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The map label for this gene is hpmB [H]

Identifier: 126454471

GI number: 126454471

Start: 3774386

End: 3776071

Strand: Reverse

Name: hpmB [H]

Synonym: BURPS1106A_3879

Alternate gene names: 126454471

Gene position: 3776071-3774386 (Counterclockwise)

Preceding gene: 126454501

Following gene: 126453330

Centisome position: 94.68

GC content: 60.56

Gene sequence:

>1686_bases
ATGGCAGTGTCGGCGCAAGAAGCTCCCCGTCTCATCATTCCGGGCAACGACCAGCAAACCCGACAGCAGGAAGAGGCACG
AGAGCGTGAACGGGTAGTCTCCGCGCCCGGGGTGCGATCGGAAGTGATGCGAAGTGCTGAGTATCCAACGCTGCCTTCTG
AAACGCCTTGCTTTCGGATCAAGCGTTTCGTACTCGAGGTACCCGATGCGCTGCCTGCTTCCCTGAAATCGCAAGGCGCA
TCGGCATTGCCGATGGATCGCTTCGCATTCGCGCGTGAATGGCTTGGGCACTACGCGGGCGCGTGCGTTGGCAAACAGGG
TCTCGATTTGCTCGTCAAAGGCTTGTCGCAAGCGATCCTGGCGCGCGGTTATGTGACGACGCGCGTGCTGCTGCCCGAAC
AGGATCTGTCGACTGGCACCCTCAAGTTTTCACTGGTTCCTGGCGTAATCCGCCATGTGCATTTTGCCGACGAGAAGCTC
CGCGGCACGTGGAAAACCGCCTTTCCGACTCGCGACGGCGAACTACTGAACCTGCGCGACCTCGAACAAGGCCTCGAACA
GATGAAGCGCGTGACGAGCCAGGACGTATCGATGCAGATCGTCCCAGCCGACGTTCCCGGCGAAAGCGACGTGGTGCTCG
ACGTAAAGCGCACTAAGCCCTGGACGGTCGTCGCTTCGATCGACAACTCGGGCACGCGCGCTACGGGCCGCCTTCAGGGG
AACTTGTCGCTCGGTATCGACAATCCCCTTGGCCTGAACGATATCTTCAACATTGGCGTGAGCCAGGATCTGGAATTCGG
CGACAAGCGACTCGGCTCGCATGGCTGGAACGGTTTCTACTCGATCCCGTGGGGCTATTGGACCGCCACACTATCGGCGT
ACACCAACACGTACTACCAGCAAATCGCTGGCGTGAATCAAACGTTCATCGCGAGCGGCAATTCAAAGACAGTTGATTTC
AAGCTGAGCCGCGTGCTGTCGCGTAGCCAGAACGACGTGTTCGGTGCTCAGTTTCGCTTGTCGCGCCGGTTTGGGCAAAG
CTTCATCGAGGACACGGAAATTCCGCAGCAGCGTCGCAACAACACGTTCGTCGAGTTCGGCCTGACCGATCGCCATTATT
TTGGCAATGCGCAGTTCGACGGGATGCTCGCTTACCGGCAGGGTATCGGCGCGTTCGGCGCGCAGGACGACAGCCTCGCG
GCAGACGGCGGTCCGACCTACCGCTACAAGATGGCCGTGCTCGATGCGAATCTGTCAGTGCCGTTCGCAATCGCGCAGCA
GCCGTTCCGCTACGTGACGACGTTCCACGGACAATACACGGGCAACACGCTGTACTACATCGACGACCTGACGATCGGCA
GTCGTTACACAGTACGTGGATTCGACGGAGAGACGATGCTGGCCGCCTCCCGCGGCCTCTATTGGCGCAACGAACTGCAG
GCGCCGATCGGCCAAACCGGGCAGGCGATATACGCGGGCATCGACTACGGCCGCGTGTGGGGCCCGCAACCCGTCACCCT
CGTCGGCACGCAGCTGGCGGGCGCCGTGATAGGCGTAAAGGGCAGTGTCGCGACTCGATTGGGCGCCTATGGTTACGACC
TGTTTGCCGGAACGCCGATCTACAAGCCGTCCGGGTTTCCTACGGCACGCGTGACGGTTGGTTTTCAGGTCACCGCACAG
TTCTGA

Upstream 100 bases:

>100_bases
GGGACACCTTGCACCTAAGCCTTAAGATCGAACTAACAACACCACATCTATGACAATCCGTACCCCGGCCGTCCTGCTGT
CGGCTGCATGGCTGATACCA

Downstream 100 bases:

>100_bases
TGAAGCAAGCCCACTCCGTTACTCGGCTTGCCGTCTTCGGTGTCTGAGCATTTGGCGATCAACGGGCTACGCGAGGGAGT
TATTTCGAATGGTGAAAGTG

Product: outer membrane hemolysin activator protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 561; Mature: 560

Protein sequence:

>561_residues
MAVSAQEAPRLIIPGNDQQTRQQEEARERERVVSAPGVRSEVMRSAEYPTLPSETPCFRIKRFVLEVPDALPASLKSQGA
SALPMDRFAFAREWLGHYAGACVGKQGLDLLVKGLSQAILARGYVTTRVLLPEQDLSTGTLKFSLVPGVIRHVHFADEKL
RGTWKTAFPTRDGELLNLRDLEQGLEQMKRVTSQDVSMQIVPADVPGESDVVLDVKRTKPWTVVASIDNSGTRATGRLQG
NLSLGIDNPLGLNDIFNIGVSQDLEFGDKRLGSHGWNGFYSIPWGYWTATLSAYTNTYYQQIAGVNQTFIASGNSKTVDF
KLSRVLSRSQNDVFGAQFRLSRRFGQSFIEDTEIPQQRRNNTFVEFGLTDRHYFGNAQFDGMLAYRQGIGAFGAQDDSLA
ADGGPTYRYKMAVLDANLSVPFAIAQQPFRYVTTFHGQYTGNTLYYIDDLTIGSRYTVRGFDGETMLAASRGLYWRNELQ
APIGQTGQAIYAGIDYGRVWGPQPVTLVGTQLAGAVIGVKGSVATRLGAYGYDLFAGTPIYKPSGFPTARVTVGFQVTAQ
F

Sequences:

>Translated_561_residues
MAVSAQEAPRLIIPGNDQQTRQQEEARERERVVSAPGVRSEVMRSAEYPTLPSETPCFRIKRFVLEVPDALPASLKSQGA
SALPMDRFAFAREWLGHYAGACVGKQGLDLLVKGLSQAILARGYVTTRVLLPEQDLSTGTLKFSLVPGVIRHVHFADEKL
RGTWKTAFPTRDGELLNLRDLEQGLEQMKRVTSQDVSMQIVPADVPGESDVVLDVKRTKPWTVVASIDNSGTRATGRLQG
NLSLGIDNPLGLNDIFNIGVSQDLEFGDKRLGSHGWNGFYSIPWGYWTATLSAYTNTYYQQIAGVNQTFIASGNSKTVDF
KLSRVLSRSQNDVFGAQFRLSRRFGQSFIEDTEIPQQRRNNTFVEFGLTDRHYFGNAQFDGMLAYRQGIGAFGAQDDSLA
ADGGPTYRYKMAVLDANLSVPFAIAQQPFRYVTTFHGQYTGNTLYYIDDLTIGSRYTVRGFDGETMLAASRGLYWRNELQ
APIGQTGQAIYAGIDYGRVWGPQPVTLVGTQLAGAVIGVKGSVATRLGAYGYDLFAGTPIYKPSGFPTARVTVGFQVTAQ
F
>Mature_560_residues
AVSAQEAPRLIIPGNDQQTRQQEEARERERVVSAPGVRSEVMRSAEYPTLPSETPCFRIKRFVLEVPDALPASLKSQGAS
ALPMDRFAFAREWLGHYAGACVGKQGLDLLVKGLSQAILARGYVTTRVLLPEQDLSTGTLKFSLVPGVIRHVHFADEKLR
GTWKTAFPTRDGELLNLRDLEQGLEQMKRVTSQDVSMQIVPADVPGESDVVLDVKRTKPWTVVASIDNSGTRATGRLQGN
LSLGIDNPLGLNDIFNIGVSQDLEFGDKRLGSHGWNGFYSIPWGYWTATLSAYTNTYYQQIAGVNQTFIASGNSKTVDFK
LSRVLSRSQNDVFGAQFRLSRRFGQSFIEDTEIPQQRRNNTFVEFGLTDRHYFGNAQFDGMLAYRQGIGAFGAQDDSLAA
DGGPTYRYKMAVLDANLSVPFAIAQQPFRYVTTFHGQYTGNTLYYIDDLTIGSRYTVRGFDGETMLAASRGLYWRNELQA
PIGQTGQAIYAGIDYGRVWGPQPVTLVGTQLAGAVIGVKGSVATRLGAYGYDLFAGTPIYKPSGFPTARVTVGFQVTAQF

Specific function: Probable member of a two partner secretion pathway (TPS) in which it mediates the secretion of hemolysin [H]

COG id: COG2831

COG function: function code U; Hemolysin activation/secretion protein

Gene ontology:

Cell location: Cell outer membrane [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the tpsB (TC 1.B.20) family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005565
- InterPro:   IPR013686 [H]

Pfam domain/function: PF08479 POTRA_2; PF03865 ShlB [H]

EC number: NA

Molecular weight: Translated: 61753; Mature: 61622

Theoretical pI: Translated: 8.76; Mature: 8.76

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAVSAQEAPRLIIPGNDQQTRQQEEARERERVVSAPGVRSEVMRSAEYPTLPSETPCFRI
CCCCCCCCCEEEECCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCCCCCCHHHHH
KRFVLEVPDALPASLKSQGASALPMDRFAFAREWLGHYAGACVGKQGLDLLVKGLSQAIL
HHHHHHCCCCCCHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHH
ARGYVTTRVLLPEQDLSTGTLKFSLVPGVIRHVHFADEKLRGTWKTAFPTRDGELLNLRD
HCCCEEEEEEECCCCCCCCEEEEEEHHHHHHHHHHCCHHHCCCEEECCCCCCCCEECHHH
LEQGLEQMKRVTSQDVSMQIVPADVPGESDVVLDVKRTKPWTVVASIDNSGTRATGRLQG
HHHHHHHHHHHHCCCCEEEEEECCCCCCCCEEEEEECCCCEEEEEEECCCCCEEEEEEEE
NLSLGIDNPLGLNDIFNIGVSQDLEFGDKRLGSHGWNGFYSIPWGYWTATLSAYTNTYYQ
EEEECCCCCCCCHHHHHCCCCCCCCHHHHHCCCCCCCCEEECCCHHHHHHHHHHHHHHHH
QIAGVNQTFIASGNSKTVDFKLSRVLSRSQNDVFGAQFRLSRRFGQSFIEDTEIPQQRRN
HHCCCCEEEEECCCCCEEEHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHCCCCCHHHCC
NTFVEFGLTDRHYFGNAQFDGMLAYRQGIGAFGAQDDSLAADGGPTYRYKMAVLDANLSV
CCEEEECCCCCEEECCCCCCCHHHHHHCCCCCCCCCCCCCCCCCCCEEEEEEEEECCCCC
PFAIAQQPFRYVTTFHGQYTGNTLYYIDDLTIGSRYTVRGFDGETMLAASRGLYWRNELQ
CHHHHCCCCEEEEEECCEECCCEEEEEEEEEECCEEEEECCCCCEEEEHHCCCEEHHHCC
APIGQTGQAIYAGIDYGRVWGPQPVTLVGTQLAGAVIGVKGSVATRLGAYGYDLFAGTPI
CCCCCCCCEEEEECCCCCCCCCCCEEEECHHHHCEEEECCCHHHHHHCCCCCHHHCCCCC
YKPSGFPTARVTVGFQVTAQF
CCCCCCCEEEEEEEEEEEEEC
>Mature Secondary Structure 
AVSAQEAPRLIIPGNDQQTRQQEEARERERVVSAPGVRSEVMRSAEYPTLPSETPCFRI
CCCCCCCCEEEECCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCCCCCCHHHHH
KRFVLEVPDALPASLKSQGASALPMDRFAFAREWLGHYAGACVGKQGLDLLVKGLSQAIL
HHHHHHCCCCCCHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHH
ARGYVTTRVLLPEQDLSTGTLKFSLVPGVIRHVHFADEKLRGTWKTAFPTRDGELLNLRD
HCCCEEEEEEECCCCCCCCEEEEEEHHHHHHHHHHCCHHHCCCEEECCCCCCCCEECHHH
LEQGLEQMKRVTSQDVSMQIVPADVPGESDVVLDVKRTKPWTVVASIDNSGTRATGRLQG
HHHHHHHHHHHHCCCCEEEEEECCCCCCCCEEEEEECCCCEEEEEEECCCCCEEEEEEEE
NLSLGIDNPLGLNDIFNIGVSQDLEFGDKRLGSHGWNGFYSIPWGYWTATLSAYTNTYYQ
EEEECCCCCCCCHHHHHCCCCCCCCHHHHHCCCCCCCCEEECCCHHHHHHHHHHHHHHHH
QIAGVNQTFIASGNSKTVDFKLSRVLSRSQNDVFGAQFRLSRRFGQSFIEDTEIPQQRRN
HHCCCCEEEEECCCCCEEEHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHCCCCCHHHCC
NTFVEFGLTDRHYFGNAQFDGMLAYRQGIGAFGAQDDSLAADGGPTYRYKMAVLDANLSV
CCEEEECCCCCEEECCCCCCCHHHHHHCCCCCCCCCCCCCCCCCCCEEEEEEEEECCCCC
PFAIAQQPFRYVTTFHGQYTGNTLYYIDDLTIGSRYTVRGFDGETMLAASRGLYWRNELQ
CHHHHCCCCEEEEEECCEECCCEEEEEEEEEECCEEEEECCCCCEEEEHHCCCEEHHHCC
APIGQTGQAIYAGIDYGRVWGPQPVTLVGTQLAGAVIGVKGSVATRLGAYGYDLFAGTPI
CCCCCCCCEEEEECCCCCCCCCCCEEEECHHHHCEEEECCCHHHHHHCCCCCHHHCCCCC
YKPSGFPTARVTVGFQVTAQF
CCCCCCCEEEEEEEEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 2407716 [H]