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The map label for this gene is ybeC [H]

Identifier: 126455377

GI number: 126455377

Start: 3522051

End: 3523652

Strand: Reverse

Name: ybeC [H]

Synonym: BURPS1106A_3619

Alternate gene names: 126455377

Gene position: 3523652-3522051 (Counterclockwise)

Preceding gene: 126453189

Following gene: 126452438

Centisome position: 88.35

GC content: 65.36

Gene sequence:

>1602_bases
GTGAAGAGTTCTATTCAACGGAACATCGGTCCGTTCGCCCTGATGCTGACCGGGCTCGGTTCGATCATCGGATCGGGCTG
GCTGTTCGGCGCATGGAAGGCCGCCAAGATCGCCGGGCCCGCCGCCATCTGCGCGTGGATCATCGGCGCTGTCGTGATTC
TCGCCATTGCGCTCACGTACGCCGAGCTCGGCGCGATGTTCCCCGAATCGGGCGGCATGGTCCGCTACGCGCGCTACTCG
CACGGTTCGCTCGTCGGCTTCATCAGCGCGTGGGCGAACTGGATCGCGATCGTCTCGGTGATTCCGATCGAGGCGGAGGC
GTCGATCCAGTACATGAGCACGTGGCCGTATGCATGGGCGCACGCGCTGTTCGTCAACGGCGAACTCACGACACCCGGGC
TGCTGCTGTCGGCCATCCTCGTCGTCATCTACTTCCTGCTCAATTACTGGGGCGTGAAGCTCTTCGCGCGCGCGAACACC
GCGATCACGATCTTCAAGTTCCTGATTCCCGGCCTCACGATCGCGGGCCTGCTGCTGTCGAGCTTCCATAGCGAGAACCT
CGGCACGGCGGGCGGCTCGTCGGGCTTCGCGCCGTACGGCTGGTCGGCCGTGCTGACGGCGGTTGCGACGAGCGGCATCG
TGTTCGCGTTCAACGGCTTCCAGAGCCCCGTGAACCTCGCCGGCGAGGCGCGCAATCCGTCGCGCAGCGTGCCGTTCGCG
GTGATCTCGTCGATCCTGATCGCGCTCGTGATCTACGTGCTGCTGCAAGTAGCGTACATCGGCGCGGTGAACCCGGCCGA
CGTCGCGAAGGGCTGGGCGCACTTCAACTTCGCGTCGCCGTTCGCGGAGCTCGCGATCGCGCTGAACCTGAACTGGCTCG
CGATCCTGCTGTACGTCGACGCGTTCGTGAGCCCGAGCGGCACCGGCACGACCTACATGGCGACGACGACCCGCATGATC
TACGCGATGGAGCGCAACAACACGATGCCGAAGATCTTCGGCAGCGTGCACCCGCTGTACGGCGTGCCGCGTCCCGCGAT
GTGGTTCAACCTGATGGTGTCGTTCGTCTTCCTGTTCTTCTTCCGCGGCTGGAGCTCGCTCGCGGCGGTGATCTCGGTGG
CGACCGTGATCTCCTACCTGACGGGCCCGATCAGCCTGATGGCGCTGCGCCGCGCGGCGACCGACCTCGAGCGTCCGCTG
GCGATTCCGTGCATGAAGCTGATCGCGCCGTTCGCGTTCGTCTGCGCGTCGCTGATCCTGTACTGGGCGAAGTGGCCGCT
GACGGGCGAGATCATCCTGCTGATGATCGTCGCGCTGCCCGTGTATTTCTACTACCAGGGCAAGGCCGGCTGGAGCGGCT
GGGGCCGCGACCTGAAAGCCGCTTGGTGGCTCGTCGCGTACCTGCCGACGATGGCCGTGCTGTCGCTCATCGGCAGCAAG
GAGTTCGGCGGTCACGGCGTGCTGCCGTACGGGTGGGACATGCTGGTCGTCGCGGCGATCGCGCTCGTGTTCTACTACTG
GGGCGTGCACACCGGCTATCGCACCGAATATCTCGACGAACGCGAATCGCGCGACGAGATCCTCGAAGGGATCGGCGCGT
AA

Upstream 100 bases:

>100_bases
CCCGATCGGGCAACCCGTCCTCCAAGAATGCATGCGCGGTATCGTCCGGCTCGATCCCGGGCGGTATGCCGACCGTGCTT
GTTGAGACATAGGAGAGGTT

Downstream 100 bases:

>100_bases
TCGCACGCTCCGTCGCCGGCGATCGGCGGCGACGGGGGCCGAGCCCTTCGAATGAAGCCCGCCCGGGATGTCCCGGGCGG
GCTTTGTCGTTTTGGGGCCG

Product: amino acid permease

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 533; Mature: 533

Protein sequence:

>533_residues
MKSSIQRNIGPFALMLTGLGSIIGSGWLFGAWKAAKIAGPAAICAWIIGAVVILAIALTYAELGAMFPESGGMVRYARYS
HGSLVGFISAWANWIAIVSVIPIEAEASIQYMSTWPYAWAHALFVNGELTTPGLLLSAILVVIYFLLNYWGVKLFARANT
AITIFKFLIPGLTIAGLLLSSFHSENLGTAGGSSGFAPYGWSAVLTAVATSGIVFAFNGFQSPVNLAGEARNPSRSVPFA
VISSILIALVIYVLLQVAYIGAVNPADVAKGWAHFNFASPFAELAIALNLNWLAILLYVDAFVSPSGTGTTYMATTTRMI
YAMERNNTMPKIFGSVHPLYGVPRPAMWFNLMVSFVFLFFFRGWSSLAAVISVATVISYLTGPISLMALRRAATDLERPL
AIPCMKLIAPFAFVCASLILYWAKWPLTGEIILLMIVALPVYFYYQGKAGWSGWGRDLKAAWWLVAYLPTMAVLSLIGSK
EFGGHGVLPYGWDMLVVAAIALVFYYWGVHTGYRTEYLDERESRDEILEGIGA

Sequences:

>Translated_533_residues
MKSSIQRNIGPFALMLTGLGSIIGSGWLFGAWKAAKIAGPAAICAWIIGAVVILAIALTYAELGAMFPESGGMVRYARYS
HGSLVGFISAWANWIAIVSVIPIEAEASIQYMSTWPYAWAHALFVNGELTTPGLLLSAILVVIYFLLNYWGVKLFARANT
AITIFKFLIPGLTIAGLLLSSFHSENLGTAGGSSGFAPYGWSAVLTAVATSGIVFAFNGFQSPVNLAGEARNPSRSVPFA
VISSILIALVIYVLLQVAYIGAVNPADVAKGWAHFNFASPFAELAIALNLNWLAILLYVDAFVSPSGTGTTYMATTTRMI
YAMERNNTMPKIFGSVHPLYGVPRPAMWFNLMVSFVFLFFFRGWSSLAAVISVATVISYLTGPISLMALRRAATDLERPL
AIPCMKLIAPFAFVCASLILYWAKWPLTGEIILLMIVALPVYFYYQGKAGWSGWGRDLKAAWWLVAYLPTMAVLSLIGSK
EFGGHGVLPYGWDMLVVAAIALVFYYWGVHTGYRTEYLDERESRDEILEGIGA
>Mature_533_residues
MKSSIQRNIGPFALMLTGLGSIIGSGWLFGAWKAAKIAGPAAICAWIIGAVVILAIALTYAELGAMFPESGGMVRYARYS
HGSLVGFISAWANWIAIVSVIPIEAEASIQYMSTWPYAWAHALFVNGELTTPGLLLSAILVVIYFLLNYWGVKLFARANT
AITIFKFLIPGLTIAGLLLSSFHSENLGTAGGSSGFAPYGWSAVLTAVATSGIVFAFNGFQSPVNLAGEARNPSRSVPFA
VISSILIALVIYVLLQVAYIGAVNPADVAKGWAHFNFASPFAELAIALNLNWLAILLYVDAFVSPSGTGTTYMATTTRMI
YAMERNNTMPKIFGSVHPLYGVPRPAMWFNLMVSFVFLFFFRGWSSLAAVISVATVISYLTGPISLMALRRAATDLERPL
AIPCMKLIAPFAFVCASLILYWAKWPLTGEIILLMIVALPVYFYYQGKAGWSGWGRDLKAAWWLVAYLPTMAVLSLIGSK
EFGGHGVLPYGWDMLVVAAIALVFYYWGVHTGYRTEYLDERESRDEILEGIGA

Specific function: Uptake of an yet unknown amino-acid with the concomitant import of a proton [H]

COG id: COG0531

COG function: function code E; Amino acid transporters

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the amino acid-polyamine-organocation (APC) superfamily. AGT (TC 2.A.3.11) family [H]

Homologues:

Organism=Homo sapiens, GI4507047, Length=428, Percent_Identity=24.0654205607477, Blast_Score=83, Evalue=7e-16,
Organism=Homo sapiens, GI33286428, Length=459, Percent_Identity=24.400871459695, Blast_Score=76, Evalue=7e-14,
Organism=Homo sapiens, GI181337167, Length=260, Percent_Identity=29.2307692307692, Blast_Score=74, Evalue=5e-13,
Organism=Homo sapiens, GI110347453, Length=356, Percent_Identity=25, Blast_Score=73, Evalue=8e-13,
Organism=Homo sapiens, GI115648063, Length=349, Percent_Identity=24.9283667621776, Blast_Score=72, Evalue=1e-12,
Organism=Homo sapiens, GI115648022, Length=349, Percent_Identity=24.9283667621776, Blast_Score=72, Evalue=1e-12,
Organism=Homo sapiens, GI187423910, Length=405, Percent_Identity=24.1975308641975, Blast_Score=71, Evalue=2e-12,
Organism=Homo sapiens, GI7657591, Length=405, Percent_Identity=24.1975308641975, Blast_Score=71, Evalue=2e-12,
Organism=Homo sapiens, GI7657683, Length=414, Percent_Identity=23.9130434782609, Blast_Score=68, Evalue=2e-11,
Organism=Homo sapiens, GI258614005, Length=452, Percent_Identity=22.3451327433628, Blast_Score=66, Evalue=7e-11,
Organism=Homo sapiens, GI258614003, Length=452, Percent_Identity=22.3451327433628, Blast_Score=66, Evalue=1e-10,
Organism=Escherichia coli, GI87082250, Length=480, Percent_Identity=24.375, Blast_Score=94, Evalue=2e-20,
Organism=Escherichia coli, GI1786789, Length=453, Percent_Identity=24.2825607064018, Blast_Score=78, Evalue=2e-15,
Organism=Escherichia coli, GI1786302, Length=404, Percent_Identity=24.009900990099, Blast_Score=75, Evalue=1e-14,
Organism=Escherichia coli, GI1790653, Length=369, Percent_Identity=22.7642276422764, Blast_Score=71, Evalue=2e-13,
Organism=Escherichia coli, GI1786602, Length=368, Percent_Identity=24.7282608695652, Blast_Score=70, Evalue=4e-13,
Organism=Escherichia coli, GI1788480, Length=358, Percent_Identity=24.8603351955307, Blast_Score=70, Evalue=4e-13,
Organism=Escherichia coli, GI2367353, Length=281, Percent_Identity=29.1814946619217, Blast_Score=68, Evalue=1e-12,
Organism=Escherichia coli, GI1789017, Length=329, Percent_Identity=23.7082066869301, Blast_Score=68, Evalue=2e-12,
Organism=Escherichia coli, GI1787890, Length=380, Percent_Identity=25.5263157894737, Blast_Score=65, Evalue=9e-12,
Organism=Escherichia coli, GI87081869, Length=300, Percent_Identity=22.3333333333333, Blast_Score=64, Evalue=3e-11,
Organism=Escherichia coli, GI87081708, Length=393, Percent_Identity=24.4274809160305, Blast_Score=63, Evalue=4e-11,
Organism=Caenorhabditis elegans, GI17540018, Length=443, Percent_Identity=25.2821670428894, Blast_Score=85, Evalue=9e-17,
Organism=Caenorhabditis elegans, GI32566699, Length=360, Percent_Identity=26.6666666666667, Blast_Score=83, Evalue=3e-16,
Organism=Caenorhabditis elegans, GI17531343, Length=420, Percent_Identity=23.8095238095238, Blast_Score=79, Evalue=4e-15,
Organism=Caenorhabditis elegans, GI17532491, Length=415, Percent_Identity=24.3373493975904, Blast_Score=79, Evalue=5e-15,
Organism=Caenorhabditis elegans, GI17533459, Length=437, Percent_Identity=24.4851258581236, Blast_Score=75, Evalue=7e-14,
Organism=Drosophila melanogaster, GI24667468, Length=415, Percent_Identity=25.5421686746988, Blast_Score=104, Evalue=2e-22,
Organism=Drosophila melanogaster, GI21357367, Length=457, Percent_Identity=25.382932166302, Blast_Score=83, Evalue=4e-16,
Organism=Drosophila melanogaster, GI221512776, Length=416, Percent_Identity=23.3173076923077, Blast_Score=83, Evalue=5e-16,
Organism=Drosophila melanogaster, GI24666159, Length=416, Percent_Identity=23.3173076923077, Blast_Score=82, Evalue=6e-16,
Organism=Drosophila melanogaster, GI24651635, Length=448, Percent_Identity=25.4464285714286, Blast_Score=80, Evalue=3e-15,
Organism=Drosophila melanogaster, GI24651633, Length=448, Percent_Identity=25.4464285714286, Blast_Score=80, Evalue=3e-15,
Organism=Drosophila melanogaster, GI45550968, Length=422, Percent_Identity=24.6445497630332, Blast_Score=68, Evalue=1e-11,
Organism=Drosophila melanogaster, GI19921172, Length=422, Percent_Identity=24.6445497630332, Blast_Score=68, Evalue=1e-11,
Organism=Drosophila melanogaster, GI221331183, Length=469, Percent_Identity=22.8144989339019, Blast_Score=66, Evalue=6e-11,
Organism=Drosophila melanogaster, GI17647653, Length=469, Percent_Identity=22.8144989339019, Blast_Score=66, Evalue=6e-11,
Organism=Drosophila melanogaster, GI24664379, Length=469, Percent_Identity=22.8144989339019, Blast_Score=66, Evalue=6e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004841
- InterPro:   IPR002293 [H]

Pfam domain/function: PF00324 AA_permease [H]

EC number: NA

Molecular weight: Translated: 57865; Mature: 57865

Theoretical pI: Translated: 9.00; Mature: 9.00

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKSSIQRNIGPFALMLTGLGSIIGSGWLFGAWKAAKIAGPAAICAWIIGAVVILAIALTY
CCCCHHHCCCHHHHHHHHHHHHHHCCCHHHCCHHHHHCCHHHHHHHHHHHHHHHHHHHHH
AELGAMFPESGGMVRYARYSHGSLVGFISAWANWIAIVSVIPIEAEASIQYMSTWPYAWA
HHHHHCCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHCCCCCCCCEEHHHCCCHHHH
HALFVNGELTTPGLLLSAILVVIYFLLNYWGVKLFARANTAITIFKFLIPGLTIAGLLLS
HHEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHEECCHHHHHHHHHHHHHHHHHHHHH
SFHSENLGTAGGSSGFAPYGWSAVLTAVATSGIVFAFNGFQSPVNLAGEARNPSRSVPFA
HHHCCCCCCCCCCCCCCCCCHHHHHHHHHHCCEEEEECCCCCCHHHCCCCCCCCCCCCHH
VISSILIALVIYVLLQVAYIGAVNPADVAKGWAHFNFASPFAELAIALNLNWLAILLYVD
HHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCHHHHHHHHHCHHHHHHHHHHH
AFVSPSGTGTTYMATTTRMIYAMERNNTMPKIFGSVHPLYGVPRPAMWFNLMVSFVFLFF
HHCCCCCCCCEEEEEHHHHEEEECCCCCCHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHH
FRGWSSLAAVISVATVISYLTGPISLMALRRAATDLERPLAIPCMKLIAPFAFVCASLIL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHH
YWAKWPLTGEIILLMIVALPVYFYYQGKAGWSGWGRDLKAAWWLVAYLPTMAVLSLIGSK
HHHCCCCCHHHHHHHHHHHHHHHEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCC
EFGGHGVLPYGWDMLVVAAIALVFYYWGVHTGYRTEYLDERESRDEILEGIGA
CCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHCCHHHHHHHCCC
>Mature Secondary Structure
MKSSIQRNIGPFALMLTGLGSIIGSGWLFGAWKAAKIAGPAAICAWIIGAVVILAIALTY
CCCCHHHCCCHHHHHHHHHHHHHHCCCHHHCCHHHHHCCHHHHHHHHHHHHHHHHHHHHH
AELGAMFPESGGMVRYARYSHGSLVGFISAWANWIAIVSVIPIEAEASIQYMSTWPYAWA
HHHHHCCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHCCCCCCCCEEHHHCCCHHHH
HALFVNGELTTPGLLLSAILVVIYFLLNYWGVKLFARANTAITIFKFLIPGLTIAGLLLS
HHEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHEECCHHHHHHHHHHHHHHHHHHHHH
SFHSENLGTAGGSSGFAPYGWSAVLTAVATSGIVFAFNGFQSPVNLAGEARNPSRSVPFA
HHHCCCCCCCCCCCCCCCCCHHHHHHHHHHCCEEEEECCCCCCHHHCCCCCCCCCCCCHH
VISSILIALVIYVLLQVAYIGAVNPADVAKGWAHFNFASPFAELAIALNLNWLAILLYVD
HHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCHHHHHHHHHCHHHHHHHHHHH
AFVSPSGTGTTYMATTTRMIYAMERNNTMPKIFGSVHPLYGVPRPAMWFNLMVSFVFLFF
HHCCCCCCCCEEEEEHHHHEEEECCCCCCHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHH
FRGWSSLAAVISVATVISYLTGPISLMALRRAATDLERPLAIPCMKLIAPFAFVCASLIL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHH
YWAKWPLTGEIILLMIVALPVYFYYQGKAGWSGWGRDLKAAWWLVAYLPTMAVLSLIGSK
HHHCCCCCHHHHHHHHHHHHHHHEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCC
EFGGHGVLPYGWDMLVVAAIALVFYYWGVHTGYRTEYLDERESRDEILEGIGA
CCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHCCHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9384377; 12730183 [H]