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The map label for this gene is queA [H]

Identifier: 126455279

GI number: 126455279

Start: 3280836

End: 3281918

Strand: Direct

Name: queA [H]

Synonym: BURPS1106A_3360

Alternate gene names: 126455279

Gene position: 3280836-3281918 (Clockwise)

Preceding gene: 126454838

Following gene: 126454794

Centisome position: 82.26

GC content: 71.75

Gene sequence:

>1083_bases
ATGCTCACGCTTTCCGATTTCGATTTCGATCTGCCGCCCGAGTTGATCGCGCAAACCGCGCTGCCCGAACGCAGCGCGAG
CCGCCTGCTCGAGGTGGACAACACGAACCCGAGCGCGCCCCCGCGCCTCGTCGACCGGCGCTTCGCCGAGCTGCCCGCGT
GCGTCGCGCCGGGCGACCTGCTCGTCTTCAACGACACGAAGGTGCTCAAGGCGCGCTTCTTCGGTCGCAAGGCAAGCGGC
GGCAAGATCGAGGTGCTGATCGAGCGCGTCACCGGCGAGCGCACCGCGCTCGCGCAGATCCGCGCGAGCAAGAGTCCTCC
GCCCGGCACCACGCTCACGCTCGCCGATGCGTTCGACGTGACGGTCGGCGAGCGCGTCGAGCCGTTCTTCACGCTGCACT
TCCCCGACGACTGCCTCGTGCTGATCGAGCGCCACGGCCGGCTGCCGCTGCCGCCGTACATCGAGCACGCGCCCGACGCG
GCCGACGAGACCCGCTATCAGACGGTGTTCGCCGCGAACCCGGGCGCCGTCGCCGCGCCGACGGCCGGCCTGCACTTCGA
CGACGCGGTGCTCGCCGCGCTCGAGGCGCGCGGCGTCGAGCGCGCGACGCTCACGCTGCACGTCGGCGCGGGCACGTTCC
AGCCGGTGCGCGTCGAAAACCTCGCCGAGCACCGGATGCACAGCGAGTCGTACGAGCTGACCGACGCGCTCGTCGAGAAG
ATCGCCGCGACCCGCGCACGCGGCGGCCGCGTGATCGCGGTCGGCACGACGTCGATGCGCGCGCTCGAGGCGGCCGCGCG
CGACGCGCAGGCGGCCGGCCGGCCGCTCGCCGCGACGCGCGCGGAAACCGACATCTTCATCACGCCGGGCTACCGTTTCC
GCGTGGTCGACCGGCTCGTGACGAATTTCCACTTGCCGAAATCGACGCTGCTGATGCTCGTGTCCGCGTTCGCCGGCATC
GAGACGATCCGCGCCGCGTACCGGCACGCGATCGACGCGCGCTACCGGTTCTTCAGCTACGGCGACGCGATGCTGCTCAC
GCGGCGCGACGACGCGGCCGAGGCGACGCACGGCGGCGCATAA

Upstream 100 bases:

>100_bases
GAGCGACGCCGGCCAAGCCGCGCAACCCCGCCATCATAGCGGCTCATGCGCGCCGCGACGCGCTTTGTCCATCTGGCCGG
CCGCCCCGACCCCGTTTCGC

Downstream 100 bases:

>100_bases
GCGCGGCGATTCGCGCCGATTGGCCCATCGGCCGAACAGCCGATCAGCCGATCGTTCGATTGGCTGTTCGGCTGTTCGGC
TGTTCGGCGGCTCGGCGGCT

Product: S-adenosylmethionine:tRNA ribosyltransferase-isomerase

Products: NA

Alternate protein names: Queuosine biosynthesis protein queA [H]

Number of amino acids: Translated: 360; Mature: 360

Protein sequence:

>360_residues
MLTLSDFDFDLPPELIAQTALPERSASRLLEVDNTNPSAPPRLVDRRFAELPACVAPGDLLVFNDTKVLKARFFGRKASG
GKIEVLIERVTGERTALAQIRASKSPPPGTTLTLADAFDVTVGERVEPFFTLHFPDDCLVLIERHGRLPLPPYIEHAPDA
ADETRYQTVFAANPGAVAAPTAGLHFDDAVLAALEARGVERATLTLHVGAGTFQPVRVENLAEHRMHSESYELTDALVEK
IAATRARGGRVIAVGTTSMRALEAAARDAQAAGRPLAATRAETDIFITPGYRFRVVDRLVTNFHLPKSTLLMLVSAFAGI
ETIRAAYRHAIDARYRFFSYGDAMLLTRRDDAAEATHGGA

Sequences:

>Translated_360_residues
MLTLSDFDFDLPPELIAQTALPERSASRLLEVDNTNPSAPPRLVDRRFAELPACVAPGDLLVFNDTKVLKARFFGRKASG
GKIEVLIERVTGERTALAQIRASKSPPPGTTLTLADAFDVTVGERVEPFFTLHFPDDCLVLIERHGRLPLPPYIEHAPDA
ADETRYQTVFAANPGAVAAPTAGLHFDDAVLAALEARGVERATLTLHVGAGTFQPVRVENLAEHRMHSESYELTDALVEK
IAATRARGGRVIAVGTTSMRALEAAARDAQAAGRPLAATRAETDIFITPGYRFRVVDRLVTNFHLPKSTLLMLVSAFAGI
ETIRAAYRHAIDARYRFFSYGDAMLLTRRDDAAEATHGGA
>Mature_360_residues
MLTLSDFDFDLPPELIAQTALPERSASRLLEVDNTNPSAPPRLVDRRFAELPACVAPGDLLVFNDTKVLKARFFGRKASG
GKIEVLIERVTGERTALAQIRASKSPPPGTTLTLADAFDVTVGERVEPFFTLHFPDDCLVLIERHGRLPLPPYIEHAPDA
ADETRYQTVFAANPGAVAAPTAGLHFDDAVLAALEARGVERATLTLHVGAGTFQPVRVENLAEHRMHSESYELTDALVEK
IAATRARGGRVIAVGTTSMRALEAAARDAQAAGRPLAATRAETDIFITPGYRFRVVDRLVTNFHLPKSTLLMLVSAFAGI
ETIRAAYRHAIDARYRFFSYGDAMLLTRRDDAAEATHGGA

Specific function: Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) [H]

COG id: COG0809

COG function: function code J; S-adenosylmethionine:tRNA-ribosyltransferase-isomerase (queuine synthetase)

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the queA family [H]

Homologues:

Organism=Escherichia coli, GI1786606, Length=351, Percent_Identity=52.4216524216524, Blast_Score=342, Evalue=2e-95,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003699 [H]

Pfam domain/function: PF02547 Queuosine_synth [H]

EC number: 5.-.-.- [C]

Molecular weight: Translated: 39123; Mature: 39123

Theoretical pI: Translated: 6.52; Mature: 6.52

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLTLSDFDFDLPPELIAQTALPERSASRLLEVDNTNPSAPPRLVDRRFAELPACVAPGDL
CCCCCCCCCCCCHHHHHHHCCCCHHHHHEEEECCCCCCCCHHHHHHHHHHCCCCCCCCCE
LVFNDTKVLKARFFGRKASGGKIEVLIERVTGERTALAQIRASKSPPPGTTLTLADAFDV
EEECCCHHHHHHHCCCCCCCCEEEEEEEECCCCHHHHHHHHCCCCCCCCCEEEEECCCCC
TVGERVEPFFTLHFPDDCLVLIERHGRLPLPPYIEHAPDAADETRYQTVFAANPGAVAAP
CCCCCCCCEEEEECCCCEEEEEECCCCCCCCCHHCCCCCCCCCCCEEEEEECCCCCCCCC
TAGLHFDDAVLAALEARGVERATLTLHVGAGTFQPVRVENLAEHRMHSESYELTDALVEK
CCCCCCHHHHHHHHHHCCCEEEEEEEEECCCCCCCCHHHHHHHHHHCCCHHHHHHHHHHH
IAATRARGGRVIAVGTTSMRALEAAARDAQAAGRPLAATRAETDIFITPGYRFRVVDRLV
HHHHHCCCCEEEEEECCHHHHHHHHHHHHHHCCCCCEECCCCCEEEECCCCHHHHHHHHH
TNFHLPKSTLLMLVSAFAGIETIRAAYRHAIDARYRFFSYGDAMLLTRRDDAAEATHGGA
HHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEECCCEEEEEECCCHHCCCCCCC
>Mature Secondary Structure
MLTLSDFDFDLPPELIAQTALPERSASRLLEVDNTNPSAPPRLVDRRFAELPACVAPGDL
CCCCCCCCCCCCHHHHHHHCCCCHHHHHEEEECCCCCCCCHHHHHHHHHHCCCCCCCCCE
LVFNDTKVLKARFFGRKASGGKIEVLIERVTGERTALAQIRASKSPPPGTTLTLADAFDV
EEECCCHHHHHHHCCCCCCCCEEEEEEEECCCCHHHHHHHHCCCCCCCCCEEEEECCCCC
TVGERVEPFFTLHFPDDCLVLIERHGRLPLPPYIEHAPDAADETRYQTVFAANPGAVAAP
CCCCCCCCEEEEECCCCEEEEEECCCCCCCCCHHCCCCCCCCCCCEEEEEECCCCCCCCC
TAGLHFDDAVLAALEARGVERATLTLHVGAGTFQPVRVENLAEHRMHSESYELTDALVEK
CCCCCCHHHHHHHHHHCCCEEEEEEEEECCCCCCCCHHHHHHHHHHCCCHHHHHHHHHHH
IAATRARGGRVIAVGTTSMRALEAAARDAQAAGRPLAATRAETDIFITPGYRFRVVDRLV
HHHHHCCCCEEEEEECCHHHHHHHHHHHHHHCCCCCEECCCCCEEEECCCCHHHHHHHHH
TNFHLPKSTLLMLVSAFAGIETIRAAYRHAIDARYRFFSYGDAMLLTRRDDAAEATHGGA
HHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEECCCEEEEEECCCHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Isomerases [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA