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The map label for this gene is panE

Identifier: 126455328

GI number: 126455328

Start: 2342163

End: 2343164

Strand: Reverse

Name: panE

Synonym: BURPS1106A_2371

Alternate gene names: NA

Gene position: 2343164-2342163 (Counterclockwise)

Preceding gene: 126451894

Following gene: 126451467

Centisome position: 58.75

GC content: 74.05

Gene sequence:

>1002_bases
ATGGATCGAGCACCGGTGCGCGCGGCGATCGTCGGGATCGGCGCGATCGGCGGGCTGTTTGCGGCGGGGCTCGCGCGCGC
GGGCTGGGACGTGAGCGCGCTTGCGCGCGGCGCGACGCTCGATGCGCTGCGCGGGCGCGGGCTGCGAATCGTCGGCGAGT
CGGGCGGCGAGTCGGGCGGCGAAACGGCGGTCGCGCTGCGCGCGAGCGACGACGCGCACGCGCTCGGCGAACAGGATTAT
GTCGTCGTCGCGTTGAAGGCGCACGCGCTGCCGGCGCTTGCTTCGCGCATCGCGCCGCTCGTCGGGCCGCGCACGATCAT
CGTCGCCGCGATGAACGGCCTGCCGTGGTGGTTTTTCGACGGCTTCGGCGGCCCGCTCGACGGCGCGGCGCTCGACGCGG
TCGATCCGGGCGGCGTGACGGCTGCCGCGCTGCCGCCCGCGCGCGCGATCGGCTGCGTGGTGCACCTGTCGTCGGCGACG
CGCGAACCGGGCGTCGTCGTGCGCGGCCGCGGCAACCGGCTGATCGTCGGCGCGCCGCGCGCCGCGCTGCGCGAGCCGGG
CGAGCGCGTTGCCGACGCGCTCGCGGCGGGCGGCTTCGACGTCGAGCGTTCGGCCGACATCCGCACCGACATCTGGGCGA
AGCTCTGGGGCAACATGAACATGAATCCGCTCAGCGCGCTGACGGGATCGGCGGCGGACCGCCTGCTCGACGATCCGCAT
ACGAACGCGCTCGCGCTGCGGATGATGGAGGAGGCCGACGCGATCGGCGCGCGGCTCGGCTTGTCGGCGGGGATGAGCGG
CGCCGAGCGGATCGCGGTGACGCGCCAGTTGGGCGCGTTCAGGACGTCGATGCTGCAGGACCTGGAGGCCGGGCGTGCGC
TCGAGATCGGGCCGATTCTGGGCGTGTTTCCGGAACTTGGGCGCCGGCTGGGCGTGCCGACGCCGTATTGCGACGCGGTG
CTCGGATTGTTGCGCCAGCGCGCGTTCAATGCCGGGCTGTGA

Upstream 100 bases:

>100_bases
GCGACATCGACGGCTGACGCGCGGTGCGCGCGGCCGGATGGTTGTGCATGCAACTATTTGGCTCTATGCTCGCGGCTTCA
TCGAACGAGGAGAAACGCAT

Downstream 100 bases:

>100_bases
GGCGTCGCGCGGCGGCTGGAGCCGGCCGCCGCGAGCGGCGCGTCGGCGATGCGGCAAGGTATGGGGCCGCGCAGGCGCGG
CGGAACCGGGATTGGGTTGG

Product: 2-dehydropantoate 2-reductase

Products: NA

Alternate protein names: Ketopantoate reductase; KPA reductase; KPR [H]

Number of amino acids: Translated: 333; Mature: 333

Protein sequence:

>333_residues
MDRAPVRAAIVGIGAIGGLFAAGLARAGWDVSALARGATLDALRGRGLRIVGESGGESGGETAVALRASDDAHALGEQDY
VVVALKAHALPALASRIAPLVGPRTIIVAAMNGLPWWFFDGFGGPLDGAALDAVDPGGVTAAALPPARAIGCVVHLSSAT
REPGVVVRGRGNRLIVGAPRAALREPGERVADALAAGGFDVERSADIRTDIWAKLWGNMNMNPLSALTGSAADRLLDDPH
TNALALRMMEEADAIGARLGLSAGMSGAERIAVTRQLGAFRTSMLQDLEAGRALEIGPILGVFPELGRRLGVPTPYCDAV
LGLLRQRAFNAGL

Sequences:

>Translated_333_residues
MDRAPVRAAIVGIGAIGGLFAAGLARAGWDVSALARGATLDALRGRGLRIVGESGGESGGETAVALRASDDAHALGEQDY
VVVALKAHALPALASRIAPLVGPRTIIVAAMNGLPWWFFDGFGGPLDGAALDAVDPGGVTAAALPPARAIGCVVHLSSAT
REPGVVVRGRGNRLIVGAPRAALREPGERVADALAAGGFDVERSADIRTDIWAKLWGNMNMNPLSALTGSAADRLLDDPH
TNALALRMMEEADAIGARLGLSAGMSGAERIAVTRQLGAFRTSMLQDLEAGRALEIGPILGVFPELGRRLGVPTPYCDAV
LGLLRQRAFNAGL
>Mature_333_residues
MDRAPVRAAIVGIGAIGGLFAAGLARAGWDVSALARGATLDALRGRGLRIVGESGGESGGETAVALRASDDAHALGEQDY
VVVALKAHALPALASRIAPLVGPRTIIVAAMNGLPWWFFDGFGGPLDGAALDAVDPGGVTAAALPPARAIGCVVHLSSAT
REPGVVVRGRGNRLIVGAPRAALREPGERVADALAAGGFDVERSADIRTDIWAKLWGNMNMNPLSALTGSAADRLLDDPH
TNALALRMMEEADAIGARLGLSAGMSGAERIAVTRQLGAFRTSMLQDLEAGRALEIGPILGVFPELGRRLGVPTPYCDAV
LGLLRQRAFNAGL

Specific function: Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid [H]

COG id: COG1893

COG function: function code H; Ketopantoate reductase

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ketopantoate reductase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008927
- InterPro:   IPR003710
- InterPro:   IPR013752
- InterPro:   IPR013332
- InterPro:   IPR013328
- InterPro:   IPR016040 [H]

Pfam domain/function: PF02558 ApbA; PF08546 ApbA_C [H]

EC number: =1.1.1.169 [H]

Molecular weight: Translated: 34204; Mature: 34204

Theoretical pI: Translated: 6.96; Mature: 6.96

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDRAPVRAAIVGIGAIGGLFAAGLARAGWDVSALARGATLDALRGRGLRIVGESGGESGG
CCCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHCCCHHHHHCCCCEEEEECCCCCCCC
ETAVALRASDDAHALGEQDYVVVALKAHALPALASRIAPLVGPRTIIVAAMNGLPWWFFD
CEEEEEEECCCHHHCCCCCEEEEEEEHHHHHHHHHHHHHHCCCCEEEEEECCCCCEEEEC
GFGGPLDGAALDAVDPGGVTAAALPPARAIGCVVHLSSATREPGVVVRGRGNRLIVGAPR
CCCCCCCCCEECCCCCCCEEEECCCCHHHHHHEEEECCCCCCCCEEEECCCCEEEEECCH
AALREPGERVADALAAGGFDVERSADIRTDIWAKLWGNMNMNPLSALTGSAADRLLDDPH
HHHHCCHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCC
TNALALRMMEEADAIGARLGLSAGMSGAERIAVTRQLGAFRTSMLQDLEAGRALEIGPIL
CCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCEEEECHHH
GVFPELGRRLGVPTPYCDAVLGLLRQRAFNAGL
HHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MDRAPVRAAIVGIGAIGGLFAAGLARAGWDVSALARGATLDALRGRGLRIVGESGGESGG
CCCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHCCCHHHHHCCCCEEEEECCCCCCCC
ETAVALRASDDAHALGEQDYVVVALKAHALPALASRIAPLVGPRTIIVAAMNGLPWWFFD
CEEEEEEECCCHHHCCCCCEEEEEEEHHHHHHHHHHHHHHCCCCEEEEEECCCCCEEEEC
GFGGPLDGAALDAVDPGGVTAAALPPARAIGCVVHLSSATREPGVVVRGRGNRLIVGAPR
CCCCCCCCCEECCCCCCCEEEECCCCHHHHHHEEEECCCCCCCCEEEECCCCEEEEECCH
AALREPGERVADALAAGGFDVERSADIRTDIWAKLWGNMNMNPLSALTGSAADRLLDDPH
HHHHCCHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCC
TNALALRMMEEADAIGARLGLSAGMSGAERIAVTRQLGAFRTSMLQDLEAGRALEIGPIL
CCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCEEEECHHH
GVFPELGRRLGVPTPYCDAVLGLLRQRAFNAGL
HHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11214968 [H]