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The map label for this gene is tpm [H]

Identifier: 126454217

GI number: 126454217

Start: 662554

End: 663348

Strand: Direct

Name: tpm [H]

Synonym: BURPS1106A_0688

Alternate gene names: 126454217

Gene position: 662554-663348 (Clockwise)

Preceding gene: 126453187

Following gene: 126454052

Centisome position: 16.61

GC content: 71.95

Gene sequence:

>795_bases
ATGAAGGACAGGCTTATGAGTCAAGGCGACGGCGTGACGAGCGAAGCGAACCAACCTGAGGCGGCCGGGCAGGCGACGGG
CGATGCGCAGCCGGCAAGTCCGGCGGGGCCGGCGCATATCGCGAATCCCGCGAATCCTGCGAATCCGCCGGCCTTGCCCT
CGCTCTCGCCGCCCGCGGCGGCGCCGTCTTCCGCGTCGTCCGCCGCGCACTTTTCGTCGCGCGATCCGGGCGATGCTTCG
TTCTGGGACGAGCGTTTCGAACAGGGCGTGACGCCGTGGGACAGCGCGCGCGTGCCGGATGCGTTCGCCGCGTTCGCCGC
CCGGCATGCGCGAGTCCCGGTGCTGATCCCCGGCTGCGGCAGCGCTTACGAGGCGCGTTGGCTCGCGCGCGCCGGCTGGC
CCGTGCGCGCGATCGATTTTTCCGCCCAGGCGGTTGCCGCCGCGCGCCGCGAACTGGGCGAGGACGCCGGGCTCGTCGAG
CAGGCCGATTTCTTCACGTACGCGCCGCCGTTCGTCCCGCAGTGGATCTATGAGCGCGCGTTCCTGTGCGCGATTCCGAG
GAGCCGCCGCGCCGACTACGCGCGGCGCATGGCCGAGCTCTTGCCGCCGGGCGGCTTCCTCGCCGGCTTCTTCTTCATCG
GCGCGACGCCGAAAGGGCCGCCGTTCGGCATCGAGCGCGCGGAACTCGATGCGCTCCTTTGCCCGCACTTCGCGCTGGTC
GAGGACGAGCCCGTCGCCGATTCGCTGCCGGTATTCGCCGGCCGCGAGCGCTGGCTCGCGTGGCGCCGCTCGTAG

Upstream 100 bases:

>100_bases
GCGATGCGGGCGCGAGGTAGGTTTGAAGCGGGTTCGAAGCGGGTTCGAACGGCGGCCGGATACGGTCCACGGACGGCGCG
AAGCGTGCGGATGACGGCGG

Downstream 100 bases:

>100_bases
CGGCGCGCCCGCGCGGACCGAGGGAGGCGTTCGCCTTTCGGCTATAATTCAAGGCTTTGCAAGCCTTTTATACCGGTTCT
TGTTTCTGCGGGAAGATACC

Product: putative thiopurine S-methyltransferase

Products: NA

Alternate protein names: Thiopurine methyltransferase [H]

Number of amino acids: Translated: 264; Mature: 264

Protein sequence:

>264_residues
MKDRLMSQGDGVTSEANQPEAAGQATGDAQPASPAGPAHIANPANPANPPALPSLSPPAAAPSSASSAAHFSSRDPGDAS
FWDERFEQGVTPWDSARVPDAFAAFAARHARVPVLIPGCGSAYEARWLARAGWPVRAIDFSAQAVAAARRELGEDAGLVE
QADFFTYAPPFVPQWIYERAFLCAIPRSRRADYARRMAELLPPGGFLAGFFFIGATPKGPPFGIERAELDALLCPHFALV
EDEPVADSLPVFAGRERWLAWRRS

Sequences:

>Translated_264_residues
MKDRLMSQGDGVTSEANQPEAAGQATGDAQPASPAGPAHIANPANPANPPALPSLSPPAAAPSSASSAAHFSSRDPGDAS
FWDERFEQGVTPWDSARVPDAFAAFAARHARVPVLIPGCGSAYEARWLARAGWPVRAIDFSAQAVAAARRELGEDAGLVE
QADFFTYAPPFVPQWIYERAFLCAIPRSRRADYARRMAELLPPGGFLAGFFFIGATPKGPPFGIERAELDALLCPHFALV
EDEPVADSLPVFAGRERWLAWRRS
>Mature_264_residues
MKDRLMSQGDGVTSEANQPEAAGQATGDAQPASPAGPAHIANPANPANPPALPSLSPPAAAPSSASSAAHFSSRDPGDAS
FWDERFEQGVTPWDSARVPDAFAAFAARHARVPVLIPGCGSAYEARWLARAGWPVRAIDFSAQAVAAARRELGEDAGLVE
QADFFTYAPPFVPQWIYERAFLCAIPRSRRADYARRMAELLPPGGFLAGFFFIGATPKGPPFGIERAELDALLCPHFALV
EDEPVADSLPVFAGRERWLAWRRS

Specific function: Unknown

COG id: COG0500

COG function: function code QR; SAM-dependent methyltransferases

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the methyltransferase superfamily. TPMT family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022474
- InterPro:   IPR008854
- InterPro:   IPR016822 [H]

Pfam domain/function: PF05724 TPMT [H]

EC number: =2.1.1.67 [H]

Molecular weight: Translated: 28237; Mature: 28237

Theoretical pI: Translated: 5.13; Mature: 5.13

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKDRLMSQGDGVTSEANQPEAAGQATGDAQPASPAGPAHIANPANPANPPALPSLSPPAA
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
APSSASSAAHFSSRDPGDASFWDERFEQGVTPWDSARVPDAFAAFAARHARVPVLIPGCG
CCCCCCHHHHCCCCCCCCHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHCCCCEEECCCC
SAYEARWLARAGWPVRAIDFSAQAVAAARRELGEDAGLVEQADFFTYAPPFVPQWIYERA
CHHHHHHHHHCCCCEEEECCHHHHHHHHHHHHCCCCCCHHHCCCCCCCCCCHHHHHHHHH
FLCAIPRSRRADYARRMAELLPPGGFLAGFFFIGATPKGPPFGIERAELDALLCPHFALV
HHHCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCCCCCCCHHHHHHHHCCCEEEE
EDEPVADSLPVFAGRERWLAWRRS
CCCCCCCCCCCCCCHHHHHHCCCC
>Mature Secondary Structure
MKDRLMSQGDGVTSEANQPEAAGQATGDAQPASPAGPAHIANPANPANPPALPSLSPPAA
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
APSSASSAAHFSSRDPGDASFWDERFEQGVTPWDSARVPDAFAAFAARHARVPVLIPGCG
CCCCCCHHHHCCCCCCCCHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHCCCCEEECCCC
SAYEARWLARAGWPVRAIDFSAQAVAAARRELGEDAGLVEQADFFTYAPPFVPQWIYERA
CHHHHHHHHHCCCCEEEECCHHHHHHHHHHHHCCCCCCHHHCCCCCCCCCCHHHHHHHHH
FLCAIPRSRRADYARRMAELLPPGGFLAGFFFIGATPKGPPFGIERAELDALLCPHFALV
HHHCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCCCCCCCHHHHHHHHCCCEEEE
EDEPVADSLPVFAGRERWLAWRRS
CCCCCCCCCCCCCCHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA