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The map label for this gene is tadA [H]

Identifier: 126454685

GI number: 126454685

Start: 2396154

End: 2396750

Strand: Reverse

Name: tadA [H]

Synonym: BURPS1106A_2437

Alternate gene names: 126454685

Gene position: 2396750-2396154 (Counterclockwise)

Preceding gene: 126453557

Following gene: 126451817

Centisome position: 60.09

GC content: 74.87

Gene sequence:

>597_bases
GTGAGGCCCGCCGGCGCGCCCGCGTCCGGCGCCGAGCTCGACGATTCAACGCAATCCCCGCCGCACGCCGCGTTGCTTTC
CGCGGCCGCCGAGCGCGACCGCCGCTACATGCGCCTCGCGCTCGCCGCCGCCGAGGAGGCGCGCGCGGCGGGCGAGGTGC
CGGTCGGCGCGGTGATCGTGCGCGGCGACGAAGTGATCGCGCGGGGCTTCAATCATCCGATCGGCGGCCACGATCCGTCC
GCCCACGCCGAGATGGCCGCGCTGCGCGCCGCCGCGCGCGCGCTGCGCAATTACCGGATGCCGGGCTGCGAACTGTACGT
GACGCTCGAGCCGTGCCTGATGTGCTCGGGGGCGATCATGCATGCGCGGATCGCGCGCGTCGTGTTCGGCGCGCCCGATC
CGAAGACGGGCGCATGCGGCAGCGTCGTCGATGCGTTCGCGGATGCGCGCCTGAACCATCACACGACGGTCGAAGGCGGC
GTGCTCGCCGACGAATGCGGCGCGGTGCTCAAGTCGTTCTTCGCGCAGCGGCGGCAGGCGGTTCGCGAGGCCCGCCGCGC
GCAGCAGGCGCCCGGCGCGCCGCCGCGCGACGAGTGA

Upstream 100 bases:

>100_bases
GCGGCGGCCCGATGGTCGTGCCGCGCGAATACTGCCGTCGCATCGCCGAGCGGCTGTCCGAGCGTGTGCTCGGCGACGCG
CAGGGCGAAGCGGGGGCGAT

Downstream 100 bases:

>100_bases
ACCGCGCGGCGCGGGACGCCTCTAACTACGTCCGATCGATTCTTCCTGCGAATTCATGATTTCCACGCCCTGCACGCCGC
GCACGATTCGTCTGCTCGCC

Product: cytidine/deoxycytidylate deaminase family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 198; Mature: 198

Protein sequence:

>198_residues
MRPAGAPASGAELDDSTQSPPHAALLSAAAERDRRYMRLALAAAEEARAAGEVPVGAVIVRGDEVIARGFNHPIGGHDPS
AHAEMAALRAAARALRNYRMPGCELYVTLEPCLMCSGAIMHARIARVVFGAPDPKTGACGSVVDAFADARLNHHTTVEGG
VLADECGAVLKSFFAQRRQAVREARRAQQAPGAPPRDE

Sequences:

>Translated_198_residues
MRPAGAPASGAELDDSTQSPPHAALLSAAAERDRRYMRLALAAAEEARAAGEVPVGAVIVRGDEVIARGFNHPIGGHDPS
AHAEMAALRAAARALRNYRMPGCELYVTLEPCLMCSGAIMHARIARVVFGAPDPKTGACGSVVDAFADARLNHHTTVEGG
VLADECGAVLKSFFAQRRQAVREARRAQQAPGAPPRDE
>Mature_198_residues
MRPAGAPASGAELDDSTQSPPHAALLSAAAERDRRYMRLALAAAEEARAAGEVPVGAVIVRGDEVIARGFNHPIGGHDPS
AHAEMAALRAAARALRNYRMPGCELYVTLEPCLMCSGAIMHARIARVVFGAPDPKTGACGSVVDAFADARLNHHTTVEGG
VLADECGAVLKSFFAQRRQAVREARRAQQAPGAPPRDE

Specific function: Deaminates adenosine-34 to inosine in tRNA-Arg2 [H]

COG id: COG0590

COG function: function code FJ; Cytosine/adenosine deaminases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the cytidine and deoxycytidylate deaminase family [H]

Homologues:

Organism=Homo sapiens, GI124107608, Length=161, Percent_Identity=33.5403726708075, Blast_Score=84, Evalue=8e-17,
Organism=Homo sapiens, GI19923945, Length=69, Percent_Identity=49.2753623188406, Blast_Score=64, Evalue=7e-11,
Organism=Escherichia coli, GI145693172, Length=155, Percent_Identity=51.6129032258064, Blast_Score=172, Evalue=2e-44,
Organism=Caenorhabditis elegans, GI17541138, Length=151, Percent_Identity=34.4370860927152, Blast_Score=85, Evalue=3e-17,
Organism=Caenorhabditis elegans, GI17554608, Length=98, Percent_Identity=37.7551020408163, Blast_Score=82, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI17555996, Length=96, Percent_Identity=36.4583333333333, Blast_Score=65, Evalue=2e-11,
Organism=Drosophila melanogaster, GI21355527, Length=145, Percent_Identity=38.6206896551724, Blast_Score=92, Evalue=2e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016192
- InterPro:   IPR002125
- InterPro:   IPR016193 [H]

Pfam domain/function: PF00383 dCMP_cyt_deam_1 [H]

EC number: NA

Molecular weight: Translated: 20797; Mature: 20797

Theoretical pI: Translated: 7.54; Mature: 7.54

Prosite motif: PS00903 CYT_DCMP_DEAMINASES

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.5 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
5.6 %Cys+Met (Translated Protein)
2.5 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
5.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRPAGAPASGAELDDSTQSPPHAALLSAAAERDRRYMRLALAAAEEARAAGEVPVGAVIV
CCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEE
RGDEVIARGFNHPIGGHDPSAHAEMAALRAAARALRNYRMPGCELYVTLEPCLMCSGAIM
ECHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCEEEEEECHHHHHHHHHH
HARIARVVFGAPDPKTGACGSVVDAFADARLNHHTTVEGGVLADECGAVLKSFFAQRRQA
HHHHHHHHHCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHH
VREARRAQQAPGAPPRDE
HHHHHHHHHCCCCCCCCC
>Mature Secondary Structure
MRPAGAPASGAELDDSTQSPPHAALLSAAAERDRRYMRLALAAAEEARAAGEVPVGAVIV
CCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEE
RGDEVIARGFNHPIGGHDPSAHAEMAALRAAARALRNYRMPGCELYVTLEPCLMCSGAIM
ECHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCEEEEEECHHHHHHHHHH
HARIARVVFGAPDPKTGACGSVVDAFADARLNHHTTVEGGVLADECGAVLKSFFAQRRQA
HHHHHHHHHCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHH
VREARRAQQAPGAPPRDE
HHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11677608; 12644504 [H]