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The map label for this gene is arcB

Identifier: 126454759

GI number: 126454759

Start: 1950220

End: 1951230

Strand: Reverse

Name: arcB

Synonym: BURPS1106A_1986

Alternate gene names: 126454759

Gene position: 1951230-1950220 (Counterclockwise)

Preceding gene: 126453511

Following gene: 126452232

Centisome position: 48.92

GC content: 64.99

Gene sequence:

>1011_bases
ATGAGCTTCAACCTGCACAACCGCAACCTGCTGAGCCTGATCCACCACAACGCGCGCGAGCTGCGCTATCTGCTCGACCT
CGCGCGGGATCTCAAGCGCGCGAAGTACAGCGGCACCGAGCAGCCGCGCCTGCTGCGCAAGAACATCGCGCTCATCTTCG
AGAAGACCTCGACCCGCACGCGCTGCGCGTTCGAAGTCGCCGCATACGATCAGGGCGCGAACGTCACGTACATCGATCCG
GCTTCGTCGCAGATCGGCCACAAGGAAAGCATGAGGGACACGGCGCGCGTGCTCGGGCGGATGTACGACGCGATCGAGTA
CCGTGGCTTCAGCCAGGAGATCGTCGAGGAGCTCGCGCACCACGCGGGCGTGCCCGTCTTCAACGGGCTCACCGACGAAT
ACCATCCGACGCAGATGCTCGCCGACGTGATGACGATGCGCGAGCACAGCGACAAGCCGCTGCACGACATCCGCTACGCC
TATCTCGGCGACGCGCGCAACAACATGGGCAATTCGCTGCTCCTGATCGGCGCGAAGCTCGGGATGGACGTGCGGATCGG
CGCGCCGAAGTCGCTCTGGCCCGCGGCCGACTTCATCGCGCAGTGCGAGGCGTTCGCGGCCGAGAGCGGCGCGCGGCTCA
CGCTGACCGAGGACCCGTACGAAGCGGTCAAGGGCGTCGACTTCATCCACACCGACGTATGGGTGTCGATGGGCGAGCCC
GTCGAGGCCTGGGACGAGCGGATCAACGCGCTCCTGCCGTATCAGGTGAACCGCAAGCTGATCGAATCGACGGGCAATCC
GCGCACGCGCTTCATGCACTGCCTGCCGTCGTTCCACAACTGCGAGACGAAGGTCGGCAAGCAGATCGCCGAGCGCTATC
CGCACCTGCAGGACGGTATCGAAGTCACCGACGAAGTGTTCGAATCGCCGCGCTGCATCGCGTTCGAGCAGGCGGAAAAC
CGCATGCACACGATCAAGGCGGTCCTCGTGTCGACGCTCGGCGGCATCTGA

Upstream 100 bases:

>100_bases
ACCTGCCCGGTGCTGCGCGACCCCGTCGACTACTGAGCGCGGACCCAAGCGTCGCGGCGCGCGAGCGCCGCGCCCCCCGG
CAACCTAACGGAGAAACCAG

Downstream 100 bases:

>100_bases
AGGCGCGCCGCGCGCGATCGAGACGGGCGGCGCGCGAGGCCGCGCCGCCCGCACCGTCGGCACCGTTGACACAACAAGGA
GAAACATGATGCGTATCGTC

Product: ornithine carbamoyltransferase

Products: NA

Alternate protein names: OTCase

Number of amino acids: Translated: 336; Mature: 335

Protein sequence:

>336_residues
MSFNLHNRNLLSLIHHNARELRYLLDLARDLKRAKYSGTEQPRLLRKNIALIFEKTSTRTRCAFEVAAYDQGANVTYIDP
ASSQIGHKESMRDTARVLGRMYDAIEYRGFSQEIVEELAHHAGVPVFNGLTDEYHPTQMLADVMTMREHSDKPLHDIRYA
YLGDARNNMGNSLLLIGAKLGMDVRIGAPKSLWPAADFIAQCEAFAAESGARLTLTEDPYEAVKGVDFIHTDVWVSMGEP
VEAWDERINALLPYQVNRKLIESTGNPRTRFMHCLPSFHNCETKVGKQIAERYPHLQDGIEVTDEVFESPRCIAFEQAEN
RMHTIKAVLVSTLGGI

Sequences:

>Translated_336_residues
MSFNLHNRNLLSLIHHNARELRYLLDLARDLKRAKYSGTEQPRLLRKNIALIFEKTSTRTRCAFEVAAYDQGANVTYIDP
ASSQIGHKESMRDTARVLGRMYDAIEYRGFSQEIVEELAHHAGVPVFNGLTDEYHPTQMLADVMTMREHSDKPLHDIRYA
YLGDARNNMGNSLLLIGAKLGMDVRIGAPKSLWPAADFIAQCEAFAAESGARLTLTEDPYEAVKGVDFIHTDVWVSMGEP
VEAWDERINALLPYQVNRKLIESTGNPRTRFMHCLPSFHNCETKVGKQIAERYPHLQDGIEVTDEVFESPRCIAFEQAEN
RMHTIKAVLVSTLGGI
>Mature_335_residues
SFNLHNRNLLSLIHHNARELRYLLDLARDLKRAKYSGTEQPRLLRKNIALIFEKTSTRTRCAFEVAAYDQGANVTYIDPA
SSQIGHKESMRDTARVLGRMYDAIEYRGFSQEIVEELAHHAGVPVFNGLTDEYHPTQMLADVMTMREHSDKPLHDIRYAY
LGDARNNMGNSLLLIGAKLGMDVRIGAPKSLWPAADFIAQCEAFAAESGARLTLTEDPYEAVKGVDFIHTDVWVSMGEPV
EAWDERINALLPYQVNRKLIESTGNPRTRFMHCLPSFHNCETKVGKQIAERYPHLQDGIEVTDEVFESPRCIAFEQAENR
MHTIKAVLVSTLGGI

Specific function: Arginine biosynthesis; sixth step. [C]

COG id: COG0078

COG function: function code E; Ornithine carbamoyltransferase

Gene ontology:

Cell location: Cytoplasm (Probable)

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ATCase/OTCase family

Homologues:

Organism=Homo sapiens, GI38788445, Length=330, Percent_Identity=39.0909090909091, Blast_Score=214, Evalue=7e-56,
Organism=Escherichia coli, GI1790703, Length=331, Percent_Identity=58.6102719033233, Blast_Score=410, Evalue=1e-116,
Organism=Escherichia coli, GI1786469, Length=332, Percent_Identity=57.8313253012048, Blast_Score=404, Evalue=1e-114,
Organism=Escherichia coli, GI48994908, Length=381, Percent_Identity=24.6719160104987, Blast_Score=80, Evalue=3e-16,
Organism=Escherichia coli, GI2367364, Length=153, Percent_Identity=37.2549019607843, Blast_Score=68, Evalue=7e-13,
Organism=Saccharomyces cerevisiae, GI6322373, Length=330, Percent_Identity=31.2121212121212, Blast_Score=154, Evalue=2e-38,
Organism=Drosophila melanogaster, GI24642586, Length=341, Percent_Identity=24.3401759530792, Blast_Score=71, Evalue=1e-12,

Paralogues:

None

Copy number: 140 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 2066 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. [C]

Swissprot (AC and ID): OTCC_BURMA (Q62KD8)

Other databases:

- EMBL:   CP000010
- RefSeq:   YP_102831.1
- ProteinModelPortal:   Q62KD8
- SMR:   Q62KD8
- GeneID:   3089720
- GenomeReviews:   CP000010_GR
- KEGG:   bma:BMA1146
- TIGR:   BMA1146
- HOGENOM:   HBG579429
- OMA:   DFRIFAP
- PhylomeDB:   Q62KD8
- ProtClustDB:   PRK02102
- BioCyc:   BMAL243160:BMA_1146-MONOMER
- BRENDA:   2.1.3.3
- HAMAP:   MF_01109
- InterPro:   IPR006132
- InterPro:   IPR006130
- InterPro:   IPR006131
- InterPro:   IPR002292
- PRINTS:   PR00100
- PRINTS:   PR00102
- TIGRFAMs:   TIGR00658

Pfam domain/function: PF00185 OTCace; PF02729 OTCace_N; SSF53671 Asp/Orn_carbamoyltranf

EC number: =2.1.3.3

Molecular weight: Translated: 38018; Mature: 37887

Theoretical pI: Translated: 6.51; Mature: 6.51

Prosite motif: PS00097 CARBAMOYLTRANSFERASE

Important sites: BINDING 108-108 BINDING 135-135

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSFNLHNRNLLSLIHHNARELRYLLDLARDLKRAKYSGTEQPRLLRKNIALIFEKTSTRT
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHEEECCCCCC
RCAFEVAAYDQGANVTYIDPASSQIGHKESMRDTARVLGRMYDAIEYRGFSQEIVEELAH
CEEEEEEEECCCCCEEEECCCCHHCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHH
HAGVPVFNGLTDEYHPTQMLADVMTMREHSDKPLHDIRYAYLGDARNNMGNSLLLIGAKL
HCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHCCHHCCCCCEEEEEEECC
GMDVRIGAPKSLWPAADFIAQCEAFAAESGARLTLTEDPYEAVKGVDFIHTDVWVSMGEP
CCEEEECCCCCCCHHHHHHHHHHHHHHCCCCEEEECCCHHHHHCCCHHHHHHHHHCCCCC
VEAWDERINALLPYQVNRKLIESTGNPRTRFMHCLPSFHNCETKVGKQIAERYPHLQDGI
HHHHHHHHHCCCCHHHHHHHHHCCCCHHHHHHHHCCCCCCHHHHHHHHHHHHCCCHHCHH
EVTDEVFESPRCIAFEQAENRMHTIKAVLVSTLGGI
HHHHHHHCCCCEEEHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
SFNLHNRNLLSLIHHNARELRYLLDLARDLKRAKYSGTEQPRLLRKNIALIFEKTSTRT
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHEEECCCCCC
RCAFEVAAYDQGANVTYIDPASSQIGHKESMRDTARVLGRMYDAIEYRGFSQEIVEELAH
CEEEEEEEECCCCCEEEECCCCHHCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHH
HAGVPVFNGLTDEYHPTQMLADVMTMREHSDKPLHDIRYAYLGDARNNMGNSLLLIGAKL
HCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHCCHHCCCCCEEEEEEECC
GMDVRIGAPKSLWPAADFIAQCEAFAAESGARLTLTEDPYEAVKGVDFIHTDVWVSMGEP
CCEEEECCCCCCCHHHHHHHHHHHHHHCCCCEEEECCCHHHHHCCCHHHHHHHHHCCCCC
VEAWDERINALLPYQVNRKLIESTGNPRTRFMHCLPSFHNCETKVGKQIAERYPHLQDGI
HHHHHHHHHCCCCHHHHHHHHHCCCCHHHHHHHHCCCCCCHHHHHHHHHHHHCCCHHCHH
EVTDEVFESPRCIAFEQAENRMHTIKAVLVSTLGGI
HHHHHHHCCCCEEEHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA