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The map label for this gene is typA [H]

Identifier: 126696160

GI number: 126696160

Start: 712663

End: 714459

Strand: Direct

Name: typA [H]

Synonym: P9301_08221

Alternate gene names: 126696160

Gene position: 712663-714459 (Clockwise)

Preceding gene: 126696159

Following gene: 126696161

Centisome position: 43.41

GC content: 35.89

Gene sequence:

>1797_bases
ATGTCATCTTCGATAAAAGAAATTAGAAATGTTGCAATTATTGCTCACGTAGATCATGGCAAGACAACGCTTGTAGATGC
ATTGTTATCTCAATCAGGAATATTTAGAGACAATGAAGTTATCCCTACATGTGTAATGGATTCAAACGATCTTGAAAGAG
AAAGGGGGATAACAATTCTCTCAAAAAATACTGCAGTTAACTATAAAGATACCAGAATTAATATTATAGATACACCTGGA
CATGCTGATTTTGGAGGAGAAGTTGAGAGGGTTTTGGGAATGGTTGATGGTTGTCTGCTTATTGTTGATGCAAATGAGGG
ACCTATGCCTCAAACAAGATTTGTTTTAAAAAAAGCATTAGAAAAAGGACTTAGGCCTATAGTCTTTGTAAATAAAATTG
ATAGACCACGAGTAGTGCCAGAACTAGCAATTGATAAGGTCCTTGATTTGTTTTTGGAATTAGGAGCTGATGATGATCAA
TGTGATTTTCCTTATCTTTTTGGGAGTGGCTTATCTGGTTTCGCAAAAGAAGAGATGGAATCTAATAGTGACAATATGAT
GCCTCTTTTTGAAGCTATTATAAGACATGTTCCTCCTCCAGTAGGTGACTCTAATAAGCCTCTTCAGCTACAAATAACTA
CCTTGGACTATTCTGATTTCTTGGGCAGAATAGTAATTGGAAAGATCCACAATGGAACTATAAAAAATGGCCAACAGGCT
AGTTTAATTAAAGAAAACGGAAAAACTATTAAAGGTAAGGTTAGTAAGCTTTTAGGATTTGAAGGATTACAAAGAATTGA
TATAAATGAAGCATTTGCAGGAGATATTGTTGCTGTTTCTGGTTTTGATGACGTCAATATTGGTGAGACCATAGCATGTC
CCGATTCTCCTCATCCTCTCCCATTAATCAAAGTTGATGAACCTACCTTAAATATGACTTTTGTTGTCAATGATTCACCA
TTCGCGGGAAAGGAAGGGAAATTTGTTACCAGTAGACAATTAAAAAATAGATTGGAGAGGGAACTTCTAACAAATGTTGC
CCTAAGAGTAGAAGAAACTGATTCTCCTGACAGGTTCTCAGTTTCAGGAAGAGGAGAATTACATCTAGGGATATTGATTG
AAACCATGAGAAGAGAGGGTTTTGAGTTCCAAATATCACAACCTCAAGTAATTTTCAGAGAAATTGATAACGTTGAATGT
GAGCCTATAGAGACTTTGGTTTTAGATGTGCCTGAAGTATCTGTTGGTTCTTGCATCGAAAAACTTGGATCTAGAAAGGC
AGAGATGAAAAACATGCAGACAAGTTCAGATGGTAGAACTCAATTAGAATTTCTTGTTCCATCAAGAGGATTAATCGGAT
TTCGTGGGGAATTTGTAAGGATAACCAGAGGTGAAGGCATCATGAGCCACTCATTTTATGAATATAAACCTAAAACAGGA
GATTTTGAAACCAGGAGAAACGGAGTCCTTATAGCTTTTGAAGAAGGTGTTGCCACATTTTATGCATTAAAGAATGCTGA
AGATAGGGGAGTCTATTTCATTAAACCTGGAGTCAAAGTTTATAAGGGGATGATAATTGGAGAGAATAATCGACCGCAAG
ATCTTGAGTTGAATATATGTAAAACTAAGCAGTTGACTAATATGAGGTCTGCAGGAGCAGAAGAACTTGATACTTTGCAG
TCACCTGTTGATATTACCCTTGAAAGAGCACTCGAATATATTGGTCCAGATGAAATGCTAGAGGTAACACCAGATTCAAT
AAGAATGAGAAAAATTAATAAAAAGAAAAAAAATTAA

Upstream 100 bases:

>100_bases
AGATTATTTTTTTCAAAGTCTTAAAAAGAAAATTTTCATAATAAGCATACTTTGAGTTAGCCTTAATAAAGTCAAACTTC
TATTTATATAAATTCTATAA

Downstream 100 bases:

>100_bases
TTATTAGTTTCATGAATGAAGAAAGTACAAAAAGTTTTAAAGATTCCCTTTTTACTGCTTTAACTCTTTTTAATAATCAT
GAATGGTATGAGGCTCATGA

Product: tyrosine binding protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 598; Mature: 597

Protein sequence:

>598_residues
MSSSIKEIRNVAIIAHVDHGKTTLVDALLSQSGIFRDNEVIPTCVMDSNDLERERGITILSKNTAVNYKDTRINIIDTPG
HADFGGEVERVLGMVDGCLLIVDANEGPMPQTRFVLKKALEKGLRPIVFVNKIDRPRVVPELAIDKVLDLFLELGADDDQ
CDFPYLFGSGLSGFAKEEMESNSDNMMPLFEAIIRHVPPPVGDSNKPLQLQITTLDYSDFLGRIVIGKIHNGTIKNGQQA
SLIKENGKTIKGKVSKLLGFEGLQRIDINEAFAGDIVAVSGFDDVNIGETIACPDSPHPLPLIKVDEPTLNMTFVVNDSP
FAGKEGKFVTSRQLKNRLERELLTNVALRVEETDSPDRFSVSGRGELHLGILIETMRREGFEFQISQPQVIFREIDNVEC
EPIETLVLDVPEVSVGSCIEKLGSRKAEMKNMQTSSDGRTQLEFLVPSRGLIGFRGEFVRITRGEGIMSHSFYEYKPKTG
DFETRRNGVLIAFEEGVATFYALKNAEDRGVYFIKPGVKVYKGMIIGENNRPQDLELNICKTKQLTNMRSAGAEELDTLQ
SPVDITLERALEYIGPDEMLEVTPDSIRMRKINKKKKN

Sequences:

>Translated_598_residues
MSSSIKEIRNVAIIAHVDHGKTTLVDALLSQSGIFRDNEVIPTCVMDSNDLERERGITILSKNTAVNYKDTRINIIDTPG
HADFGGEVERVLGMVDGCLLIVDANEGPMPQTRFVLKKALEKGLRPIVFVNKIDRPRVVPELAIDKVLDLFLELGADDDQ
CDFPYLFGSGLSGFAKEEMESNSDNMMPLFEAIIRHVPPPVGDSNKPLQLQITTLDYSDFLGRIVIGKIHNGTIKNGQQA
SLIKENGKTIKGKVSKLLGFEGLQRIDINEAFAGDIVAVSGFDDVNIGETIACPDSPHPLPLIKVDEPTLNMTFVVNDSP
FAGKEGKFVTSRQLKNRLERELLTNVALRVEETDSPDRFSVSGRGELHLGILIETMRREGFEFQISQPQVIFREIDNVEC
EPIETLVLDVPEVSVGSCIEKLGSRKAEMKNMQTSSDGRTQLEFLVPSRGLIGFRGEFVRITRGEGIMSHSFYEYKPKTG
DFETRRNGVLIAFEEGVATFYALKNAEDRGVYFIKPGVKVYKGMIIGENNRPQDLELNICKTKQLTNMRSAGAEELDTLQ
SPVDITLERALEYIGPDEMLEVTPDSIRMRKINKKKKN
>Mature_597_residues
SSSIKEIRNVAIIAHVDHGKTTLVDALLSQSGIFRDNEVIPTCVMDSNDLERERGITILSKNTAVNYKDTRINIIDTPGH
ADFGGEVERVLGMVDGCLLIVDANEGPMPQTRFVLKKALEKGLRPIVFVNKIDRPRVVPELAIDKVLDLFLELGADDDQC
DFPYLFGSGLSGFAKEEMESNSDNMMPLFEAIIRHVPPPVGDSNKPLQLQITTLDYSDFLGRIVIGKIHNGTIKNGQQAS
LIKENGKTIKGKVSKLLGFEGLQRIDINEAFAGDIVAVSGFDDVNIGETIACPDSPHPLPLIKVDEPTLNMTFVVNDSPF
AGKEGKFVTSRQLKNRLERELLTNVALRVEETDSPDRFSVSGRGELHLGILIETMRREGFEFQISQPQVIFREIDNVECE
PIETLVLDVPEVSVGSCIEKLGSRKAEMKNMQTSSDGRTQLEFLVPSRGLIGFRGEFVRITRGEGIMSHSFYEYKPKTGD
FETRRNGVLIAFEEGVATFYALKNAEDRGVYFIKPGVKVYKGMIIGENNRPQDLELNICKTKQLTNMRSAGAEELDTLQS
PVDITLERALEYIGPDEMLEVTPDSIRMRKINKKKKN

Specific function: Not known; probably interacts with the ribosomes in a GTP dependent manner [H]

COG id: COG1217

COG function: function code T; Predicted membrane GTPase involved in stress response

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GTP-binding elongation factor family. TypA subfamily [H]

Homologues:

Organism=Homo sapiens, GI94966754, Length=132, Percent_Identity=45.4545454545455, Blast_Score=125, Evalue=1e-28,
Organism=Homo sapiens, GI157426893, Length=493, Percent_Identity=26.9776876267748, Blast_Score=125, Evalue=1e-28,
Organism=Homo sapiens, GI34147630, Length=299, Percent_Identity=30.7692307692308, Blast_Score=110, Evalue=4e-24,
Organism=Homo sapiens, GI18390331, Length=147, Percent_Identity=43.5374149659864, Blast_Score=107, Evalue=3e-23,
Organism=Homo sapiens, GI4503483, Length=144, Percent_Identity=38.1944444444444, Blast_Score=102, Evalue=1e-21,
Organism=Homo sapiens, GI25306287, Length=145, Percent_Identity=38.6206896551724, Blast_Score=101, Evalue=3e-21,
Organism=Homo sapiens, GI25306283, Length=145, Percent_Identity=38.6206896551724, Blast_Score=101, Evalue=3e-21,
Organism=Homo sapiens, GI19923640, Length=145, Percent_Identity=38.6206896551724, Blast_Score=100, Evalue=3e-21,
Organism=Homo sapiens, GI310132016, Length=110, Percent_Identity=43.6363636363636, Blast_Score=95, Evalue=2e-19,
Organism=Homo sapiens, GI310110807, Length=110, Percent_Identity=43.6363636363636, Blast_Score=95, Evalue=2e-19,
Organism=Homo sapiens, GI310123363, Length=110, Percent_Identity=43.6363636363636, Blast_Score=95, Evalue=2e-19,
Organism=Homo sapiens, GI217272894, Length=134, Percent_Identity=40.2985074626866, Blast_Score=88, Evalue=3e-17,
Organism=Homo sapiens, GI217272892, Length=134, Percent_Identity=40.2985074626866, Blast_Score=88, Evalue=3e-17,
Organism=Homo sapiens, GI94966752, Length=128, Percent_Identity=32.03125, Blast_Score=79, Evalue=1e-14,
Organism=Homo sapiens, GI53729339, Length=294, Percent_Identity=26.530612244898, Blast_Score=69, Evalue=1e-11,
Organism=Homo sapiens, GI53729337, Length=294, Percent_Identity=26.530612244898, Blast_Score=69, Evalue=1e-11,
Organism=Escherichia coli, GI48994988, Length=588, Percent_Identity=54.0816326530612, Blast_Score=641, Evalue=0.0,
Organism=Escherichia coli, GI1788922, Length=545, Percent_Identity=26.7889908256881, Blast_Score=140, Evalue=3e-34,
Organism=Escherichia coli, GI1789738, Length=143, Percent_Identity=41.2587412587413, Blast_Score=97, Evalue=2e-21,
Organism=Escherichia coli, GI1789737, Length=298, Percent_Identity=28.5234899328859, Blast_Score=86, Evalue=5e-18,
Organism=Escherichia coli, GI1790412, Length=298, Percent_Identity=28.8590604026846, Blast_Score=86, Evalue=5e-18,
Organism=Escherichia coli, GI1790835, Length=156, Percent_Identity=31.4102564102564, Blast_Score=82, Evalue=7e-17,
Organism=Caenorhabditis elegans, GI17557151, Length=233, Percent_Identity=34.7639484978541, Blast_Score=122, Evalue=4e-28,
Organism=Caenorhabditis elegans, GI17506493, Length=219, Percent_Identity=32.8767123287671, Blast_Score=109, Evalue=4e-24,
Organism=Caenorhabditis elegans, GI17556745, Length=143, Percent_Identity=39.8601398601399, Blast_Score=106, Evalue=4e-23,
Organism=Caenorhabditis elegans, GI17533571, Length=147, Percent_Identity=45.578231292517, Blast_Score=105, Evalue=6e-23,
Organism=Caenorhabditis elegans, GI71988811, Length=133, Percent_Identity=40.6015037593985, Blast_Score=105, Evalue=6e-23,
Organism=Caenorhabditis elegans, GI71988819, Length=133, Percent_Identity=40.6015037593985, Blast_Score=105, Evalue=7e-23,
Organism=Caenorhabditis elegans, GI17556456, Length=285, Percent_Identity=29.1228070175439, Blast_Score=98, Evalue=2e-20,
Organism=Caenorhabditis elegans, GI17552882, Length=178, Percent_Identity=33.7078651685393, Blast_Score=88, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI32566629, Length=266, Percent_Identity=28.1954887218045, Blast_Score=72, Evalue=6e-13,
Organism=Caenorhabditis elegans, GI25141371, Length=275, Percent_Identity=26.9090909090909, Blast_Score=69, Evalue=5e-12,
Organism=Caenorhabditis elegans, GI32566303, Length=263, Percent_Identity=28.1368821292776, Blast_Score=69, Evalue=7e-12,
Organism=Caenorhabditis elegans, GI71994658, Length=154, Percent_Identity=33.7662337662338, Blast_Score=66, Evalue=4e-11,
Organism=Saccharomyces cerevisiae, GI6323320, Length=501, Percent_Identity=27.1457085828343, Blast_Score=130, Evalue=8e-31,
Organism=Saccharomyces cerevisiae, GI6324761, Length=274, Percent_Identity=31.021897810219, Blast_Score=123, Evalue=8e-29,
Organism=Saccharomyces cerevisiae, GI6324707, Length=208, Percent_Identity=35.0961538461538, Blast_Score=108, Evalue=2e-24,
Organism=Saccharomyces cerevisiae, GI6320593, Length=208, Percent_Identity=35.0961538461538, Blast_Score=108, Evalue=2e-24,
Organism=Saccharomyces cerevisiae, GI6322359, Length=136, Percent_Identity=41.9117647058824, Blast_Score=98, Evalue=5e-21,
Organism=Saccharomyces cerevisiae, GI6323098, Length=153, Percent_Identity=39.2156862745098, Blast_Score=94, Evalue=5e-20,
Organism=Saccharomyces cerevisiae, GI6324166, Length=142, Percent_Identity=38.0281690140845, Blast_Score=89, Evalue=2e-18,
Organism=Drosophila melanogaster, GI78706572, Length=526, Percent_Identity=24.9049429657795, Blast_Score=113, Evalue=5e-25,
Organism=Drosophila melanogaster, GI281363316, Length=300, Percent_Identity=30, Blast_Score=110, Evalue=2e-24,
Organism=Drosophila melanogaster, GI17864358, Length=300, Percent_Identity=30, Blast_Score=110, Evalue=2e-24,
Organism=Drosophila melanogaster, GI28574573, Length=199, Percent_Identity=35.1758793969849, Blast_Score=107, Evalue=2e-23,
Organism=Drosophila melanogaster, GI24582462, Length=136, Percent_Identity=46.3235294117647, Blast_Score=107, Evalue=3e-23,
Organism=Drosophila melanogaster, GI24585711, Length=168, Percent_Identity=37.5, Blast_Score=107, Evalue=3e-23,
Organism=Drosophila melanogaster, GI24585713, Length=168, Percent_Identity=37.5, Blast_Score=107, Evalue=3e-23,
Organism=Drosophila melanogaster, GI24585709, Length=168, Percent_Identity=37.5, Blast_Score=107, Evalue=3e-23,
Organism=Drosophila melanogaster, GI19921738, Length=275, Percent_Identity=31.6363636363636, Blast_Score=99, Evalue=1e-20,
Organism=Drosophila melanogaster, GI221458488, Length=137, Percent_Identity=42.3357664233577, Blast_Score=91, Evalue=3e-18,
Organism=Drosophila melanogaster, GI21357743, Length=190, Percent_Identity=35.2631578947368, Blast_Score=89, Evalue=1e-17,
Organism=Drosophila melanogaster, GI17137380, Length=267, Percent_Identity=26.2172284644195, Blast_Score=68, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009022
- InterPro:   IPR000795
- InterPro:   IPR005225
- InterPro:   IPR000640
- InterPro:   IPR004161
- InterPro:   IPR009000
- InterPro:   IPR006298 [H]

Pfam domain/function: PF00679 EFG_C; PF00009 GTP_EFTU; PF03144 GTP_EFTU_D2 [H]

EC number: NA

Molecular weight: Translated: 66578; Mature: 66447

Theoretical pI: Translated: 4.97; Mature: 4.97

Prosite motif: PS00301 EFACTOR_GTP

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSSSIKEIRNVAIIAHVDHGKTTLVDALLSQSGIFRDNEVIPTCVMDSNDLERERGITIL
CCCHHHHHCCEEEEEEECCCHHHHHHHHHHHCCCCCCCCCCEEEEECCCCCHHHCCEEEE
SKNTAVNYKDTRINIIDTPGHADFGGEVERVLGMVDGCLLIVDANEGPMPQTRFVLKKAL
ECCCEEEEECCEEEEEECCCCCCCCHHHHHHHHHHCCEEEEEECCCCCCCHHHHHHHHHH
EKGLRPIVFVNKIDRPRVVPELAIDKVLDLFLELGADDDQCDFPYLFGSGLSGFAKEEME
HHCCCEEEEEECCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCEEECCCCCHHHHHHHH
SNSDNMMPLFEAIIRHVPPPVGDSNKPLQLQITTLDYSDFLGRIVIGKIHNGTIKNGQQA
CCCCCCHHHHHHHHHHCCCCCCCCCCCEEEEEEEECHHHHHCEEEEEEECCCCCCCCCCH
SLIKENGKTIKGKVSKLLGFEGLQRIDINEAFAGDIVAVSGFDDVNIGETIACPDSPHPL
HHHHHCCCEEHHHHHHHHCCCCCEEECCCCCCCCCEEEECCCCCCCCCCEEECCCCCCCE
PLIKVDEPTLNMTFVVNDSPFAGKEGKFVTSRQLKNRLERELLTNVALRVEETDSPDRFS
EEEEECCCCEEEEEEECCCCCCCCCCCEEHHHHHHHHHHHHHHHHHEEEEECCCCCCEEE
VSGRGELHLGILIETMRREGFEFQISQPQVIFREIDNVECEPIETLVLDVPEVSVGSCIE
ECCCCCEEEHHHHHHHHHCCCEEEECCCHHHHHHHCCCCCCCCEEEEEECCCCCHHHHHH
KLGSRKAEMKNMQTSSDGRTQLEFLVPSRGLIGFRGEFVRITRGEGIMSHSFYEYKPKTG
HHCCCHHHHHHCCCCCCCCEEEEEEECCCCCEEECCCEEEEECCCCEECCCEEEECCCCC
DFETRRNGVLIAFEEGVATFYALKNAEDRGVYFIKPGVKVYKGMIIGENNRPQDLELNIC
CCCCCCCCEEEEEECCCEEEEEECCCCCCCEEEECCCHHEEEEEEECCCCCCCCEEEEEE
KTKQLTNMRSAGAEELDTLQSPVDITLERALEYIGPDEMLEVTPDSIRMRKINKKKKN
CCHHHHHHHHCCHHHHHHHCCCHHHHHHHHHHHCCCCCEEECCCCHHHHHHHHHHCCC
>Mature Secondary Structure 
SSSIKEIRNVAIIAHVDHGKTTLVDALLSQSGIFRDNEVIPTCVMDSNDLERERGITIL
CCHHHHHCCEEEEEEECCCHHHHHHHHHHHCCCCCCCCCCEEEEECCCCCHHHCCEEEE
SKNTAVNYKDTRINIIDTPGHADFGGEVERVLGMVDGCLLIVDANEGPMPQTRFVLKKAL
ECCCEEEEECCEEEEEECCCCCCCCHHHHHHHHHHCCEEEEEECCCCCCCHHHHHHHHHH
EKGLRPIVFVNKIDRPRVVPELAIDKVLDLFLELGADDDQCDFPYLFGSGLSGFAKEEME
HHCCCEEEEEECCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCEEECCCCCHHHHHHHH
SNSDNMMPLFEAIIRHVPPPVGDSNKPLQLQITTLDYSDFLGRIVIGKIHNGTIKNGQQA
CCCCCCHHHHHHHHHHCCCCCCCCCCCEEEEEEEECHHHHHCEEEEEEECCCCCCCCCCH
SLIKENGKTIKGKVSKLLGFEGLQRIDINEAFAGDIVAVSGFDDVNIGETIACPDSPHPL
HHHHHCCCEEHHHHHHHHCCCCCEEECCCCCCCCCEEEECCCCCCCCCCEEECCCCCCCE
PLIKVDEPTLNMTFVVNDSPFAGKEGKFVTSRQLKNRLERELLTNVALRVEETDSPDRFS
EEEEECCCCEEEEEEECCCCCCCCCCCEEHHHHHHHHHHHHHHHHHEEEEECCCCCCEEE
VSGRGELHLGILIETMRREGFEFQISQPQVIFREIDNVECEPIETLVLDVPEVSVGSCIE
ECCCCCEEEHHHHHHHHHCCCEEEECCCHHHHHHHCCCCCCCCEEEEEECCCCCHHHHHH
KLGSRKAEMKNMQTSSDGRTQLEFLVPSRGLIGFRGEFVRITRGEGIMSHSFYEYKPKTG
HHCCCHHHHHHCCCCCCCCEEEEEEECCCCCEEECCCEEEEECCCCEECCCEEEECCCCC
DFETRRNGVLIAFEEGVATFYALKNAEDRGVYFIKPGVKVYKGMIIGENNRPQDLELNIC
CCCCCCCCEEEEEECCCEEEEEECCCCCCCEEEECCCHHEEEEEEECCCCCCCCEEEEEE
KTKQLTNMRSAGAEELDTLQSPVDITLERALEYIGPDEMLEVTPDSIRMRKINKKKKN
CCHHHHHHHHCCHHHHHHHCCCHHHHHHHHHHHCCCCCEEECCCCHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8905231 [H]