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The map label for this gene is prkA [H]

Identifier: 126454647

GI number: 126454647

Start: 1828296

End: 1830218

Strand: Direct

Name: prkA [H]

Synonym: BURPS1106A_1873

Alternate gene names: 126454647

Gene position: 1828296-1830218 (Clockwise)

Preceding gene: 126451531

Following gene: 126452511

Centisome position: 45.84

GC content: 61.05

Gene sequence:

>1923_bases
ATGGATATTTACAGCAGCTTCGCGAACCGCTTCGAAAAAACGCGAGAGGAAGAGTTCTCGCTGGAGGAGTATCTCGCGCT
CTGCAAGAACGATCCGTCAGCGTACGCCGCGGCAGGCGAACGCATGCTGGAGGCCATCGGGGAACCGGAACAGATCGACA
CGCGCAACGATCCGCGCTTGTCGCGGATTTTCGCGAACAAGGTGATCAAGGTATACCCCGCGTTCCGCGAGTTCTACGGC
ATGGAAGAGGTGATCGAGCAGGTGGTCGCCTATTTCCGCCACGCGGCGCAGGGCCTCGAGGAGAAGAAGCAGATTCTCTA
CCTGCTCGGGCCGGTGGGCGGCGGCAAGTCGTCGATCGCCGAGCGCCTGAAGCAACTGATGGAGCGCGTGCCGTTCTATG
CGCTCAAGGGCTCGCCCGTCAACGAATCGCCGCTTGGCCTGTTCGATTACGACGAAGACGGCCCGATTCTCGAAGAGCAG
TACGGCATTCCGCGCCGCTACCTGAAGAGCATCCTGAGTCCGTGGGCGGTCAAGCGCCTGCACGAATACAACGGCGACAT
CCGGCGCTTTCGCGTCGTGCGCCGCTATCCGTCGATCCTGCGGCAGATCGGCATCGCGAAGACCGAGCCGGGCGACGAGA
ATAATCAGGACATCTCGTCGCTCGTGGGCAAGGTCGACATCCGCAAGCTCGAGCAATACGCGCAGGACGACGCCGACGCG
TACAGCTACTCGGGCGGCTTGTGCCTCGCGAACCAGGGGCTGCTCGAGTTCGTCGAAATGTTCAAGGCGCCGATCAAGGT
GCTGCACCCGCTCCTCACCGCGACGCAGGAGGGCAACTTCAAGGGCACCGAAGGCTTCGGCGCGATTCCGTTCGACGGCA
TCATCCTCGCGCACTCGAACGAGTCCGAGTGGAAGGCGTTCCGCAACAACCGCAACAACGAGGCGCTGCTCGACCGGATC
TTCGTCGTCAAGGTGCCGTACTGCCTGCGCGTGTCGGAGGAGATCAAGATCTACGAGAAGCTGATCCGCAACTCGTCGCT
CGCCGAGGCGGTGTGCGCGCCCGGCACGCTGAAGATGATGGCGCAGCTCTCGGTGCTCACGCGCCTGCACGAACCGGAGA
ACTCGAGCCTCTTTTCGAAGATGCAGGTGTACGACGGCGAGAATCTGAAGGACACCGATCCGAAGGCGAAGTCGTATCAG
GAATATCGCGATTACGCGGGCGTCGACGAAGGGATGACGGGCGTGTCCACGCGCTTCGCGTTCAAGATCCTCTCGCGCGT
GTTCAACTTCGATTCGACCGAAGTGGCGGCGAACCCGGTGCACCTGATGTACGTGCTCGAGCAGCAGATCGAGCGCGAGC
AGTTCCCGCCGGAAACCGAGCAGAAGTATCTGTCGTTCGTGAAGGACCTGCTTGCATCGCGCTACGCCGAGTTCATCGGC
AAGGAGATCCAGACCGCGTACCTCGAATCGTATTCGGAATACGGGCAGAACATCTTCGACCGCTATGTCACGTACGCGGA
TTTCTGGATCCAGGATCAGGAATTCCGCGATCACGACACGGGCGAGAGCTTCGATCGCGCGGCGCTCAATGCCGAGCTCG
AGAAGATCGAGAAGCCGGCGGGCATCAGCAATCCGAAGGATTTCCGCAACGAGATCGTGAATTTCGTGCTGCGCGCCCGT
GCGGCGAACGGCGGCAAGAACCCGGCGTGGGTCAGCTACGAGAAGCTGCGCGTCGTGATCGAAAAGAAGATGTTCTCGAA
CACGGAGGAATTGTTGCCGGTCATCTCGTTCAACGCGAAGGGCTCGGCGGAGGAACAGCGCAAGCACGAAGACTTTGTGA
ACCGGATGGTCGCGAAGGGCTACACGCCGAAGCAGGTGCGGCTCCTCTGCGACTGGTATCTGCGCGTGCGCAAGTCGTCA
TGA

Upstream 100 bases:

>100_bases
AAAAAAAAAGTAAATGGGTTTAGGATGAAATCGAACGGTCCTGCTTCGACACGATCTATACGAAGGCAAGATCGTCTTCA
GACTCAGGCGAGGAGGTAGC

Downstream 100 bases:

>100_bases
CCTGCGCGACGCGACGCCCGCGCGGCCGCGCGCGGGCACCTTGAGAGACGCCGCCCGCATTGCGGCAGCCCCGCGTGCGC
GGCGTGCGTCCCGGCGTATC

Product: serine protein kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 640; Mature: 640

Protein sequence:

>640_residues
MDIYSSFANRFEKTREEEFSLEEYLALCKNDPSAYAAAGERMLEAIGEPEQIDTRNDPRLSRIFANKVIKVYPAFREFYG
MEEVIEQVVAYFRHAAQGLEEKKQILYLLGPVGGGKSSIAERLKQLMERVPFYALKGSPVNESPLGLFDYDEDGPILEEQ
YGIPRRYLKSILSPWAVKRLHEYNGDIRRFRVVRRYPSILRQIGIAKTEPGDENNQDISSLVGKVDIRKLEQYAQDDADA
YSYSGGLCLANQGLLEFVEMFKAPIKVLHPLLTATQEGNFKGTEGFGAIPFDGIILAHSNESEWKAFRNNRNNEALLDRI
FVVKVPYCLRVSEEIKIYEKLIRNSSLAEAVCAPGTLKMMAQLSVLTRLHEPENSSLFSKMQVYDGENLKDTDPKAKSYQ
EYRDYAGVDEGMTGVSTRFAFKILSRVFNFDSTEVAANPVHLMYVLEQQIEREQFPPETEQKYLSFVKDLLASRYAEFIG
KEIQTAYLESYSEYGQNIFDRYVTYADFWIQDQEFRDHDTGESFDRAALNAELEKIEKPAGISNPKDFRNEIVNFVLRAR
AANGGKNPAWVSYEKLRVVIEKKMFSNTEELLPVISFNAKGSAEEQRKHEDFVNRMVAKGYTPKQVRLLCDWYLRVRKSS

Sequences:

>Translated_640_residues
MDIYSSFANRFEKTREEEFSLEEYLALCKNDPSAYAAAGERMLEAIGEPEQIDTRNDPRLSRIFANKVIKVYPAFREFYG
MEEVIEQVVAYFRHAAQGLEEKKQILYLLGPVGGGKSSIAERLKQLMERVPFYALKGSPVNESPLGLFDYDEDGPILEEQ
YGIPRRYLKSILSPWAVKRLHEYNGDIRRFRVVRRYPSILRQIGIAKTEPGDENNQDISSLVGKVDIRKLEQYAQDDADA
YSYSGGLCLANQGLLEFVEMFKAPIKVLHPLLTATQEGNFKGTEGFGAIPFDGIILAHSNESEWKAFRNNRNNEALLDRI
FVVKVPYCLRVSEEIKIYEKLIRNSSLAEAVCAPGTLKMMAQLSVLTRLHEPENSSLFSKMQVYDGENLKDTDPKAKSYQ
EYRDYAGVDEGMTGVSTRFAFKILSRVFNFDSTEVAANPVHLMYVLEQQIEREQFPPETEQKYLSFVKDLLASRYAEFIG
KEIQTAYLESYSEYGQNIFDRYVTYADFWIQDQEFRDHDTGESFDRAALNAELEKIEKPAGISNPKDFRNEIVNFVLRAR
AANGGKNPAWVSYEKLRVVIEKKMFSNTEELLPVISFNAKGSAEEQRKHEDFVNRMVAKGYTPKQVRLLCDWYLRVRKSS
>Mature_640_residues
MDIYSSFANRFEKTREEEFSLEEYLALCKNDPSAYAAAGERMLEAIGEPEQIDTRNDPRLSRIFANKVIKVYPAFREFYG
MEEVIEQVVAYFRHAAQGLEEKKQILYLLGPVGGGKSSIAERLKQLMERVPFYALKGSPVNESPLGLFDYDEDGPILEEQ
YGIPRRYLKSILSPWAVKRLHEYNGDIRRFRVVRRYPSILRQIGIAKTEPGDENNQDISSLVGKVDIRKLEQYAQDDADA
YSYSGGLCLANQGLLEFVEMFKAPIKVLHPLLTATQEGNFKGTEGFGAIPFDGIILAHSNESEWKAFRNNRNNEALLDRI
FVVKVPYCLRVSEEIKIYEKLIRNSSLAEAVCAPGTLKMMAQLSVLTRLHEPENSSLFSKMQVYDGENLKDTDPKAKSYQ
EYRDYAGVDEGMTGVSTRFAFKILSRVFNFDSTEVAANPVHLMYVLEQQIEREQFPPETEQKYLSFVKDLLASRYAEFIG
KEIQTAYLESYSEYGQNIFDRYVTYADFWIQDQEFRDHDTGESFDRAALNAELEKIEKPAGISNPKDFRNEIVNFVLRAR
AANGGKNPAWVSYEKLRVVIEKKMFSNTEELLPVISFNAKGSAEEQRKHEDFVNRMVAKGYTPKQVRLLCDWYLRVRKSS

Specific function: Unknown

COG id: COG2766

COG function: function code T; Putative Ser protein kinase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the prkA family [H]

Homologues:

Organism=Escherichia coli, GI1788083, Length=644, Percent_Identity=75.1552795031056, Blast_Score=1029, Evalue=0.0,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013153
- InterPro:   IPR010650
- InterPro:   IPR016230 [H]

Pfam domain/function: PF08298 AAA_PrkA; PF06798 PrkA [H]

