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The map label for this gene is speA

Identifier: 126695386

GI number: 126695386

Start: 51859

End: 53805

Strand: Reverse

Name: speA

Synonym: P9301_00481

Alternate gene names: 126695386

Gene position: 53805-51859 (Counterclockwise)

Preceding gene: 126695388

Following gene: 126695384

Centisome position: 3.28

GC content: 29.33

Gene sequence:

>1947_bases
TTGACCAATTTTGAGCCGAAAAAACTAAAGAATGTTTGGACTATTGAAGATAGTATTTCGACTTATAACATAGACAAATG
GGGAGATAAATATTTTTCTATAAATTCCAAAGGCAATATATCAGTAACTAAAGATATAAAATCTGAAAATAAGATTGATC
TTTTTAAGCTTGTCAAAGAACTTAAGAGTAGAGAAATAAATCCTCCATTAATCATAAGATTTAATGATATCTTGAAAGAT
CGCATAAATGCACTACATGACTCTTTTTTTAAAGCGATCAAAACCTATAAATATAAGAACATTTATCAAGGCGTTTTTCC
TGTCAAATGTAATCAACAGAAAAATGTCCTAGAAAAGATAATAGATTTTGGTAGCCAATGGAATTTTGGTTTAGAAGTAG
GAAGTAAATCAGAACTATTAATTGGCCTTGCACTTCTTGAAAACCATAATTCATTATTAATATGCAACGGATATAAAGAT
AAAAAATATATTGAGATTGCTACTTTGGCCAGAAAACTCGGCAAAAATCCAATAATAGTTATTGAACAACGAGATGAGGT
AAAAAGAATTATTCAAGCAGTTCAAGAACTTAACGCGACTCCATTGATAGGAATTAGAGCAAAGTTATCAAGTAAAAGTA
GTGGTAGGTGGGGTAAATCTATTGGAGATAATTCCAAATTTGGATTATCAATCCCAGAAATTATGTTGACAATAAAAGAA
TTGAAAGAAGCAAATCTTATCAACGAAATGAAATTGCTCCATTTTCATATAGGCAGTCAAATAAGTGATATTGCTGTGAT
CAAAGACGCTTTACAAGAAGCGAGTCAAATATATGTTGAACTATGCAAACTAGGAGCCCCAATGCAATATATCGACGTTG
GAGGAGGATTAGGAATAGATTTTGATGGAACTAAAACCTCCTCCAACACCTCTACTAATTATTCTCTTCAAAATTATGCT
AACGATGTTATTGCAACTATTAAAGATTCATGTGAATTAAATAATATCAAGCATCCAACAATAATCTCAGAAAGTGGAAG
AGCAATCATTAGTCATTGTTCAGTATTAATTTTTAATGTCTTAGGAACAAGCCATGTTAGTTCCAAACTACAAATTTTTG
ATAAAAAAAATCAACAATTAATAATTTCAAATTTACTTGAAACTTACTATGAATTAAAAAAACTTAAAAATAAAAAAATA
AATTTATCTCAAATAATTGAACTATGGAATGATGCAAAAAAGTTTAAAGAAGATTGCTTAGTCGCTTTTAGATTAGGATT
TTTAAGTTTAGCAGAAAGAGCTTATGCCGAGGAACTTGCTTGGGCTTGCGCAAAAGAAATTTCTAATAACCTGAATAATG
ATGAAATCAATCACCCTGATTTATCTGAAATTACAGAAACTCTTGCATCAACTTATTATGCAAATTTATCTATCTTTAAA
TCTATTCCCGATAGCTGGGCAATAAATCAGATTTTTCCAATAGTACCAATACATAGGCACTTAGAAGAGCCTTTCTGCAA
AGGCAACTTTGCAGATTTAACTTGTGATTCAGATGGGAAACTAAATAATTTTATTGATGATGGAAAAATTAAATCATTAC
TAAATTTACATGAGCCAGAGAAAGATAAAGATTATCTAATTGGAATTTTTATGACTGGAGCTTATCAAGAAGCATTAGGA
AACTTGCACAATTTATTTGGCAGTACAAACGTTGTTCATATAGACATAAATCAAGATGATTCATATAAGGTCAAAAATAT
TATTAAAGAGGACAGTAAATCAGAAATTTTGCAATTATTAGATTACAGTTCAGCTTCTTTGGTTGAATCTATAAGAATTA
ATACTGAATCAGCAATTGATCAAAAAAAATTAACTATTGAAGAAGCAAGAAAATTAATGGATCAAATCGAAATTAGTCTC
AGAAAAAGTAGTTATTTATCAGAATGA

Upstream 100 bases:

>100_bases
ATATTCAACTTTTGGGTGGTAACTTGGCAAGTAATCATTAAAATAAGAGATATTGTTTTAAGTTATTTTCAAAAACATTT
ATTAATCACTAAGACATAAA

Downstream 100 bases:

>100_bases
CTATCTAATGTTTTTTGCAAATAATTTTTAGCATAATCTATAGCATCACTTAACTTATCAATATCTTTAGCTCCTGCTTG
AGCAAAGTTAGGCTTTCCTC

Product: arginine decarboxylase

Products: NA

Alternate protein names: ADC

Number of amino acids: Translated: 648; Mature: 647

Protein sequence:

>648_residues
MTNFEPKKLKNVWTIEDSISTYNIDKWGDKYFSINSKGNISVTKDIKSENKIDLFKLVKELKSREINPPLIIRFNDILKD
RINALHDSFFKAIKTYKYKNIYQGVFPVKCNQQKNVLEKIIDFGSQWNFGLEVGSKSELLIGLALLENHNSLLICNGYKD
KKYIEIATLARKLGKNPIIVIEQRDEVKRIIQAVQELNATPLIGIRAKLSSKSSGRWGKSIGDNSKFGLSIPEIMLTIKE
LKEANLINEMKLLHFHIGSQISDIAVIKDALQEASQIYVELCKLGAPMQYIDVGGGLGIDFDGTKTSSNTSTNYSLQNYA
NDVIATIKDSCELNNIKHPTIISESGRAIISHCSVLIFNVLGTSHVSSKLQIFDKKNQQLIISNLLETYYELKKLKNKKI
NLSQIIELWNDAKKFKEDCLVAFRLGFLSLAERAYAEELAWACAKEISNNLNNDEINHPDLSEITETLASTYYANLSIFK
SIPDSWAINQIFPIVPIHRHLEEPFCKGNFADLTCDSDGKLNNFIDDGKIKSLLNLHEPEKDKDYLIGIFMTGAYQEALG
NLHNLFGSTNVVHIDINQDDSYKVKNIIKEDSKSEILQLLDYSSASLVESIRINTESAIDQKKLTIEEARKLMDQIEISL
RKSSYLSE

Sequences:

>Translated_648_residues
MTNFEPKKLKNVWTIEDSISTYNIDKWGDKYFSINSKGNISVTKDIKSENKIDLFKLVKELKSREINPPLIIRFNDILKD
RINALHDSFFKAIKTYKYKNIYQGVFPVKCNQQKNVLEKIIDFGSQWNFGLEVGSKSELLIGLALLENHNSLLICNGYKD
KKYIEIATLARKLGKNPIIVIEQRDEVKRIIQAVQELNATPLIGIRAKLSSKSSGRWGKSIGDNSKFGLSIPEIMLTIKE
LKEANLINEMKLLHFHIGSQISDIAVIKDALQEASQIYVELCKLGAPMQYIDVGGGLGIDFDGTKTSSNTSTNYSLQNYA
NDVIATIKDSCELNNIKHPTIISESGRAIISHCSVLIFNVLGTSHVSSKLQIFDKKNQQLIISNLLETYYELKKLKNKKI
NLSQIIELWNDAKKFKEDCLVAFRLGFLSLAERAYAEELAWACAKEISNNLNNDEINHPDLSEITETLASTYYANLSIFK
SIPDSWAINQIFPIVPIHRHLEEPFCKGNFADLTCDSDGKLNNFIDDGKIKSLLNLHEPEKDKDYLIGIFMTGAYQEALG
NLHNLFGSTNVVHIDINQDDSYKVKNIIKEDSKSEILQLLDYSSASLVESIRINTESAIDQKKLTIEEARKLMDQIEISL
RKSSYLSE
>Mature_647_residues
TNFEPKKLKNVWTIEDSISTYNIDKWGDKYFSINSKGNISVTKDIKSENKIDLFKLVKELKSREINPPLIIRFNDILKDR
INALHDSFFKAIKTYKYKNIYQGVFPVKCNQQKNVLEKIIDFGSQWNFGLEVGSKSELLIGLALLENHNSLLICNGYKDK
KYIEIATLARKLGKNPIIVIEQRDEVKRIIQAVQELNATPLIGIRAKLSSKSSGRWGKSIGDNSKFGLSIPEIMLTIKEL
KEANLINEMKLLHFHIGSQISDIAVIKDALQEASQIYVELCKLGAPMQYIDVGGGLGIDFDGTKTSSNTSTNYSLQNYAN
DVIATIKDSCELNNIKHPTIISESGRAIISHCSVLIFNVLGTSHVSSKLQIFDKKNQQLIISNLLETYYELKKLKNKKIN
LSQIIELWNDAKKFKEDCLVAFRLGFLSLAERAYAEELAWACAKEISNNLNNDEINHPDLSEITETLASTYYANLSIFKS
IPDSWAINQIFPIVPIHRHLEEPFCKGNFADLTCDSDGKLNNFIDDGKIKSLLNLHEPEKDKDYLIGIFMTGAYQEALGN
LHNLFGSTNVVHIDINQDDSYKVKNIIKEDSKSEILQLLDYSSASLVESIRINTESAIDQKKLTIEEARKLMDQIEISLR
KSSYLSE

Specific function: Catalyzes the biosynthesis of agmatine from arginine

COG id: COG1166

COG function: function code E; Arginine decarboxylase (spermidine biosynthesis)

Gene ontology:

Cell location: Periplasmic Protein [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the Orn/Lys/Arg decarboxylase class-II family. SpeA subfamily

Homologues:

Organism=Escherichia coli, GI1789307, Length=632, Percent_Identity=34.9683544303797, Blast_Score=448, Evalue=1e-127,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): SPEA_PROM0 (A3PA96)

Other databases:

- EMBL:   CP000576
- RefSeq:   YP_001090272.1
- STRING:   A3PA96
- GeneID:   4912068
- GenomeReviews:   CP000576_GR
- KEGG:   pmg:P9301_00481
- eggNOG:   COG1166
- HOGENOM:   HBG321436
- OMA:   TCDSDGE
- ProtClustDB:   PRK05354
- BioCyc:   PMAR167546:P9301ORF_0049-MONOMER
- HAMAP:   MF_01417
- InterPro:   IPR009006
- InterPro:   IPR002985
- InterPro:   IPR022643
- InterPro:   IPR022657
- InterPro:   IPR022644
- InterPro:   IPR022653
- InterPro:   IPR000183
- Gene3D:   G3DSA:2.40.37.10
- PANTHER:   PTHR11482:SF3
- PIRSF:   PIRSF001336
- PRINTS:   PR01180
- PRINTS:   PR01179
- TIGRFAMs:   TIGR01273

Pfam domain/function: PF02784 Orn_Arg_deC_N; PF00278 Orn_DAP_Arg_deC; SSF50621 Racem_decarbox_C

EC number: =4.1.1.19

Molecular weight: Translated: 73367; Mature: 73236

Theoretical pI: Translated: 6.98; Mature: 6.98

Prosite motif: PS00878 ODR_DC_2_1; PS00879 ODR_DC_2_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTNFEPKKLKNVWTIEDSISTYNIDKWGDKYFSINSKGNISVTKDIKSENKIDLFKLVKE
CCCCCCHHHCCEEEEECCCCEECCCCCCCCEEEECCCCCEEEEECCCCCCCHHHHHHHHH
LKSREINPPLIIRFNDILKDRINALHDSFFKAIKTYKYKNIYQGVFPVKCNQQKNVLEKI
HHHCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEECCCHHHHHHHH
IDFGSQWNFGLEVGSKSELLIGLALLENHNSLLICNGYKDKKYIEIATLARKLGKNPIIV
HHCCCCCCCEEECCCCCCCEEEEEEEECCCCEEEEECCCCCHHHHHHHHHHHHCCCCEEE
IEQRDEVKRIIQAVQELNATPLIGIRAKLSSKSSGRWGKSIGDNSKFGLSIPEIMLTIKE
EECCHHHHHHHHHHHHCCCCCEEEEEEECCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHH
LKEANLINEMKLLHFHIGSQISDIAVIKDALQEASQIYVELCKLGAPMQYIDVGGGLGID
HHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCC
FDGTKTSSNTSTNYSLQNYANDVIATIKDSCELNNIKHPTIISESGRAIISHCSVLIFNV
CCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCEECCCCHHHHHHHHHHHHHH
LGTSHVSSKLQIFDKKNQQLIISNLLETYYELKKLKNKKINLSQIIELWNDAKKFKEDCL
HCCHHHHHHHHEECCCCCHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHH
VAFRLGFLSLAERAYAEELAWACAKEISNNLNNDEINHPDLSEITETLASTYYANLSIFK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHH
SIPDSWAINQIFPIVPIHRHLEEPFCKGNFADLTCDSDGKLNNFIDDGKIKSLLNLHEPE
HCCCCCCHHHHCCCCCHHHHHCCCCCCCCCCEEEECCCCCCCCCCCCHHHHHHHHCCCCC
KDKDYLIGIFMTGAYQEALGNLHNLFGSTNVVHIDINQDDSYKVKNIIKEDSKSEILQLL
CCCCEEEEEEECCHHHHHHHHHHHHHCCCCEEEEECCCCCCHHHHHHHHCCCHHHHHHHH
DYSSASLVESIRINTESAIDQKKLTIEEARKLMDQIEISLRKSSYLSE
CCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
TNFEPKKLKNVWTIEDSISTYNIDKWGDKYFSINSKGNISVTKDIKSENKIDLFKLVKE
CCCCCHHHCCEEEEECCCCEECCCCCCCCEEEECCCCCEEEEECCCCCCCHHHHHHHHH
LKSREINPPLIIRFNDILKDRINALHDSFFKAIKTYKYKNIYQGVFPVKCNQQKNVLEKI
HHHCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEECCCHHHHHHHH
IDFGSQWNFGLEVGSKSELLIGLALLENHNSLLICNGYKDKKYIEIATLARKLGKNPIIV
HHCCCCCCCEEECCCCCCCEEEEEEEECCCCEEEEECCCCCHHHHHHHHHHHHCCCCEEE
IEQRDEVKRIIQAVQELNATPLIGIRAKLSSKSSGRWGKSIGDNSKFGLSIPEIMLTIKE
EECCHHHHHHHHHHHHCCCCCEEEEEEECCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHH
LKEANLINEMKLLHFHIGSQISDIAVIKDALQEASQIYVELCKLGAPMQYIDVGGGLGID
HHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCC
FDGTKTSSNTSTNYSLQNYANDVIATIKDSCELNNIKHPTIISESGRAIISHCSVLIFNV
CCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCEECCCCHHHHHHHHHHHHHH
LGTSHVSSKLQIFDKKNQQLIISNLLETYYELKKLKNKKINLSQIIELWNDAKKFKEDCL
HCCHHHHHHHHEECCCCCHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHH
VAFRLGFLSLAERAYAEELAWACAKEISNNLNNDEINHPDLSEITETLASTYYANLSIFK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHH
SIPDSWAINQIFPIVPIHRHLEEPFCKGNFADLTCDSDGKLNNFIDDGKIKSLLNLHEPE
HCCCCCCHHHHCCCCCHHHHHCCCCCCCCCCEEEECCCCCCCCCCCCHHHHHHHHCCCCC
KDKDYLIGIFMTGAYQEALGNLHNLFGSTNVVHIDINQDDSYKVKNIIKEDSKSEILQLL
CCCCEEEEEEECCHHHHHHHHHHHHHCCCCEEEEECCCCCCHHHHHHHHCCCHHHHHHHH
DYSSASLVESIRINTESAIDQKKLTIEEARKLMDQIEISLRKSSYLSE
CCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA