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The map label for this gene is tig

Identifier: 126454578

GI number: 126454578

Start: 2338267

End: 2339616

Strand: Reverse

Name: tig

Synonym: BURPS1106A_2366

Alternate gene names: 126454578

Gene position: 2339616-2338267 (Counterclockwise)

Preceding gene: 126453235

Following gene: 126451473

Centisome position: 58.66

GC content: 64.22

Gene sequence:

>1350_bases
ATGGCTAACGTTGTTGAAAACCTCGGCAAGCTCGAACGCCGTGTGACGATCTCCCTGCCGAAGGATGTCGTGCAGAAGGA
GATCGACGCCCGTATCCAGAAACTCGCGAAGAACGTGCGCATGCCGGGCTTCCGCCCGGGCAAGGTGCCGCTCAAGATGG
TCGCGCAGCAGTACGCGGGCCAGGTCGAGGCAGAGGTGCTGAGCGACAAGATCGGTCAGGAATTCTTCACGATCAGCCGT
GCGGAAAACCTGCGCGTCGCGGGTCAGCCGAGCTTCGCGCCGAAAGAGGACACGCAGCAGGAGAGCGCCTACGCGTTCGA
CGCGACGTTCGAGGTCTATCCGGAAGTGAAGATCGGCGATCTGGCGACGGCTGAAGTCGAGCGCTCGACGACGACGATCG
GCGACGCCGAGATCGACCGCACGCTCGACATCCTGCGCAAGCAGCGCGTGCATTTCCACGCGCGCGGCGAAGGCGGCGAG
CACGGCGACGGCGGCGCGGACACGGCCGCGCAGAACGGCGACCGCGTGACGGTCGATTTCGTCGGCAAGATCGACGGCGT
CGCGTTCCAGGGCGGCACGGCGGAAGACTTCGTGTTCGTGCTCGGCGAAGGGCGGATGCTGCCCGAATTCGAGACGGCGG
CGCTCGGCCTGAAGGCGGGCGAGTCGCGCGAATTCGACCTGAAGTTCCCGGACGATTACCACGGCAAGGATGTGGCGGGC
AAGACCGCGCAGTTCACGGTCACGCTGAAGAAGGTCGAGTGGCCGCATCTGCCCGAGATCGACGCCGATTTCGCGAAGTC
GCTCGGCGTCGAGGACGGCGATCTGACGAAGATGCGCGCCGAGATCAAGGAGAATCTCGAGCGCGAGGCGAAGCGCCGCA
CGCAATCGATCGTGAAGAACCAGGTGATGGACGCGCTCCTGAAGATTTCCGAGCTCGACGTGCCGAAGGCGCTCATCGAG
CAGGATCAGCAGCGCCTCGTCGAGATGGCTCGTCAGGACCTCGCGCAGCGCGGCGTGCCGAACGCGAAGGACGCGCCGAT
TCCGGCCGAGATGTTCGCCGATCAGGCCGAGCGCCGCGTGAAGCTCGGCCTCGTGCTCGCCGAGCTGGTGAAGGCGAACG
GCCTCGAGGCGAAGCCCGAGCAGATTCGCGCGGAAGTCGACGAATTCGCGAAGAGCTACGAGGACCCGAAGGAAGTGGTC
CGCTGGTATTATTCCAATCAGCAGCGCCTTGCCGAAATGGAAGCGTTCGTCGTTGAGAGCAACGTCGTCGATTTCGTGCT
GGGCAAGGCGAAGGTGACGGATAAGGAAGTAAGCTTCGAGGCACTGGCGAGCGCCACGGCGCAAGCATAA

Upstream 100 bases:

>100_bases
CGCGTGAGCGAGGCGGCGGCGCGCGACGGCGCGTCCGCCGCAAGGCTGGCACGGCAAGGAAAAACCGATTCGCTCGAATA
ATTTTAGGACGATTGAAGCC

Downstream 100 bases:

>100_bases
GTGTCGCTCTAGCGGCGTGCCGGCTGTCGGAGCGACGACGGCCCGCACGCCGTTTTTTCATCGGCGCCGCGCACGCGACG
TTCTCCGGCTCGTTTCCTGC

Product: trigger factor

Products: peptidylproline (w =0) [C]

Alternate protein names: TF

Number of amino acids: Translated: 449; Mature: 448

Protein sequence:

