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The map label for this gene is pyrC [H]

Identifier: 126455362

GI number: 126455362

Start: 3333545

End: 3334603

Strand: Reverse

Name: pyrC [H]

Synonym: BURPS1106A_3417

Alternate gene names: 126455362

Gene position: 3334603-3333545 (Counterclockwise)

Preceding gene: 126455447

Following gene: 126454421

Centisome position: 83.61

GC content: 69.78

Gene sequence:

>1059_bases
ATGAATGCTTCCGTTCCCGCCTCGCTGACCCTCGCCCGCCCCGACGACTGGCACCTGCACGTGCGCGACGGCGCGATGCT
CGCGGCCGTCCTGCCGCACACCGCCCGCCAGTTCGGCCGCGCGATCATCATGCCGAACCTGAAGCCGCCCGTCACGACGA
CCGCGCAGGCGCAGGCCTACCGCGAGCGCATCCTGGCCGCGGTGCCGGCCGGCATGACGTTCGAGCCGTTGATGACGCTG
TACCTGACCGACAACACGCCCGCCGACGAAATCCGCCGCGCACGCGAAAGCGGCTGCGTGCACGGCGTGAAGCTCTATCC
GGCGGGCGCGACGACGAACTCGGACGCCGGCGTGACCGACCTGCTCGGCAAGTGCGCGAAGACGCTCGAGGCGATGCAGG
AAGTCGGGATGCCGCTGCTCGTGCACGGCGAGGTGACGGATCCGTCGATCGACCTGTTCGACCGCGAGAAGGTGTTCATC
GATCGCGTGATGGAGCCGCTGCGCCGCGCGCTGCCGGGGCTCAAGGTGGTGTTCGAGCATATTACGACGAAGGATGCGGC
CGACTACGTGCGCGATGCCGACGCGGCGTCAGGCCGGATCGGCGCGACGATCACCGCGCACCATCTGCTGTACAACCGCA
ATGCGATGTTTTTCGGCGGCATCCGTCCACATTACTACTGCCTGCCGGTGCTCAAGCGCGAGACGCATCGGATCGCGCTC
GTCGAGGCGGCGACGTCGGGCAATCCGCGCTTCTTCCTCGGCACCGACAGCGCGCCGCACGCGAAAGGCGCGAAGGAAGC
CGCGTGCGGCTGCGCGGGCTGCTACACCGCGCTGCACGCGCTCGAGCTGTACGCGGAGGCATTCGACCAGGCGGGCGCGC
TCGACAAGCTCGAAGGCTTCGCGAGCTTCTTCGGCGCGGACTTCTACGGTTTGCCGCGCAGCGCCGAGACGGTGACGCTG
CGCCGCGAGACGTGGGAGCTGCCGCGCGAGATCGACGCGGGCGCCGGCCCGGTCGTGCCGCTGCGCGGCGGCGAGGCGAT
CGGCTGGCGGCTCGTCTGA

Upstream 100 bases:

>100_bases
GCGAGCGGTTCCGTGTTGCGGTTTGCCGTCAGTCGGGCGGCGCCGCGCGCGGCCGGCGCGCCGCGCATCGCGCCTCGCCG
CGCGCCATTCCCACGACACC

Downstream 100 bases:

>100_bases
TGCTCGCGGCGCCGCGGCGGGCCGGGTTGCCGCGCGCGGCGGCTTCGGTGTCGACATGATGAGCGGGGCGCACGCCATGA
GCGCTCGGAGTGCCGGGAAG

Product: dihydroorotase

Products: NA

Alternate protein names: DHOase [H]

Number of amino acids: Translated: 352; Mature: 352

Protein sequence:

>352_residues
MNASVPASLTLARPDDWHLHVRDGAMLAAVLPHTARQFGRAIIMPNLKPPVTTTAQAQAYRERILAAVPAGMTFEPLMTL
YLTDNTPADEIRRARESGCVHGVKLYPAGATTNSDAGVTDLLGKCAKTLEAMQEVGMPLLVHGEVTDPSIDLFDREKVFI
DRVMEPLRRALPGLKVVFEHITTKDAADYVRDADAASGRIGATITAHHLLYNRNAMFFGGIRPHYYCLPVLKRETHRIAL
VEAATSGNPRFFLGTDSAPHAKGAKEAACGCAGCYTALHALELYAEAFDQAGALDKLEGFASFFGADFYGLPRSAETVTL
RRETWELPREIDAGAGPVVPLRGGEAIGWRLV

Sequences:

>Translated_352_residues
MNASVPASLTLARPDDWHLHVRDGAMLAAVLPHTARQFGRAIIMPNLKPPVTTTAQAQAYRERILAAVPAGMTFEPLMTL
YLTDNTPADEIRRARESGCVHGVKLYPAGATTNSDAGVTDLLGKCAKTLEAMQEVGMPLLVHGEVTDPSIDLFDREKVFI
DRVMEPLRRALPGLKVVFEHITTKDAADYVRDADAASGRIGATITAHHLLYNRNAMFFGGIRPHYYCLPVLKRETHRIAL
VEAATSGNPRFFLGTDSAPHAKGAKEAACGCAGCYTALHALELYAEAFDQAGALDKLEGFASFFGADFYGLPRSAETVTL
RRETWELPREIDAGAGPVVPLRGGEAIGWRLV
>Mature_352_residues
MNASVPASLTLARPDDWHLHVRDGAMLAAVLPHTARQFGRAIIMPNLKPPVTTTAQAQAYRERILAAVPAGMTFEPLMTL
YLTDNTPADEIRRARESGCVHGVKLYPAGATTNSDAGVTDLLGKCAKTLEAMQEVGMPLLVHGEVTDPSIDLFDREKVFI
DRVMEPLRRALPGLKVVFEHITTKDAADYVRDADAASGRIGATITAHHLLYNRNAMFFGGIRPHYYCLPVLKRETHRIAL
VEAATSGNPRFFLGTDSAPHAKGAKEAACGCAGCYTALHALELYAEAFDQAGALDKLEGFASFFGADFYGLPRSAETVTL
RRETWELPREIDAGAGPVVPLRGGEAIGWRLV

Specific function: Pyrimidine biosynthesis; third step. [C]

COG id: COG0418

COG function: function code F; Dihydroorotase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the DHOase family. Type 1 subfamily [H]

Homologues:

Organism=Escherichia coli, GI1787301, Length=343, Percent_Identity=55.1020408163265, Blast_Score=379, Evalue=1e-106,
Organism=Saccharomyces cerevisiae, GI6323452, Length=357, Percent_Identity=35.5742296918768, Blast_Score=190, Evalue=3e-49,

Paralogues:

None

Copy number: 340 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006680
- InterPro:   IPR004721
- InterPro:   IPR002195 [H]

Pfam domain/function: PF01979 Amidohydro_1 [H]

EC number: =3.5.2.3 [H]

Molecular weight: Translated: 38178; Mature: 38178

Theoretical pI: Translated: 6.79; Mature: 6.79

Prosite motif: PS00482 DIHYDROOROTASE_1 ; PS00483 DIHYDROOROTASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNASVPASLTLARPDDWHLHVRDGAMLAAVLPHTARQFGRAIIMPNLKPPVTTTAQAQAY
CCCCCCCEEEEECCCCCEEEEECCCCHHHHHHHHHHHHCCEEECCCCCCCCCCCHHHHHH
RERILAAVPAGMTFEPLMTLYLTDNTPADEIRRARESGCVHGVKLYPAGATTNSDAGVTD
HHHHHHHCCCCCCHHCEEEEEEECCCCHHHHHHHHHCCCEECEEEEECCCCCCCCCCHHH
LLGKCAKTLEAMQEVGMPLLVHGEVTDPSIDLFDREKVFIDRVMEPLRRALPGLKVVFEH
HHHHHHHHHHHHHHCCCCEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHCCHHHHHHHH
ITTKDAADYVRDADAASGRIGATITAHHLLYNRNAMFFGGIRPHYYCLPVLKRETHRIAL
HHCHHHHHHHHCCCCCCCCCCCEEEEEHHEEECCEEEECCCCCCEEEEHHHHCCCCEEEE
VEAATSGNPRFFLGTDSAPHAKGAKEAACGCAGCYTALHALELYAEAFDQAGALDKLEGF
EEEECCCCCEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHH
ASFFGADFYGLPRSAETVTLRRETWELPREIDAGAGPVVPLRGGEAIGWRLV
HHHHCCCCCCCCCCCCEEEEEHHHHCCCHHHCCCCCCEEECCCCCCCCCEEC
>Mature Secondary Structure
MNASVPASLTLARPDDWHLHVRDGAMLAAVLPHTARQFGRAIIMPNLKPPVTTTAQAQAY
CCCCCCCEEEEECCCCCEEEEECCCCHHHHHHHHHHHHCCEEECCCCCCCCCCCHHHHHH
RERILAAVPAGMTFEPLMTLYLTDNTPADEIRRARESGCVHGVKLYPAGATTNSDAGVTD
HHHHHHHCCCCCCHHCEEEEEEECCCCHHHHHHHHHCCCEECEEEEECCCCCCCCCCHHH
LLGKCAKTLEAMQEVGMPLLVHGEVTDPSIDLFDREKVFIDRVMEPLRRALPGLKVVFEH
HHHHHHHHHHHHHHCCCCEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHCCHHHHHHHH
ITTKDAADYVRDADAASGRIGATITAHHLLYNRNAMFFGGIRPHYYCLPVLKRETHRIAL
HHCHHHHHHHHCCCCCCCCCCCEEEEEHHEEECCEEEECCCCCCEEEEHHHHCCCCEEEE
VEAATSGNPRFFLGTDSAPHAKGAKEAACGCAGCYTALHALELYAEAFDQAGALDKLEGF
EEEECCCCCEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHH
ASFFGADFYGLPRSAETVTLRRETWELPREIDAGAGPVVPLRGGEAIGWRLV
HHHHCCCCCCCCCCCCEEEEEHHHHCCCHHHCCCCCCEEECCCCCCCCCEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA