =6.3.5.3 [H]

Molecular weight: Translated: 24036; Mature: 24036

Theoretical pI: Translated: 4.67; Mature: 4.67

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.2 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
3.2 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDNFTVGVVVFPGSNCDRDVSWALEGCLDIRTKYLWHESSDLSDVDAIVLPGGFSYGDYL
CCCEEEEEEEECCCCCCCCHHHHHHHHHHHHHHHEECCCCCCCCCCEEEECCCCCCCCHH
RCGAIARFSPLINALDDFVKSGRRVLGICNGFQILTESGFLPGALTANKNLNFICDDVEL
HHCHHHHHHHHHHHHHHHHHCCCEEEEEECCEEEEECCCCCCCEEECCCCCCEEECCEEE
DIVSSKGGWFNDGGEKQTIKLPIAHGEGRFHCDSDTLKKLVDNELIALRYKNNPNGSSFD
EEEECCCCCCCCCCCCEEEEEEEECCCCEEEECHHHHHHHHCCCEEEEEECCCCCCCEEE
IAGITNEKGNVLGLMPHPERACDETIGGTDGLFTLKSLILK
EEEEECCCCCEEEECCCCHHHHHHHCCCCCHHHHHHHHHCC
>Mature Secondary Structure
MDNFTVGVVVFPGSNCDRDVSWALEGCLDIRTKYLWHESSDLSDVDAIVLPGGFSYGDYL
CCCEEEEEEEECCCCCCCCHHHHHHHHHHHHHHHEECCCCCCCCCCEEEECCCCCCCCHH
RCGAIARFSPLINALDDFVKSGRRVLGICNGFQILTESGFLPGALTANKNLNFICDDVEL
HHCHHHHHHHHHHHHHHHHHCCCEEEEEECCEEEEECCCCCCCEEECCCCCCEEECCEEE
DIVSSKGGWFNDGGEKQTIKLPIAHGEGRFHCDSDTLKKLVDNELIALRYKNNPNGSSFD
EEEECCCCCCCCCCCCEEEEEEEECCCCEEEECHHHHHHHHCCCEEEEEECCCCCCCEEE
IAGITNEKGNVLGLMPHPERACDETIGGTDGLFTLKSLILK
EEEEECCCCCEEEECCCCHHHHHHHCCCCCHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA