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The map label for this gene is yhcK [H]

Identifier: 126454383

GI number: 126454383

Start: 1408578

End: 1409978

Strand: Reverse

Name: yhcK [H]

Synonym: BURPS1106A_1449

Alternate gene names: 126454383

Gene position: 1409978-1408578 (Counterclockwise)

Preceding gene: 126451575

Following gene: 126453264

Centisome position: 35.35

GC content: 65.95

Gene sequence:

>1401_bases
GTGAGCACCGTCTTCACAGCCCATGAATCGCCGCGTGTGATCGGCACGATCGCCCGGCTCTACACCGCGTGCCTGCTGAT
CGGCTTCGCGCTCGTGCCGGCGTTCCTGATCGCCTATGTGCGGTTCTTCATCGATCCGCGGCTCGTCTTCGAGAACCATC
AGTTCCACGAACTGGCGATCGCCGCCGCGACGCTCGAGGGGCTGTTCGTCACCTACGTCACATGGCGCTGCTATCTGGCG
TCGGGCGAGCCGCTGCTGCGCTGGCTCACGCTCGGCTTCCTCGGCTTCGCGCTGATCTATTCGCTGCACGGCGCGTTCAC
CGGCATGGCGCACCAGAACATCTGGCTGTTCCTGCTGTACGGGCCCGCATCGCGCCTCGTGATGTCGATCCTGCTGCTCG
TCGGGCAACTGTCGTACTTCCGCGACGCCGATCCACCGGAGCGCCGCACGCATCTGTCGATGTGGCTGCCGTGGATCGCC
GGCTACGTCGTCGTGTGCTTCGCCGTGGCCGCGATCGCGTATTCGCCGATCGCCGGCCATCTGTGGACGCGCGCATCGAT
GGAGGGCGGCGCGATGATCGTGTCGCTCGTCAACGTCGCGCTGCTGCTCGTGCGGCGCATCCGCACGCCGCTGATGCTCG
TCTACGGCATCTCGGTGACGTCGTTCGCGCTGTCGTCGATCGCGTTCATTCTCGGCAAGCCGTGGAATCACATGTGGTGG
CTCGCGCACGCGGTCTTCGCGGGCGGCTTCTTCATGCTGAGCTTCGGCGTCGTGCAGGCGCTGATGACGACCCGCTCGTT
CGCGACCGTCTACAGCCAGCAGGACTTGATGGCGCGGCTCGCCGAATCGATGGCGCGCACCGAGGGCGTGCTGCAGGAGC
TCAAGCGCACCAATCAGAAGCTCGAGCACCTCGCGACCACCGATCCGCTGACGGGCGCGTCCAACCGGCGCAAGTTCATC
GAGCAGATGCAATCGGAGATCGCGCGCGCGAAACGCGACGGCACCGCGTTCTCGCTGCTCGCGCTCGATCTCGACAACTT
CAAGACGATCAACGACAACTACGGCCATCAGGTCGGCGACGTCGTGCTGCGCAATTTCGTGCGCCAGTGCCTCGCCGCGA
TTCGCCCTTACGACCACATCGCGCGCGTCGGCGGCGAGGAATTCATGGTGCTGCTGCCGCGCATGCTCGCCGACACGGCG
AGCGGCATCGCCGAGCGGGTGCGGACCACGATCGCGAACGCATCGTTCGGCATCGACGGCAAGCACACGCCCGTGACCGT
GAGCATCGGCGTGTCGCAGTACGGGCGCGATGGCGACACCGTCGACGAAATCCTGAGCGCCGCCGACAAGCTGCTCTATC
GCGCGAAGAACGAGGGGCGCAATCGCGTCGTCGCGTCGTAG

Upstream 100 bases:

>100_bases
GAAACGATGCGGCGCGGGACCCGGCGCGACGGCCGCTCGCCGCCCGGCGTCCCGCGCGGATTTCCCACTTCGATCCAGGA
ACAGCGTTGCGGAGGCCACC

Downstream 100 bases:

>100_bases
ACCCTCGTCAGCCGCGGGACAGCGGAGCGGGCGGGACGGCCCGATCGGCGGCGATCCGGCGCGCGCCACCGGGATCGCAA
GCCACGGCGCGGCGATTCGC

Product: diguanylate cyclase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 466; Mature: 465

Protein sequence:

>466_residues
MSTVFTAHESPRVIGTIARLYTACLLIGFALVPAFLIAYVRFFIDPRLVFENHQFHELAIAAATLEGLFVTYVTWRCYLA
SGEPLLRWLTLGFLGFALIYSLHGAFTGMAHQNIWLFLLYGPASRLVMSILLLVGQLSYFRDADPPERRTHLSMWLPWIA
GYVVVCFAVAAIAYSPIAGHLWTRASMEGGAMIVSLVNVALLLVRRIRTPLMLVYGISVTSFALSSIAFILGKPWNHMWW
LAHAVFAGGFFMLSFGVVQALMTTRSFATVYSQQDLMARLAESMARTEGVLQELKRTNQKLEHLATTDPLTGASNRRKFI
EQMQSEIARAKRDGTAFSLLALDLDNFKTINDNYGHQVGDVVLRNFVRQCLAAIRPYDHIARVGGEEFMVLLPRMLADTA
SGIAERVRTTIANASFGIDGKHTPVTVSIGVSQYGRDGDTVDEILSAADKLLYRAKNEGRNRVVAS

Sequences:

>Translated_466_residues
MSTVFTAHESPRVIGTIARLYTACLLIGFALVPAFLIAYVRFFIDPRLVFENHQFHELAIAAATLEGLFVTYVTWRCYLA
SGEPLLRWLTLGFLGFALIYSLHGAFTGMAHQNIWLFLLYGPASRLVMSILLLVGQLSYFRDADPPERRTHLSMWLPWIA
GYVVVCFAVAAIAYSPIAGHLWTRASMEGGAMIVSLVNVALLLVRRIRTPLMLVYGISVTSFALSSIAFILGKPWNHMWW
LAHAVFAGGFFMLSFGVVQALMTTRSFATVYSQQDLMARLAESMARTEGVLQELKRTNQKLEHLATTDPLTGASNRRKFI
EQMQSEIARAKRDGTAFSLLALDLDNFKTINDNYGHQVGDVVLRNFVRQCLAAIRPYDHIARVGGEEFMVLLPRMLADTA
SGIAERVRTTIANASFGIDGKHTPVTVSIGVSQYGRDGDTVDEILSAADKLLYRAKNEGRNRVVAS
>Mature_465_residues
STVFTAHESPRVIGTIARLYTACLLIGFALVPAFLIAYVRFFIDPRLVFENHQFHELAIAAATLEGLFVTYVTWRCYLAS
GEPLLRWLTLGFLGFALIYSLHGAFTGMAHQNIWLFLLYGPASRLVMSILLLVGQLSYFRDADPPERRTHLSMWLPWIAG
YVVVCFAVAAIAYSPIAGHLWTRASMEGGAMIVSLVNVALLLVRRIRTPLMLVYGISVTSFALSSIAFILGKPWNHMWWL
AHAVFAGGFFMLSFGVVQALMTTRSFATVYSQQDLMARLAESMARTEGVLQELKRTNQKLEHLATTDPLTGASNRRKFIE
QMQSEIARAKRDGTAFSLLALDLDNFKTINDNYGHQVGDVVLRNFVRQCLAAIRPYDHIARVGGEEFMVLLPRMLADTAS
GIAERVRTTIANASFGIDGKHTPVTVSIGVSQYGRDGDTVDEILSAADKLLYRAKNEGRNRVVAS

Specific function: Unknown

COG id: COG2199

COG function: function code T; FOG: GGDEF domain

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 GGDEF domain [H]

Homologues:

Organism=Escherichia coli, GI87081881, Length=182, Percent_Identity=44.5054945054945, Blast_Score=124, Evalue=2e-29,
Organism=Escherichia coli, GI1787262, Length=169, Percent_Identity=38.4615384615385, Blast_Score=116, Evalue=3e-27,
Organism=Escherichia coli, GI145693134, Length=162, Percent_Identity=35.1851851851852, Blast_Score=100, Evalue=2e-22,
Organism=Escherichia coli, GI1788381, Length=177, Percent_Identity=32.7683615819209, Blast_Score=100, Evalue=4e-22,
Organism=Escherichia coli, GI87082007, Length=161, Percent_Identity=38.5093167701863, Blast_Score=99, Evalue=7e-22,
Organism=Escherichia coli, GI1786584, Length=170, Percent_Identity=32.3529411764706, Blast_Score=98, Evalue=1e-21,
Organism=Escherichia coli, GI1788085, Length=179, Percent_Identity=33.5195530726257, Blast_Score=94, Evalue=2e-20,
Organism=Escherichia coli, GI1787802, Length=162, Percent_Identity=35.1851851851852, Blast_Score=93, Evalue=4e-20,
Organism=Escherichia coli, GI1787816, Length=160, Percent_Identity=31.875, Blast_Score=86, Evalue=6e-18,
Organism=Escherichia coli, GI1787541, Length=170, Percent_Identity=32.3529411764706, Blast_Score=83, Evalue=3e-17,
Organism=Escherichia coli, GI87081974, Length=170, Percent_Identity=26.4705882352941, Blast_Score=76, Evalue=5e-15,
Organism=Escherichia coli, GI87081977, Length=182, Percent_Identity=30.2197802197802, Blast_Score=72, Evalue=9e-14,
Organism=Escherichia coli, GI1788956, Length=173, Percent_Identity=32.3699421965318, Blast_Score=70, Evalue=4e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001054
- InterPro:   IPR000160
- InterPro:   IPR011620 [H]

Pfam domain/function: PF07694 5TM-5TMR_LYT; PF00990 GGDEF [H]

EC number: NA

Molecular weight: Translated: 51780; Mature: 51649

Theoretical pI: Translated: 9.36; Mature: 9.36

Prosite motif: PS50887 GGDEF

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSTVFTAHESPRVIGTIARLYTACLLIGFALVPAFLIAYVRFFIDPRLVFENHQFHELAI
CCCEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHEECCCCHHHHHH
AAATLEGLFVTYVTWRCYLASGEPLLRWLTLGFLGFALIYSLHGAFTGMAHQNIWLFLLY
HHHHHHHHHHHHHHHHHEECCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEE
GPASRLVMSILLLVGQLSYFRDADPPERRTHLSMWLPWIAGYVVVCFAVAAIAYSPIAGH
CCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHH
LWTRASMEGGAMIVSLVNVALLLVRRIRTPLMLVYGISVTSFALSSIAFILGKPWNHMWW
HHHHCCCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHH
LAHAVFAGGFFMLSFGVVQALMTTRSFATVYSQQDLMARLAESMARTEGVLQELKRTNQK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LEHLATTDPLTGASNRRKFIEQMQSEIARAKRDGTAFSLLALDLDNFKTINDNYGHQVGD
HHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCEEEEEEEECCCCEECCCCCCHHHHH
VVLRNFVRQCLAAIRPYDHIARVGGEEFMVLLPRMLADTASGIAERVRTTIANASFGIDG
HHHHHHHHHHHHHHCCHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
KHTPVTVSIGVSQYGRDGDTVDEILSAADKLLYRAKNEGRNRVVAS
CCCCEEEEECHHHCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCC
>Mature Secondary Structure 
STVFTAHESPRVIGTIARLYTACLLIGFALVPAFLIAYVRFFIDPRLVFENHQFHELAI
CCEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHEECCCCHHHHHH
AAATLEGLFVTYVTWRCYLASGEPLLRWLTLGFLGFALIYSLHGAFTGMAHQNIWLFLLY
HHHHHHHHHHHHHHHHHEECCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEE
GPASRLVMSILLLVGQLSYFRDADPPERRTHLSMWLPWIAGYVVVCFAVAAIAYSPIAGH
CCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHH
LWTRASMEGGAMIVSLVNVALLLVRRIRTPLMLVYGISVTSFALSSIAFILGKPWNHMWW
HHHHCCCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHH
LAHAVFAGGFFMLSFGVVQALMTTRSFATVYSQQDLMARLAESMARTEGVLQELKRTNQK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LEHLATTDPLTGASNRRKFIEQMQSEIARAKRDGTAFSLLALDLDNFKTINDNYGHQVGD
HHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCEEEEEEEECCCCEECCCCCCHHHHH
VVLRNFVRQCLAAIRPYDHIARVGGEEFMVLLPRMLADTASGIAERVRTTIANASFGIDG
HHHHHHHHHHHHHHCCHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
KHTPVTVSIGVSQYGRDGDTVDEILSAADKLLYRAKNEGRNRVVAS
CCCCEEEEECHHHCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8969498; 9384377 [H]