| Definition | Prochlorococcus marinus str. MIT 9301, complete genome. |
|---|---|
| Accession | NC_009091 |
| Length | 1,641,879 |
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The map label for this gene is dfp [H]
Identifier: 126695589
GI number: 126695589
Start: 234918
End: 236174
Strand: Reverse
Name: dfp [H]
Synonym: P9301_02511
Alternate gene names: 126695589
Gene position: 236174-234918 (Counterclockwise)
Preceding gene: 126695590
Following gene: 126695588
Centisome position: 14.38
GC content: 31.82
Gene sequence:
>1257_bases ATGAAAACTAAAAGTAATGACTCCAAAATAAAGGTTCTTTTATTAATAACGGGTAGTATTGCAGCTGTAAGAATTCCATT ATTAGTAAGCCAATTAGCGAAAGAAAATTATGAAATAAGATGCGTTTTATCTAAAAATGCAGAAAAATTAATAAAGCCGC TTTCTCTCTCTATCTTGAGTAGAAACCCTTGCATTTTAGAAGATGATCAATGGTCAAATAGTCAATCAACACCTCTTCAC ATAGAACTCAGTAATTGGGCTGATATTTTAATCATTGCGCCTTTAACAGCAACAACATTAGCAAAATGGGTAACTGGGAA TGCAGAGGGACTTATCCCAAGCATCTTAATAGCAAATATAAAGCCAATTATTGTTGCACCAGCAATGAATACACAAATGT GGCTAAATAAAGCTGTCCAAGAAAATTATAAGAATTTAAAAAATTACGAAAATGTTTTGTCTTTGCAACCAAGTGAAGGC CTCTTAGCATGTGATGCTATTGGCATCGGTAAGATTCCTCCAAATAATCTAATTCAATTAGCTCTTGAATTTATAGCTTT ACACAAACAAAATGAGTATCGCAAAGATTTACTTAATAAAGAAATTCTAATAACTGGAGGGTGCACCTCAGAGAAAATTG ATGCGGCAAGACATATTACCAACAGAAGTTCTGGAGCTATGGGCCTACTTCTTTCTCAAGTAGCGAGGTTCAGAGGAGCA CAAGTAAAATATGTCCATGGGCCATTGAAAATCGATAAGAATCTTACTGATGGAATAAAAAGATATGAAATTGAAACCAG TGTTGATTTAATTAGGGCTCTTGATAATGAAATATCAAATTGCGATTATTTTTTCATGAATGCAGCAGTCTCTGATTTTA AGATAACCTCAGATACTTCAGCTAAAATTCCAAAAAATAAAATTAATGAACATTTGAATCAAAACTTTGAGCTAGTCCCA GATATTTTAAAAACAATTAGTAAATCAAAAAAAGATAACCAAGTTTTTGTAGGCTTTTGTGCTTTTACAGGATCTATCGA AGAAGCACGAATAACTATTAAAGAAAAGATTATCCAAAAGGGTTGTGATTTTCTATTCGCAAATCCAATAGATCTTGAAG GCCAAGGATTTGGCTTTTTGGCACAAAATGAAGGTTGGCTATTCGATACGAACAATTTGGAACACTATATTAAAAAAACA TCAAAAATTGATTTAGCAAATAAATTAATAACCCAAATTATTTCATTAAAAAAATAA
Upstream 100 bases:
>100_bases TTTGATGGTTTAAAAGACTGGCACTTACTTAGGGCTCTTGCAATCAATAGACCTGAATTAACAACTAATTATATCCATCT TCTCGATCAGGAACCTTTCG
Downstream 100 bases:
>100_bases AAAAAAATTTTTTATTTGTATTTTTTTGTAATCTTAATCATTAAAAATAATGTAATAGCTTAAAATAATTCCAGTTTTTC AAAATCTAAAAAGCTACGGG
Product: putative p-pantothenate cysteine ligase and p-pantothenenoylcysteine decarboxylase
Products: NA
Alternate protein names: DNA/pantothenate metabolism flavoprotein; Phosphopantothenoylcysteine decarboxylase; PPCDC; CoaC; Phosphopantothenate--cysteine ligase; CoaB; PPC synthetase; PPCS; Phosphopantothenoylcysteine synthase [H]
Number of amino acids: Translated: 418; Mature: 418
Protein sequence:
>418_residues MKTKSNDSKIKVLLLITGSIAAVRIPLLVSQLAKENYEIRCVLSKNAEKLIKPLSLSILSRNPCILEDDQWSNSQSTPLH IELSNWADILIIAPLTATTLAKWVTGNAEGLIPSILIANIKPIIVAPAMNTQMWLNKAVQENYKNLKNYENVLSLQPSEG LLACDAIGIGKIPPNNLIQLALEFIALHKQNEYRKDLLNKEILITGGCTSEKIDAARHITNRSSGAMGLLLSQVARFRGA QVKYVHGPLKIDKNLTDGIKRYEIETSVDLIRALDNEISNCDYFFMNAAVSDFKITSDTSAKIPKNKINEHLNQNFELVP DILKTISKSKKDNQVFVGFCAFTGSIEEARITIKEKIIQKGCDFLFANPIDLEGQGFGFLAQNEGWLFDTNNLEHYIKKT SKIDLANKLITQIISLKK
Sequences:
>Translated_418_residues MKTKSNDSKIKVLLLITGSIAAVRIPLLVSQLAKENYEIRCVLSKNAEKLIKPLSLSILSRNPCILEDDQWSNSQSTPLH IELSNWADILIIAPLTATTLAKWVTGNAEGLIPSILIANIKPIIVAPAMNTQMWLNKAVQENYKNLKNYENVLSLQPSEG LLACDAIGIGKIPPNNLIQLALEFIALHKQNEYRKDLLNKEILITGGCTSEKIDAARHITNRSSGAMGLLLSQVARFRGA QVKYVHGPLKIDKNLTDGIKRYEIETSVDLIRALDNEISNCDYFFMNAAVSDFKITSDTSAKIPKNKINEHLNQNFELVP DILKTISKSKKDNQVFVGFCAFTGSIEEARITIKEKIIQKGCDFLFANPIDLEGQGFGFLAQNEGWLFDTNNLEHYIKKT SKIDLANKLITQIISLKK >Mature_418_residues MKTKSNDSKIKVLLLITGSIAAVRIPLLVSQLAKENYEIRCVLSKNAEKLIKPLSLSILSRNPCILEDDQWSNSQSTPLH IELSNWADILIIAPLTATTLAKWVTGNAEGLIPSILIANIKPIIVAPAMNTQMWLNKAVQENYKNLKNYENVLSLQPSEG LLACDAIGIGKIPPNNLIQLALEFIALHKQNEYRKDLLNKEILITGGCTSEKIDAARHITNRSSGAMGLLLSQVARFRGA QVKYVHGPLKIDKNLTDGIKRYEIETSVDLIRALDNEISNCDYFFMNAAVSDFKITSDTSAKIPKNKINEHLNQNFELVP DILKTISKSKKDNQVFVGFCAFTGSIEEARITIKEKIIQKGCDFLFANPIDLEGQGFGFLAQNEGWLFDTNNLEHYIKKT SKIDLANKLITQIISLKK
Specific function: Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine [H]
COG id: COG0452
COG function: function code H; Phosphopantothenoylcysteine synthetase/decarboxylase
Gene ontology:
Cell location: Cytoplasm [C]
Metaboloic importance: Essential [C]
Operon status: Not Known
Operon components: None
Similarity: In the C-terminal section; belongs to the PPC synthetase family [H]
Homologues:
Organism=Homo sapiens, GI71725351, Length=152, Percent_Identity=34.8684210526316, Blast_Score=87, Evalue=3e-17, Organism=Escherichia coli, GI87082301, Length=375, Percent_Identity=32, Blast_Score=169, Evalue=3e-43, Organism=Caenorhabditis elegans, GI17560194, Length=180, Percent_Identity=35, Blast_Score=89, Evalue=6e-18, Organism=Saccharomyces cerevisiae, GI6322762, Length=184, Percent_Identity=34.7826086956522, Blast_Score=102, Evalue=1e-22, Organism=Drosophila melanogaster, GI24657262, Length=148, Percent_Identity=30.4054054054054, Blast_Score=70, Evalue=3e-12,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR005252 - InterPro: IPR007085 - InterPro: IPR003382 [H]
Pfam domain/function: PF04127 DFP; PF02441 Flavoprotein [H]
EC number: =4.1.1.36; =6.3.2.5 [H]
Molecular weight: Translated: 46575; Mature: 46575
Theoretical pI: Translated: 8.80; Mature: 8.80
Prosite motif: NA
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
1.7 %Cys (Translated Protein) 1.2 %Met (Translated Protein) 2.9 %Cys+Met (Translated Protein) 1.7 %Cys (Mature Protein) 1.2 %Met (Mature Protein) 2.9 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MKTKSNDSKIKVLLLITGSIAAVRIPLLVSQLAKENYEIRCVLSKNAEKLIKPLSLSILS CCCCCCCCEEEEEEEEECCHHHHHHHHHHHHHHHCCCEEEEEECCCHHHHHHHHHHHEEC RNPCILEDDQWSNSQSTPLHIELSNWADILIIAPLTATTLAKWVTGNAEGLIPSILIANI CCCCEECCCCCCCCCCCEEEEEECCCCCEEEECCCHHHHHHHHHCCCCCCCHHHHHHHCC KPIIVAPAMNTQMWLNKAVQENYKNLKNYENVLSLQPSEGLLACDAIGIGKIPPNNLIQL CCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHEEECCCCCEEEEECCCCCCCCCHHHHHH ALEFIALHKQNEYRKDLLNKEILITGGCTSEKIDAARHITNRSSGAMGLLLSQVARFRGA HHHHHHHHCCCHHHHHHCCCEEEEECCCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHCCC QVKYVHGPLKIDKNLTDGIKRYEIETSVDLIRALDNEISNCDYFFMNAAVSDFKITSDTS EEEEEECCEEECCCHHHHHHHEEEHHHHHHHHHHHHHCCCCCEEEEECCCCCEEEECCCC AKIPKNKINEHLNQNFELVPDILKTISKSKKDNQVFVGFCAFTGSIEEARITIKEKIIQK CCCCHHHHHHHHCCCHHHHHHHHHHHHCCCCCCEEEEEEEEECCCHHHHHHHHHHHHHHH GCDFLFANPIDLEGQGFGFLAQNEGWLFDTNNLEHYIKKTSKIDLANKLITQIISLKK CCCEEECCCCCCCCCCCEEEECCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHHCCC >Mature Secondary Structure MKTKSNDSKIKVLLLITGSIAAVRIPLLVSQLAKENYEIRCVLSKNAEKLIKPLSLSILS CCCCCCCCEEEEEEEEECCHHHHHHHHHHHHHHHCCCEEEEEECCCHHHHHHHHHHHEEC RNPCILEDDQWSNSQSTPLHIELSNWADILIIAPLTATTLAKWVTGNAEGLIPSILIANI CCCCEECCCCCCCCCCCEEEEEECCCCCEEEECCCHHHHHHHHHCCCCCCCHHHHHHHCC KPIIVAPAMNTQMWLNKAVQENYKNLKNYENVLSLQPSEGLLACDAIGIGKIPPNNLIQL CCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHEEECCCCCEEEEECCCCCCCCCHHHHHH ALEFIALHKQNEYRKDLLNKEILITGGCTSEKIDAARHITNRSSGAMGLLLSQVARFRGA HHHHHHHHCCCHHHHHHCCCEEEEECCCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHCCC QVKYVHGPLKIDKNLTDGIKRYEIETSVDLIRALDNEISNCDYFFMNAAVSDFKITSDTS EEEEEECCEEECCCHHHHHHHEEEHHHHHHHHHHHHHCCCCCEEEEECCCCCEEEECCCC AKIPKNKINEHLNQNFELVPDILKTISKSKKDNQVFVGFCAFTGSIEEARITIKEKIIQK CCCCHHHHHHHHCCCHHHHHHHHHHHHCCCCCCEEEEEEEEECCCHHHHHHHHHHHHHHH GCDFLFANPIDLEGQGFGFLAQNEGWLFDTNNLEHYIKKTSKIDLANKLITQIISLKK CCCEEECCCCCCCCCCCEEEECCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHHCCC
PDB accession: NA
Resolution: NA
Structure class: Alpha Beta
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 9.0
TargetDB status: NA
Availability: NA
References: 8905231 [H]