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The map label for this gene is ybdL [H]

Identifier: 126454689

GI number: 126454689

Start: 3928156

End: 3929310

Strand: Reverse

Name: ybdL [H]

Synonym: BURPS1106A_4026

Alternate gene names: 126454689

Gene position: 3929310-3928156 (Counterclockwise)

Preceding gene: 126451962

Following gene: 126452725

Centisome position: 98.52

GC content: 69.35

Gene sequence:

>1155_bases
ATGCAGAGCGCCGCCGCGCCCCGTTCGAAGCTGCCCGACGTCGGCACGACGATCTTCACGGTCATCGGCCAGCTCGCCGC
CGAGCACGAGGCGCTGAATCTGTCGCAGGGCGCGCCGAATTTCGCGCCCGATCCGGCGCTCGTCGAGCGCGTCGCCCGCG
CGATGCGAGACGGGCACAACCAGTACGCGCCGATGGCGGGCATCGCCGCGCTGCGCGAGGCGCTCGCCGTGAAGACCGAG
CGCCTGTACGGCGAGCGCTACGATCCGGACTCCGAAGTCACCATCGTCGCGAGCGCGAGCGAGGGGCTCTACGCGGCGAT
CAGCGCGCTCGTCCATCCGGGCGATGAGGTGATCTACTTCGAGCCGTCGTTCGACAGCTACGCGCCGATCGTCCGGCTGC
AGGGCGCGACGCCCGTCGCGATCAGGCTGTCGCCCGAGCGCTTTCGCGTGAACTGGGACGAGGTGGCCGCGAAGATCACG
CCGCGCACGCGGATGCTGATCGTCAACACGCCGCACAACCCGAGCGCGACGATCCTCGGCGAGGCCGACGTCGCGCGTCT
CGCGCAGCTCGTCGCGGGCACCGACATCGTGGTGCTGTCCGACGAGGTGTACGAGCACGTCGTGTTCGACGGCGCGCGCC
ATCACAGCATGGCGCGCGATCGCGCGCTCGCCGAGCGCAGCGTGATCGTGTCGTCGTTCGGCAAGTCGTATCACGTGACG
GGCTGGCGCGTCGGCTACTGCCTCGCGCCCGCCGAGCTCACGCGCGAGCTGCGCAAGGTCCATCAGTTCATGACGTTCGC
GGCCGATACGCCGATGCAGCATGCGTTCGCGGCGGCGCTCGCGGAGCCGGCGAGCTATCTCGAGCTCGGCGCGTTCTACG
AGCGCAAGCGCGACCTGCTCGTGCGCGAGCTGGCCGGCTCGCGCTTCGAGCTGCTGCCGAGCGAGGGTTCGTTCTTCATG
CTCGCGCGCTTCGGGCATTTTTCGGACGAATCGGACGCCGACTTCGTGCTGCGTGCGATTCGCGACGCACGCGTCGCGAC
GATTCCGCTGTCCGCGTTCTACGCGGACGGCGCGAACACCGGCTGCATCCGTTTGAGCTTTTCGAAGGACGACGCGACGC
TCGTCGAAGGCGCGCGCCGCCTGTGCAGCCTCTGA

Upstream 100 bases:

>100_bases
AACTTTCGATTGCCGCCGGATATTGGCTCGGGCCCAATCCGCATCGTTGCCCCGCGCGCCGGCGATGGCCGCGCGCCCGT
TCACGAGCCCAGGAGGATCC

Downstream 100 bases:

>100_bases
CGCGCGCGGTGCCGGCCGCTGCGGACATGACCCGATCTCAAGGAGAAACATCGATGAAACGATTGCAATTCTGGTTCGCG
CTCGCCTGTGCATTGGGTGC

Product: putative aminotransferase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 384; Mature: 384

Protein sequence:

>384_residues
MQSAAAPRSKLPDVGTTIFTVIGQLAAEHEALNLSQGAPNFAPDPALVERVARAMRDGHNQYAPMAGIAALREALAVKTE
RLYGERYDPDSEVTIVASASEGLYAAISALVHPGDEVIYFEPSFDSYAPIVRLQGATPVAIRLSPERFRVNWDEVAAKIT
PRTRMLIVNTPHNPSATILGEADVARLAQLVAGTDIVVLSDEVYEHVVFDGARHHSMARDRALAERSVIVSSFGKSYHVT
GWRVGYCLAPAELTRELRKVHQFMTFAADTPMQHAFAAALAEPASYLELGAFYERKRDLLVRELAGSRFELLPSEGSFFM
LARFGHFSDESDADFVLRAIRDARVATIPLSAFYADGANTGCIRLSFSKDDATLVEGARRLCSL

Sequences:

>Translated_384_residues
MQSAAAPRSKLPDVGTTIFTVIGQLAAEHEALNLSQGAPNFAPDPALVERVARAMRDGHNQYAPMAGIAALREALAVKTE
RLYGERYDPDSEVTIVASASEGLYAAISALVHPGDEVIYFEPSFDSYAPIVRLQGATPVAIRLSPERFRVNWDEVAAKIT
PRTRMLIVNTPHNPSATILGEADVARLAQLVAGTDIVVLSDEVYEHVVFDGARHHSMARDRALAERSVIVSSFGKSYHVT
GWRVGYCLAPAELTRELRKVHQFMTFAADTPMQHAFAAALAEPASYLELGAFYERKRDLLVRELAGSRFELLPSEGSFFM
LARFGHFSDESDADFVLRAIRDARVATIPLSAFYADGANTGCIRLSFSKDDATLVEGARRLCSL
>Mature_384_residues
MQSAAAPRSKLPDVGTTIFTVIGQLAAEHEALNLSQGAPNFAPDPALVERVARAMRDGHNQYAPMAGIAALREALAVKTE
RLYGERYDPDSEVTIVASASEGLYAAISALVHPGDEVIYFEPSFDSYAPIVRLQGATPVAIRLSPERFRVNWDEVAAKIT
PRTRMLIVNTPHNPSATILGEADVARLAQLVAGTDIVVLSDEVYEHVVFDGARHHSMARDRALAERSVIVSSFGKSYHVT
GWRVGYCLAPAELTRELRKVHQFMTFAADTPMQHAFAAALAEPASYLELGAFYERKRDLLVRELAGSRFELLPSEGSFFM
LARFGHFSDESDADFVLRAIRDARVATIPLSAFYADGANTGCIRLSFSKDDATLVEGARRLCSL

Specific function: Shows aminotransferase activity with methionine and histidine as substrates, and to a lesser extent also with phenylalanine [H]

COG id: COG0436

COG function: function code E; Aspartate/tyrosine/aromatic aminotransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Homo sapiens, GI95147551, Length=386, Percent_Identity=33.160621761658, Blast_Score=204, Evalue=8e-53,
Organism=Homo sapiens, GI169881279, Length=386, Percent_Identity=33.160621761658, Blast_Score=204, Evalue=8e-53,
Organism=Homo sapiens, GI56713254, Length=396, Percent_Identity=30.050505050505, Blast_Score=202, Evalue=6e-52,
Organism=Homo sapiens, GI56713256, Length=392, Percent_Identity=30.3571428571429, Blast_Score=201, Evalue=8e-52,
Organism=Homo sapiens, GI169881281, Length=384, Percent_Identity=28.90625, Blast_Score=156, Evalue=2e-38,
Organism=Homo sapiens, GI4507369, Length=377, Percent_Identity=23.8726790450928, Blast_Score=91, Evalue=3e-18,
Organism=Escherichia coli, GI1786816, Length=379, Percent_Identity=52.7704485488127, Blast_Score=394, Evalue=1e-111,
Organism=Escherichia coli, GI1788722, Length=337, Percent_Identity=25.8160237388724, Blast_Score=109, Evalue=3e-25,
Organism=Escherichia coli, GI1788627, Length=339, Percent_Identity=25.6637168141593, Blast_Score=94, Evalue=1e-20,
Organism=Caenorhabditis elegans, GI71994472, Length=412, Percent_Identity=31.3106796116505, Blast_Score=199, Evalue=2e-51,
Organism=Caenorhabditis elegans, GI71994476, Length=412, Percent_Identity=31.3106796116505, Blast_Score=199, Evalue=2e-51,
Organism=Caenorhabditis elegans, GI17567369, Length=409, Percent_Identity=28.8508557457213, Blast_Score=183, Evalue=1e-46,
Organism=Caenorhabditis elegans, GI17567663, Length=337, Percent_Identity=24.0356083086053, Blast_Score=88, Evalue=9e-18,
Organism=Saccharomyces cerevisiae, GI6322401, Length=390, Percent_Identity=28.2051282051282, Blast_Score=164, Evalue=2e-41,
Organism=Drosophila melanogaster, GI28573069, Length=393, Percent_Identity=32.3155216284987, Blast_Score=192, Evalue=3e-49,
Organism=Drosophila melanogaster, GI24646114, Length=393, Percent_Identity=32.3155216284987, Blast_Score=192, Evalue=3e-49,
Organism=Drosophila melanogaster, GI28573067, Length=393, Percent_Identity=32.3155216284987, Blast_Score=192, Evalue=3e-49,
Organism=Drosophila melanogaster, GI28573065, Length=393, Percent_Identity=32.3155216284987, Blast_Score=192, Evalue=3e-49,
Organism=Drosophila melanogaster, GI18859735, Length=388, Percent_Identity=25, Blast_Score=78, Evalue=1e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004839
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00155 Aminotran_1_2 [H]

EC number: 2.6.1.- [C]

Molecular weight: Translated: 41970; Mature: 41970

Theoretical pI: Translated: 5.97; Mature: 5.97

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQSAAAPRSKLPDVGTTIFTVIGQLAAEHEALNLSQGAPNFAPDPALVERVARAMRDGHN
CCCCCCCHHCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHCCCC
QYAPMAGIAALREALAVKTERLYGERYDPDSEVTIVASASEGLYAAISALVHPGDEVIYF
CCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEECCCCHHHHHHHHHCCCCCEEEE
EPSFDSYAPIVRLQGATPVAIRLSPERFRVNWDEVAAKITPRTRMLIVNTPHNPSATILG
CCCCCCCCCEEEECCCCEEEEEECHHHHCCCHHHHHHEECCCEEEEEEECCCCCCEEEEC
EADVARLAQLVAGTDIVVLSDEVYEHVVFDGARHHSMARDRALAERSVIVSSFGKSYHVT
CHHHHHHHHHHCCCCEEEECHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCEEEC
GWRVGYCLAPAELTRELRKVHQFMTFAADTPMQHAFAAALAEPASYLELGAFYERKRDLL
EEEEEEEECHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHH
VRELAGSRFELLPSEGSFFMLARFGHFSDESDADFVLRAIRDARVATIPLSAFYADGANT
HHHHCCCCEEEECCCCCEEEEEECCCCCCCCCHHHHHHHHHCCCEEEEEHHHEECCCCCC
GCIRLSFSKDDATLVEGARRLCSL
CEEEEEECCCCHHHHHHHHHHHCC
>Mature Secondary Structure
MQSAAAPRSKLPDVGTTIFTVIGQLAAEHEALNLSQGAPNFAPDPALVERVARAMRDGHN
CCCCCCCHHCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHCCCC
QYAPMAGIAALREALAVKTERLYGERYDPDSEVTIVASASEGLYAAISALVHPGDEVIYF
CCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEECCCCHHHHHHHHHCCCCCEEEE
EPSFDSYAPIVRLQGATPVAIRLSPERFRVNWDEVAAKITPRTRMLIVNTPHNPSATILG
CCCCCCCCCEEEECCCCEEEEEECHHHHCCCHHHHHHEECCCEEEEEEECCCCCCEEEEC
EADVARLAQLVAGTDIVVLSDEVYEHVVFDGARHHSMARDRALAERSVIVSSFGKSYHVT
CHHHHHHHHHHCCCCEEEECHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCEEEC
GWRVGYCLAPAELTRELRKVHQFMTFAADTPMQHAFAAALAEPASYLELGAFYERKRDLL
EEEEEEEECHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHH
VRELAGSRFELLPSEGSFFMLARFGHFSDESDADFVLRAIRDARVATIPLSAFYADGANT
HHHHCCCCEEEECCCCCEEEEEECCCCCCCCCHHHHHHHHHCCCEEEEEHHHEECCCCCC
GCIRLSFSKDDATLVEGARRLCSL
CEEEEEECCCCHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: Pyridoxal Phosphate. [C]

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8905232; 9278503 [H]