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The map label for this gene is mraW [H]

Identifier: 126454576

GI number: 126454576

Start: 3464130

End: 3465071

Strand: Reverse

Name: mraW [H]

Synonym: BURPS1106A_3558

Alternate gene names: 126454576

Gene position: 3465071-3464130 (Counterclockwise)

Preceding gene: 126455248

Following gene: 126454651

Centisome position: 86.88

GC content: 65.71

Gene sequence:

>942_bases
ATGGGAAACGAATTCCAGCATCGCACGGTGCTGTTGGATGAAGCGGTCGATGCGCTCGTGACGCGGCCCGACGGCGTGTA
TGTCGACGGCACGTTCGGGCGCGGCGGCCATAGCCGCGCGGTGCTCGCGCGCCTGGGCGACGCGGGACGGCTGATCGCGT
TCGACAAGGATCCGCGCGCGATCGAGACGGCCGAGAGCATCGAGGATGCGCGGTTCGAGATCGTCCATGACAGTTTTGCG
GCGATGAAGGGCGCACTCGATGCGCGCGGAGTAGGGCGGGTGTCGGGCGTGCTGCTGGATCTGGGCGTGTCTTCGCCGCA
GGTGGACGATCCGGCGCGCGGCTTCAGCTTCCGCGCGAACGGTCCGCTCGACATGCGGATGGACCCGACGCGTGGCGAAT
CGGCGGCCGAGTGGCTCGCACGGGCGTCGGTGCAGGAATTGACGGAGGTGATACGAGATTATGGGGAAGAACGGTTTGCT
TTTCAGATTGCAAAGGCGATTGTTGCTCGCCGGGCAGAGTCCGACCGTCTCGGGCCTCTCGACAGCACGGGCGAGCTTGC
CCAAATCGTGGGTCACGTCGTCAAGACCCGTGAGAAGGGTAAGGATCCGGCAACCCGCACCTTTCAGGCTATACGGATTC
ACGTCAATCAAGAGCTTGCGGACCTGCAAGTCGTTCTAGAGGCAGCACTGTCGTTGTTGGAGCAAGGGGGCCGGCTGGTG
GTCATCAGCTTTCATTCGCTCGAGGACCGGATCGTCAAGCGATTCCTGCAGGCGCACGCAAGCGCGCCTGCGGTCGACCG
CCGCCTGCCGATCCGCGCGGCCGACCTGCCCAGCCCGCCGCTCAAGCTGCTCGGCCGGATGTTCCCGAACGACGCGGAAG
TCGCGGCCAATCCGCGTGCCCGTTCGGCGGTGATGCGCATCGCGGAGCGCGTCGCGCCATGA

Upstream 100 bases:

>100_bases
CGCAGACCTACACCGCGAAGGAGCAGGCGGCGATGGCGCAGGGCATGCCCGAAGCGCTGAAGAATTTCACGTTCTGATTG
CGGTGAGGAAGACGCCCGCG

Downstream 100 bases:

>100_bases
GCCGCCTCAATATCTTCCTGCTGATCATTGTGATGGGATGCGCGCTGTCGGTCGTCAATTCGACGAACCAGCAGCGGCAG
ATTTTCATCCAGTTGCAGCG

Product: S-adenosyl-methyltransferase MraW

Products: NA

Alternate protein names: 16S rRNA m(4)C1402 methyltransferase; rRNA (cytosine-N(4)-)-methyltransferase RsmH [H]

Number of amino acids: Translated: 313; Mature: 312

Protein sequence:

>313_residues
MGNEFQHRTVLLDEAVDALVTRPDGVYVDGTFGRGGHSRAVLARLGDAGRLIAFDKDPRAIETAESIEDARFEIVHDSFA
AMKGALDARGVGRVSGVLLDLGVSSPQVDDPARGFSFRANGPLDMRMDPTRGESAAEWLARASVQELTEVIRDYGEERFA
FQIAKAIVARRAESDRLGPLDSTGELAQIVGHVVKTREKGKDPATRTFQAIRIHVNQELADLQVVLEAALSLLEQGGRLV
VISFHSLEDRIVKRFLQAHASAPAVDRRLPIRAADLPSPPLKLLGRMFPNDAEVAANPRARSAVMRIAERVAP

Sequences:

>Translated_313_residues
MGNEFQHRTVLLDEAVDALVTRPDGVYVDGTFGRGGHSRAVLARLGDAGRLIAFDKDPRAIETAESIEDARFEIVHDSFA
AMKGALDARGVGRVSGVLLDLGVSSPQVDDPARGFSFRANGPLDMRMDPTRGESAAEWLARASVQELTEVIRDYGEERFA
FQIAKAIVARRAESDRLGPLDSTGELAQIVGHVVKTREKGKDPATRTFQAIRIHVNQELADLQVVLEAALSLLEQGGRLV
VISFHSLEDRIVKRFLQAHASAPAVDRRLPIRAADLPSPPLKLLGRMFPNDAEVAANPRARSAVMRIAERVAP
>Mature_312_residues
GNEFQHRTVLLDEAVDALVTRPDGVYVDGTFGRGGHSRAVLARLGDAGRLIAFDKDPRAIETAESIEDARFEIVHDSFAA
MKGALDARGVGRVSGVLLDLGVSSPQVDDPARGFSFRANGPLDMRMDPTRGESAAEWLARASVQELTEVIRDYGEERFAF
QIAKAIVARRAESDRLGPLDSTGELAQIVGHVVKTREKGKDPATRTFQAIRIHVNQELADLQVVLEAALSLLEQGGRLVV
ISFHSLEDRIVKRFLQAHASAPAVDRRLPIRAADLPSPPLKLLGRMFPNDAEVAANPRARSAVMRIAERVAP

Specific function: Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA [H]

COG id: COG0275

COG function: function code M; Predicted S-adenosylmethionine-dependent methyltransferase involved in cell envelope biogenesis

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the methyltransferase superfamily. RsmH family [H]

Homologues:

Organism=Homo sapiens, GI165377209, Length=338, Percent_Identity=38.4615384615385, Blast_Score=181, Evalue=5e-46,
Organism=Homo sapiens, GI165377202, Length=198, Percent_Identity=38.8888888888889, Blast_Score=120, Evalue=2e-27,
Organism=Escherichia coli, GI1786270, Length=315, Percent_Identity=53.6507936507937, Blast_Score=335, Evalue=2e-93,
Organism=Drosophila melanogaster, GI62472493, Length=331, Percent_Identity=36.5558912386707, Blast_Score=168, Evalue=4e-42,
Organism=Drosophila melanogaster, GI28571637, Length=331, Percent_Identity=36.5558912386707, Blast_Score=168, Evalue=4e-42,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002903 [H]

Pfam domain/function: PF01795 Methyltransf_5 [H]

EC number: NA

Molecular weight: Translated: 34078; Mature: 33947

Theoretical pI: Translated: 6.65; Mature: 6.65

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGNEFQHRTVLLDEAVDALVTRPDGVYVDGTFGRGGHSRAVLARLGDAGRLIAFDKDPRA
CCCCCCHHHHHHHHHHHHHHCCCCCEEEECCCCCCCCHHHHHHHCCCCCCEEEECCCCCH
IETAESIEDARFEIVHDSFAAMKGALDARGVGRVSGVLLDLGVSSPQVDDPARGFSFRAN
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHEECCCCCCCCCCCCCCCEEECC
GPLDMRMDPTRGESAAEWLARASVQELTEVIRDYGEERFAFQIAKAIVARRAESDRLGPL
CCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHCCCCCCCCC
DSTGELAQIVGHVVKTREKGKDPATRTFQAIRIHVNQELADLQVVLEAALSLLEQGGRLV
CCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHEEECCHHHHHHHHHHHHHHHHHHCCCCEE
VISFHSLEDRIVKRFLQAHASAPAVDRRLPIRAADLPSPPLKLLGRMFPNDAEVAANPRA
EEEECCHHHHHHHHHHHHHCCCCCCCCCCCCEECCCCCCHHHHHHHHCCCCCCCCCCCHH
RSAVMRIAERVAP
HHHHHHHHHHHCC
>Mature Secondary Structure 
GNEFQHRTVLLDEAVDALVTRPDGVYVDGTFGRGGHSRAVLARLGDAGRLIAFDKDPRA
CCCCCHHHHHHHHHHHHHHCCCCCEEEECCCCCCCCHHHHHHHCCCCCCEEEECCCCCH
IETAESIEDARFEIVHDSFAAMKGALDARGVGRVSGVLLDLGVSSPQVDDPARGFSFRAN
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHEECCCCCCCCCCCCCCCEEECC
GPLDMRMDPTRGESAAEWLARASVQELTEVIRDYGEERFAFQIAKAIVARRAESDRLGPL
CCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHCCCCCCCCC
DSTGELAQIVGHVVKTREKGKDPATRTFQAIRIHVNQELADLQVVLEAALSLLEQGGRLV
CCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHEEECCHHHHHHHHHHHHHHHHHHCCCCEE
VISFHSLEDRIVKRFLQAHASAPAVDRRLPIRAADLPSPPLKLLGRMFPNDAEVAANPRA
EEEECCHHHHHHHHHHHHHCCCCCCCCCCCCEECCCCCCHHHHHHHHCCCCCCCCCCCHH
RSAVMRIAERVAP
HHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA