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The map label for this gene is pilQ [H]

Identifier: 126454219

GI number: 126454219

Start: 3670938

End: 3672335

Strand: Reverse

Name: pilQ [H]

Synonym: BURPS1106A_3759

Alternate gene names: 126454219

Gene position: 3672335-3670938 (Counterclockwise)

Preceding gene: 126453051

Following gene: 126454778

Centisome position: 92.07

GC content: 70.1

Gene sequence:

>1398_bases
GTGGCATCGGCGGGGTTGCAAGCGCAGGAGGCCGCGCTGGAGGGGCCGCCCGTGCCGCTCGCGCCGGCGCAACGCATGAG
CGACGAGAGCGACGAGAGCGACGAGCATCGTTCGTCGCCGCCGGCCGCCGACGCCGTATCGACCGCGAGCGTCGCCGGCA
CCGGCACCGAGACGGGCGATCCATCCGGCGACAATCGCCCGATCTCCATCAATCTGCAACAGGCGAGCCTCGCCGCGGTC
TTCGATGCATTCGCGCGTTTCACGGGCCTCAATATCGTGGTCAGCGAGCGGGTGCGCGGCACGGTGTCGTTGCGTCTGAA
CAATGTCCGCTGGCGCAGTGCGTTCGATGCGCTGCTGGACGCCCACGGCCTCGCGATGGCGCGGCGCGGCAGCGTGATAT
GGGTGGCGCCCGTCGCGGAACTCGCCGAGCGCGAGCGCCAGCGTTTCGATGCGCATGCGCGCGCCGCCCAGCTCGAGCCG
CTCGCGAGCCGCGGCTTCGTGCTGCGCTACGCGCGCGCGGCCGACGTGCAGCGTCTGCTCGCAGGCTCGGCCGGCCAGCG
CATCCTGTCCAAGCGCGGCTCGGTGTTGGCCGATCCTCGGACGAATCTGTTGTTCGTCACCGATCTGTCCGGACGCCTCG
CGCAGATCGCCGATCTGATCGGCAAGCTCGATACGCCGTCGCGCCAGGTATTGATCGAAGCGAGGATCGTCGAGGGCGAT
CGCGGGTTCTCGCGCAATCTCGGCGCGCGCCTCGCGCTGCGCGCGCCCGATGCGGGCGAACGCGCGACGGGCATCGTCGC
CGGCCGCAACGGCACGCTGGCGGAGCTCGCCGCCAGGCCGATCAGCGGCTTCGACGCGGCGACGGCCGGCCTCACGCTGT
TCGCCGCGCGCGCGAGCCGCCTGCTCGACGTCGAGTTGAGCGCGCTCGAGGCCGAGGGCCGGGGCCAGATCGTGTCGAGC
CCGCGCGTCGTGACGGCGGACCGGACCAAGGCCGTCGTCGAGCAGGGCGCCGAGCTGCCGTACCAGGCGAAGGTCGGCAA
CGGCGTATCCGGCGTCCAGTTCCGGCGCGCGACCTTGAAGCTCGAGGTCGAGCCGCAGATCACGCCCGACGGGCGTGTGA
TTCTCGATCTCGATGTCGCGAAGGATAGCGTCGGCGAGGAAACCGCGTCCGGCCCCGCGATTCATACGAAGCATGTGCAG
ACGCGAGTGGAAGTCGAAAACGGCGGAACGGTGTCGATCGGCGGGATTTTCGAGAGCGACGACCGCGACGATGTGACTCG
CGTGCCGCTCTTGGGCAAAATACCGGTGTTGGGCGCGCTTTTCAGGCATCGCGCGCAGCGTGCGCAGCGCAGCGAGCTCG
TCGTCTACATCACGCCGACCGTCGTGATCGGGCCCTGA

Upstream 100 bases:

>100_bases
GGCTGAATTCGCCGGCGAGGCCATGCCCGAACGCATGCCGGCGGCCCCAACGGCGGAACCGGCCCGCTCGACGTCCGCCG
ACGCCGGAACGTCGAGCGCA

Downstream 100 bases:

>100_bases
CGCCCGTGGGAGCCAGGCTCGACAAGGCGGGCGCTTTGCCAGTAAGCTGCGCGACACACTCACTGAAGCAGAGGAAGCCG
TTGCAAGCGCGGGATCCACA

Product: type IV pilus secretin PilQ

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 465; Mature: 464

Protein sequence:

>465_residues
MASAGLQAQEAALEGPPVPLAPAQRMSDESDESDEHRSSPPAADAVSTASVAGTGTETGDPSGDNRPISINLQQASLAAV
FDAFARFTGLNIVVSERVRGTVSLRLNNVRWRSAFDALLDAHGLAMARRGSVIWVAPVAELAERERQRFDAHARAAQLEP
LASRGFVLRYARAADVQRLLAGSAGQRILSKRGSVLADPRTNLLFVTDLSGRLAQIADLIGKLDTPSRQVLIEARIVEGD
RGFSRNLGARLALRAPDAGERATGIVAGRNGTLAELAARPISGFDAATAGLTLFAARASRLLDVELSALEAEGRGQIVSS
PRVVTADRTKAVVEQGAELPYQAKVGNGVSGVQFRRATLKLEVEPQITPDGRVILDLDVAKDSVGEETASGPAIHTKHVQ
TRVEVENGGTVSIGGIFESDDRDDVTRVPLLGKIPVLGALFRHRAQRAQRSELVVYITPTVVIGP

Sequences:

>Translated_465_residues
MASAGLQAQEAALEGPPVPLAPAQRMSDESDESDEHRSSPPAADAVSTASVAGTGTETGDPSGDNRPISINLQQASLAAV
FDAFARFTGLNIVVSERVRGTVSLRLNNVRWRSAFDALLDAHGLAMARRGSVIWVAPVAELAERERQRFDAHARAAQLEP
LASRGFVLRYARAADVQRLLAGSAGQRILSKRGSVLADPRTNLLFVTDLSGRLAQIADLIGKLDTPSRQVLIEARIVEGD
RGFSRNLGARLALRAPDAGERATGIVAGRNGTLAELAARPISGFDAATAGLTLFAARASRLLDVELSALEAEGRGQIVSS
PRVVTADRTKAVVEQGAELPYQAKVGNGVSGVQFRRATLKLEVEPQITPDGRVILDLDVAKDSVGEETASGPAIHTKHVQ
TRVEVENGGTVSIGGIFESDDRDDVTRVPLLGKIPVLGALFRHRAQRAQRSELVVYITPTVVIGP
>Mature_464_residues
ASAGLQAQEAALEGPPVPLAPAQRMSDESDESDEHRSSPPAADAVSTASVAGTGTETGDPSGDNRPISINLQQASLAAVF
DAFARFTGLNIVVSERVRGTVSLRLNNVRWRSAFDALLDAHGLAMARRGSVIWVAPVAELAERERQRFDAHARAAQLEPL
ASRGFVLRYARAADVQRLLAGSAGQRILSKRGSVLADPRTNLLFVTDLSGRLAQIADLIGKLDTPSRQVLIEARIVEGDR
GFSRNLGARLALRAPDAGERATGIVAGRNGTLAELAARPISGFDAATAGLTLFAARASRLLDVELSALEAEGRGQIVSSP
RVVTADRTKAVVEQGAELPYQAKVGNGVSGVQFRRATLKLEVEPQITPDGRVILDLDVAKDSVGEETASGPAIHTKHVQT
RVEVENGGTVSIGGIFESDDRDDVTRVPLLGKIPVLGALFRHRAQRAQRSELVVYITPTVVIGP

Specific function: Required for type IV pilus biogenesis and competence. Could function as a pore for exit of the pilus but also as a channel for entry of heme and antimicrobial agents and uptake of transforming DNA [H]

COG id: COG4796

COG function: function code U; Type II secretory pathway, component HofQ

Gene ontology:

Cell location: Cell outer membrane [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GSP D family [H]

Homologues:

Organism=Escherichia coli, GI1789793, Length=403, Percent_Identity=33.9950372208437, Blast_Score=206, Evalue=2e-54,
Organism=Escherichia coli, GI87082242, Length=382, Percent_Identity=27.4869109947644, Blast_Score=125, Evalue=5e-30,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001775
- InterPro:   IPR005644
- InterPro:   IPR013355
- InterPro:   IPR011662
- InterPro:   IPR004846
- InterPro:   IPR004845 [H]

Pfam domain/function: PF00263 Secretin; PF03958 Secretin_N; PF07660 STN [H]

EC number: NA

Molecular weight: Translated: 49269; Mature: 49138

Theoretical pI: Translated: 7.20; Mature: 7.20

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
0.6 %Met     (Translated Protein)
0.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.4 %Met     (Mature Protein)
0.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MASAGLQAQEAALEGPPVPLAPAQRMSDESDESDEHRSSPPAADAVSTASVAGTGTETGD
CCCCCCCHHHHHCCCCCCCCCCHHHCCCCCCCCHHHCCCCCCHHHHHHCEECCCCCCCCC
PSGDNRPISINLQQASLAAVFDAFARFTGLNIVVSERVRGTVSLRLNNVRWRSAFDALLD
CCCCCCCEEEEEHHHHHHHHHHHHHHHCCCEEEEECCCCEEEEEEEECEEHHHHHHHHHH
AHGLAMARRGSVIWVAPVAELAERERQRFDAHARAAQLEPLASRGFVLRYARAADVQRLL
HHHHHEECCCCEEEEECHHHHHHHHHHHHHHHHHHHHCCHHHHCCEEEEEHHHHHHHHHH
AGSAGQRILSKRGSVLADPRTNLLFVTDLSGRLAQIADLIGKLDTPSRQVLIEARIVEGD
CCCHHHHHHHHCCCEEECCCCCEEEEECCCCHHHHHHHHHHCCCCCCCEEEEEEEEEECC
RGFSRNLGARLALRAPDAGERATGIVAGRNGTLAELAARPISGFDAATAGLTLFAARASR
CCCCCCCCCEEEEECCCCCCCCEEEEECCCCCHHHHHCCCCCCCCHHHHHHHHHHHHHHH
LLDVELSALEAEGRGQIVSSPRVVTADRTKAVVEQGAELPYQAKVGNGVSGVQFRRATLK
EEEEEEEEECCCCCCCEECCCEEEECCHHHHHHHCCCCCCEEEECCCCCCCCEEEEEEEE
LEVEPQITPDGRVILDLDVAKDSVGEETASGPAIHTKHVQTRVEVENGGTVSIGGIFESD
EEECCCCCCCCEEEEEEECCCCCCCCCCCCCCCEEEEEEEEEEEECCCCEEEECCEECCC
DRDDVTRVPLLGKIPVLGALFRHRAQRAQRSELVVYITPTVVIGP
CCCCCEECCCCCCCHHHHHHHHHHHHHHHHCCEEEEEECEEEECC
>Mature Secondary Structure 
ASAGLQAQEAALEGPPVPLAPAQRMSDESDESDEHRSSPPAADAVSTASVAGTGTETGD
CCCCCCHHHHHCCCCCCCCCCHHHCCCCCCCCHHHCCCCCCHHHHHHCEECCCCCCCCC
PSGDNRPISINLQQASLAAVFDAFARFTGLNIVVSERVRGTVSLRLNNVRWRSAFDALLD
CCCCCCCEEEEEHHHHHHHHHHHHHHHCCCEEEEECCCCEEEEEEEECEEHHHHHHHHHH
AHGLAMARRGSVIWVAPVAELAERERQRFDAHARAAQLEPLASRGFVLRYARAADVQRLL
HHHHHEECCCCEEEEECHHHHHHHHHHHHHHHHHHHHCCHHHHCCEEEEEHHHHHHHHHH
AGSAGQRILSKRGSVLADPRTNLLFVTDLSGRLAQIADLIGKLDTPSRQVLIEARIVEGD
CCCHHHHHHHHCCCEEECCCCCEEEEECCCCHHHHHHHHHHCCCCCCCEEEEEEEEEECC
RGFSRNLGARLALRAPDAGERATGIVAGRNGTLAELAARPISGFDAATAGLTLFAARASR
CCCCCCCCCEEEEECCCCCCCCEEEEECCCCCHHHHHCCCCCCCCHHHHHHHHHHHHHHH
LLDVELSALEAEGRGQIVSSPRVVTADRTKAVVEQGAELPYQAKVGNGVSGVQFRRATLK
EEEEEEEEECCCCCCCEECCCEEEECCHHHHHHHCCCCCCEEEECCCCCCCCEEEEEEEE
LEVEPQITPDGRVILDLDVAKDSVGEETASGPAIHTKHVQTRVEVENGGTVSIGGIFESD
EEECCCCCCCCEEEEEEECCCCCCCCCCCCCCCEEEEEEEEEEEECCCCEEEECCEECCC
DRDDVTRVPLLGKIPVLGALFRHRAQRAQRSELVVYITPTVVIGP
CCCCCEECCCCCCCHHHHHHHHHHHHHHHHCCEEEEEECEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10710307 [H]