Click here to switch to the map view.

The map label for this gene is ispH [H]

Identifier: 126454143

GI number: 126454143

Start: 967292

End: 968272

Strand: Direct

Name: ispH [H]

Synonym: BURPS1106A_0986

Alternate gene names: 126454143

Gene position: 967292-968272 (Clockwise)

Preceding gene: 126455033

Following gene: 126452273

Centisome position: 24.25

GC content: 68.2

Gene sequence:

>981_bases
ATGAGCTCCACCGATACGTTGTCCGGCCAGGTTGCCGCGGCCGACGCCGAGATCCTGCTCGCCCAGCCGCGCGGCTTCTG
CGCGGGTGTCGACCGCGCGATCGAGATCGTCGAGCGTGCGATTGCGATGCACGGCGCGCCGATCTACGTGCGCCACGAGA
TCGTGCACAACAAGTACGTCGTCGAGGATCTGAAGAAGAAGGGCGCGATTTTTGTCGAGGAACTCGAGGAAGTGCCGTCC
GGCAACACGGTGATCTTCAGCGCGCACGGCGTGTCGAAGGCGGTGCGCGACGAGGCGGCCGTGCGCGGGCTGCGCATCTA
CGATGCGACGTGCCCGCTCGTCACGAAAGTGCACGTCGAGGTCGCGAAGATGCGCCAGGAAGGCGTCGACATCGTGATGA
TCGGCCACAAGGGGCATCCGGAGGTCGAGGGCACGATGGGGCAGGTCGAGCGCGGCATGCACCTCGTCGAGAGCGTCGAG
GACGTGCGCCGGCTCGAGCTGCCCGATCCCGAGCGCGTCGCGCTCGTCACGCAGACGACGCTGTCCGTCGACGACGCGGC
CGAGATCATCGGCGCGTTGAGGGCGAAGTTTCCCGCGATCCGCGAGCCGAAGAAGCAGGACATCTGCTACGCGACGCAGA
ACCGCCAGGACGCGGTGAAGTTCATGGCGCCGCAGTGCGACGTCGTGATCGTCGTCGGCAGCCCGAATAGCTCGAATTCG
AGCCGCCTGCGCGAGGTCGCCGAGAAGCGCGGCGTCGCCGCCTACATGGTCGACGCGCCCGAGCAGATCGATCCGGCCTG
GGTCGCCGGCAAGCGCCGGATCGGCGTGACCGCCGGCGCGTCCGCGCCCGAGGTGCTCGCGCAGGCCGTGATCGCGCGCT
TGCGCGAGCTCGGCGTGACCAACGTGCGGGCGCTCGAGGGCATCGAGGAGAACGTGTCGTTCCCATTGCCGCGCGGCCTG
AATCTGTCTTCCGCCGGCTGA

Upstream 100 bases:

>100_bases
TCAAGGAGATCGGCGAGACCTCCGCGCTCTTCGATTTCAATCATCCGCTCGCGGGCCAGGCGCTCACGTTCGAAGTGAAT
ATCATCGGGATTCTGTAATC

Downstream 100 bases:

>100_bases
TTTTCGCCGCTCGATCGCCGGTTTCGTCTCCGTTGGAATGCAAAAGCGCGCCCTAGCAGGCTGTTGAAATTGGATACGGT
GTAAACGGGCGTTGCGAGCG

Product: 4-hydroxy-3-methylbut-2-enyl diphosphate reductase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 326; Mature: 325

Protein sequence:

>326_residues
MSSTDTLSGQVAAADAEILLAQPRGFCAGVDRAIEIVERAIAMHGAPIYVRHEIVHNKYVVEDLKKKGAIFVEELEEVPS
GNTVIFSAHGVSKAVRDEAAVRGLRIYDATCPLVTKVHVEVAKMRQEGVDIVMIGHKGHPEVEGTMGQVERGMHLVESVE
DVRRLELPDPERVALVTQTTLSVDDAAEIIGALRAKFPAIREPKKQDICYATQNRQDAVKFMAPQCDVVIVVGSPNSSNS
SRLREVAEKRGVAAYMVDAPEQIDPAWVAGKRRIGVTAGASAPEVLAQAVIARLRELGVTNVRALEGIEENVSFPLPRGL
NLSSAG

Sequences:

>Translated_326_residues
MSSTDTLSGQVAAADAEILLAQPRGFCAGVDRAIEIVERAIAMHGAPIYVRHEIVHNKYVVEDLKKKGAIFVEELEEVPS
GNTVIFSAHGVSKAVRDEAAVRGLRIYDATCPLVTKVHVEVAKMRQEGVDIVMIGHKGHPEVEGTMGQVERGMHLVESVE
DVRRLELPDPERVALVTQTTLSVDDAAEIIGALRAKFPAIREPKKQDICYATQNRQDAVKFMAPQCDVVIVVGSPNSSNS
SRLREVAEKRGVAAYMVDAPEQIDPAWVAGKRRIGVTAGASAPEVLAQAVIARLRELGVTNVRALEGIEENVSFPLPRGL
NLSSAG
>Mature_325_residues
SSTDTLSGQVAAADAEILLAQPRGFCAGVDRAIEIVERAIAMHGAPIYVRHEIVHNKYVVEDLKKKGAIFVEELEEVPSG
NTVIFSAHGVSKAVRDEAAVRGLRIYDATCPLVTKVHVEVAKMRQEGVDIVMIGHKGHPEVEGTMGQVERGMHLVESVED
VRRLELPDPERVALVTQTTLSVDDAAEIIGALRAKFPAIREPKKQDICYATQNRQDAVKFMAPQCDVVIVVGSPNSSNSS
RLREVAEKRGVAAYMVDAPEQIDPAWVAGKRRIGVTAGASAPEVLAQAVIARLRELGVTNVRALEGIEENVSFPLPRGLN
LSSAG

Specific function: Converts 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate into isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP) [H]

COG id: COG0761

COG function: function code IM; Penicillin tolerance protein

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ispH family [H]

Homologues:

Organism=Escherichia coli, GI1786212, Length=307, Percent_Identity=58.3061889250814, Blast_Score=372, Evalue=1e-104,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003451 [H]

Pfam domain/function: PF02401 LYTB [H]

EC number: =1.17.1.2 [H]

Molecular weight: Translated: 35177; Mature: 35046

Theoretical pI: Translated: 5.90; Mature: 5.90

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSSTDTLSGQVAAADAEILLAQPRGFCAGVDRAIEIVERAIAMHGAPIYVRHEIVHNKYV
CCCCCCCCCEEEECCCEEEEECCCCHHHHHHHHHHHHHHHHHHCCCCEEEEHHHHHHHHH
VEDLKKKGAIFVEELEEVPSGNTVIFSAHGVSKAVRDEAAVRGLRIYDATCPLVTKVHVE
HHHHHHCCCEEHHHHHHCCCCCEEEEECCCCHHHHHHHHHHCCEEEEECCCCHHHHHHHH
VAKMRQEGVDIVMIGHKGHPEVEGTMGQVERGMHLVESVEDVRRLELPDPERVALVTQTT
HHHHHHCCCCEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEEEE
LSVDDAAEIIGALRAKFPAIREPKKQDICYATQNRQDAVKFMAPQCDVVIVVGSPNSSNS
CCHHHHHHHHHHHHHHCCCCCCCCCCCCEEECCCHHHHHHHHCCCCCEEEEEECCCCCCH
SRLREVAEKRGVAAYMVDAPEQIDPAWVAGKRRIGVTAGASAPEVLAQAVIARLRELGVT
HHHHHHHHHCCCEEEEECCCCCCCCHHHCCCCEEEEECCCCCHHHHHHHHHHHHHHCCCC
NVRALEGIEENVSFPLPRGLNLSSAG
HHHHHHCHHHCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
SSTDTLSGQVAAADAEILLAQPRGFCAGVDRAIEIVERAIAMHGAPIYVRHEIVHNKYV
CCCCCCCCEEEECCCEEEEECCCCHHHHHHHHHHHHHHHHHHCCCCEEEEHHHHHHHHH
VEDLKKKGAIFVEELEEVPSGNTVIFSAHGVSKAVRDEAAVRGLRIYDATCPLVTKVHVE
HHHHHHCCCEEHHHHHHCCCCCEEEEECCCCHHHHHHHHHHCCEEEEECCCCHHHHHHHH
VAKMRQEGVDIVMIGHKGHPEVEGTMGQVERGMHLVESVEDVRRLELPDPERVALVTQTT
HHHHHHCCCCEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEEEE
LSVDDAAEIIGALRAKFPAIREPKKQDICYATQNRQDAVKFMAPQCDVVIVVGSPNSSNS
CCHHHHHHHHHHHHHHCCCCCCCCCCCCEEECCCHHHHHHHHCCCCCEEEEEECCCCCCH
SRLREVAEKRGVAAYMVDAPEQIDPAWVAGKRRIGVTAGASAPEVLAQAVIARLRELGVT
HHHHHHHHHCCCEEEEECCCCCCCCHHHCCCCEEEEECCCCCHHHHHHHHHHHHHHCCCC
NVRALEGIEENVSFPLPRGLNLSSAG
HHHHHHCHHHCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA