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The map label for this gene is zraR [H]

Identifier: 126454481

GI number: 126454481

Start: 622265

End: 623653

Strand: Direct

Name: zraR [H]

Synonym: BURPS1106A_0650

Alternate gene names: 126454481

Gene position: 622265-623653 (Clockwise)

Preceding gene: 126451645

Following gene: 126452554

Centisome position: 15.6

GC content: 68.68

Gene sequence:

>1389_bases
ATGACGACTAGCGCGATCATCGGGGGGCCCTCCCGGGGATCGATCCGACAGCGACCGTTGATTTACTGGACGCATCAGCC
TTCGACGCTGCTGCGCAAGGAACTCGCGCGCCGCGACTGGAAGATCTCCGTCGTCACGAGCGCGAACCAGGTGCGCACGA
CGGCGGGCGAGGTCACGGGCGGCATTCTCGATCTGAGCGCCGTGTCGATCGACGAGATGAACGCGGTGGCGGCCGTATGC
GCGTCGCTGCGCAACGTCGCGTGGGTCGCGCTCGTCGAAGCGCAGCAGGCGAACGTGCCGAACGTGCGCACGCTGCTGCG
CGATTACTGCTTCGACTACATCACGCTGCCCGCGTCGCATCAGCGGATCGCGGATGCGGTGGGTCACGCGTACGGGATGG
AATGCCTGTTCGCGCCGAGCACGGCGCCGATCGCGTCCGCCGATCAGGGGATGATCGGCACGTGCGACGCGATGCTGCAA
CTGTTCGACACGGTGCGCCGGATCGCGCGCACCGACGCGCCCGTGCTCGTGTCCGGCGAGACCGGCACCGGCAAGGAACT
CACCGCGGCCGCGATCCATCAGCATTCCGCGCGCCGCGCGGGCCCGTTCGTCGCGGTCAATTGCGGCGCGATTCCGCCGC
ATCTGCTGCAATCCGAACTATTCGGCTACGAGCGCGGCGCATTCACCGGCGCGAGCACGCGCAAGATCGGCCATGTCGAA
TCGGCGAACGGCGGCACGCTGCTGCTCGACGAAATCGGCGATTTGCCGCTCGAAAGCCAGGCGAGCCTGCTGCGCTTCCT
GCAGGAGCGCACGATTCATCGGCTGGGCGGCAGCGAGCCGGTGCCCGTCGACGTGCGCATCGTATCGGCGACGCACGTCG
ATCTGCGCGGCGCGATGAACGAAGGGCGTTTCCGCGCGGACCTGTATCACCGGCTGTGCGTGCTGCGCGTCGACCAGCCG
CCGCTGCGCGCGCGAGGCAAGGACATCGAACTGCTCGCGCGGCACATGCTCGAGCGCTTTCGCGCCGACGCGCGGCACCG
CGTGCGTGGCTTCTCGACCGATGCGATCTCCGCGCTCTACAAGCACGATTGGCCGGGCAACGTGCGCGAGCTCATCAACC
GCGTGCGCCGCGCGCTCGTGATGGCGGAAGGGCGGCTCATCACCGCGCACGATCTCGAGCTCGACCATTGCACCGAGGTC
GCGCCGCTGTCGGTCGCCGCGATCCGCAAATCGATCGAGCGGGAAGTGATCGAGCTCGCGCTGTTGCGCAATCGCGGGCG
CCTCGCGGGCACCGCGCGCGAGCTCGGCATCTCGCGCGCGACGCTGTATCGGTGGATGGAGGCGTACGGCATCGAGCGCC
CGCGCAGCGCCGCGTCGTCCGCCAATTGA

Upstream 100 bases:

>100_bases
TCCCATCTCGCGCTGCGTCGCCGGTAGGCAGACGATCGTCGGCTCTTGCCCGTCCACGAATTCGTCGAGTCACACAGTCA
GTTCATGATCGGAGGCGCCA

Downstream 100 bases:

>100_bases
AACGAAACGCCGGCGCGCCGCGGCGAACGCGCCGCGCCGGCGTGCGCGCCGCCGTCAGGAGGACGCGGCCGCGTCGGCGG
ACGCCGCATGCGCCGCGCCG

Product: sigma-54 dependent trancsriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 462; Mature: 461

Protein sequence:

>462_residues
MTTSAIIGGPSRGSIRQRPLIYWTHQPSTLLRKELARRDWKISVVTSANQVRTTAGEVTGGILDLSAVSIDEMNAVAAVC
ASLRNVAWVALVEAQQANVPNVRTLLRDYCFDYITLPASHQRIADAVGHAYGMECLFAPSTAPIASADQGMIGTCDAMLQ
LFDTVRRIARTDAPVLVSGETGTGKELTAAAIHQHSARRAGPFVAVNCGAIPPHLLQSELFGYERGAFTGASTRKIGHVE
SANGGTLLLDEIGDLPLESQASLLRFLQERTIHRLGGSEPVPVDVRIVSATHVDLRGAMNEGRFRADLYHRLCVLRVDQP
PLRARGKDIELLARHMLERFRADARHRVRGFSTDAISALYKHDWPGNVRELINRVRRALVMAEGRLITAHDLELDHCTEV
APLSVAAIRKSIEREVIELALLRNRGRLAGTARELGISRATLYRWMEAYGIERPRSAASSAN

Sequences:

>Translated_462_residues
MTTSAIIGGPSRGSIRQRPLIYWTHQPSTLLRKELARRDWKISVVTSANQVRTTAGEVTGGILDLSAVSIDEMNAVAAVC
ASLRNVAWVALVEAQQANVPNVRTLLRDYCFDYITLPASHQRIADAVGHAYGMECLFAPSTAPIASADQGMIGTCDAMLQ
LFDTVRRIARTDAPVLVSGETGTGKELTAAAIHQHSARRAGPFVAVNCGAIPPHLLQSELFGYERGAFTGASTRKIGHVE
SANGGTLLLDEIGDLPLESQASLLRFLQERTIHRLGGSEPVPVDVRIVSATHVDLRGAMNEGRFRADLYHRLCVLRVDQP
PLRARGKDIELLARHMLERFRADARHRVRGFSTDAISALYKHDWPGNVRELINRVRRALVMAEGRLITAHDLELDHCTEV
APLSVAAIRKSIEREVIELALLRNRGRLAGTARELGISRATLYRWMEAYGIERPRSAASSAN
>Mature_461_residues
TTSAIIGGPSRGSIRQRPLIYWTHQPSTLLRKELARRDWKISVVTSANQVRTTAGEVTGGILDLSAVSIDEMNAVAAVCA
SLRNVAWVALVEAQQANVPNVRTLLRDYCFDYITLPASHQRIADAVGHAYGMECLFAPSTAPIASADQGMIGTCDAMLQL
FDTVRRIARTDAPVLVSGETGTGKELTAAAIHQHSARRAGPFVAVNCGAIPPHLLQSELFGYERGAFTGASTRKIGHVES
ANGGTLLLDEIGDLPLESQASLLRFLQERTIHRLGGSEPVPVDVRIVSATHVDLRGAMNEGRFRADLYHRLCVLRVDQPP
LRARGKDIELLARHMLERFRADARHRVRGFSTDAISALYKHDWPGNVRELINRVRRALVMAEGRLITAHDLELDHCTEVA
PLSVAAIRKSIEREVIELALLRNRGRLAGTARELGISRATLYRWMEAYGIERPRSAASSAN

Specific function: Member of the two-component regulatory system zraS/zraR. When activated by zraS it acts in conjunction with sigma-54 to regulate the expression of zraP. Positively autoregulates the expression of the zraSR operon [H]

COG id: COG2204

COG function: function code T; Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 sigma-54 factor interaction domain [H]

Homologues:

Organism=Escherichia coli, GI1790437, Length=411, Percent_Identity=39.1727493917275, Blast_Score=269, Evalue=2e-73,
Organism=Escherichia coli, GI1788550, Length=363, Percent_Identity=42.4242424242424, Blast_Score=258, Evalue=5e-70,
Organism=Escherichia coli, GI1790299, Length=375, Percent_Identity=38.9333333333333, Blast_Score=243, Evalue=2e-65,
Organism=Escherichia coli, GI1788905, Length=396, Percent_Identity=36.6161616161616, Blast_Score=242, Evalue=4e-65,
Organism=Escherichia coli, GI87082117, Length=319, Percent_Identity=43.8871473354232, Blast_Score=241, Evalue=6e-65,
Organism=Escherichia coli, GI1789233, Length=331, Percent_Identity=43.202416918429, Blast_Score=239, Evalue=3e-64,
Organism=Escherichia coli, GI1789087, Length=308, Percent_Identity=40.2597402597403, Blast_Score=223, Evalue=1e-59,
Organism=Escherichia coli, GI1786524, Length=325, Percent_Identity=41.5384615384615, Blast_Score=219, Evalue=2e-58,
Organism=Escherichia coli, GI87082152, Length=317, Percent_Identity=42.2712933753943, Blast_Score=210, Evalue=1e-55,
Organism=Escherichia coli, GI87081872, Length=312, Percent_Identity=37.1794871794872, Blast_Score=201, Evalue=7e-53,
Organism=Escherichia coli, GI1787583, Length=320, Percent_Identity=36.25, Blast_Score=184, Evalue=8e-48,
Organism=Escherichia coli, GI87081858, Length=294, Percent_Identity=34.0136054421769, Blast_Score=150, Evalue=2e-37,
Organism=Escherichia coli, GI1789828, Length=243, Percent_Identity=35.8024691358025, Blast_Score=135, Evalue=8e-33,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR011006
- InterPro:   IPR020441
- InterPro:   IPR009057
- InterPro:   IPR002197
- InterPro:   IPR002078
- InterPro:   IPR001789 [H]

Pfam domain/function: PF02954 HTH_8; PF00072 Response_reg; PF00158 Sigma54_activat [H]

EC number: NA

Molecular weight: Translated: 50644; Mature: 50512

Theoretical pI: Translated: 9.24; Mature: 9.24

Prosite motif: PS00676 SIGMA54_INTERACT_2 ; PS00688 SIGMA54_INTERACT_3 ; PS50045 SIGMA54_INTERACT_4

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTSAIIGGPSRGSIRQRPLIYWTHQPSTLLRKELARRDWKISVVTSANQVRTTAGEVTG
CCCCCEECCCCCCCCCCCCEEEEECCCHHHHHHHHHHCCCEEEEEECCCHHHHHHHHHCC
GILDLSAVSIDEMNAVAAVCASLRNVAWVALVEAQQANVPNVRTLLRDYCFDYITLPASH
CEEEEEECCHHHHHHHHHHHHHHHHHHEEEEEEHHCCCCCHHHHHHHHHHHHHEECCCCH
QRIADAVGHAYGMECLFAPSTAPIASADQGMIGTCDAMLQLFDTVRRIARTDAPVLVSGE
HHHHHHHHHHHCCEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCEEEECC
TGTGKELTAAAIHQHSARRAGPFVAVNCGAIPPHLLQSELFGYERGAFTGASTRKIGHVE
CCCCCHHHHHHHHHHHHHHCCCEEEEECCCCCHHHHHHHHCCCCCCCCCCCCCCCCCCEE
SANGGTLLLDEIGDLPLESQASLLRFLQERTIHRLGGSEPVPVDVRIVSATHVDLRGAMN
CCCCCEEEEECCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCEEEEEEEEEEEHHHCCCC
EGRFRADLYHRLCVLRVDQPPLRARGKDIELLARHMLERFRADARHRVRGFSTDAISALY
CCCHHHHHHHCEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHH
KHDWPGNVRELINRVRRALVMAEGRLITAHDLELDHCTEVAPLSVAAIRKSIEREVIELA
HCCCCCHHHHHHHHHHHHHHHHCCCEEEEECCCHHHHCCCCHHHHHHHHHHHHHHHHHHH
LLRNRGRLAGTARELGISRATLYRWMEAYGIERPRSAASSAN
HHHCCCCCCCHHHHHCCHHHHHHHHHHHHCCCCCCCCCCCCC
>Mature Secondary Structure 
TTSAIIGGPSRGSIRQRPLIYWTHQPSTLLRKELARRDWKISVVTSANQVRTTAGEVTG
CCCCEECCCCCCCCCCCCEEEEECCCHHHHHHHHHHCCCEEEEEECCCHHHHHHHHHCC
GILDLSAVSIDEMNAVAAVCASLRNVAWVALVEAQQANVPNVRTLLRDYCFDYITLPASH
CEEEEEECCHHHHHHHHHHHHHHHHHHEEEEEEHHCCCCCHHHHHHHHHHHHHEECCCCH
QRIADAVGHAYGMECLFAPSTAPIASADQGMIGTCDAMLQLFDTVRRIARTDAPVLVSGE
HHHHHHHHHHHCCEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCEEEECC
TGTGKELTAAAIHQHSARRAGPFVAVNCGAIPPHLLQSELFGYERGAFTGASTRKIGHVE
CCCCCHHHHHHHHHHHHHHCCCEEEEECCCCCHHHHHHHHCCCCCCCCCCCCCCCCCCEE
SANGGTLLLDEIGDLPLESQASLLRFLQERTIHRLGGSEPVPVDVRIVSATHVDLRGAMN
CCCCCEEEEECCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCEEEEEEEEEEEHHHCCCC
EGRFRADLYHRLCVLRVDQPPLRARGKDIELLARHMLERFRADARHRVRGFSTDAISALY
CCCHHHHHHHCEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHH
KHDWPGNVRELINRVRRALVMAEGRLITAHDLELDHCTEVAPLSVAAIRKSIEREVIELA
HCCCCCHHHHHHHHHHHHHHHHCCCEEEEECCCHHHHCCCCHHHHHHHHHHHHHHHHHHH
LLRNRGRLAGTARELGISRATLYRWMEAYGIERPRSAASSAN
HHHCCCCCCCHHHHHCCHHHHHHHHHHHHCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]