EC number: NA

Molecular weight: Translated: 73477; Mature: 73477

Theoretical pI: Translated: 5.35; Mature: 5.35

Prosite motif: PS00107 PROTEIN_KINASE_ATP

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDIYSSFANRFEKTREEEFSLEEYLALCKNDPSAYAAAGERMLEAIGEPEQIDTRNDPRL
CCHHHHHHHHHHHHHHHHCCHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCCCCCCCHHH
SRIFANKVIKVYPAFREFYGMEEVIEQVVAYFRHAAQGLEEKKQILYLLGPVGGGKSSIA
HHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHEEEEECCCCCCHHHHH
ERLKQLMERVPFYALKGSPVNESPLGLFDYDEDGPILEEQYGIPRRYLKSILSPWAVKRL
HHHHHHHHHCCEEEECCCCCCCCCCCCCCCCCCCCCHHHHCCCCHHHHHHHHCHHHHHHH
HEYNGDIRRFRVVRRYPSILRQIGIAKTEPGDENNQDISSLVGKVDIRKLEQYAQDDADA
HHHCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCHH
YSYSGGLCLANQGLLEFVEMFKAPIKVLHPLLTATQEGNFKGTEGFGAIPFDGIILAHSN
HCCCCCEEECCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCEEEEECC
ESEWKAFRNNRNNEALLDRIFVVKVPYCLRVSEEIKIYEKLIRNSSLAEAVCAPGTLKMM
CHHHHHHHCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCHHHHHHHCCHHHHHH
AQLSVLTRLHEPENSSLFSKMQVYDGENLKDTDPKAKSYQEYRDYAGVDEGMTGVSTRFA
HHHHHHHHHCCCCCCHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHCCCCCCCCHHHHHHH
FKILSRVFNFDSTEVAANPVHLMYVLEQQIEREQFPPETEQKYLSFVKDLLASRYAEFIG
HHHHHHHHCCCCCHHCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHH
KEIQTAYLESYSEYGQNIFDRYVTYADFWIQDQEFRDHDTGESFDRAALNAELEKIEKPA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHCCCCCCCHHHHHHHHHHHHHHCCCC
GISNPKDFRNEIVNFVLRARAANGGKNPAWVSYEKLRVVIEKKMFSNTEELLPVISFNAK
CCCCHHHHHHHHHHHHHHHHHCCCCCCCCEEHHHHHHHHHHHHHHCCHHHHHHHHCCCCC
GSAEEQRKHEDFVNRMVAKGYTPKQVRLLCDWYLRVRKSS
CCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MDIYSSFANRFEKTREEEFSLEEYLALCKNDPSAYAAAGERMLEAIGEPEQIDTRNDPRL
CCHHHHHHHHHHHHHHHHCCHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCCCCCCCHHH
SRIFANKVIKVYPAFREFYGMEEVIEQVVAYFRHAAQGLEEKKQILYLLGPVGGGKSSIA
HHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHEEEEECCCCCCHHHHH
ERLKQLMERVPFYALKGSPVNESPLGLFDYDEDGPILEEQYGIPRRYLKSILSPWAVKRL
HHHHHHHHHCCEEEECCCCCCCCCCCCCCCCCCCCCHHHHCCCCHHHHHHHHCHHHHHHH
HEYNGDIRRFRVVRRYPSILRQIGIAKTEPGDENNQDISSLVGKVDIRKLEQYAQDDADA
HHHCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCHH
YSYSGGLCLANQGLLEFVEMFKAPIKVLHPLLTATQEGNFKGTEGFGAIPFDGIILAHSN
HCCCCCEEECCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCEEEEECC
ESEWKAFRNNRNNEALLDRIFVVKVPYCLRVSEEIKIYEKLIRNSSLAEAVCAPGTLKMM
CHHHHHHHCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCHHHHHHHCCHHHHHH
AQLSVLTRLHEPENSSLFSKMQVYDGENLKDTDPKAKSYQEYRDYAGVDEGMTGVSTRFA
HHHHHHHHHCCCCCCHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHCCCCCCCCHHHHHHH
FKILSRVFNFDSTEVAANPVHLMYVLEQQIEREQFPPETEQKYLSFVKDLLASRYAEFIG
HHHHHHHHCCCCCHHCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHH
KEIQTAYLESYSEYGQNIFDRYVTYADFWIQDQEFRDHDTGESFDRAALNAELEKIEKPA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHCCCCCCCHHHHHHHHHHHHHHCCCC
GISNPKDFRNEIVNFVLRARAANGGKNPAWVSYEKLRVVIEKKMFSNTEELLPVISFNAK
CCCCHHHHHHHHHHHHHHHHHCCCCCCCCEEHHHHHHHHHHHHHHCCHHHHHHHHCCCCC
GSAEEQRKHEDFVNRMVAKGYTPKQVRLLCDWYLRVRKSS
CCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]