>449_residues
MANVVENLGKLERRVTISLPKDVVQKEIDARIQKLAKNVRMPGFRPGKVPLKMVAQQYAGQVEAEVLSDKIGQEFFTISR
AENLRVAGQPSFAPKEDTQQESAYAFDATFEVYPEVKIGDLATAEVERSTTTIGDAEIDRTLDILRKQRVHFHARGEGGE
HGDGGADTAAQNGDRVTVDFVGKIDGVAFQGGTAEDFVFVLGEGRMLPEFETAALGLKAGESREFDLKFPDDYHGKDVAG
KTAQFTVTLKKVEWPHLPEIDADFAKSLGVEDGDLTKMRAEIKENLEREAKRRTQSIVKNQVMDALLKISELDVPKALIE
QDQQRLVEMARQDLAQRGVPNAKDAPIPAEMFADQAERRVKLGLVLAELVKANGLEAKPEQIRAEVDEFAKSYEDPKEVV
RWYYSNQQRLAEMEAFVVESNVVDFVLGKAKVTDKEVSFEALASATAQA

Sequences:

>Translated_449_residues
MANVVENLGKLERRVTISLPKDVVQKEIDARIQKLAKNVRMPGFRPGKVPLKMVAQQYAGQVEAEVLSDKIGQEFFTISR
AENLRVAGQPSFAPKEDTQQESAYAFDATFEVYPEVKIGDLATAEVERSTTTIGDAEIDRTLDILRKQRVHFHARGEGGE
HGDGGADTAAQNGDRVTVDFVGKIDGVAFQGGTAEDFVFVLGEGRMLPEFETAALGLKAGESREFDLKFPDDYHGKDVAG
KTAQFTVTLKKVEWPHLPEIDADFAKSLGVEDGDLTKMRAEIKENLEREAKRRTQSIVKNQVMDALLKISELDVPKALIE
QDQQRLVEMARQDLAQRGVPNAKDAPIPAEMFADQAERRVKLGLVLAELVKANGLEAKPEQIRAEVDEFAKSYEDPKEVV
RWYYSNQQRLAEMEAFVVESNVVDFVLGKAKVTDKEVSFEALASATAQA
>Mature_448_residues
ANVVENLGKLERRVTISLPKDVVQKEIDARIQKLAKNVRMPGFRPGKVPLKMVAQQYAGQVEAEVLSDKIGQEFFTISRA
ENLRVAGQPSFAPKEDTQQESAYAFDATFEVYPEVKIGDLATAEVERSTTTIGDAEIDRTLDILRKQRVHFHARGEGGEH
GDGGADTAAQNGDRVTVDFVGKIDGVAFQGGTAEDFVFVLGEGRMLPEFETAALGLKAGESREFDLKFPDDYHGKDVAGK
TAQFTVTLKKVEWPHLPEIDADFAKSLGVEDGDLTKMRAEIKENLEREAKRRTQSIVKNQVMDALLKISELDVPKALIEQ
DQQRLVEMARQDLAQRGVPNAKDAPIPAEMFADQAERRVKLGLVLAELVKANGLEAKPEQIRAEVDEFAKSYEDPKEVVR
WYYSNQQRLAEMEAFVVESNVVDFVLGKAKVTDKEVSFEALASATAQA

Specific function: Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation

COG id: COG0544

COG function: function code O; FKBP-type peptidyl-prolyl cis-trans isomerase (trigger factor)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PPIase FKBP-type domain

Homologues:

Organism=Escherichia coli, GI1786640, Length=444, Percent_Identity=40.3153153153153, Blast_Score=335, Evalue=3e-93,

Paralogues:

None

Copy number: 1070 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 300 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). 500 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). 340 Molecules/Cell In: Growth-Phase, Mini

Swissprot (AC and ID): TIG_BURM7 (A3MKJ9)

Other databases:

- EMBL:   CP000548
- RefSeq:   YP_001080785.1
- ProteinModelPortal:   A3MKJ9
- SMR:   A3MKJ9
- GeneID:   4892565
- GenomeReviews:   CP000548_GR
- KEGG:   bmn:BMA10247_1233
- TIGR:   BMA10247_1233
- HOGENOM:   HBG635105
- OMA:   RFIPGFE
- ProtClustDB:   PRK01490
- BioCyc:   BMAL320389:BMA10247_1233-MONOMER
- HAMAP:   MF_00303
- InterPro:   IPR001179
- InterPro:   IPR005215
- InterPro:   IPR008880
- InterPro:   IPR008881
- Gene3D:   G3DSA:1.10.3120.10
- Gene3D:   G3DSA:3.30.70.1050
- PANTHER:   PTHR10516
- PIRSF:   PIRSF003095
- TIGRFAMs:   TIGR00115

Pfam domain/function: PF00254 FKBP_C; PF05698 Trigger_C; PF05697 Trigger_N; SSF109998 Trigger_fac_C_bac; SSF102735 Trigger_fac_ribosome-bd_bac

EC number: NA

Molecular weight: Translated: 49739; Mature: 49608

Theoretical pI: Translated: 4.73; Mature: 4.73

Prosite motif: PS50059 FKBP_PPIASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MANVVENLGKLERRVTISLPKDVVQKEIDARIQKLAKNVRMPGFRPGKVPLKMVAQQYAG
CCHHHHHHHHHHHEEEEECCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHCC
QVEAEVLSDKIGQEFFTISRAENLRVAGQPSFAPKEDTQQESAYAFDATFEVYPEVKIGD
HHHHHHHHHHHHHHHHHHHCCCCEEECCCCCCCCCCCCCHHCCEEEECEEEECCCEEECC
LATAEVERSTTTIGDAEIDRTLDILRKQRVHFHARGEGGEHGDGGADTAAQNGDRVTVDF
CHHHHHHHCCCCCCCHHHHHHHHHHHHHHHEEEECCCCCCCCCCCCCHHCCCCCEEEEEE
VGKIDGVAFQGGTAEDFVFVLGEGRMLPEFETAALGLKAGESREFDLKFPDDYHGKDVAG
EECCCCEEECCCCCCCEEEEEECCCCCCCHHHHHHCCCCCCCCCEECCCCCCCCCCCCCC
KTAQFTVTLKKVEWPHLPEIDADFAKSLGVEDGDLTKMRAEIKENLEREAKRRTQSIVKN
CCEEEEEEEEECCCCCCCCCCHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
QVMDALLKISELDVPKALIEQDQQRLVEMARQDLAQRGVPNAKDAPIPAEMFADQAERRV
HHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHH
KLGLVLAELVKANGLEAKPEQIRAEVDEFAKSYEDPKEVVRWYYSNQQRLAEMEAFVVES
HHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHCCHHHHHHHHHHHHHC
NVVDFVLGKAKVTDKEVSFEALASATAQA
CHHHHHHCCCCCCCHHHHHHHHHHHHCCC
>Mature Secondary Structure 
ANVVENLGKLERRVTISLPKDVVQKEIDARIQKLAKNVRMPGFRPGKVPLKMVAQQYAG
CHHHHHHHHHHHEEEEECCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHCC
QVEAEVLSDKIGQEFFTISRAENLRVAGQPSFAPKEDTQQESAYAFDATFEVYPEVKIGD
HHHHHHHHHHHHHHHHHHHCCCCEEECCCCCCCCCCCCCHHCCEEEECEEEECCCEEECC
LATAEVERSTTTIGDAEIDRTLDILRKQRVHFHARGEGGEHGDGGADTAAQNGDRVTVDF
CHHHHHHHCCCCCCCHHHHHHHHHHHHHHHEEEECCCCCCCCCCCCCHHCCCCCEEEEEE
VGKIDGVAFQGGTAEDFVFVLGEGRMLPEFETAALGLKAGESREFDLKFPDDYHGKDVAG
EECCCCEEECCCCCCCEEEEEECCCCCCCHHHHHHCCCCCCCCCEECCCCCCCCCCCCCC
KTAQFTVTLKKVEWPHLPEIDADFAKSLGVEDGDLTKMRAEIKENLEREAKRRTQSIVKN
CCEEEEEEEEECCCCCCCCCCHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
QVMDALLKISELDVPKALIEQDQQRLVEMARQDLAQRGVPNAKDAPIPAEMFADQAERRV
HHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHH
KLGLVLAELVKANGLEAKPEQIRAEVDEFAKSYEDPKEVVRWYYSNQQRLAEMEAFVVES
HHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHCCHHHHHHHHHHHHHC
NVVDFVLGKAKVTDKEVSFEALASATAQA
CHHHHHHCCCCCCCHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: peptidylproline (w =180) [C]

Specific reaction: peptidylproline (w =180) = peptidylproline (w =0) [C]

General reaction: Isomerases; cis-trans-Isomerases [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA