| Definition | Prochlorococcus marinus str. MIT 9301, complete genome. |
|---|---|
| Accession | NC_009091 |
| Length | 1,641,879 |
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The map label for this gene is gyrA [H]
Identifier: 126695342
GI number: 126695342
Start: 5884
End: 8325
Strand: Reverse
Name: gyrA [H]
Synonym: P9301_00041
Alternate gene names: 126695342
Gene position: 8325-5884 (Counterclockwise)
Preceding gene: 126695343
Following gene: NA
Centisome position: 0.51
GC content: 27.35
Gene sequence:
>2442_bases ATGGATAAGAAAAACTTCACTTCTATCTCACTTCAAGAAGAAATGCAACGTTCTTATTTGGAGTATGCAATGAGCGTAAT AGTTGGACGTGCTCTACCCGATGCAAGAGACGGCCTTAAGCCTGTGCAAAGAAGAATACTATTTGCAATGTACGAGTTAG GTTTAACACCTGATAAGCCATTTAGAAAGTGTGCGAGAGTTGTAGGAGATGTACTTGGAAAGTACCATCCTCATGGAGAT CAGGCAGTATATGATGCATTAGTAAGGCTAGTACAAGATTTTTCTACAAAATATCCTACTCTTGACGGCCATGGAAATTT TGGATCTGTAGATAACGATCCGCCAGCAGCAATGAGATATACTGAAACCAGATTAGCTTCGATAGCTCATAAAGGTTTTC TTGAAGAAATTGGATCAGAAACAGTAAGTTTTTCGAATAACTTTGACGGTTCTCAAACAGAACCAGATGTTCTTCCGGCC CAACTTCCATTTTTATTGTTAAACGGCTCATCAGGTATTGCTGTCGGCATGGCAACAAACATACCCCCTCACAACCTAGG CGAAATTGTAGATAGCTTAGTTGCTTTAGTAAAAAATAATGATATTAGTAATAAAAAACTTTCTAAAATTATTCAAGGAC CTGATTTTCCTACTGGAGGAGAGCTAATTCATAGTGCAGCAATAGAAGAACTTTATGAAACAGGAAAAGGATCTTTAACA ATAAGAGGAGTTATAAATATGGAAGAAGTAAATTTAGGCAAAGGTAAACATAAAAAGAATGCGCTAATAATTACAGAACT TCCTTACCAAATTAGTAAAGCAGGTTGGATTGAAAAACTCGCAGAACTTGTCAATTCAGGTAAAATTCATGGAATCTCTG ATATTAGAGACGAAAGCGATAGAGATGGAATGAGAATTGTAATAGAGCTAAAAAAAGATTCTAATTCTGAACTTGTTATT TCTAATTTATATAAAAAAACAACTCTTCAAACAAACTTTGGTGCGATATTCTTAGCTTTAATTAAAGGCAAGCCTGTACA ATTAAGCCTAAAAAAATATCTCAACTTTTTTCTCGAATTTAGAGAAGAAACAATTAGAAAAAGAACTTTTTATTTTCTAA AAAACACTCTTGAAAAACTAGAAATATTAGAAGGTTTATCTAAAGCCACAAAAAACATAAAAAAAGTTGTAGCAATTATT GAAGAATCAGAAAATTCTGTAGAAGCTAAATCGAAATTAATTAAAAATTTTTTCCTAAGTGAAAAACAAGCAAGTTCAGT TTTAGATATGCCACTAAGAAAATTAACAAATCTAGAAAAGAATCAAATTGATAATGAAATAATAAATTTGGAAGAAAAAA AGAGTTATTTTCAAAAATTATTAAACGAAAGAGAATTATTACTCGAATTACTTATAGAAGAGCTATTAATCTTAAAGAAG AAATACAATGTTAAACGTAAAACAAAAGTAATTAAAAATATCAATCAAAATAAAGAACTAGAAAATCTCAATAATCAGAT ATTAGAGGAATTCATAAATAAAAAAACTAAATTATGCATTGACAATAGACTTTACTTAAAGAAAATGATTTTAGGTAATT ACAAGAAATCATTTGAAGTTGTAAATAAATTTATAGATAATAAAAATATTCAAAAATTTATATGCAATATTGAAAAAAAT ATAAAATTAATTGGCATCACAAATACAGGAAAAGTTTTTAATATTGATTGGGAGTCAAATGTAAATAATGACTATAAATT