BacMap

Definition	Burkholderia pseudomallei 1106a chromosome I, complete genome.
Accession	NC_009076
Length	3,988,455

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The map label for this gene is phbB [H]

Identifier: 126454082

GI number: 126454082

Start: 2188639

End: 2189379

Strand: Reverse

Name: phbB [H]

Synonym: BURPS1106A_2201

Alternate gene names: 126454082

Gene position: 2189379-2188639 (Counterclockwise)

Preceding gene: 126453858

Following gene: 126451521

Centisome position: 54.89

GC content: 63.56

Gene sequence:

>741_bases
ATGTCTCAGCGAATTGCTTACGTAACGGGCGGCATGGGCGGCATCGGCACGAGCATCTGCCAGCGCCTGCACAAGGACGG
CTTCAGGGTGGTCGCGGGCTGCGGCCCGAATTCGCCGCGCCGCGTGAAATGGCTCGAGGATCAGAAGGCGCTCGGCTTCG
ATTTCTACGCGTCCGAAGGCAACGTCGGCGACTGGGATTCGACGAAGCAGGCGTTCGACAAGGTGAAGGCCGAAGTGGGC
GAGATCGACGTGCTCGTCAATAACGCGGGCATCACGCGCGACGTCGTGTTCCGCAAGATGACCCGCGAGGATTGGCAGGC
GGTGATCGACACGAACCTGACGAGTCTCTTCAACGTCACGAAGCAGGTGATCGACGGGATGGTCGAGCGCGGCTGGGGGC
GCATCATCAACATCTCGTCGGTGAACGGCCAGAAGGGGCAGTTCGGCCAGACCAACTATTCGACCGCGAAGGCGGGCATT
CACGGCTTCACGATGTCGCTCGCGCAGGAAGTCGCGACGAAGGGGGTGACGGTCAACACGGTGTCGCCGGGCTACATCGG
CACGGACATGGTGAAGGCGATTCGGCCGGACGTGCTCGAGAAGATCGTCGCGACGATTCCGGTGCGCCGTCTCGGCTCGC
CCGACGAGATCGGCTCGATCGTCGCGTGGCTCGCGTCGGAAGAGTCCGGGTTCTCGACGGGCGCCGATTTTTCGCTGAAC
GGCGGCTTGCATATGGGCTGA

Upstream 100 bases:

>100_bases
GGCGCGCCGGCGGGCGCGGCCCGACGAACGGGCGATCGGCAGGCAGGCGACGGAGAGGTTGCCGCTCGGCGCTTCTCAAA
ACGATAATGGAGTAATGGTT

Downstream 100 bases:

>100_bases
GCCATGCGGCCGGGCGGCGCGTGCCGTCCGGCCGTGTGGGTCGGATGTTCCGGGAACGCCCGGTGCCGCGCGCGGTCGCG
CCCGCGTGCGGCGCCGGGCG

Product: acetyacetyl-CoA reductase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 246; Mature: 245

Protein sequence:

>246_residues
MSQRIAYVTGGMGGIGTSICQRLHKDGFRVVAGCGPNSPRRVKWLEDQKALGFDFYASEGNVGDWDSTKQAFDKVKAEVG
EIDVLVNNAGITRDVVFRKMTREDWQAVIDTNLTSLFNVTKQVIDGMVERGWGRIINISSVNGQKGQFGQTNYSTAKAGI
HGFTMSLAQEVATKGVTVNTVSPGYIGTDMVKAIRPDVLEKIVATIPVRRLGSPDEIGSIVAWLASEESGFSTGADFSLN
GGLHMG

Sequences:

>Translated_246_residues
MSQRIAYVTGGMGGIGTSICQRLHKDGFRVVAGCGPNSPRRVKWLEDQKALGFDFYASEGNVGDWDSTKQAFDKVKAEVG
EIDVLVNNAGITRDVVFRKMTREDWQAVIDTNLTSLFNVTKQVIDGMVERGWGRIINISSVNGQKGQFGQTNYSTAKAGI
HGFTMSLAQEVATKGVTVNTVSPGYIGTDMVKAIRPDVLEKIVATIPVRRLGSPDEIGSIVAWLASEESGFSTGADFSLN
GGLHMG
>Mature_245_residues
SQRIAYVTGGMGGIGTSICQRLHKDGFRVVAGCGPNSPRRVKWLEDQKALGFDFYASEGNVGDWDSTKQAFDKVKAEVGE
IDVLVNNAGITRDVVFRKMTREDWQAVIDTNLTSLFNVTKQVIDGMVERGWGRIINISSVNGQKGQFGQTNYSTAKAGIH
GFTMSLAQEVATKGVTVNTVSPGYIGTDMVKAIRPDVLEKIVATIPVRRLGSPDEIGSIVAWLASEESGFSTGADFSLNG
GLHMG

Specific function: Fatty acid biosynthesis pathway; first reduction step. [C]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI15277342, Length=253, Percent_Identity=35.9683794466403, Blast_Score=145, Evalue=3e-35,
Organism=Homo sapiens, GI40254992, Length=246, Percent_Identity=32.9268292682927, Blast_Score=131, Evalue=7e-31,
Organism=Homo sapiens, GI4758504, Length=254, Percent_Identity=32.2834645669291, Blast_Score=107, Evalue=9e-24,
Organism=Homo sapiens, GI4504505, Length=249, Percent_Identity=32.5301204819277, Blast_Score=103, Evalue=2e-22,
Organism=Homo sapiens, GI32483357, Length=247, Percent_Identity=29.1497975708502, Blast_Score=102, Evalue=2e-22,
Organism=Homo sapiens, GI7705925, Length=249, Percent_Identity=28.1124497991968, Blast_Score=97, Evalue=2e-20,
Organism=Homo sapiens, GI83715985, Length=254, Percent_Identity=30.7086614173228, Blast_Score=91, Evalue=1e-18,
Organism=Homo sapiens, GI19923817, Length=250, Percent_Identity=28.8, Blast_Score=91, Evalue=1e-18,
Organism=Homo sapiens, GI10190704, Length=247, Percent_Identity=27.5303643724696, Blast_Score=87, Evalue=1e-17,
Organism=Homo sapiens, GI126723750, Length=256, Percent_Identity=27.734375, Blast_Score=84, Evalue=1e-16,
Organism=Homo sapiens, GI5031737, Length=246, Percent_Identity=27.6422764227642, Blast_Score=84, Evalue=1e-16,
Organism=Homo sapiens, GI66933014, Length=187, Percent_Identity=29.4117647058824, Blast_Score=83, Evalue=3e-16,
Organism=Homo sapiens, GI59889578, Length=194, Percent_Identity=30.4123711340206, Blast_Score=82, Evalue=4e-16,
Organism=Homo sapiens, GI7705855, Length=209, Percent_Identity=30.622009569378, Blast_Score=80, Evalue=2e-15,
Organism=Homo sapiens, GI109715829, Length=239, Percent_Identity=24.6861924686192, Blast_Score=79, Evalue=3e-15,
Organism=Homo sapiens, GI40548397, Length=207, Percent_Identity=29.4685990338164, Blast_Score=78, Evalue=9e-15,
Organism=Homo sapiens, GI214010158, Length=207, Percent_Identity=29.4685990338164, Blast_Score=78, Evalue=9e-15,
Organism=Homo sapiens, GI214010156, Length=207, Percent_Identity=29.4685990338164, Blast_Score=78, Evalue=9e-15,
Organism=Homo sapiens, GI22758144, Length=207, Percent_Identity=29.4685990338164, Blast_Score=78, Evalue=9e-15,
Organism=Homo sapiens, GI33667109, Length=198, Percent_Identity=30.8080808080808, Blast_Score=78, Evalue=9e-15,
Organism=Homo sapiens, GI31542939, Length=206, Percent_Identity=29.6116504854369, Blast_Score=77, Evalue=2e-14,
Organism=Homo sapiens, GI7706318, Length=201, Percent_Identity=27.8606965174129, Blast_Score=76, Evalue=3e-14,
Organism=Homo sapiens, GI150247226, Length=191, Percent_Identity=29.8429319371728, Blast_Score=75, Evalue=7e-14,
Organism=Homo sapiens, GI7657478, Length=191, Percent_Identity=28.7958115183246, Blast_Score=73, Evalue=3e-13,
Organism=Homo sapiens, GI22507405, Length=187, Percent_Identity=29.4117647058824, Blast_Score=71, Evalue=7e-13,
Organism=Homo sapiens, GI50726952, Length=193, Percent_Identity=31.0880829015544, Blast_Score=69, Evalue=3e-12,
Organism=Homo sapiens, GI19743808, Length=193, Percent_Identity=29.0155440414508, Blast_Score=69, Evalue=4e-12,
Organism=Homo sapiens, GI20149619, Length=200, Percent_Identity=26.5, Blast_Score=69, Evalue=4e-12,
Organism=Homo sapiens, GI4503817, Length=184, Percent_Identity=28.804347826087, Blast_Score=66, Evalue=2e-11,
Organism=Homo sapiens, GI44680136, Length=188, Percent_Identity=28.7234042553192, Blast_Score=65, Evalue=4e-11,
Organism=Homo sapiens, GI44680133, Length=188, Percent_Identity=28.7234042553192, Blast_Score=65, Evalue=4e-11,
Organism=Homo sapiens, GI17738292, Length=188, Percent_Identity=28.7234042553192, Blast_Score=65, Evalue=4e-11,
Organism=Escherichia coli, GI1787335, Length=242, Percent_Identity=43.801652892562, Blast_Score=198, Evalue=3e-52,
Organism=Escherichia coli, GI87082100, Length=251, Percent_Identity=36.2549800796813, Blast_Score=143, Evalue=1e-35,
Organism=Escherichia coli, GI1790717, Length=240, Percent_Identity=31.6666666666667, Blast_Score=115, Evalue=4e-27,
Organism=Escherichia coli, GI1789208, Length=242, Percent_Identity=30.1652892561983, Blast_Score=113, Evalue=1e-26,
Organism=Escherichia coli, GI1788459, Length=254, Percent_Identity=28.740157480315, Blast_Score=111, Evalue=6e-26,
Organism=Escherichia coli, GI87082160, Length=245, Percent_Identity=28.1632653061224, Blast_Score=103, Evalue=1e-23,
Organism=Escherichia coli, GI2367175, Length=244, Percent_Identity=28.6885245901639, Blast_Score=102, Evalue=2e-23,
Organism=Escherichia coli, GI1787820, Length=185, Percent_Identity=34.0540540540541, Blast_Score=97, Evalue=1e-21,
Organism=Escherichia coli, GI2367365, Length=241, Percent_Identity=29.045643153527, Blast_Score=92, Evalue=3e-20,
Organism=Escherichia coli, GI1786812, Length=204, Percent_Identity=27.9411764705882, Blast_Score=91, Evalue=6e-20,
Organism=Escherichia coli, GI1787905, Length=240, Percent_Identity=27.0833333333333, Blast_Score=89, Evalue=4e-19,
Organism=Escherichia coli, GI1789378, Length=252, Percent_Identity=26.5873015873016, Blast_Score=81, Evalue=7e-17,
Organism=Escherichia coli, GI1789057, Length=257, Percent_Identity=24.9027237354086, Blast_Score=77, Evalue=1e-15,
Organism=Escherichia coli, GI1786701, Length=191, Percent_Identity=26.7015706806283, Blast_Score=66, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI25147288, Length=244, Percent_Identity=41.3934426229508, Blast_Score=168, Evalue=2e-42,
Organism=Caenorhabditis elegans, GI17555706, Length=246, Percent_Identity=37.8048780487805, Blast_Score=164, Evalue=4e-41,
Organism=Caenorhabditis elegans, GI17560676, Length=247, Percent_Identity=29.1497975708502, Blast_Score=114, Evalue=7e-26,
Organism=Caenorhabditis elegans, GI17568967, Length=248, Percent_Identity=32.258064516129, Blast_Score=105, Evalue=2e-23,
Organism=Caenorhabditis elegans, GI17538182, Length=254, Percent_Identity=31.8897637795276, Blast_Score=103, Evalue=8e-23,
Organism=Caenorhabditis elegans, GI17561402, Length=250, Percent_Identity=29.2, Blast_Score=94, Evalue=6e-20,
Organism=Caenorhabditis elegans, GI71994600, Length=254, Percent_Identity=29.1338582677165, Blast_Score=92, Evalue=2e-19,
Organism=Caenorhabditis elegans, GI115534694, Length=240, Percent_Identity=27.9166666666667, Blast_Score=91, Evalue=6e-19,
Organism=Caenorhabditis elegans, GI71994604, Length=250, Percent_Identity=27.6, Blast_Score=89, Evalue=2e-18,
Organism=Caenorhabditis elegans, GI193203117, Length=196, Percent_Identity=31.6326530612245, Blast_Score=87, Evalue=9e-18,
Organism=Caenorhabditis elegans, GI193203115, Length=189, Percent_Identity=32.2751322751323, Blast_Score=87, Evalue=1e-17,
Organism=Caenorhabditis elegans, GI17536651, Length=252, Percent_Identity=28.968253968254, Blast_Score=82, Evalue=3e-16,
Organism=Caenorhabditis elegans, GI17562910, Length=264, Percent_Identity=29.5454545454545, Blast_Score=80, Evalue=7e-16,
Organism=Caenorhabditis elegans, GI17508651, Length=250, Percent_Identity=27.2, Blast_Score=79, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI17561272, Length=196, Percent_Identity=27.5510204081633, Blast_Score=79, Evalue=3e-15,
Organism=Caenorhabditis elegans, GI17536025, Length=251, Percent_Identity=27.8884462151394, Blast_Score=77, Evalue=7e-15,
Organism=Caenorhabditis elegans, GI193204405, Length=266, Percent_Identity=28.5714285714286, Blast_Score=77, Evalue=9e-15,
Organism=Caenorhabditis elegans, GI17559104, Length=263, Percent_Identity=26.9961977186312, Blast_Score=76, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI17560150, Length=255, Percent_Identity=29.0196078431373, Blast_Score=75, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI17562904, Length=252, Percent_Identity=28.1746031746032, Blast_Score=74, Evalue=6e-14,
Organism=Caenorhabditis elegans, GI17560332, Length=268, Percent_Identity=27.2388059701493, Blast_Score=74, Evalue=6e-14,
Organism=Caenorhabditis elegans, GI17562906, Length=266, Percent_Identity=28.9473684210526, Blast_Score=73, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI17562990, Length=185, Percent_Identity=31.3513513513514, Blast_Score=72, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI17562908, Length=270, Percent_Identity=28.1481481481481, Blast_Score=71, Evalue=4e-13,
Organism=Caenorhabditis elegans, GI17538486, Length=265, Percent_Identity=25.6603773584906, Blast_Score=71, Evalue=5e-13,
Organism=Caenorhabditis elegans, GI17551412, Length=269, Percent_Identity=26.3940520446097, Blast_Score=69, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17508895, Length=141, Percent_Identity=29.7872340425532, Blast_Score=68, Evalue=4e-12,
Organism=Caenorhabditis elegans, GI17544670, Length=265, Percent_Identity=24.5283018867925, Blast_Score=68, Evalue=5e-12,
Organism=Caenorhabditis elegans, GI17565030, Length=255, Percent_Identity=26.6666666666667, Blast_Score=68, Evalue=5e-12,
Organism=Caenorhabditis elegans, GI17563726, Length=184, Percent_Identity=25.5434782608696, Blast_Score=66, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI17531453, Length=278, Percent_Identity=26.2589928057554, Blast_Score=66, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI17564282, Length=137, Percent_Identity=27.7372262773723, Blast_Score=65, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI17538480, Length=271, Percent_Identity=25.4612546125461, Blast_Score=65, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI72000259, Length=199, Percent_Identity=26.6331658291457, Blast_Score=65, Evalue=4e-11,
Organism=Caenorhabditis elegans, GI32563809, Length=226, Percent_Identity=24.3362831858407, Blast_Score=65, Evalue=4e-11,
Organism=Caenorhabditis elegans, GI17507613, Length=226, Percent_Identity=24.3362831858407, Blast_Score=65, Evalue=4e-11,
Organism=Saccharomyces cerevisiae, GI6322861, Length=252, Percent_Identity=31.3492063492063, Blast_Score=105, Evalue=6e-24,
Organism=Saccharomyces cerevisiae, GI6324126, Length=255, Percent_Identity=26.6666666666667, Blast_Score=79, Evalue=7e-16,
Organism=Saccharomyces cerevisiae, GI6323882, Length=202, Percent_Identity=28.2178217821782, Blast_Score=72, Evalue=8e-14,
Organism=Drosophila melanogaster, GI24639444, Length=249, Percent_Identity=34.136546184739, Blast_Score=135, Evalue=2e-32,
Organism=Drosophila melanogaster, GI23397609, Length=253, Percent_Identity=33.201581027668, Blast_Score=118, Evalue=3e-27,
Organism=Drosophila melanogaster, GI24644339, Length=252, Percent_Identity=30.5555555555556, Blast_Score=108, Evalue=4e-24,
Organism=Drosophila melanogaster, GI28571526, Length=250, Percent_Identity=32, Blast_Score=105, Evalue=2e-23,
Organism=Drosophila melanogaster, GI21355319, Length=250, Percent_Identity=27.6, Blast_Score=105, Evalue=4e-23,
Organism=Drosophila melanogaster, GI21357041, Length=174, Percent_Identity=37.9310344827586, Blast_Score=104, Evalue=7e-23,
Organism=Drosophila melanogaster, GI17737361, Length=257, Percent_Identity=30.7392996108949, Blast_Score=99, Evalue=2e-21,
Organism=Drosophila melanogaster, GI24643142, Length=247, Percent_Identity=27.9352226720648, Blast_Score=96, Evalue=2e-20,
Organism=Drosophila melanogaster, GI18859837, Length=232, Percent_Identity=31.4655172413793, Blast_Score=92, Evalue=2e-19,
Organism=Drosophila melanogaster, GI21358495, Length=196, Percent_Identity=30.6122448979592, Blast_Score=83, Evalue=2e-16,
Organism=Drosophila melanogaster, GI24644337, Length=169, Percent_Identity=33.7278106508876, Blast_Score=83, Evalue=2e-16,
Organism=Drosophila melanogaster, GI24581726, Length=177, Percent_Identity=27.1186440677966, Blast_Score=74, Evalue=7e-14,
Organism=Drosophila melanogaster, GI24641232, Length=216, Percent_Identity=29.6296296296296, Blast_Score=73, Evalue=2e-13,
Organism=Drosophila melanogaster, GI24648693, Length=204, Percent_Identity=30.8823529411765, Blast_Score=69, Evalue=3e-12,
Organism=Drosophila melanogaster, GI21355889, Length=204, Percent_Identity=30.8823529411765, Blast_Score=69, Evalue=3e-12,
Organism=Drosophila melanogaster, GI116007236, Length=203, Percent_Identity=29.5566502463054, Blast_Score=69, Evalue=4e-12,
Organism=Drosophila melanogaster, GI24640442, Length=204, Percent_Identity=28.921568627451, Blast_Score=68, Evalue=7e-12,
Organism=Drosophila melanogaster, GI281364494, Length=199, Percent_Identity=27.6381909547739, Blast_Score=66, Evalue=2e-11,
Organism=Drosophila melanogaster, GI78706930, Length=215, Percent_Identity=28.8372093023256, Blast_Score=66, Evalue=2e-11,
Organism=Drosophila melanogaster, GI78706928, Length=215, Percent_Identity=28.8372093023256, Blast_Score=66, Evalue=2e-11,
Organism=Drosophila melanogaster, GI78706926, Length=215, Percent_Identity=28.8372093023256, Blast_Score=66, Evalue=2e-11,
Organism=Drosophila melanogaster, GI78706924, Length=215, Percent_Identity=28.8372093023256, Blast_Score=66, Evalue=2e-11,
Organism=Drosophila melanogaster, GI78706922, Length=215, Percent_Identity=28.8372093023256, Blast_Score=66, Evalue=2e-11,
Organism=Drosophila melanogaster, GI24641388, Length=205, Percent_Identity=31.7073170731707, Blast_Score=65, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011283
- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040
- InterPro:   IPR020904 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: =1.1.1.36 [H]

Molecular weight: Translated: 26508; Mature: 26377

Theoretical pI: Translated: 7.51; Mature: 7.51

Prosite motif: PS00061 ADH_SHORT

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSQRIAYVTGGMGGIGTSICQRLHKDGFRVVAGCGPNSPRRVKWLEDQKALGFDFYASEG
CCCEEEEEECCCCCHHHHHHHHHHHCCCEEEEECCCCCCCEEEEECCCCCCCEEEECCCC
NVGDWDSTKQAFDKVKAEVGEIDVLVNNAGITRDVVFRKMTREDWQAVIDTNLTSLFNVT
CCCCCHHHHHHHHHHHHHHCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHH
KQVIDGMVERGWGRIINISSVNGQKGQFGQTNYSTAKAGIHGFTMSLAQEVATKGVTVNT
HHHHHHHHHCCCCCEEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCEEEC
VSPGYIGTDMVKAIRPDVLEKIVATIPVRRLGSPDEIGSIVAWLASEESGFSTGADFSLN
CCCCCCCHHHHHHHCHHHHHHHHHHHCHHHCCCHHHHHHHHHHHHCCCCCCCCCCCEEEC
GGLHMG
CCCCCC
>Mature Secondary Structure 
SQRIAYVTGGMGGIGTSICQRLHKDGFRVVAGCGPNSPRRVKWLEDQKALGFDFYASEG
CCEEEEEECCCCCHHHHHHHHHHHCCCEEEEECCCCCCCEEEEECCCCCCCEEEECCCC
NVGDWDSTKQAFDKVKAEVGEIDVLVNNAGITRDVVFRKMTREDWQAVIDTNLTSLFNVT
CCCCCHHHHHHHHHHHHHHCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHH
KQVIDGMVERGWGRIINISSVNGQKGQFGQTNYSTAKAGIHGFTMSLAQEVATKGVTVNT
HHHHHHHHHCCCCCEEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCEEEC
VSPGYIGTDMVKAIRPDVLEKIVATIPVRRLGSPDEIGSIVAWLASEESGFSTGADFSLN
CCCCCCCHHHHHHHCHHHHHHHHHHHCHHHCCCHHHHHHHHHHHHCCCCCCCCCCCEEEC
GGLHMG
CCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2670935 [H]