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The map label for this gene is 126455286

Identifier: 126455286

GI number: 126455286

Start: 772493

End: 774184

Strand: Direct

Name: 126455286

Synonym: BURPS1106A_0788

Alternate gene names: NA

Gene position: 772493-774184 (Clockwise)

Preceding gene: 126451683

Following gene: 126454514

Centisome position: 19.37

GC content: 71.1

Gene sequence:

>1692_bases
ATGCCGATTGACGATCCGCACGCGGCGTTCGCGCGCGCGCGCGGCGCCGACGGCCGCGCGCCCGACGTGATGCGCGTCGG
CGGCTGGGTGCCGATGCGCATGCACCGCGACGAGGACGAGGTGGATTTCGCGATCGTCGGCACGGGCGCGGGCGGCGGCA
CGCTCGCGTGCAAGCTCGCCGAATACGGCTACTCGGTCGTCGCGCTCGACGCGGGCGCGTGGTGGCGGCCGCTCGAGGAG
TTCGCCTCCGACGAGACGCATCAGCGCAAGCTGTACTGGACCGACGAGCGCCTGTGCGACGGCGACGATCCGCTCACGCT
CGGCAACAACAACAGCGGCAAGGCTGTGGGCGGCAGCACCGTGCATTTCGCGATGGTGTCGCTGCGCTTTCGCCCCGACT
GGTTCAAGTCGCGCACGCGGCTCGGCTACGGCGCGGACTGGCCGCTCGACTGGCGCGAGATGTGGCGCTATTACGCCGAG
GTGGAGGACGCGCTGAAGATCAGCGGGCCCGTTCGCTATCCGTGGGGGCCGAAGCGGCCGCGCTATCCGTATCGCGCGCA
CGAGCTGAACGCGGCCGCACTCGTGCTCGCGCGCGGCGCCGACGCGCTCGGCATCGGCTGGGCGCCGACGCCGCTCGCGA
CGCTGTCCGCGCCGCGCGGGCTCGCGCATCCGTGCGTGTACCGCGGCTTCTGCATCAGCGGCTGCGCGACGAACGCGAAA
CAGAGCGCGCTCGTCACGTGGATTCCGCGCGCGCTCGCGGCGGGCGCCGAGATCCGCGATCTCGCGATGGCGCTCGGCAT
CGAAACCGGCGCGAGCGGCGATCGCGTGACGGGCGTGCGCTACGTGCGCGAAGGCCGCGTGCGCTTTCAGCGCGCGAAGC
ACGTCGTCGTCGCAGGCTATGCGATCGAGACGCCGCGCCTCTTGCTGCTGTCGGCGAACGGCCGCCATCCGCACGGCCTC
GCGAACAGCGGCTCGGGCCTCGTCGGCAAGAACCTGATGGTGCAGCTCAATCAGGCCGCGTGGGGCACGATGCGCGATGA
AGTGCGCTGGTACAAGGGGCCGCCGTCGCTCGCGATCACCGAGCACTGGAACTACATGGACGCCGGCAAGGACTTCTTCG
GCGGCTACTGCTACATGAGCCAGGGGCCGCTTCCCGTCGAATGGGCGCGCAAGGTGGCGGGGCGCGGGCTGTGGGGCGAC
GCGCTCGTGCGCGAGATGGCGCGCTACAACCATCAGGCGGGCCTGAAGATGGTCGGCGAGACGCTGCCGCAGGCGCGCAA
CCGCGTGACGCTCGCCGACGAGAAGGACCCGTACGGACTGCCGATCGCGCGCGTCACCTATTCGTATTGCGACAACGACC
GGCGCATGATCGGGCATGCGCTCGCGTACATGTCGCTCGCGCTCGAGGCGGCGGGCGCGCACGACGTCTGGCAGGAGCAC
GACGACACCTGCCATCTCGGCGGCACCGCGCGGATGGGCGACGATCCGGCGACGAGCGTCGTCGATGCCGATTGCCGAAG
CTGGGACATTCCGAATCTGTGGATTTGCGACGGCTCGGTGTTTCCGACCGTCGGCGGCGTGAATCCGTCGCTGACGATCC
AGGCGATCGCGTGCCGCACCGCCGATCGCATCCGCGCGCTCGACGCGCGCGGCGAGCTGCGGCAGCGGGCGCGCCGCGGC
GGCGCAGGCTGA

Upstream 100 bases:

>100_bases
GCGCCGCTCGCGGCGCGCGACGACGGCCGTGCCGATGCCGACGCCGACGCCGCTTCGCCGCGCCGCCTCGCGCAACCGGG
AAAGCGCAAGGGGAACCGCG

Downstream 100 bases:

>100_bases
CGCCGCCGCGGTGCGCGACGCGCGGCCCGGCGCGCGGGCGGCGGCGCTACACGAGCTGCGCGATCGCGCCGCGCGGCGCG
CACCGATGCAGCTCGCGGCC

Product: GMC oxidoreductase

Products: NA

Alternate protein names: GA 2-DH dehydrogenase subunit; GADH dehydrogenase subunit [H]

Number of amino acids: Translated: 563; Mature: 562

Protein sequence:

>563_residues
MPIDDPHAAFARARGADGRAPDVMRVGGWVPMRMHRDEDEVDFAIVGTGAGGGTLACKLAEYGYSVVALDAGAWWRPLEE
FASDETHQRKLYWTDERLCDGDDPLTLGNNNSGKAVGGSTVHFAMVSLRFRPDWFKSRTRLGYGADWPLDWREMWRYYAE
VEDALKISGPVRYPWGPKRPRYPYRAHELNAAALVLARGADALGIGWAPTPLATLSAPRGLAHPCVYRGFCISGCATNAK
QSALVTWIPRALAAGAEIRDLAMALGIETGASGDRVTGVRYVREGRVRFQRAKHVVVAGYAIETPRLLLLSANGRHPHGL
ANSGSGLVGKNLMVQLNQAAWGTMRDEVRWYKGPPSLAITEHWNYMDAGKDFFGGYCYMSQGPLPVEWARKVAGRGLWGD
ALVREMARYNHQAGLKMVGETLPQARNRVTLADEKDPYGLPIARVTYSYCDNDRRMIGHALAYMSLALEAAGAHDVWQEH
DDTCHLGGTARMGDDPATSVVDADCRSWDIPNLWICDGSVFPTVGGVNPSLTIQAIACRTADRIRALDARGELRQRARRG
GAG

Sequences:

>Translated_563_residues
MPIDDPHAAFARARGADGRAPDVMRVGGWVPMRMHRDEDEVDFAIVGTGAGGGTLACKLAEYGYSVVALDAGAWWRPLEE
FASDETHQRKLYWTDERLCDGDDPLTLGNNNSGKAVGGSTVHFAMVSLRFRPDWFKSRTRLGYGADWPLDWREMWRYYAE
VEDALKISGPVRYPWGPKRPRYPYRAHELNAAALVLARGADALGIGWAPTPLATLSAPRGLAHPCVYRGFCISGCATNAK
QSALVTWIPRALAAGAEIRDLAMALGIETGASGDRVTGVRYVREGRVRFQRAKHVVVAGYAIETPRLLLLSANGRHPHGL
ANSGSGLVGKNLMVQLNQAAWGTMRDEVRWYKGPPSLAITEHWNYMDAGKDFFGGYCYMSQGPLPVEWARKVAGRGLWGD
ALVREMARYNHQAGLKMVGETLPQARNRVTLADEKDPYGLPIARVTYSYCDNDRRMIGHALAYMSLALEAAGAHDVWQEH
DDTCHLGGTARMGDDPATSVVDADCRSWDIPNLWICDGSVFPTVGGVNPSLTIQAIACRTADRIRALDARGELRQRARRG
GAG
>Mature_562_residues
PIDDPHAAFARARGADGRAPDVMRVGGWVPMRMHRDEDEVDFAIVGTGAGGGTLACKLAEYGYSVVALDAGAWWRPLEEF
ASDETHQRKLYWTDERLCDGDDPLTLGNNNSGKAVGGSTVHFAMVSLRFRPDWFKSRTRLGYGADWPLDWREMWRYYAEV
EDALKISGPVRYPWGPKRPRYPYRAHELNAAALVLARGADALGIGWAPTPLATLSAPRGLAHPCVYRGFCISGCATNAKQ
SALVTWIPRALAAGAEIRDLAMALGIETGASGDRVTGVRYVREGRVRFQRAKHVVVAGYAIETPRLLLLSANGRHPHGLA
NSGSGLVGKNLMVQLNQAAWGTMRDEVRWYKGPPSLAITEHWNYMDAGKDFFGGYCYMSQGPLPVEWARKVAGRGLWGDA
LVREMARYNHQAGLKMVGETLPQARNRVTLADEKDPYGLPIARVTYSYCDNDRRMIGHALAYMSLALEAAGAHDVWQEHD
DTCHLGGTARMGDDPATSVVDADCRSWDIPNLWICDGSVFPTVGGVNPSLTIQAIACRTADRIRALDARGELRQRARRGG
AG

Specific function: Part of the heterotrimer that catalyzes the conversion of D-gluconate to 2-dehydro-D-gluconate. This subunit functions as the dehydrogenase [H]

COG id: COG2303

COG function: function code E; Choline dehydrogenase and related flavoproteins

Gene ontology:

Cell location: Cell membrane; Peripheral membrane protein; Periplasmic side (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GMC oxidoreductase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000172
- InterPro:   IPR007867 [H]

Pfam domain/function: PF05199 GMC_oxred_C; PF00732 GMC_oxred_N [H]

EC number: =1.1.99.3 [H]

Molecular weight: Translated: 61764; Mature: 61632

Theoretical pI: Translated: 8.21; Mature: 8.21

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPIDDPHAAFARARGADGRAPDVMRVGGWVPMRMHRDEDEVDFAIVGTGAGGGTLACKLA
CCCCCHHHHHHHHCCCCCCCCCEEEECCEEEEEECCCCCCCEEEEEECCCCCCEEEEEEH
EYGYSVVALDAGAWWRPLEEFASDETHQRKLYWTDERLCDGDDPLTLGNNNSGKAVGGST
HCCCEEEEECCCCCHHHHHHHCCCCCCCCEEEECCCCCCCCCCCEEECCCCCCCCCCCCE
VHFAMVSLRFRPDWFKSRTRLGYGADWPLDWREMWRYYAEVEDALKISGPVRYPWGPKRP
EEEEEEEEEECCHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCEECCCCCCCC
RYPYRAHELNAAALVLARGADALGIGWAPTPLATLSAPRGLAHPCVYRGFCISGCATNAK
CCCCCHHHCCCEEEEEECCCCEEECCCCCCCHHHCCCCCCCCCCHHHHCEEHHCCCCCCC
QSALVTWIPRALAAGAEIRDLAMALGIETGASGDRVTGVRYVREGRVRFQRAKHVVVAGY
CCHHHHHHHHHHHCCCHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHCCEEEEEEE
AIETPRLLLLSANGRHPHGLANSGSGLVGKNLMVQLNQAAWGTMRDEVRWYKGPPSLAIT
EECCCEEEEEECCCCCCCCCCCCCCCCCCCCEEEEECCHHCCCHHHCCEEECCCCCEEEE
EHWNYMDAGKDFFGGYCYMSQGPLPVEWARKVAGRGLWGDALVREMARYNHQAGLKMVGE
ECCCCHHCCCCCCCCEEEECCCCCCHHHHHHHHCCCCCHHHHHHHHHHHCHHCCHHHHHH
TLPQARNRVTLADEKDPYGLPIARVTYSYCDNDRRMIGHALAYMSLALEAAGAHDVWQEH
HHHHHCCEEEEECCCCCCCCCHHHEEHHHHCCCHHHHHHHHHHHHHHHHHCCCHHHHHCC
DDTCHLGGTARMGDDPATSVVDADCRSWDIPNLWICDGSVFPTVGGVNPSLTIQAIACRT
CCEEECCCCCCCCCCCCCCEEECCCCCCCCCEEEEECCCCCCCCCCCCCCEEEEEEECCC
ADRIRALDARGELRQRARRGGAG
HHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
PIDDPHAAFARARGADGRAPDVMRVGGWVPMRMHRDEDEVDFAIVGTGAGGGTLACKLA
CCCCHHHHHHHHCCCCCCCCCEEEECCEEEEEECCCCCCCEEEEEECCCCCCEEEEEEH
EYGYSVVALDAGAWWRPLEEFASDETHQRKLYWTDERLCDGDDPLTLGNNNSGKAVGGST
HCCCEEEEECCCCCHHHHHHHCCCCCCCCEEEECCCCCCCCCCCEEECCCCCCCCCCCCE
VHFAMVSLRFRPDWFKSRTRLGYGADWPLDWREMWRYYAEVEDALKISGPVRYPWGPKRP
EEEEEEEEEECCHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCEECCCCCCCC
RYPYRAHELNAAALVLARGADALGIGWAPTPLATLSAPRGLAHPCVYRGFCISGCATNAK
CCCCCHHHCCCEEEEEECCCCEEECCCCCCCHHHCCCCCCCCCCHHHHCEEHHCCCCCCC
QSALVTWIPRALAAGAEIRDLAMALGIETGASGDRVTGVRYVREGRVRFQRAKHVVVAGY
CCHHHHHHHHHHHCCCHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHCCEEEEEEE
AIETPRLLLLSANGRHPHGLANSGSGLVGKNLMVQLNQAAWGTMRDEVRWYKGPPSLAIT
EECCCEEEEEECCCCCCCCCCCCCCCCCCCCEEEEECCHHCCCHHHCCEEECCCCCEEEE
EHWNYMDAGKDFFGGYCYMSQGPLPVEWARKVAGRGLWGDALVREMARYNHQAGLKMVGE
ECCCCHHCCCCCCCCEEEECCCCCCHHHHHHHHCCCCCHHHHHHHHHHHCHHCCHHHHHH
TLPQARNRVTLADEKDPYGLPIARVTYSYCDNDRRMIGHALAYMSLALEAAGAHDVWQEH
HHHHHCCEEEEECCCCCCCCCHHHEEHHHHCCCHHHHHHHHHHHHHHHHHCCCHHHHHCC
DDTCHLGGTARMGDDPATSVVDADCRSWDIPNLWICDGSVFPTVGGVNPSLTIQAIACRT
CCEEECCCCCCCCCCCCCCEEECCCCCCCCCEEEEECCCCCCCCCCCCCCEEEEEEECCC
ADRIRALDARGELRQRARRGGAG
HHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9352901 [H]