AGACAATAAAATACTTGGAAATATTCATCCTAGTGAAATAATAAACTTTCATTCAATTAAAAAAGAAATTAAAAATTATT TATGCATCTTGAATTCAGATGGAAGATTTAAAAAAGTATTATTTGATGAAGATATGATTAAAAGTAATAGATCTTTCACA ATTACAAAATTAAAAAATAATTTAAAAACAATTGATTCATTTATTTCTAATAAAAACAAAGATTTAATAATTTTAACCTC GATAGGAAGAATTTTTAGATTTAATTTATCAAATAAAATTTTAACGCCAACTTCTAAACAATCCCAAGGATTAATACTCG CAAAACTTTTACCAAGTGAAACAATCGTATCTTGTTGTCCATTTGATAATGGAGAAAATATTTTTTTAATATCTAGACAA GGAAAAATTTTTTGTATAAATAGTAATGAAATTTATTATTCCAATGAATACAGCTTGGGTTACTTAAATGAAAAAACCCA ACTTAAAAACGATTGCTTCTTTAAAATAGTAACAAGTAACCATTATCTTGATATTGAAACTAATAAAAATAAATCTGCAA GATTAGACCTAAATAAATTAAATTTCAAACCAAATAAATCAAAATTTTTAATAGATTTTTTAAACTTAGACAAAGATGAA TATCTTGAAAATTGTTTCCGACTTGAAAATTTTATCGACTAA
Upstream 100 bases:
>100_bases CCAAAATAACTGAATCATCTTAATTTTCAATACTGGTAAATATTGTTTTACCTATTAGTCTTAATTTAATTAATCAATAT TTTTTCAATTTTACGTTCTA
Downstream 100 bases:
>100_bases GATTTATATTCATTTTCAACCCAATTTAAGTATTCTTGATTTACTGTTCCGGTTACATAAGACCCGGTAAAGCAACTCAT CTCCAAATCCTGAATAGGAG
Product: DNA gyrase/topoisomerase IV, subunit A
Products: NA
Alternate protein names: NA
Number of amino acids: Translated: 813; Mature: 813
Protein sequence:
>813_residues MDKKNFTSISLQEEMQRSYLEYAMSVIVGRALPDARDGLKPVQRRILFAMYELGLTPDKPFRKCARVVGDVLGKYHPHGD QAVYDALVRLVQDFSTKYPTLDGHGNFGSVDNDPPAAMRYTETRLASIAHKGFLEEIGSETVSFSNNFDGSQTEPDVLPA QLPFLLLNGSSGIAVGMATNIPPHNLGEIVDSLVALVKNNDISNKKLSKIIQGPDFPTGGELIHSAAIEELYETGKGSLT IRGVINMEEVNLGKGKHKKNALIITELPYQISKAGWIEKLAELVNSGKIHGISDIRDESDRDGMRIVIELKKDSNSELVI SNLYKKTTLQTNFGAIFLALIKGKPVQLSLKKYLNFFLEFREETIRKRTFYFLKNTLEKLEILEGLSKATKNIKKVVAII EESENSVEAKSKLIKNFFLSEKQASSVLDMPLRKLTNLEKNQIDNEIINLEEKKSYFQKLLNERELLLELLIEELLILKK KYNVKRKTKVIKNINQNKELENLNNQILEEFINKKTKLCIDNRLYLKKMILGNYKKSFEVVNKFIDNKNIQKFICNIEKN IKLIGITNTGKVFNIDWESNVNNDYKLDNKILGNIHPSEIINFHSIKKEIKNYLCILNSDGRFKKVLFDEDMIKSNRSFT ITKLKNNLKTIDSFISNKNKDLIILTSIGRIFRFNLSNKILTPTSKQSQGLILAKLLPSETIVSCCPFDNGENIFLISRQ GKIFCINSNEIYYSNEYSLGYLNEKTQLKNDCFFKIVTSNHYLDIETNKNKSARLDLNKLNFKPNKSKFLIDFLNLDKDE YLENCFRLENFID
Sequences:
>Translated_813_residues MDKKNFTSISLQEEMQRSYLEYAMSVIVGRALPDARDGLKPVQRRILFAMYELGLTPDKPFRKCARVVGDVLGKYHPHGD QAVYDALVRLVQDFSTKYPTLDGHGNFGSVDNDPPAAMRYTETRLASIAHKGFLEEIGSETVSFSNNFDGSQTEPDVLPA QLPFLLLNGSSGIAVGMATNIPPHNLGEIVDSLVALVKNNDISNKKLSKIIQGPDFPTGGELIHSAAIEELYETGKGSLT IRGVINMEEVNLGKGKHKKNALIITELPYQISKAGWIEKLAELVNSGKIHGISDIRDESDRDGMRIVIELKKDSNSELVI SNLYKKTTLQTNFGAIFLALIKGKPVQLSLKKYLNFFLEFREETIRKRTFYFLKNTLEKLEILEGLSKATKNIKKVVAII EESENSVEAKSKLIKNFFLSEKQASSVLDMPLRKLTNLEKNQIDNEIINLEEKKSYFQKLLNERELLLELLIEELLILKK KYNVKRKTKVIKNINQNKELENLNNQILEEFINKKTKLCIDNRLYLKKMILGNYKKSFEVVNKFIDNKNIQKFICNIEKN IKLIGITNTGKVFNIDWESNVNNDYKLDNKILGNIHPSEIINFHSIKKEIKNYLCILNSDGRFKKVLFDEDMIKSNRSFT ITKLKNNLKTIDSFISNKNKDLIILTSIGRIFRFNLSNKILTPTSKQSQGLILAKLLPSETIVSCCPFDNGENIFLISRQ GKIFCINSNEIYYSNEYSLGYLNEKTQLKNDCFFKIVTSNHYLDIETNKNKSARLDLNKLNFKPNKSKFLIDFLNLDKDE YLENCFRLENFID >Mature_813_residues MDKKNFTSISLQEEMQRSYLEYAMSVIVGRALPDARDGLKPVQRRILFAMYELGLTPDKPFRKCARVVGDVLGKYHPHGD QAVYDALVRLVQDFSTKYPTLDGHGNFGSVDNDPPAAMRYTETRLASIAHKGFLEEIGSETVSFSNNFDGSQTEPDVLPA QLPFLLLNGSSGIAVGMATNIPPHNLGEIVDSLVALVKNNDISNKKLSKIIQGPDFPTGGELIHSAAIEELYETGKGSLT IRGVINMEEVNLGKGKHKKNALIITELPYQISKAGWIEKLAELVNSGKIHGISDIRDESDRDGMRIVIELKKDSNSELVI SNLYKKTTLQTNFGAIFLALIKGKPVQLSLKKYLNFFLEFREETIRKRTFYFLKNTLEKLEILEGLSKATKNIKKVVAII EESENSVEAKSKLIKNFFLSEKQASSVLDMPLRKLTNLEKNQIDNEIINLEEKKSYFQKLLNERELLLELLIEELLILKK KYNVKRKTKVIKNINQNKELENLNNQILEEFINKKTKLCIDNRLYLKKMILGNYKKSFEVVNKFIDNKNIQKFICNIEKN IKLIGITNTGKVFNIDWESNVNNDYKLDNKILGNIHPSEIINFHSIKKEIKNYLCILNSDGRFKKVLFDEDMIKSNRSFT ITKLKNNLKTIDSFISNKNKDLIILTSIGRIFRFNLSNKILTPTSKQSQGLILAKLLPSETIVSCCPFDNGENIFLISRQ GKIFCINSNEIYYSNEYSLGYLNEKTQLKNDCFFKIVTSNHYLDIETNKNKSARLDLNKLNFKPNKSKFLIDFLNLDKDE YLENCFRLENFID
Specific function: DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings [H]
COG id: COG0188
COG function: function code L; Type IIA topoisomerase (DNA gyrase/topo II, topoisomerase IV), A subunit
Gene ontology:
Cell location: Cytoplasm [C]
Metaboloic importance: Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Belongs to the topoisomerase gyrA/parC subunit family [H]
Homologues:
Organism=Homo sapiens, GI19913408, Length=351, Percent_Identity=25.9259259259259, Blast_Score=77, Evalue=9e-14, Organism=Homo sapiens, GI19913406, Length=174, Percent_Identity=31.6091954022989, Blast_Score=72, Evalue=3e-12, Organism=Escherichia coli, GI1788562, Length=730, Percent_Identity=36.8493150684931, Blast_Score=462, Evalue=1e-131, Organism=Escherichia coli, GI1789396, Length=707, Percent_Identity=34.2291371994342, Blast_Score=362, Evalue=1e-101, Organism=Caenorhabditis elegans, GI212645845, Length=347, Percent_Identity=27.9538904899135, Blast_Score=84, Evalue=3e-16, Organism=Caenorhabditis elegans, GI17535065, Length=180, Percent_Identity=30.5555555555556, Blast_Score=72, Evalue=8e-13, Organism=Saccharomyces cerevisiae, GI6324241, Length=291, Percent_Identity=27.1477663230241, Blast_Score=77, Evalue=1e-14,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR020899 - InterPro: IPR005743 - InterPro: IPR006691 - InterPro: IPR002205 - InterPro: IPR013758 - InterPro: IPR013757 - InterPro: IPR013760 [H]
Pfam domain/function: PF03989 DNA_gyraseA_C; PF00521 DNA_topoisoIV [H]
EC number: =5.99.1.3 [H]
Molecular weight: Translated: 92969; Mature: 92969
Theoretical pI: Translated: 9.49; Mature: 9.49
Prosite motif: NA
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
1.1 %Cys (Translated Protein) 1.4 %Met (Translated Protein) 2.5 %Cys+Met (Translated Protein) 1.1 %Cys (Mature Protein) 1.4 %Met (Mature Protein) 2.5 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MDKKNFTSISLQEEMQRSYLEYAMSVIVGRALPDARDGLKPVQRRILFAMYELGLTPDKP CCCCCCCEEEHHHHHHHHHHHHHHHHHHHHCCCCHHCCHHHHHHHHHHHHHHHCCCCCHH FRKCARVVGDVLGKYHPHGDQAVYDALVRLVQDFSTKYPTLDGHGNFGSVDNDPPAAMRY HHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCHHHH TETRLASIAHKGFLEEIGSETVSFSNNFDGSQTEPDVLPAQLPFLLLNGSSGIAVGMATN HHHHHHHHHHHHHHHHHCCCCEECCCCCCCCCCCCCCCCCCCCEEEEECCCCEEEEEECC IPPHNLGEIVDSLVALVKNNDISNKKLSKIIQGPDFPTGGELIHSAAIEELYETGKGSLT CCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHCCCCCEE IRGVINMEEVNLGKGKHKKNALIITELPYQISKAGWIEKLAELVNSGKIHGISDIRDESD EEEEEEHHHCCCCCCCCCCCEEEEEECCHHHHHHHHHHHHHHHHHCCCCCCCHHHCCCCC RDGMRIVIELKKDSNSELVISNLYKKTTLQTNFGAIFLALIKGKPVQLSLKKYLNFFLEF CCCCEEEEEEECCCCCCEEHHHHHHHHHCCCCHHHHEEHHHCCCCCEEHHHHHHHHHHHH REETIRKRTFYFLKNTLEKLEILEGLSKATKNIKKVVAIIEESENSVEAKSKLIKNFFLS HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHC EKQASSVLDMPLRKLTNLEKNQIDNEIINLEEKKSYFQKLLNERELLLELLIEELLILKK HHHHHHHHHHHHHHHCCCHHHHCCHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH KYNVKRKTKVIKNINQNKELENLNNQILEEFINKKTKLCIDNRLYLKKMILGNYKKSFEV HCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCHHHEEECCHHHHHHHHHCCHHHHHHH VNKFIDNKNIQKFICNIEKNIKLIGITNTGKVFNIDWESNVNNDYKLDNKILGNIHPSEI HHHHHCCCCHHHHHHHHCCCEEEEEEECCCEEEEEECCCCCCCCCEECCHHCCCCCHHHH INFHSIKKEIKNYLCILNSDGRFKKVLFDEDMIKSNRSFTITKLKNNLKTIDSFISNKNK HHHHHHHHHHHHEEEEECCCCCEEEEEECHHHHHCCCCEEEEHHHHHHHHHHHHHCCCCC DLIILTSIGRIFRFNLSNKILTPTSKQSQGLILAKLLPSETIVSCCPFDNGENIFLISRQ CEEEEECCCCEEEEECCCCEECCCCCCCCCEEEEECCCCCHHEEECCCCCCCEEEEEECC GKIFCINSNEIYYSNEYSLGYLNEKTQLKNDCFFKIVTSNHYLDIETNKNKSARLDLNKL CEEEEEECCEEEEECCCCEEECCCHHHCCCCCEEEEEECCEEEEEECCCCCCEEEEHHHC NFKPNKSKFLIDFLNLDKDEYLENCFRLENFID CCCCCCCEEEEEECCCCHHHHHHHHHHHHHHCC >Mature Secondary Structure MDKKNFTSISLQEEMQRSYLEYAMSVIVGRALPDARDGLKPVQRRILFAMYELGLTPDKP CCCCCCCEEEHHHHHHHHHHHHHHHHHHHHCCCCHHCCHHHHHHHHHHHHHHHCCCCCHH FRKCARVVGDVLGKYHPHGDQAVYDALVRLVQDFSTKYPTLDGHGNFGSVDNDPPAAMRY HHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCHHHH TETRLASIAHKGFLEEIGSETVSFSNNFDGSQTEPDVLPAQLPFLLLNGSSGIAVGMATN HHHHHHHHHHHHHHHHHCCCCEECCCCCCCCCCCCCCCCCCCCEEEEECCCCEEEEEECC IPPHNLGEIVDSLVALVKNNDISNKKLSKIIQGPDFPTGGELIHSAAIEELYETGKGSLT CCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHCCCCCEE IRGVINMEEVNLGKGKHKKNALIITELPYQISKAGWIEKLAELVNSGKIHGISDIRDESD EEEEEEHHHCCCCCCCCCCCEEEEEECCHHHHHHHHHHHHHHHHHCCCCCCCHHHCCCCC RDGMRIVIELKKDSNSELVISNLYKKTTLQTNFGAIFLALIKGKPVQLSLKKYLNFFLEF CCCCEEEEEEECCCCCCEEHHHHHHHHHCCCCHHHHEEHHHCCCCCEEHHHHHHHHHHHH REETIRKRTFYFLKNTLEKLEILEGLSKATKNIKKVVAIIEESENSVEAKSKLIKNFFLS HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHC EKQASSVLDMPLRKLTNLEKNQIDNEIINLEEKKSYFQKLLNERELLLELLIEELLILKK HHHHHHHHHHHHHHHCCCHHHHCCHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH KYNVKRKTKVIKNINQNKELENLNNQILEEFINKKTKLCIDNRLYLKKMILGNYKKSFEV HCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCHHHEEECCHHHHHHHHHCCHHHHHHH VNKFIDNKNIQKFICNIEKNIKLIGITNTGKVFNIDWESNVNNDYKLDNKILGNIHPSEI HHHHHCCCCHHHHHHHHCCCEEEEEEECCCEEEEEECCCCCCCCCEECCHHCCCCCHHHH INFHSIKKEIKNYLCILNSDGRFKKVLFDEDMIKSNRSFTITKLKNNLKTIDSFISNKNK HHHHHHHHHHHHEEEEECCCCCEEEEEECHHHHHCCCCEEEEHHHHHHHHHHHHHCCCCC DLIILTSIGRIFRFNLSNKILTPTSKQSQGLILAKLLPSETIVSCCPFDNGENIFLISRQ CEEEEECCCCEEEEECCCCEECCCCCCCCCEEEEECCCCCHHEEECCCCCCCEEEEEECC GKIFCINSNEIYYSNEYSLGYLNEKTQLKNDCFFKIVTSNHYLDIETNKNKSARLDLNKL CEEEEEECCEEEEECCCCEEECCCHHHCCCCCEEEEEECCEEEEEECCCCCCEEEEHHHC NFKPNKSKFLIDFLNLDKDEYLENCFRLENFID CCCCCCCEEEEEECCCCHHHHHHHHHHHHHHCC
PDB accession: NA
Resolution: NA
Structure class: Alpha Beta
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 9.0
TargetDB status: NA
Availability: NA
References: 8590279; 8905231 [H]